Click here to switch to the map view.

The map label for this gene is ydhC [H]

Identifier: 162329622

GI number: 162329622

Start: 2682459

End: 2683661

Strand: Reverse

Name: ydhC [H]

Synonym: VC0395_A2531

Alternate gene names: 162329622

Gene position: 2683661-2682459 (Counterclockwise)

Preceding gene: 147674109

Following gene: 147674633

Centisome position: 88.74

GC content: 50.46

Gene sequence:

>1203_bases
ATGAAAGTATCTTTCTTCCAGTTGGTTTACCTTTCGGCACTCTCCATGCTCGGTTTTATTGCCACCGACATGTATCTGCC
TGCGTTTAAAATGATGGAAACCGCTTTTGCGACCGGCCCTGAACAAATCGCTCTATCACTGACGGTGTTCTTAGTGGGGA
TGGCGCTTGGCCAGTTACTGTGGGGCTTAGCTTCCGACAAATTTGGCCATCGTAATACGCTGATTGCTGGCTTACTCGTT
TTTACCCTCGCCTCTGCCGGACTCGCGTTTAGCTCAACGGTATGGCAACTGCTACTGCTGCGTTTTATCCAAGCGATTGG
GGTGTGCGCGCCTGCGGTCATTTGGCAGGCGATGGTGATCAAGCGTTACCCAAGCTCAGCCAGCCAACAGCTGTTTGCGA
CCATCATGCCACTGGTAGCGCTCTCTCCAGCCCTAGCACCGCAACTGGGTGTACTGCTGGCAGATTACTTTGGCTGGCAC
AGCATCTTTTTGACTTTAACCTTGATGGGTATTGTGTTGGTGGTGAGTACGGGCTTACAAACCAATGAAATTGCTGAGCC
AAAAACCACTTCTATCGCGCAAGATATTAAAGGTTTACTGAAAAGCAAAACCTATCTCGGCAATGTGATGATGTTTGCTT
GTGCATCGGCGGCGTTTTTTGCCTACCTGACCGGGATGCCGGAAATCATGGCGCAGCTTGGTTATCAAGCACGGGACATT
GGCCTGAGCTTTATTCCACAAACCATTGCATTTATGGTGGGTGGCTACCTAGGTAAGAAAGCGGTTCAGAAATACGGTGA
TGAACTGGTGCTCAAACAGTTGATTGCGCTGTTTACCCTGTCAGCGGCGATGATTTTTGTCGCCTCACAATGGACGCTCA
GCTCAATTTGGCCAATCTTGGCTCCATTCTGCTTGATTGCGGTGGCCAATGGTGCCATGTATCCGATAGTGGTCAACCGT
GCTTTATCCAGTGCTAAGCAAAGCCCAGCAACCGCTGCCGGATTACAAAACAGCTTACAGATCAGTGTCAGCAGTTTATC
CAGCGCCCTAGTGGCTGCGCTTGCCAGCCAAGCTCAGCCAGTGACAGGCATTGCGATTGTGTTGTGTACAGGCGGGTTGT
GGATAGGTTACATACTCTCTAACCGTCAGTTACGTGAACAGTTCACCACCCCCGACAATGCTCGCGTGGTCAGTGACGAA
TAA

Upstream 100 bases:

>100_bases
ATCACAAGACAAAACTAGAATGTAACTACAGAAAAATCCTGGTTGGCGCCAACGGATACTGAAAAAAACATGTGTGAATA
ATTTTGATGGACATGAAAAA

Downstream 100 bases:

>100_bases
ACTGTACTTGAGTAATACAAAAAGAGCCGCGAATGCGGCTCTTTTTTCAATCGGTTCAATTATTTCTTTTTCGCCGGACG
CTGCCAGCCAGCAATTTTGC

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKVSFFQLVYLSALSMLGFIATDMYLPAFKMMETAFATGPEQIALSLTVFLVGMALGQLLWGLASDKFGHRNTLIAGLLV
FTLASAGLAFSSTVWQLLLLRFIQAIGVCAPAVIWQAMVIKRYPSSASQQLFATIMPLVALSPALAPQLGVLLADYFGWH
SIFLTLTLMGIVLVVSTGLQTNEIAEPKTTSIAQDIKGLLKSKTYLGNVMMFACASAAFFAYLTGMPEIMAQLGYQARDI
GLSFIPQTIAFMVGGYLGKKAVQKYGDELVLKQLIALFTLSAAMIFVASQWTLSSIWPILAPFCLIAVANGAMYPIVVNR
ALSSAKQSPATAAGLQNSLQISVSSLSSALVAALASQAQPVTGIAIVLCTGGLWIGYILSNRQLREQFTTPDNARVVSDE

Sequences:

>Translated_400_residues
MKVSFFQLVYLSALSMLGFIATDMYLPAFKMMETAFATGPEQIALSLTVFLVGMALGQLLWGLASDKFGHRNTLIAGLLV
FTLASAGLAFSSTVWQLLLLRFIQAIGVCAPAVIWQAMVIKRYPSSASQQLFATIMPLVALSPALAPQLGVLLADYFGWH
SIFLTLTLMGIVLVVSTGLQTNEIAEPKTTSIAQDIKGLLKSKTYLGNVMMFACASAAFFAYLTGMPEIMAQLGYQARDI
GLSFIPQTIAFMVGGYLGKKAVQKYGDELVLKQLIALFTLSAAMIFVASQWTLSSIWPILAPFCLIAVANGAMYPIVVNR
ALSSAKQSPATAAGLQNSLQISVSSLSSALVAALASQAQPVTGIAIVLCTGGLWIGYILSNRQLREQFTTPDNARVVSDE
>Mature_400_residues
MKVSFFQLVYLSALSMLGFIATDMYLPAFKMMETAFATGPEQIALSLTVFLVGMALGQLLWGLASDKFGHRNTLIAGLLV
FTLASAGLAFSSTVWQLLLLRFIQAIGVCAPAVIWQAMVIKRYPSSASQQLFATIMPLVALSPALAPQLGVLLADYFGWH
SIFLTLTLMGIVLVVSTGLQTNEIAEPKTTSIAQDIKGLLKSKTYLGNVMMFACASAAFFAYLTGMPEIMAQLGYQARDI
GLSFIPQTIAFMVGGYLGKKAVQKYGDELVLKQLIALFTLSAAMIFVASQWTLSSIWPILAPFCLIAVANGAMYPIVVNR
ALSSAKQSPATAAGLQNSLQISVSSLSSALVAALASQAQPVTGIAIVLCTGGLWIGYILSNRQLREQFTTPDNARVVSDE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=395, Percent_Identity=43.2911392405063, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788509, Length=270, Percent_Identity=25.5555555555556, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790794, Length=194, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790146, Length=217, Percent_Identity=23.963133640553, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324264, Length=159, Percent_Identity=26.4150943396226, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42811; Mature: 42811

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHCCHHHHHHHCCHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure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CHHHHHHHHHCCHHHHHHHCCHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]