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The map label for this gene is aroE [H]

Identifier: 162447090

GI number: 162447090

Start: 211709

End: 212491

Strand: Direct

Name: aroE [H]

Synonym: ACL_0220

Alternate gene names: 162447090

Gene position: 211709-212491 (Clockwise)

Preceding gene: 162447089

Following gene: 162447091

Centisome position: 14.14

GC content: 30.52

Gene sequence:

>783_bases
ATGAAAGTATTTGGATTAATTGGACATCCATTAGGGCACTCTAAGTCGCCTAAATTACATAAAATCATTGCTAGTTATTT
TAGTAGACAACTAGTTTATAAATTATTTGATATGGATCACATCGATAAAGTAAAACCATTGATTGAAGGGTTAAAAAATG
GTACATATCATGGTTTTAATGTAACCATTCCATATAAGGAAGCAGTGCTTCCCTTTTTGGATATCATAACACCTAAAGCT
CAAAAGATAGGTGCAGTAAACACTATCTATTTTAAAGATAATCAAGTCATAGGTGACAACACTGATTATGATGGTTTTTT
ATATTTAATTAAACAACAATCTATAATAAAAAAAATCATGAACCCTATTATATTAGGTAGTGGTGGTGCAGCAAAATCAA
GTTATGCGGTGTTAAAAGATCTTGGATTTGACTCGGTTGTTGTATCAAGAAATCCAAAGGATAATGTGCACTTTAATCAC
ATCATAAGTTATGATAAACTACCAAGTTACTCATATGATTTGGTTGTAAACACGACACCAATTGGGATGCATCCAAATAT
TAACCAATCGCCACTGGATGAAAGTTTAGTACATGATAAATTTGTTATAGATCTCATCTATAATCCACTGGAAACTACTT
TAATGAAATATGCTAAACATAGTATTGGTGGACTTGATATGCTCATTGTTCAAGCATTTAAAGCTCAAAATATATGGTTT
GGTGAAGAAAAAGAATTAAAAGATGATATATTAAATCATATCAAGGAGGACGTATATGAATAG

Upstream 100 bases:

>100_bases
TACTTCAAAAGAAAAAGGAACAACTCTCCAATAAGGACTTATGGCCTCACTTTGAAAAGTTGTTTCAACATATTATGAAT
ATCTCAAAAGAATTAGAAAA

Downstream 100 bases:

>100_bases
TTTCGGCACTTTATTTAAAGTAACTTTATATGGTGAATCACATCAAGATGCTATAGGTATAGTTATTGATGGTGTAAAAC
CCGGTCTTAAAATTAACTGG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKVFGLIGHPLGHSKSPKLHKIIASYFSRQLVYKLFDMDHIDKVKPLIEGLKNGTYHGFNVTIPYKEAVLPFLDIITPKA
QKIGAVNTIYFKDNQVIGDNTDYDGFLYLIKQQSIIKKIMNPIILGSGGAAKSSYAVLKDLGFDSVVVSRNPKDNVHFNH
IISYDKLPSYSYDLVVNTTPIGMHPNINQSPLDESLVHDKFVIDLIYNPLETTLMKYAKHSIGGLDMLIVQAFKAQNIWF
GEEKELKDDILNHIKEDVYE

Sequences:

>Translated_260_residues
MKVFGLIGHPLGHSKSPKLHKIIASYFSRQLVYKLFDMDHIDKVKPLIEGLKNGTYHGFNVTIPYKEAVLPFLDIITPKA
QKIGAVNTIYFKDNQVIGDNTDYDGFLYLIKQQSIIKKIMNPIILGSGGAAKSSYAVLKDLGFDSVVVSRNPKDNVHFNH
IISYDKLPSYSYDLVVNTTPIGMHPNINQSPLDESLVHDKFVIDLIYNPLETTLMKYAKHSIGGLDMLIVQAFKAQNIWF
GEEKELKDDILNHIKEDVYE
>Mature_260_residues
MKVFGLIGHPLGHSKSPKLHKIIASYFSRQLVYKLFDMDHIDKVKPLIEGLKNGTYHGFNVTIPYKEAVLPFLDIITPKA
QKIGAVNTIYFKDNQVIGDNTDYDGFLYLIKQQSIIKKIMNPIILGSGGAAKSSYAVLKDLGFDSVVVSRNPKDNVHFNH
IISYDKLPSYSYDLVVNTTPIGMHPNINQSPLDESLVHDKFVIDLIYNPLETTLMKYAKHSIGGLDMLIVQAFKAQNIWF
GEEKELKDDILNHIKEDVYE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=259, Percent_Identity=29.3436293436293, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787983, Length=288, Percent_Identity=28.8194444444444, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=269, Percent_Identity=26.7657992565056, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29424; Mature: 29424

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFGLIGHPLGHSKSPKLHKIIASYFSRQLVYKLFDMDHIDKVKPLIEGLKNGTYHGFN
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEE
VTIPYKEAVLPFLDIITPKAQKIGAVNTIYFKDNQVIGDNTDYDGFLYLIKQQSIIKKIM
EEECHHHHHHHHHHHCCCCHHHCCCEEEEEEECCEEECCCCCCCCEEEEEHHHHHHHHHH
NPIILGSGGAAKSSYAVLKDLGFDSVVVSRNPKDNVHFNHIISYDKLPSYSYDLVVNTTP
HHEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCEEEEEECCC
IGMHPNINQSPLDESLVHDKFVIDLIYNPLETTLMKYAKHSIGGLDMLIVQAFKAQNIWF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GEEKELKDDILNHIKEDVYE
CCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVFGLIGHPLGHSKSPKLHKIIASYFSRQLVYKLFDMDHIDKVKPLIEGLKNGTYHGFN
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEE
VTIPYKEAVLPFLDIITPKAQKIGAVNTIYFKDNQVIGDNTDYDGFLYLIKQQSIIKKIM
EEECHHHHHHHHHHHCCCCHHHCCCEEEEEEECCEEECCCCCCCCEEEEEHHHHHHHHHH
NPIILGSGGAAKSSYAVLKDLGFDSVVVSRNPKDNVHFNHIISYDKLPSYSYDLVVNTTP
HHEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCEEEEEECCC
IGMHPNINQSPLDESLVHDKFVIDLIYNPLETTLMKYAKHSIGGLDMLIVQAFKAQNIWF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
GEEKELKDDILNHIKEDVYE
CCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA