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The map label for this gene is sftA [H]

Identifier: 162447202

GI number: 162447202

Start: 347555

End: 349414

Strand: Direct

Name: sftA [H]

Synonym: ACL_0336

Alternate gene names: 162447202

Gene position: 347555-349414 (Clockwise)

Preceding gene: 162447201

Following gene: 162447203

Centisome position: 23.22

GC content: 34.03

Gene sequence:

>1860_bases
ATGGATGATGATGCCAATATTCAAAAAACTGGTAATAAATATTATGAATTTAAAGATGGTATTATTTCTAAAGAAACTAG
AAAACAAATTTTCGGTATAGATTCTTATAAACATAAAAACCAAGATGCACCTGTAAAAGAAGATGTAGCCTTTGAACCAA
AAATTGAAGAAGAGATTCAACCAATTAAAATGAATCACGTGGAAACACCTGAAAATACACTACCACCTTGGATGCGTGGT
AAACATATTGAGACAACACCAGAAATTGGTGGTCTTGATGTGGATACATTTAAGCGTCCAAGTAAAGGAATTCAAATTAA
AGCTAATTTTGGTGAGGAAATTAGTGAAGATTATCCAGAACAAGCACCCCCTAAATATGTTGAACCTAAGAAAACGGAAG
TTAGACAAGCATTTAGAGCACACACACCTACTAGTAATTATCAACTGCCACCATTAACATTACTTAAAAAAGTAGAAAGA
AGCGCAGATGATAAACCTGAATGGTTAGTAGAACAAGTTGAACGTATTAATCAAACCTTAATTGATCACGCTGTTGAAGG
TGAAGTGGCTCAATCTAAAAAAGGTCCAACAGTTACAAGACATGAGATTTCTCTAGAACCTGGTGTTCCGGTAAAACGTA
TTACAAGTCTTCAAGATAACTTAATGATGAATTTAGCTGCTAAAACACTACGTATTGAAGCACCAATTCCTGGTAAACCA
TTTGTTGGTATTGAAGTACCAAATAAGATTGCTGATATAGTATCCTTTGGTAATGTTGTAGATACAGATGAATTTTTAGA
AGATCATAAACATCCACTTAAAGTAGCTTTAGGGGAAGATATTGATGGTACAAACATTTATGTAGATATCGCTAAAATGC
CACACGGTTTAATCGCTGGTGGTACCGGATCTGGTAAGTCTGTTTGTGTGAACTCCATATTAATTTCTTTATTATTAAAG
AACAGACCAGAGGACTTAAAACTAATTTTAATTGACCCTAAAATGGTAGAACTTACACCTTATAATGATCTACCTCATTT
AATCACGCCTGTTATTACAGATCCAAAAATGGCTGCAACAGCACTAAACTGGGTTGTTGATGAAATGGAAGATCGCTATA
AAAAATTTGCAGGTACAAGATCAAGAGATATAGGTAGTTTTAATGAGAATGTTAAAAAGGGATTTATTGATGAACAAAAA
ATGCCTTTAATTTTAATCGTCATTGATGAGTTAGCTGACCTTATGATGGTTGCTGCACATGATGTTGAAAATGCTATTCA
ACGTATCACTCAAAAAGCACGTGCAGCAGGGATTCACTTACTTGTAGCAACACAAAGACCAACAGTCGATGTCATTAGAG
GTACGATAAAGTCAAATATTCCTACACGTATTGCATTTAGAGTGGCAAGCTTTACAGACTCTACAACCATTTTAGATGGT
GCAGGGGCTGAGCAATTACTTGGTCGAGGCGATATGCTTTTAAAAGAAGCTGAAAGACCAATTAGATTACAAGGTGCTTA
TATTTCAAATAACGAAATTGATGCCGTTATTGATTTTATCAGACAACAAACAACGCCACAATATATCTTAAAACATGAAG
ATTTAAGACATATTGTACAAGCAAAAGATACCATTGATGATGATCTATTCGCACAAGTTGCAGAATATGTAGTAAGTGAA
AATAGTTGTTCTATCAATGGTATTCAAAAAGAATATAATATTGGTTTTAACCGTGCACAAAAAATAGCTACCTTATTAGA
ACAATATGGTATTGTCTCCCCTGCACAAGGAACCAAAGCGCGTGAAGTCTTAATTGATATGTTAAGCTTACGAGAAATTT
TAGAAAAGTTGGGATTATAA

Upstream 100 bases:

>100_bases
TTTTGGTAGTGACGTAAAAGATGAAATTCATGTACCGTTTGTTGTCAGAGTCATTGGTGATAAGGTAAAAAAATATGACG
CCTTTAGAACTGTACCTAAA

Downstream 100 bases:

>100_bases
TGAAACAGGTTCAATGGTTTCCAGGACATATGTTCAAGTCCTTGAGAGAAATCAAGGAAAAAATTAAACTCATGGATATG
GTATTTTTGCTCGTTGATGC

Product: FtsK/SpoIIIE family protein

Products: NA

Alternate protein names: Septum-associated ftsK-like translocase of DNA [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MDDDANIQKTGNKYYEFKDGIISKETRKQIFGIDSYKHKNQDAPVKEDVAFEPKIEEEIQPIKMNHVETPENTLPPWMRG
KHIETTPEIGGLDVDTFKRPSKGIQIKANFGEEISEDYPEQAPPKYVEPKKTEVRQAFRAHTPTSNYQLPPLTLLKKVER
SADDKPEWLVEQVERINQTLIDHAVEGEVAQSKKGPTVTRHEISLEPGVPVKRITSLQDNLMMNLAAKTLRIEAPIPGKP
FVGIEVPNKIADIVSFGNVVDTDEFLEDHKHPLKVALGEDIDGTNIYVDIAKMPHGLIAGGTGSGKSVCVNSILISLLLK
NRPEDLKLILIDPKMVELTPYNDLPHLITPVITDPKMAATALNWVVDEMEDRYKKFAGTRSRDIGSFNENVKKGFIDEQK
MPLILIVIDELADLMMVAAHDVENAIQRITQKARAAGIHLLVATQRPTVDVIRGTIKSNIPTRIAFRVASFTDSTTILDG
AGAEQLLGRGDMLLKEAERPIRLQGAYISNNEIDAVIDFIRQQTTPQYILKHEDLRHIVQAKDTIDDDLFAQVAEYVVSE
NSCSINGIQKEYNIGFNRAQKIATLLEQYGIVSPAQGTKAREVLIDMLSLREILEKLGL

Sequences:

>Translated_619_residues
MDDDANIQKTGNKYYEFKDGIISKETRKQIFGIDSYKHKNQDAPVKEDVAFEPKIEEEIQPIKMNHVETPENTLPPWMRG
KHIETTPEIGGLDVDTFKRPSKGIQIKANFGEEISEDYPEQAPPKYVEPKKTEVRQAFRAHTPTSNYQLPPLTLLKKVER
SADDKPEWLVEQVERINQTLIDHAVEGEVAQSKKGPTVTRHEISLEPGVPVKRITSLQDNLMMNLAAKTLRIEAPIPGKP
FVGIEVPNKIADIVSFGNVVDTDEFLEDHKHPLKVALGEDIDGTNIYVDIAKMPHGLIAGGTGSGKSVCVNSILISLLLK
NRPEDLKLILIDPKMVELTPYNDLPHLITPVITDPKMAATALNWVVDEMEDRYKKFAGTRSRDIGSFNENVKKGFIDEQK
MPLILIVIDELADLMMVAAHDVENAIQRITQKARAAGIHLLVATQRPTVDVIRGTIKSNIPTRIAFRVASFTDSTTILDG
AGAEQLLGRGDMLLKEAERPIRLQGAYISNNEIDAVIDFIRQQTTPQYILKHEDLRHIVQAKDTIDDDLFAQVAEYVVSE
NSCSINGIQKEYNIGFNRAQKIATLLEQYGIVSPAQGTKAREVLIDMLSLREILEKLGL
>Mature_619_residues
MDDDANIQKTGNKYYEFKDGIISKETRKQIFGIDSYKHKNQDAPVKEDVAFEPKIEEEIQPIKMNHVETPENTLPPWMRG
KHIETTPEIGGLDVDTFKRPSKGIQIKANFGEEISEDYPEQAPPKYVEPKKTEVRQAFRAHTPTSNYQLPPLTLLKKVER
SADDKPEWLVEQVERINQTLIDHAVEGEVAQSKKGPTVTRHEISLEPGVPVKRITSLQDNLMMNLAAKTLRIEAPIPGKP
FVGIEVPNKIADIVSFGNVVDTDEFLEDHKHPLKVALGEDIDGTNIYVDIAKMPHGLIAGGTGSGKSVCVNSILISLLLK
NRPEDLKLILIDPKMVELTPYNDLPHLITPVITDPKMAATALNWVVDEMEDRYKKFAGTRSRDIGSFNENVKKGFIDEQK
MPLILIVIDELADLMMVAAHDVENAIQRITQKARAAGIHLLVATQRPTVDVIRGTIKSNIPTRIAFRVASFTDSTTILDG
AGAEQLLGRGDMLLKEAERPIRLQGAYISNNEIDAVIDFIRQQTTPQYILKHEDLRHIVQAKDTIDDDLFAQVAEYVVSE
NSCSINGIQKEYNIGFNRAQKIATLLEQYGIVSPAQGTKAREVLIDMLSLREILEKLGL

Specific function: Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cy

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cytoplasm. Note=Colocalizes with ftsZ at nascent division sites [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=493, Percent_Identity=42.393509127789, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 69258; Mature: 69258

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00227 TUBULIN ; PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDDANIQKTGNKYYEFKDGIISKETRKQIFGIDSYKHKNQDAPVKEDVAFEPKIEEEIQ
CCCCCCCHHCCCEEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PIKMNHVETPENTLPPWMRGKHIETTPEIGGLDVDTFKRPSKGIQIKANFGEEISEDYPE
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHCCCC
QAPPKYVEPKKTEVRQAFRAHTPTSNYQLPPLTLLKKVERSADDKPEWLVEQVERINQTL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IDHAVEGEVAQSKKGPTVTRHEISLEPGVPVKRITSLQDNLMMNLAAKTLRIEAPIPGKP
HHHHHCCCHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
FVGIEVPNKIADIVSFGNVVDTDEFLEDHKHPLKVALGEDIDGTNIYVDIAKMPHGLIAG
EEEEECCHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCEEEC
GTGSGKSVCVNSILISLLLKNRPEDLKLILIDPKMVELTPYNDLPHLITPVITDPKMAAT
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCHHHHCCCCCCHHHHH
ALNWVVDEMEDRYKKFAGTRSRDIGSFNENVKKGFIDEQKMPLILIVIDELADLMMVAAH
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHH
DVENAIQRITQKARAAGIHLLVATQRPTVDVIRGTIKSNIPTRIAFRVASFTDSTTILDG
HHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECC
AGAEQLLGRGDMLLKEAERPIRLQGAYISNNEIDAVIDFIRQQTTPQYILKHEDLRHIVQ
CCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKDTIDDDLFAQVAEYVVSENSCSINGIQKEYNIGFNRAQKIATLLEQYGIVSPAQGTKA
HHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHH
REVLIDMLSLREILEKLGL
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDDDANIQKTGNKYYEFKDGIISKETRKQIFGIDSYKHKNQDAPVKEDVAFEPKIEEEIQ
CCCCCCCHHCCCEEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PIKMNHVETPENTLPPWMRGKHIETTPEIGGLDVDTFKRPSKGIQIKANFGEEISEDYPE
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHCCCC
QAPPKYVEPKKTEVRQAFRAHTPTSNYQLPPLTLLKKVERSADDKPEWLVEQVERINQTL
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
IDHAVEGEVAQSKKGPTVTRHEISLEPGVPVKRITSLQDNLMMNLAAKTLRIEAPIPGKP
HHHHHCCCHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
FVGIEVPNKIADIVSFGNVVDTDEFLEDHKHPLKVALGEDIDGTNIYVDIAKMPHGLIAG
EEEEECCHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCEEEC
GTGSGKSVCVNSILISLLLKNRPEDLKLILIDPKMVELTPYNDLPHLITPVITDPKMAAT
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCHHHHCCCCCCHHHHH
ALNWVVDEMEDRYKKFAGTRSRDIGSFNENVKKGFIDEQKMPLILIVIDELADLMMVAAH
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHH
DVENAIQRITQKARAAGIHLLVATQRPTVDVIRGTIKSNIPTRIAFRVASFTDSTTILDG
HHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECC
AGAEQLLGRGDMLLKEAERPIRLQGAYISNNEIDAVIDFIRQQTTPQYILKHEDLRHIVQ
CCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AKDTIDDDLFAQVAEYVVSENSCSINGIQKEYNIGFNRAQKIATLLEQYGIVSPAQGTKA
HHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHH
REVLIDMLSLREILEKLGL
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]