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The map label for this gene is qorA [H]

Identifier: 162420812

GI number: 162420812

Start: 768888

End: 769661

Strand: Direct

Name: qorA [H]

Synonym: YpAngola_A0756

Alternate gene names: 162420812

Gene position: 768888-769661 (Clockwise)

Preceding gene: 162418877

Following gene: 162418369

Centisome position: 17.07

GC content: 53.88

Gene sequence:

>774_bases
ATGGCAAAGCATATTCAATTTACCACCACGGGTGGACCAGATGTATTGCAATATCTTGAATTCACCCCCTCAGACCCCGC
CCCCCATGAAGTCCAGGTCGAAAATAAAGCTATCGGTATCAATTATATCGATACTTATGTCCGCAGCGGGCTTTATCCTC
CTGCCCATTTGCCCAGTGGTTTAGGTACAGAAGCGGCCGGTATCGTCAGTAAAGTGGGGGCTGCGGTCAGTTCCGTGAAG
GTCGGTGATCGGGTGGTGTATGCCCAATCCGCTCTCGGTGCTTACAGCGAAGTGCATAATGTTCCAGCGGATAAAATCGC
CTTACTGCCGGAGCAGATCTCTTTTGAACAAGCGGCAGCCTCGTTTTTGAAAGGGCTGACTGCCTATTATTTGTTGCGCC
AGACCCACGAGATTAAACCGGGGGAAGTGTTCCTGTTCCACGCTGCGGCGGGAGGGGTTGGGCTGATTGCCTGCCAATGG
GCCAAAGCACTGGGTGCCAAATTGATCGGCACGGTGGGATCCGATGAGAAAGCCCAGTTGGCCAAAGCGGCCGGGGCTTG
GGCGACCATCAACTATCGGACAGAAAATATTGCTCAGCGGGTGGCCGAGCTAACCGAGGGTGAGAAAGTAGGCGTCGTGT
ATGACTCGGTTGGGAAAAGCACTTGGGAAGCCTCGCTTGATAGTTTAAAGCGCCGGGGCCTGCTGGTTAGCTTTGGTAAT
GCCTCTGGGCCGGTAACGGGTGTCAACTGTACGCAGTACTCGCGTAATCGATAG

Upstream 100 bases:

>100_bases
CGCACAAATCCCGATAAGCTGATATCCGTCAGTGAGTCAGGTGAGTGAACAGAGCGCCCTTGTAACCTCAAGTAAGAAGG
CTATACCTCGAGGAACTGAC

Downstream 100 bases:

>100_bases
TTACCGACGATATCAAAACGGTAATCCGCAAAGTTATATTTGGAGAATACCTGTTCGATAATATCGATAATATTCAGGTC
CTGAAATATCCGGCAGTTGC

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVK
VGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
ASGPVTGVNCTQYSRNR

Sequences:

>Translated_257_residues
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVK
VGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
ASGPVTGVNCTQYSRNR
>Mature_256_residues
AKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVKV
GDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWA
KALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGNA
SGPVTGVNCTQYSRNR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=242, Percent_Identity=30.9917355371901, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI13236495, Length=242, Percent_Identity=30.9917355371901, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=34.9753694581281, Blast_Score=121, Evalue=6e-28,
Organism=Homo sapiens, GI22538446, Length=241, Percent_Identity=32.3651452282158, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI22538444, Length=241, Percent_Identity=32.3651452282158, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI18379349, Length=210, Percent_Identity=34.2857142857143, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI28557745, Length=224, Percent_Identity=33.0357142857143, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI24308257, Length=246, Percent_Identity=28.4552845528455, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI47519420, Length=244, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=249, Percent_Identity=75.1004016064257, Blast_Score=387, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17507255, Length=245, Percent_Identity=33.0612244897959, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17536829, Length=174, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=256, Percent_Identity=39.453125, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323961, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550423, Length=257, Percent_Identity=28.4046692607004, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 27221; Mature: 27090

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSG
CCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCCEECHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGAAVSSVKVGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAA
CCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHH
SFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWAKALGAKLIGTVGSDEKAQL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
AKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVNCTQYSRNR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSG
CCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCCEECHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGAAVSSVKVGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAA
CCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHH
SFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWAKALGAKLIGTVGSDEKAQL
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
AKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVNCTQYSRNR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]