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The map label for this gene is obg

Identifier: 162447231

GI number: 162447231

Start: 382164

End: 383423

Strand: Direct

Name: obg

Synonym: ACL_0365

Alternate gene names: 162447231

Gene position: 382164-383423 (Clockwise)

Preceding gene: 162447230

Following gene: 162447232

Centisome position: 25.53

GC content: 35.71

Gene sequence:

>1260_bases
ATGAGCGCATTTGTAGATGCAGTAACAGTAGAAGTAAAAGCAGGACGCGGTGGTAACGGTAAAGTTGCATTCCGTAGAGA
AGCACACGTGGAGTTTGGTGGACCCGCTGGTGGTAATGGTGGCCGTGGTGGTCATATTTACTTTATTGGTGATGAAGGTA
AAAATACGTTAATAGATTTAAAATACAACAGACATATCAAAGCTGCTAATGGTGTCCATGGTGGCCCTAAAGGGATGCAT
GGCGCACACGCAGAAGATACATATGTTCGTGTACCATTAGGTACAATTGTATATGATGATAAAGAAAATTTAATTGGTGA
AGTGTTAGAACATGGTCAAACTTTATTAATTGCTCAAGGTGGCAAAGGTGGCCGTGGTAATATGGCGTTTGCATCCAACA
ATAATAAAGCACCTGACTTTGCAGAACAAGGTGATTTAGGTCAAATATTCTTAGCAAAAGTAGAACTTCAAGTCCTAGCA
GATGTTGGTTTATTAGGTTATCCTAATGTTGGTAAATCGACTTTAATTACTAGAATCTCAAATGCAAAAGCTAAAATAGC
TGACTACCAATTTACAACACTATCTCCACAACTTGGTATGGTTAATGTGGAAGATGATGCGTTTGTTGTTGCAGACTTAC
CTGGATTAATTGAGTTTGCGCACCTTGGTGTTGGTTTAGGCTTACAATTCTTAAAACACGTTGAACGTTGTAGAGTTTTA
TTACATATCGTATCTATGGATTCATTAGATCCACTAGATGACTACAATAAGATTAACAATGAATTAGTGTTATATGATGA
AAAACTAAAAGACAGAACTCAAATAGTCGTAGCAAATAAGATGGACGTTGAAGGTGCACAAGAAAAGTTTGAAGCCTTCA
AAAAAGCATTAAAAGATGTTAAAGTTATTCCGATTTCAGCACTGATGAATGATGGTATTCAAACGCTTAAATATGAAATT
GCTACAACATTAAAAACTATCCCTAAATTTGCTCCAAAAGATACTACAAAACACTATACACTGAATGCAGAAGATGCAGT
AGATTTCATCATCAATAAAGGTGATGACGGTGTCTTTGAATTAACAGGTGATAAATTATTTGTTTTATTTAATAGAACAG
ACTTTAATAATGAATCAGCTGTGAAACGTTTTGCAAGACAGCTACGTGGTTTAGGTATCGAAGATGCACTTAGAGAACAT
GGTGTTGTTCATGGTGATATCGTACGTATCTTCTCTTATGAATTTGAATATTTAGAATAA

Upstream 100 bases:

>100_bases
AACCGTACGCAAGTATCAGTTTACGAAGCTTAATATTAAAAGGGTAATTGATTATTACCCTTTTTTGTTGTAAAATTTTA
GATACGAAGGAAGTGAAACA

Downstream 100 bases:

>100_bases
TCTAGTACTAATCCGAGCCCTATTAAGAGCTCGGATTTTTATTTTAAATACACTAAAGACCTAAGATTACCAACTAAGGA
CTTTGTACTTGAATTATTAT

Product: GTP-binding protein Obg/CgtA

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSAFVDAVTVEVKAGRGGNGKVAFRREAHVEFGGPAGGNGGRGGHIYFIGDEGKNTLIDLKYNRHIKAANGVHGGPKGMH
GAHAEDTYVRVPLGTIVYDDKENLIGEVLEHGQTLLIAQGGKGGRGNMAFASNNNKAPDFAEQGDLGQIFLAKVELQVLA
DVGLLGYPNVGKSTLITRISNAKAKIADYQFTTLSPQLGMVNVEDDAFVVADLPGLIEFAHLGVGLGLQFLKHVERCRVL
LHIVSMDSLDPLDDYNKINNELVLYDEKLKDRTQIVVANKMDVEGAQEKFEAFKKALKDVKVIPISALMNDGIQTLKYEI
ATTLKTIPKFAPKDTTKHYTLNAEDAVDFIINKGDDGVFELTGDKLFVLFNRTDFNNESAVKRFARQLRGLGIEDALREH
GVVHGDIVRIFSYEFEYLE

Sequences:

>Translated_419_residues
MSAFVDAVTVEVKAGRGGNGKVAFRREAHVEFGGPAGGNGGRGGHIYFIGDEGKNTLIDLKYNRHIKAANGVHGGPKGMH
GAHAEDTYVRVPLGTIVYDDKENLIGEVLEHGQTLLIAQGGKGGRGNMAFASNNNKAPDFAEQGDLGQIFLAKVELQVLA
DVGLLGYPNVGKSTLITRISNAKAKIADYQFTTLSPQLGMVNVEDDAFVVADLPGLIEFAHLGVGLGLQFLKHVERCRVL
LHIVSMDSLDPLDDYNKINNELVLYDEKLKDRTQIVVANKMDVEGAQEKFEAFKKALKDVKVIPISALMNDGIQTLKYEI
ATTLKTIPKFAPKDTTKHYTLNAEDAVDFIINKGDDGVFELTGDKLFVLFNRTDFNNESAVKRFARQLRGLGIEDALREH
GVVHGDIVRIFSYEFEYLE
>Mature_418_residues
SAFVDAVTVEVKAGRGGNGKVAFRREAHVEFGGPAGGNGGRGGHIYFIGDEGKNTLIDLKYNRHIKAANGVHGGPKGMHG
AHAEDTYVRVPLGTIVYDDKENLIGEVLEHGQTLLIAQGGKGGRGNMAFASNNNKAPDFAEQGDLGQIFLAKVELQVLAD
VGLLGYPNVGKSTLITRISNAKAKIADYQFTTLSPQLGMVNVEDDAFVVADLPGLIEFAHLGVGLGLQFLKHVERCRVLL
HIVSMDSLDPLDDYNKINNELVLYDEKLKDRTQIVVANKMDVEGAQEKFEAFKKALKDVKVIPISALMNDGIQTLKYEIA
TTLKTIPKFAPKDTTKHYTLNAEDAVDFIINKGDDGVFELTGDKLFVLFNRTDFNNESAVKRFARQLRGLGIEDALREHG
VVHGDIVRIFSYEFEYLE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=314, Percent_Identity=38.5350318471338, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI111955139, Length=310, Percent_Identity=34.8387096774194, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI111955063, Length=188, Percent_Identity=38.8297872340425, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=31.8518518518519, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4758796, Length=103, Percent_Identity=36.8932038834951, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1789574, Length=329, Percent_Identity=44.0729483282675, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=31.1594202898551, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=318, Percent_Identity=40.5660377358491, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17552324, Length=325, Percent_Identity=32, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=103, Percent_Identity=33.9805825242718, Blast_Score=65, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=41.2371134020619, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319281, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129375, Length=311, Percent_Identity=39.2282958199357, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24585318, Length=355, Percent_Identity=32.6760563380282, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17981711, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_ACHLI (A9NF57)

Other databases:

- EMBL:   CP000896
- RefSeq:   YP_001620363.1
- ProteinModelPortal:   A9NF57
- SMR:   A9NF57
- GeneID:   5804357
- GenomeReviews:   CP000896_GR
- KEGG:   acl:ACL_0365
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- BioCyc:   ALAI441768:ACL_0365-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 45873; Mature: 45742

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFVDAVTVEVKAGRGGNGKVAFRREAHVEFGGPAGGNGGRGGHIYFIGDEGKNTLIDL
CCCCEEEEEEEEEECCCCCCCEEEEEECEEEECCCCCCCCCCCCEEEEEECCCCCEEEEE
KYNRHIKAANGVHGGPKGMHGAHAEDTYVRVPLGTIVYDDKENLIGEVLEHGQTLLIAQG
EECCEEEECCCCCCCCCCCCCCCCCCCEEEEEECEEEECCHHHHHHHHHHCCCEEEEEEC
GKGGRGNMAFASNNNKAPDFAEQGDLGQIFLAKVELQVLADVGLLGYPNVGKSTLITRIS
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHEECC
NAKAKIADYQFTTLSPQLGMVNVEDDAFVVADLPGLIEFAHLGVGLGLQFLKHVERCRVL
CCCEEEEEEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LHIVSMDSLDPLDDYNKINNELVLYDEKLKDRTQIVVANKMDVEGAQEKFEAFKKALKDV
HHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
KVIPISALMNDGIQTLKYEIATTLKTIPKFAPKDTTKHYTLNAEDAVDFIINKGDDGVFE
EEEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHCEEEEEECCCCCEEE
LTGDKLFVLFNRTDFNNESAVKRFARQLRGLGIEDALREHGVVHGDIVRIFSYEFEYLE
ECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEEHHEEEEEEEECEECC
>Mature Secondary Structure 
SAFVDAVTVEVKAGRGGNGKVAFRREAHVEFGGPAGGNGGRGGHIYFIGDEGKNTLIDL
CCCEEEEEEEEEECCCCCCCEEEEEECEEEECCCCCCCCCCCCEEEEEECCCCCEEEEE
KYNRHIKAANGVHGGPKGMHGAHAEDTYVRVPLGTIVYDDKENLIGEVLEHGQTLLIAQG
EECCEEEECCCCCCCCCCCCCCCCCCCEEEEEECEEEECCHHHHHHHHHHCCCEEEEEEC
GKGGRGNMAFASNNNKAPDFAEQGDLGQIFLAKVELQVLADVGLLGYPNVGKSTLITRIS
CCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCHHHHEECC
NAKAKIADYQFTTLSPQLGMVNVEDDAFVVADLPGLIEFAHLGVGLGLQFLKHVERCRVL
CCCEEEEEEEEEEECCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LHIVSMDSLDPLDDYNKINNELVLYDEKLKDRTQIVVANKMDVEGAQEKFEAFKKALKDV
HHHHCCCCCCCCHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
KVIPISALMNDGIQTLKYEIATTLKTIPKFAPKDTTKHYTLNAEDAVDFIINKGDDGVFE
EEEEHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHCEEEEEECCCCCEEE
LTGDKLFVLFNRTDFNNESAVKRFARQLRGLGIEDALREHGVVHGDIVRIFSYEFEYLE
ECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEEHHEEEEEEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA