Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 162447096

GI number: 162447096

Start: 217428

End: 219377

Strand: Direct

Name: recG [H]

Synonym: ACL_0226

Alternate gene names: 162447096

Gene position: 217428-219377 (Clockwise)

Preceding gene: 162447094

Following gene: 162447097

Centisome position: 14.52

GC content: 31.49

Gene sequence:

>1950_bases
ATGATTAGAGATCTTAGTTTAATCCCAGGTGTGGGACCTAAAAATTTAAAAACATTTAAGCGTCATGGTATTTCTAATAC
TTATGATCTTGTAACTAATTTACCTAAGAAATATGAAAACTTTTCTCTGGTAGATGTAGAAAATCTAAAGCACTTAGAAG
AAGCTACCATTATTGGTTTAATTAGTGCGCCTTTTTATACTGTAAAAAAGCGTGTTGTGTTAACAACTACGACCTTACTT
GTTCAAGATAAGGTTGTTAAACTACTTATCTTTGGAAGAGACTACATTTCAAAAGAGTTTAGTCTCAATGATAAGGTCAT
CGTAAAGGGTAAGTATAATATGTTTAAAAACGAGATCAATGTCACATATATCTCAAAAAAAATAGATACACCCAATATTC
AACCTAAATATCAAATTGAACATATAAGTGACAGAACCATTCAAAAAATGATTGAATACGTATTTTCAAATAACTTGGTA
GATGTTTTTGAAACACTACCAACTAAGTTTATTGAACATGAAAAACTTATGCATAGAAAAACTGCAATTTTAACGATGCA
TTTTCCTAAAAATGAAACGGATTTAGAAATTGCTCAATATAGATTTAAAGTAGAAGAAGCTTTCTTCCATCTTATGAAAT
ATCATTTGAGTATGCCACCTAAACTAAAAAGAACACCACTATCATATGATATCGGTTGGGTTAAGGAACAAATTAGTTTA
TTACCTTACCAATTGACATTAGATCAACAAGAAGCTGTCAATGATTGTTTTAGAGATTTTAAAAGTGATTATTCAATGTA
TAGATTAATTCAAGGTGATGTTGGTACTGGTAAAACATTTGTCACATTCATTGCAGCATTAGGTGCAATATCAGCGGGAT
ACCAAGTAGCCTTTTTAGCACCAACAGAAATTTTAGCAAGACAACACTATGAAAACTTTAATAAGCATTTTGGTCATCTA
CCAAGTGGATTACTGACATCCTCATTAAAGGATAAGAAAGAAACCATGAATCGTTTAAATTCAAATGATGTCAACATTGT
TTTTGGTACCCATATCCTAAGTTCAGAAGCTGTTATCTTTGACAAACTTGGATTAGTTGTGATTGATGAACAGCACAAAT
TTGGCGTTGAAACTAGAGAAAGTCTAATTAAAAAAAGCGTCACAGGTGATACGATTTATCTTTCTGCAACACCAATTCCA
AGAAGTTTATCACTGACCTATTTTGGCAGTTTAGAAGTGTCCAACATCAAACAAAAACCGGTTAACACACCACCAATTGA
ATCTTACTTATTAGATGACAAAGATATATCTAAAATTATTGCAGCACTTAAGGTTGCAGGGCAAAACAATGAACAAAGTT
TTATTGTAGTACCTGCAATTTCAGAAGGGAATAAATCACACTCTATTCACAGCGTATTTTCAATTTTAGAACCTCACTTT
AACCCGGATAACTTTTATGTCATTCATGGTCAACTAAAATATGAGGAAATTGAACTTATTATGGACAGATTCATGCAAAA
TCCCAAAGGTATATTATTATCAACAACCATCATTGAAGTTGGTATCGATGTTAAAAATGCCAGTACAATCATCATTATGG
GTGCAGATAACTTTGGGTTATCTCAACTACACCAATTACGTGGACGTGTTGGTAGAGGTTCTATTCCAGGTAAGTGTTAT
TTTGTAAGTTCTAAAAAGGATGTTGAAAGACTAAACTTTTTACTACAGACAACTGATGGATTCTTACTCAGTCAATATGA
CTTAAAACTTCGTGGCCCGGGTGTTTTTTCATCGATTATTCAAAGTGGTTATACAAGGTTCGAATATCTTGATTTAAATA
CAGATTTAAAACTTTTACAAGGCATTGTAAAGGATGTAAAGTACTATGTAGAAAATATTGAAAAATATCCGTATTTGAAA
AAAAGAATTTTCAAATCGAACGTGATATAA

Upstream 100 bases:

>100_bases
GATTTTTGGTATGAAACTTATACCTTTTTAGGTATGAAATTCTTTAAGTAAAATAGCTTACTATGACCTGAACTTGAACT
ATACATGCTATAATTTAGTT

Downstream 100 bases:

>100_bases
TCAATATAGTAATGCTTTAGAAGGGATGATTTAATATATGATAAAACTAGCAATTGATGGTATGGGTGGCGACAACGCAC
CTAAAGAAATAGTAGAGGGC

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MIRDLSLIPGVGPKNLKTFKRHGISNTYDLVTNLPKKYENFSLVDVENLKHLEEATIIGLISAPFYTVKKRVVLTTTTLL
VQDKVVKLLIFGRDYISKEFSLNDKVIVKGKYNMFKNEINVTYISKKIDTPNIQPKYQIEHISDRTIQKMIEYVFSNNLV
DVFETLPTKFIEHEKLMHRKTAILTMHFPKNETDLEIAQYRFKVEEAFFHLMKYHLSMPPKLKRTPLSYDIGWVKEQISL
LPYQLTLDQQEAVNDCFRDFKSDYSMYRLIQGDVGTGKTFVTFIAALGAISAGYQVAFLAPTEILARQHYENFNKHFGHL
PSGLLTSSLKDKKETMNRLNSNDVNIVFGTHILSSEAVIFDKLGLVVIDEQHKFGVETRESLIKKSVTGDTIYLSATPIP
RSLSLTYFGSLEVSNIKQKPVNTPPIESYLLDDKDISKIIAALKVAGQNNEQSFIVVPAISEGNKSHSIHSVFSILEPHF
NPDNFYVIHGQLKYEEIELIMDRFMQNPKGILLSTTIIEVGIDVKNASTIIIMGADNFGLSQLHQLRGRVGRGSIPGKCY
FVSSKKDVERLNFLLQTTDGFLLSQYDLKLRGPGVFSSIIQSGYTRFEYLDLNTDLKLLQGIVKDVKYYVENIEKYPYLK
KRIFKSNVI

Sequences:

>Translated_649_residues
MIRDLSLIPGVGPKNLKTFKRHGISNTYDLVTNLPKKYENFSLVDVENLKHLEEATIIGLISAPFYTVKKRVVLTTTTLL
VQDKVVKLLIFGRDYISKEFSLNDKVIVKGKYNMFKNEINVTYISKKIDTPNIQPKYQIEHISDRTIQKMIEYVFSNNLV
DVFETLPTKFIEHEKLMHRKTAILTMHFPKNETDLEIAQYRFKVEEAFFHLMKYHLSMPPKLKRTPLSYDIGWVKEQISL
LPYQLTLDQQEAVNDCFRDFKSDYSMYRLIQGDVGTGKTFVTFIAALGAISAGYQVAFLAPTEILARQHYENFNKHFGHL
PSGLLTSSLKDKKETMNRLNSNDVNIVFGTHILSSEAVIFDKLGLVVIDEQHKFGVETRESLIKKSVTGDTIYLSATPIP
RSLSLTYFGSLEVSNIKQKPVNTPPIESYLLDDKDISKIIAALKVAGQNNEQSFIVVPAISEGNKSHSIHSVFSILEPHF
NPDNFYVIHGQLKYEEIELIMDRFMQNPKGILLSTTIIEVGIDVKNASTIIIMGADNFGLSQLHQLRGRVGRGSIPGKCY
FVSSKKDVERLNFLLQTTDGFLLSQYDLKLRGPGVFSSIIQSGYTRFEYLDLNTDLKLLQGIVKDVKYYVENIEKYPYLK
KRIFKSNVI
>Mature_649_residues
MIRDLSLIPGVGPKNLKTFKRHGISNTYDLVTNLPKKYENFSLVDVENLKHLEEATIIGLISAPFYTVKKRVVLTTTTLL
VQDKVVKLLIFGRDYISKEFSLNDKVIVKGKYNMFKNEINVTYISKKIDTPNIQPKYQIEHISDRTIQKMIEYVFSNNLV
DVFETLPTKFIEHEKLMHRKTAILTMHFPKNETDLEIAQYRFKVEEAFFHLMKYHLSMPPKLKRTPLSYDIGWVKEQISL
LPYQLTLDQQEAVNDCFRDFKSDYSMYRLIQGDVGTGKTFVTFIAALGAISAGYQVAFLAPTEILARQHYENFNKHFGHL
PSGLLTSSLKDKKETMNRLNSNDVNIVFGTHILSSEAVIFDKLGLVVIDEQHKFGVETRESLIKKSVTGDTIYLSATPIP
RSLSLTYFGSLEVSNIKQKPVNTPPIESYLLDDKDISKIIAALKVAGQNNEQSFIVVPAISEGNKSHSIHSVFSILEPHF
NPDNFYVIHGQLKYEEIELIMDRFMQNPKGILLSTTIIEVGIDVKNASTIIIMGADNFGLSQLHQLRGRVGRGSIPGKCY
FVSSKKDVERLNFLLQTTDGFLLSQYDLKLRGPGVFSSIIQSGYTRFEYLDLNTDLKLLQGIVKDVKYYVENIEKYPYLK
KRIFKSNVI

