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The map label for this gene is lacF [H]

Identifier: 162446923

GI number: 162446923

Start: 43497

End: 44456

Strand: Direct

Name: lacF [H]

Synonym: ACL_0037

Alternate gene names: 162446923

Gene position: 43497-44456 (Clockwise)

Preceding gene: 162446922

Following gene: 162446924

Centisome position: 2.91

GC content: 31.77

Gene sequence:

>960_bases
ATGTCTAAAAAGCGAAATAAAATTAATTACAACAAATGGGGATATTATTTTGTAGCACCTTTTATCATTGTATATTTGGT
CTTTTCTCTGATCCCGCTATTATCAACGTTTTACTATAGTTTCTTTGAATATTACTATGCACAAGGTGGGTTTATAAAGA
TAGGACCAAATTTCATAGGCTTTGAAAATTATGTAACATTGTTTAGCCAAGGTGTCTTCATAAAATATCTGGGTAATACA
ATTGTTTTATGGTTGATGGGTTTTATACCCCAAGTTATTGTTTCATTACTGATGGCATTATGGTTTACATCCTTTAGACT
TAAACTAAAAGGTACGGCATTTTTTAAAACAGTCATGTATCTTCCAAACCTAGTGATGGCAGCAGCCTTTTCCATGTTAT
TTGTTCAACTATTTTCAAATACAGGTGGGTTAACAACATTACTAATTGAATTAAACATTATCCCCGAAACATTTAGTTTC
GTTGATAATGTTTGGCCAACAAGAGCGCTAATAGCACTGATGAACTTCTTGATGTGGTTTGGTAATACAACGATATTACT
CATGGCAGGTATTATGGGTATTGATGATTCTTTAATTGAATCTGCCAGTGTAGATGGTGCAAATAGTAGACAAGTATTTA
CTAAGATTACACTACCACTTTTAAAACCTATATTATTATTTGTTTTAGTTACTTCTTTAGTTGGTGGTATTCAAATGTTT
GATATACCATTTGTCTTTACAAGAGGGACTGGTGGTCCACAAGGATCATCACAGACTGTTATGATGTACATTAGTGGCTT
ACTAAGAACAAGTAAGCAATATGATATGGCAGGTACTGCTTCTGTTATATTATTTATTCTTACAACGATTATTAGCTTAT
TATTCTTCTTTATCATGAATAAAGATGAAATTAAAGAATACCGTGAAGAGAAGAGAATAAGAAAGGAGATGAAAAGATGA

Upstream 100 bases:

>100_bases
ATGAGGGAATTACCTTCCCTCATCAAGTCTTTTTGAATCAATAACTTTTAAAATTATGTAAACTTATTTTTAAATATAAG
TACATGAAGGGGTATAATTT

Downstream 100 bases:

>100_bases
ACAAATCATTTAATTTAAAAAAGATGCGTTTTGTTGATAAGCTCCCTTTATATTTTCTTAAATTCTTTATCTACTTTATT
TTAGGTGTGTTTGCATTTGT

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSKKRNKINYNKWGYYFVAPFIIVYLVFSLIPLLSTFYYSFFEYYYAQGGFIKIGPNFIGFENYVTLFSQGVFIKYLGNT
IVLWLMGFIPQVIVSLLMALWFTSFRLKLKGTAFFKTVMYLPNLVMAAAFSMLFVQLFSNTGGLTTLLIELNIIPETFSF
VDNVWPTRALIALMNFLMWFGNTTILLMAGIMGIDDSLIESASVDGANSRQVFTKITLPLLKPILLFVLVTSLVGGIQMF
DIPFVFTRGTGGPQGSSQTVMMYISGLLRTSKQYDMAGTASVILFILTTIISLLFFFIMNKDEIKEYREEKRIRKEMKR

Sequences:

>Translated_319_residues
MSKKRNKINYNKWGYYFVAPFIIVYLVFSLIPLLSTFYYSFFEYYYAQGGFIKIGPNFIGFENYVTLFSQGVFIKYLGNT
IVLWLMGFIPQVIVSLLMALWFTSFRLKLKGTAFFKTVMYLPNLVMAAAFSMLFVQLFSNTGGLTTLLIELNIIPETFSF
VDNVWPTRALIALMNFLMWFGNTTILLMAGIMGIDDSLIESASVDGANSRQVFTKITLPLLKPILLFVLVTSLVGGIQMF
DIPFVFTRGTGGPQGSSQTVMMYISGLLRTSKQYDMAGTASVILFILTTIISLLFFFIMNKDEIKEYREEKRIRKEMKR
>Mature_318_residues
SKKRNKINYNKWGYYFVAPFIIVYLVFSLIPLLSTFYYSFFEYYYAQGGFIKIGPNFIGFENYVTLFSQGVFIKYLGNTI
VLWLMGFIPQVIVSLLMALWFTSFRLKLKGTAFFKTVMYLPNLVMAAAFSMLFVQLFSNTGGLTTLLIELNIIPETFSFV
DNVWPTRALIALMNFLMWFGNTTILLMAGIMGIDDSLIESASVDGANSRQVFTKITLPLLKPILLFVLVTSLVGGIQMFD
IPFVFTRGTGGPQGSSQTVMMYISGLLRTSKQYDMAGTASVILFILTTIISLLFFFIMNKDEIKEYREEKRIRKEMKR

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789861, Length=300, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36440; Mature: 36309

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKRNKINYNKWGYYFVAPFIIVYLVFSLIPLLSTFYYSFFEYYYAQGGFIKIGPNFIG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
FENYVTLFSQGVFIKYLGNTIVLWLMGFIPQVIVSLLMALWFTSFRLKLKGTAFFKTVMY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHH
LPNLVMAAAFSMLFVQLFSNTGGLTTLLIELNIIPETFSFVDNVWPTRALIALMNFLMWF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHH
GNTTILLMAGIMGIDDSLIESASVDGANSRQVFTKITLPLLKPILLFVLVTSLVGGIQMF
CCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DIPFVFTRGTGGPQGSSQTVMMYISGLLRTSKQYDMAGTASVILFILTTIISLLFFFIMN
ECCEEEECCCCCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
KDEIKEYREEKRIRKEMKR
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKKRNKINYNKWGYYFVAPFIIVYLVFSLIPLLSTFYYSFFEYYYAQGGFIKIGPNFIG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
FENYVTLFSQGVFIKYLGNTIVLWLMGFIPQVIVSLLMALWFTSFRLKLKGTAFFKTVMY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHH
LPNLVMAAAFSMLFVQLFSNTGGLTTLLIELNIIPETFSFVDNVWPTRALIALMNFLMWF
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHH
GNTTILLMAGIMGIDDSLIESASVDGANSRQVFTKITLPLLKPILLFVLVTSLVGGIQMF
CCHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DIPFVFTRGTGGPQGSSQTVMMYISGLLRTSKQYDMAGTASVILFILTTIISLLFFFIMN
ECCEEEECCCCCCCCCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
KDEIKEYREEKRIRKEMKR
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]