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The map label for this gene is yacO [H]

Identifier: 162447016

GI number: 162447016

Start: 132121

End: 132813

Strand: Direct

Name: yacO [H]

Synonym: ACL_0146

Alternate gene names: 162447016

Gene position: 132121-132813 (Clockwise)

Preceding gene: 162447015

Following gene: 162447017

Centisome position: 8.83

GC content: 33.62

Gene sequence:

>693_bases
ATGATTATTTACGGAAAGAACGTTATTAAAGAAGCAGTTTTGAATAAAAGACCAATCTATAAACTTTATTTAGATGAAAA
ATCTAGCGATAGTAAGTTCATTAATTTTTTAGAAAACAATAATATTAGTTATGAACTAACAAATAAGGGACAATTAAATA
ATTTAACCGACAATGCCGTACACAATGGTGTAGTAGCTGATGTTAAAGATTATCAATACCTAGAATTAGATGTTGTATTG
GATAAAACACGCAGGCAACGCTTTTTAATGCTAGATGAGGTTCAAGATCCACATAACCTAGGAGCTATTTTAAGAAGTGT
TGAAGCAACCAACTATGACGGTGTGATCATTTCCAAGAAACATCAAGTACCACTTACAGGTGTGGTTGCAAAAACATCTT
CTGGAGCGATAGAACACGTTAAGCTGATCTTAGTATCCAACTTGTACCAAACGATTCTTAAACTGCAAAAAGAAGACTTT
TTGGTTGTTGGTACAGCAGGCGAAGCAACTGCAAGCTATAAAGAGATACCAAAGAATCAAAACTTACTGATTATTATGGG
TAATGAAGGCTTTGGGTTAAGACCTTTGATAAAAAAGGGTTGTGACTTATTAGTATCGATTCCAATGCTTGGTAAAGTAA
ACAGTTTAAATGTGAGTGTAGCAACCGCGCTACTCTTATATGAAACAATTTAG

Upstream 100 bases:

>100_bases
ATGGCTAAAGACAGCTGTTAGACGCATTATACATGTCATTTCGGAAATGAAGTAAAGGTGCATTAGATGCACCTTTTTCT
TAAAAGTAAGGAGAAAAAAT

Downstream 100 bases:

>100_bases
GTAAGTGCTATGTATAAGAATGATTATGAACTCATCTACTTATATCGAACGACAAAATCCGAAGAAGTGATTTCCATAAT
CTTTCAAAAATACAAACCAC

Product: TrmH family RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIIYGKNVIKEAVLNKRPIYKLYLDEKSSDSKFINFLENNNISYELTNKGQLNNLTDNAVHNGVVADVKDYQYLELDVVL
DKTRRQRFLMLDEVQDPHNLGAILRSVEATNYDGVIISKKHQVPLTGVVAKTSSGAIEHVKLILVSNLYQTILKLQKEDF
LVVGTAGEATASYKEIPKNQNLLIIMGNEGFGLRPLIKKGCDLLVSIPMLGKVNSLNVSVATALLLYETI

Sequences:

>Translated_230_residues
MIIYGKNVIKEAVLNKRPIYKLYLDEKSSDSKFINFLENNNISYELTNKGQLNNLTDNAVHNGVVADVKDYQYLELDVVL
DKTRRQRFLMLDEVQDPHNLGAILRSVEATNYDGVIISKKHQVPLTGVVAKTSSGAIEHVKLILVSNLYQTILKLQKEDF
LVVGTAGEATASYKEIPKNQNLLIIMGNEGFGLRPLIKKGCDLLVSIPMLGKVNSLNVSVATALLLYETI
>Mature_230_residues
MIIYGKNVIKEAVLNKRPIYKLYLDEKSSDSKFINFLENNNISYELTNKGQLNNLTDNAVHNGVVADVKDYQYLELDVVL
DKTRRQRFLMLDEVQDPHNLGAILRSVEATNYDGVIISKKHQVPLTGVVAKTSSGAIEHVKLILVSNLYQTILKLQKEDF
LVVGTAGEATASYKEIPKNQNLLIIMGNEGFGLRPLIKKGCDLLVSIPMLGKVNSLNVSVATALLLYETI

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=216, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1790623, Length=237, Percent_Identity=40.084388185654, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1788935, Length=232, Percent_Identity=25.4310344827586, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=247, Percent_Identity=27.1255060728745, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324775, Length=284, Percent_Identity=30.2816901408451, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 25633; Mature: 25633

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIYGKNVIKEAVLNKRPIYKLYLDEKSSDSKFINFLENNNISYELTNKGQLNNLTDNAV
CEEECHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHH
HNGVVADVKDYQYLELDVVLDKTRRQRFLMLDEVQDPHNLGAILRSVEATNYDGVIISKK
CCCEEECCCCCEEEEEEEEECCHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECC
HQVPLTGVVAKTSSGAIEHVKLILVSNLYQTILKLQKEDFLVVGTAGEATASYKEIPKNQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCC
NLLIIMGNEGFGLRPLIKKGCDLLVSIPMLGKVNSLNVSVATALLLYETI
CEEEEECCCCCCCCHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MIIYGKNVIKEAVLNKRPIYKLYLDEKSSDSKFINFLENNNISYELTNKGQLNNLTDNAV
CEEECHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHH
HNGVVADVKDYQYLELDVVLDKTRRQRFLMLDEVQDPHNLGAILRSVEATNYDGVIISKK
CCCEEECCCCCEEEEEEEEECCHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCCEEEECC
HQVPLTGVVAKTSSGAIEHVKLILVSNLYQTILKLQKEDFLVVGTAGEATASYKEIPKNQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHCCCCC
NLLIIMGNEGFGLRPLIKKGCDLLVSIPMLGKVNSLNVSVATALLLYETI
CEEEEECCCCCCCCHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]