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=573, Percent_Identity=32.9842931937173, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1787357, Length=399, Percent_Identity=32.3308270676692, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74095; Mature: 74095

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDLSLIPGVGPKNLKTFKRHGISNTYDLVTNLPKKYENFSLVDVENLKHLEEATIIGL
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHCCHHHHCCCEEEEHHHHHHHHHHHEEEE
ISAPFYTVKKRVVLTTTTLLVQDKVVKLLIFGRDYISKEFSLNDKVIVKGKYNMFKNEIN
ECCCHHHHHCEEEEEEHHHHHHHHHHHHHEECHHHHCCCCCCCCEEEEEECHHHHHCCEE
VTYISKKIDTPNIQPKYQIEHISDRTIQKMIEYVFSNNLVDVFETLPTKFIEHEKLMHRK
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
TAILTMHFPKNETDLEIAQYRFKVEEAFFHLMKYHLSMPPKLKRTPLSYDIGWVKEQISL
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LPYQLTLDQQEAVNDCFRDFKSDYSMYRLIQGDVGTGKTFVTFIAALGAISAGYQVAFLA
CCEEEECCHHHHHHHHHHHHHCCHHEEHHEECCCCCCHHHHHHHHHHHHHCCCCEEEEEC
PTEILARQHYENFNKHFGHLPSGLLTSSLKDKKETMNRLNSNDVNIVFGTHILSSEAVIF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEE
DKLGLVVIDEQHKFGVETRESLIKKSVTGDTIYLSATPIPRSLSLTYFGSLEVSNIKQKP
ECCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECEEECCCCCCC
VNTPPIESYLLDDKDISKIIAALKVAGQNNEQSFIVVPAISEGNKSHSIHSVFSILEPHF
CCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCC
NPDNFYVIHGQLKYEEIELIMDRFMQNPKGILLSTTIIEVGIDVKNASTIIIMGADNFGL
CCCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEEEEEECEECCCCEEEEEECCCCCH
SQLHQLRGRVGRGSIPGKCYFVSSKKDVERLNFLLQTTDGFLLSQYDLKLRGPGVFSSII
HHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECEEEECCHHHHHHH
QSGYTRFEYLDLNTDLKLLQGIVKDVKYYVENIEKYPYLKKRIFKSNVI
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
>Mature Secondary Structure
MIRDLSLIPGVGPKNLKTFKRHGISNTYDLVTNLPKKYENFSLVDVENLKHLEEATIIGL
CCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHCCHHHHCCCEEEEHHHHHHHHHHHEEEE
ISAPFYTVKKRVVLTTTTLLVQDKVVKLLIFGRDYISKEFSLNDKVIVKGKYNMFKNEIN
ECCCHHHHHCEEEEEEHHHHHHHHHHHHHEECHHHHCCCCCCCCEEEEEECHHHHHCCEE
VTYISKKIDTPNIQPKYQIEHISDRTIQKMIEYVFSNNLVDVFETLPTKFIEHEKLMHRK
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
TAILTMHFPKNETDLEIAQYRFKVEEAFFHLMKYHLSMPPKLKRTPLSYDIGWVKEQISL
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LPYQLTLDQQEAVNDCFRDFKSDYSMYRLIQGDVGTGKTFVTFIAALGAISAGYQVAFLA
CCEEEECCHHHHHHHHHHHHHCCHHEEHHEECCCCCCHHHHHHHHHHHHHCCCCEEEEEC
PTEILARQHYENFNKHFGHLPSGLLTSSLKDKKETMNRLNSNDVNIVFGTHILSSEAVIF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEE
DKLGLVVIDEQHKFGVETRESLIKKSVTGDTIYLSATPIPRSLSLTYFGSLEVSNIKQKP
ECCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECEEECCCCCCC
VNTPPIESYLLDDKDISKIIAALKVAGQNNEQSFIVVPAISEGNKSHSIHSVFSILEPHF
CCCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCC
NPDNFYVIHGQLKYEEIELIMDRFMQNPKGILLSTTIIEVGIDVKNASTIIIMGADNFGL
CCCCEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEEEEEEECEECCCCEEEEEECCCCCH
SQLHQLRGRVGRGSIPGKCYFVSSKKDVERLNFLLQTTDGFLLSQYDLKLRGPGVFSSII
HHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECEEEECCHHHHHHH
QSGYTRFEYLDLNTDLKLLQGIVKDVKYYVENIEKYPYLKKRIFKSNVI
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]