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The map label for this gene is yabD [H]

Identifier: 162447059

GI number: 162447059

Start: 182630

End: 183388

Strand: Direct

Name: yabD [H]

Synonym: ACL_0189

Alternate gene names: 162447059

Gene position: 182630-183388 (Clockwise)

Preceding gene: 162447058

Following gene: 162447060

Centisome position: 12.2

GC content: 31.23

Gene sequence:

>759_bases
ATGATAGATACCCATGCACATATCAATACAAAAGAATTTGATAAAAGATTAGATGAAGTTTTAATGAACGCCAAATTAAA
TGGTGTGGATAAAATTTTAGTTGTCGGTATGGATACATACCATAACTTACGCGCTATTGAACTAGCTTCTACGTTTGATA
ACCTGTATGCAAGTGTTGGTATACACCCAACAAGTTTAAGTGGAGATGTTGAAGACTTACTTCCACTATTTAAACATAAG
AAAGTAGTTGCTGTTGGAGAAACTGGCATAGACCTTTATTGGGATAAGTCCAATTTAGATGAACAAATAAAGTATTTTAC
AGAACAAATTGAACTGGCCATTTCACTTAACTTGCCAATTATTGTTCATACAAGAAATTCTTTTAATGAAGCCTATGAAT
GTCTTCTACCTTATAAAGGTAAAATTAAAGGTGTATTTCATTCCTTTTCATCAAATATAGAAGATGCAAAAAAAGCAATT
GAACTTGGATTTCTAATTGGTATATCCGGTGTTGTAACCTTTAAAAAGGCTACAGATTTACATGAAATTGTTGAAAAAAT
AGATATATCTCACATGATTTTAGAAACGGATTCACCGTATCTAGCACCTGTACCTTTTAGAGGTAAGATGAATGAACCAG
GTTACACCAAATATGTATTAGAAACTGTTTCAAAAATTAAAAACATGGAAATCCATGAAGTAGATAAAATTACCACTTTA
AATGCAATCAAGTTATTCCAATTGGAGGAAACACTATGA

Upstream 100 bases:

>100_bases
TATACAATATATGTAATTCTTACGAGATTCATACCACAAAACCCCATCTGAAATACTATCTATGATATAATTTACTAGGA
ACAAATAAAAGGATTATTAT

Downstream 100 bases:

>100_bases
AAAAAATATTGAATATCTTATTACTCTTAGTATTAATTTTCACCTTAAGTAGCTGTACAGCACTTGAAGCATATGCAGAT
AATATTAGACCAACTACTTA

Product: TatD family Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MIDTHAHINTKEFDKRLDEVLMNAKLNGVDKILVVGMDTYHNLRAIELASTFDNLYASVGIHPTSLSGDVEDLLPLFKHK
KVVAVGETGIDLYWDKSNLDEQIKYFTEQIELAISLNLPIIVHTRNSFNEAYECLLPYKGKIKGVFHSFSSNIEDAKKAI
ELGFLIGISGVVTFKKATDLHEIVEKIDISHMILETDSPYLAPVPFRGKMNEPGYTKYVLETVSKIKNMEIHEVDKITTL
NAIKLFQLEETL

Sequences:

>Translated_252_residues
MIDTHAHINTKEFDKRLDEVLMNAKLNGVDKILVVGMDTYHNLRAIELASTFDNLYASVGIHPTSLSGDVEDLLPLFKHK
KVVAVGETGIDLYWDKSNLDEQIKYFTEQIELAISLNLPIIVHTRNSFNEAYECLLPYKGKIKGVFHSFSSNIEDAKKAI
ELGFLIGISGVVTFKKATDLHEIVEKIDISHMILETDSPYLAPVPFRGKMNEPGYTKYVLETVSKIKNMEIHEVDKITTL
NAIKLFQLEETL
>Mature_252_residues
MIDTHAHINTKEFDKRLDEVLMNAKLNGVDKILVVGMDTYHNLRAIELASTFDNLYASVGIHPTSLSGDVEDLLPLFKHK
KVVAVGETGIDLYWDKSNLDEQIKYFTEQIELAISLNLPIIVHTRNSFNEAYECLLPYKGKIKGVFHSFSSNIEDAKKAI
ELGFLIGISGVVTFKKATDLHEIVEKIDISHMILETDSPYLAPVPFRGKMNEPGYTKYVLETVSKIKNMEIHEVDKITTL
NAIKLFQLEETL

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=27.7566539923954, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=27.7566539923954, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI226061853, Length=268, Percent_Identity=27.2388059701493, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI226061614, Length=248, Percent_Identity=27.0161290322581, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI14042943, Length=267, Percent_Identity=29.2134831460674, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI225903439, Length=251, Percent_Identity=28.6852589641434, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=225, Percent_Identity=26.2222222222222, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI225903424, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=35.0194552529183, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI87082439, Length=252, Percent_Identity=30.5555555555556, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI48994985, Length=256, Percent_Identity=27.34375, Blast_Score=122, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=28.8256227758007, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=28.5171102661597, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17543026, Length=214, Percent_Identity=29.9065420560748, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17565396, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648690, Length=282, Percent_Identity=26.5957446808511, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24586117, Length=214, Percent_Identity=30.8411214953271, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330018, Length=214, Percent_Identity=30.8411214953271, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 28495; Mature: 28495

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTHAHINTKEFDKRLDEVLMNAKLNGVDKILVVGMDTYHNLRAIELASTFDNLYASVG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCC
IHPTSLSGDVEDLLPLFKHKKVVAVGETGIDLYWDKSNLDEQIKYFTEQIELAISLNLPI
CCCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHEEEEEECCEE
IVHTRNSFNEAYECLLPYKGKIKGVFHSFSSNIEDAKKAIELGFLIGISGVVTFKKATDL
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEHHHCCH
HEIVEKIDISHMILETDSPYLAPVPFRGKMNEPGYTKYVLETVSKIKNMEIHEVDKITTL
HHHHHHHCHHEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHEEEE
NAIKLFQLEETL
CCEEEEEECCCC
>Mature Secondary Structure
MIDTHAHINTKEFDKRLDEVLMNAKLNGVDKILVVGMDTYHNLRAIELASTFDNLYASVG
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCC
IHPTSLSGDVEDLLPLFKHKKVVAVGETGIDLYWDKSNLDEQIKYFTEQIELAISLNLPI
CCCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHEEEEEECCEE
IVHTRNSFNEAYECLLPYKGKIKGVFHSFSSNIEDAKKAIELGFLIGISGVVTFKKATDL
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHEECCCEEEEHHHCCH
HEIVEKIDISHMILETDSPYLAPVPFRGKMNEPGYTKYVLETVSKIKNMEIHEVDKITTL
HHHHHHHCHHEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHEEEE
NAIKLFQLEETL
CCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]