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The map label for this gene is tyrA [H]

Identifier: 162447086

GI number: 162447086

Start: 208406

End: 209239

Strand: Direct

Name: tyrA [H]

Synonym: ACL_0216

Alternate gene names: 162447086

Gene position: 208406-209239 (Clockwise)

Preceding gene: 162447085

Following gene: 162447087

Centisome position: 13.92

GC content: 29.86

Gene sequence:

>834_bases
ATGAAGATATTTATTGTTGGACTTGGTCTTATGGGAGCAAGTTATGCTCAAAAATTAACAAGTGTTGGACACGATGTTTT
TGGGTTTGATAAAGATCATAACACCAACTTAAAAGCGCTTAATGAAGGTGTTATAAAAGGTTATAATTTAAAGGATATGA
AAGATTGTGAACTTGTCATACTTGCTTTATATCCAAATCAAATATTTGAATTTATCAAATCAAATTTATCTTACTTTGAT
ACACAACTAATAACCGATATCAGCGGTACTAAAACTAAACTTCTAGATGAGGTGTTAGAATTACTACCTAAATCAATTAA
TTATGTATCCCATCACCCGATGGCTGGTAGAGAAAAGTCAGGTTATGATCATAAAGATGTAACGATGTTTAAAAATGCTA
ATTTTTTAATCATCGACTCACACCATGCAAAACCACATCACATTGAAACAATTAAAAAACTAGGATTAGATTTAGGATTT
AAAAGGCAAATTGTTTTATCTGCCTATGAACATGATGAACTTATTGCACATACATCCCAGTTAACCCATTTAATTGCAGT
ATCGTTGATGCTTATGAATAAAAATGAACATACAAAAGATGCGACTGGAGATTCATTTAGAGATTTAACAAGAATTGCAA
ATATTAATGAAATCTTATGGACAGAACTCTTTTTAGATAATAAGAACGCTCTTATCCAAAAAATAGATGAATTTGTAGAT
GTTTTAGGTGAACTTAAACATGATATATTAGCCTCAAATGAAGTTATATTGAAAGAAAAGCTTAAAGAATCTAAGAAAAG
GAGAATTAGCTTTGATGAGACAAACACTCGATAA

Upstream 100 bases:

>100_bases
CACTATCTGATGGTGCACAAAGTTTAAAACCACATAAGTTTGAACATATGATGGATCGTCTTGAAAAAGCATCTACAGTA
TTTTCAAAACAACTGAAACG

Downstream 100 bases:

>100_bases
TTATGAAATAGTAGTTAAACAAAATTTGATGAATGATTTGGGTGAGGAAATAACTAGTGTTTATCCTTATAAAGATATTT
TTGTTATTACTGACCATAAT

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKIFIVGLGLMGASYAQKLTSVGHDVFGFDKDHNTNLKALNEGVIKGYNLKDMKDCELVILALYPNQIFEFIKSNLSYFD
TQLITDISGTKTKLLDEVLELLPKSINYVSHHPMAGREKSGYDHKDVTMFKNANFLIIDSHHAKPHHIETIKKLGLDLGF
KRQIVLSAYEHDELIAHTSQLTHLIAVSLMLMNKNEHTKDATGDSFRDLTRIANINEILWTELFLDNKNALIQKIDEFVD
VLGELKHDILASNEVILKEKLKESKKRRISFDETNTR

Sequences:

>Translated_277_residues
MKIFIVGLGLMGASYAQKLTSVGHDVFGFDKDHNTNLKALNEGVIKGYNLKDMKDCELVILALYPNQIFEFIKSNLSYFD
TQLITDISGTKTKLLDEVLELLPKSINYVSHHPMAGREKSGYDHKDVTMFKNANFLIIDSHHAKPHHIETIKKLGLDLGF
KRQIVLSAYEHDELIAHTSQLTHLIAVSLMLMNKNEHTKDATGDSFRDLTRIANINEILWTELFLDNKNALIQKIDEFVD
VLGELKHDILASNEVILKEKLKESKKRRISFDETNTR
>Mature_277_residues
MKIFIVGLGLMGASYAQKLTSVGHDVFGFDKDHNTNLKALNEGVIKGYNLKDMKDCELVILALYPNQIFEFIKSNLSYFD
TQLITDISGTKTKLLDEVLELLPKSINYVSHHPMAGREKSGYDHKDVTMFKNANFLIIDSHHAKPHHIETIKKLGLDLGF
KRQIVLSAYEHDELIAHTSQLTHLIAVSLMLMNKNEHTKDATGDSFRDLTRIANINEILWTELFLDNKNALIQKIDEFVD
VLGELKHDILASNEVILKEKLKESKKRRISFDETNTR

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:
GO:0004665: Prephenate dehydrogenase
GO:0005488: Prephenate dehydrogenase
GO:0006571: Prephenate dehydrogenase
GO:0008977: Prephenate dehydrogenase
GO:0016491: Prephenate dehydrogenase
GO:0016616: Prephenate dehydrogenase
GO:0055114: Prephenate dehydrogenase

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 31605; Mature: 31605

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFIVGLGLMGASYAQKLTSVGHDVFGFDKDHNTNLKALNEGVIKGYNLKDMKDCELVI
CEEEEEECCHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
LALYPNQIFEFIKSNLSYFDTQLITDISGTKTKLLDEVLELLPKSINYVSHHPMAGREKS
EEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GYDHKDVTMFKNANFLIIDSHHAKPHHIETIKKLGLDLGFKRQIVLSAYEHDELIAHTSQ
CCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LTHLIAVSLMLMNKNEHTKDATGDSFRDLTRIANINEILWTELFLDNKNALIQKIDEFVD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLGELKHDILASNEVILKEKLKESKKRRISFDETNTR
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKIFIVGLGLMGASYAQKLTSVGHDVFGFDKDHNTNLKALNEGVIKGYNLKDMKDCELVI
CEEEEEECCHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
LALYPNQIFEFIKSNLSYFDTQLITDISGTKTKLLDEVLELLPKSINYVSHHPMAGREKS
EEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GYDHKDVTMFKNANFLIIDSHHAKPHHIETIKKLGLDLGFKRQIVLSAYEHDELIAHTSQ
CCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LTHLIAVSLMLMNKNEHTKDATGDSFRDLTRIANINEILWTELFLDNKNALIQKIDEFVD
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLGELKHDILASNEVILKEKLKESKKRRISFDETNTR
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]