Click here to switch to the map view.

The map label for this gene is pdxH [H]

Identifier: 162149002

GI number: 162149002

Start: 3323527

End: 3324129

Strand: Direct

Name: pdxH [H]

Synonym: GDI_3232

Alternate gene names: 162149002

Gene position: 3323527-3324129 (Clockwise)

Preceding gene: 162148999

Following gene: 162149003

Centisome position: 84.26

GC content: 69.15

Gene sequence:

>603_bases
CTGGGGCCGCTGATCGATCTGGGCGCGGACCCCTTCGCCCTGTTCGCGGCATGGATGCGCGACGCCGAGGCCGCGGAACC
GGTCGATCCCAACGCGATGGCCCTGGCCACCGCCACGCCGGACGGCCGCCCCTCGGTGCGGATGATCCTGCTGAAGGGCG
CGGACCGGCGGGGCTTCGTCTTCTATACCAACCTCGAAAGCCGCAAGGCCGGGGAACTGACGGAAAACCCGCACGCCGCG
TTGCTGTTCCACTGGAAGAGCGTGGCGCGCCAGATCCGCATCGAGGGATCGGTCGAACGCGTCAGCGACGCCGAGGCCGA
TGCCTATTTCGCCAGCCGTTCGCGCATGTCCCGACTGGGCGCCATCGCATCCGACCAGTCGCGCCCCCTGCCCGACCGCG
CGATCTTCGAACATCGCCTGGCGGACCTGGAAGAGCGCTACCCCGACGGGGACGGCGCCATTCCGCGCCCGGCGAACTGG
TCGGGTTTCCGGCTGGTTCCGGACCGAATCGAGTTCTGGCAGAACCGCCCGCATCGGTTGCATGATCGGGCCGTCTGGCG
CCGCGCCGAAACGGGATGGGAGACGACGCGTCTCTATCCCTAG

Upstream 100 bases:

>100_bases
CGCGGGCATCGTGGCAAGCGGGCCAGGCAGGAATGGAACGGATGGCATGACGACCCCGCACGGCGACCCTGGGCAAAGCG
ACCTCGGCCCGCAGGCCCAT

Downstream 100 bases:

>100_bases
TTGGGCCCTGGTTGGGCGGGAGAGACGGCCCGATCCTCGCGAATTGCACCATCGAACGGCGACGTTCTTCGGAGTCTGGA
GAAAAGAATTTGAAAAACAT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MGPLIDLGADPFALFAAWMRDAEAAEPVDPNAMALATATPDGRPSVRMILLKGADRRGFVFYTNLESRKAGELTENPHAA
LLFHWKSVARQIRIEGSVERVSDAEADAYFASRSRMSRLGAIASDQSRPLPDRAIFEHRLADLEERYPDGDGAIPRPANW
SGFRLVPDRIEFWQNRPHRLHDRAVWRRAETGWETTRLYP

Sequences:

>Translated_200_residues
MGPLIDLGADPFALFAAWMRDAEAAEPVDPNAMALATATPDGRPSVRMILLKGADRRGFVFYTNLESRKAGELTENPHAA
LLFHWKSVARQIRIEGSVERVSDAEADAYFASRSRMSRLGAIASDQSRPLPDRAIFEHRLADLEERYPDGDGAIPRPANW
SGFRLVPDRIEFWQNRPHRLHDRAVWRRAETGWETTRLYP
>Mature_199_residues
GPLIDLGADPFALFAAWMRDAEAAEPVDPNAMALATATPDGRPSVRMILLKGADRRGFVFYTNLESRKAGELTENPHAAL
LFHWKSVARQIRIEGSVERVSDAEADAYFASRSRMSRLGAIASDQSRPLPDRAIFEHRLADLEERYPDGDGAIPRPANWS
GFRLVPDRIEFWQNRPHRLHDRAVWRRAETGWETTRLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=181, Percent_Identity=46.4088397790055, Blast_Score=177, Evalue=5e-45,
Organism=Escherichia coli, GI1787926, Length=195, Percent_Identity=43.5897435897436, Blast_Score=173, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17553712, Length=196, Percent_Identity=44.8979591836735, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6319509, Length=199, Percent_Identity=42.2110552763819, Blast_Score=147, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24644901, Length=208, Percent_Identity=40.3846153846154, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI45551845, Length=208, Percent_Identity=40.3846153846154, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24644903, Length=171, Percent_Identity=30.9941520467836, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22652; Mature: 22521

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLIDLGADPFALFAAWMRDAEAAEPVDPNAMALATATPDGRPSVRMILLKGADRRGFV
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCEE
FYTNLESRKAGELTENPHAALLFHWKSVARQIRIEGSVERVSDAEADAYFASRSRMSRLG
EEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
AIASDQSRPLPDRAIFEHRLADLEERYPDGDGAIPRPANWSGFRLVPDRIEFWQNRPHRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHCCCCCHH
HDRAVWRRAETGWETTRLYP
HHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure 
GPLIDLGADPFALFAAWMRDAEAAEPVDPNAMALATATPDGRPSVRMILLKGADRRGFV
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCEE
FYTNLESRKAGELTENPHAALLFHWKSVARQIRIEGSVERVSDAEADAYFASRSRMSRLG
EEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHH
AIASDQSRPLPDRAIFEHRLADLEERYPDGDGAIPRPANWSGFRLVPDRIEFWQNRPHRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHCCCCCHH
HDRAVWRRAETGWETTRLYP
HHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA