Click here to switch to the map view.

The map label for this gene is ydjJ [C]

Identifier: 162148912

GI number: 162148912

Start: 3231549

End: 3232589

Strand: Direct

Name: ydjJ [C]

Synonym: GDI_3142

Alternate gene names: 162148912

Gene position: 3231549-3232589 (Clockwise)

Preceding gene: 162148911

Following gene: 162148913

Centisome position: 81.93

GC content: 66.19

Gene sequence:

>1041_bases
ATGCCCGTTGCCCTCGTCCTCGAACGCAAGGACGTCCTGTCCTTGCGCGACATCGACATTCCCCAGACGCTGGGTCCCCG
CGACGTCAGAGTGAAAATCGACACTGTCGGCATCTGCGGCAGCGACGTGCATTATTATACCCATGGCCGGATCGGCCACT
TCGTGGTCGAGAAACCGATGGTGCTGGGCCACGAGGCATCGGGCACCGTGGTCGAGCTCGGCACGGCCGTCACGAACCTG
AAAGTCGGCGACCGGGTCTGCATGGAACCGGGTATCCCCGATCCCACCTCGCGCGCATCGAAGCTCGGCATCTACAATGT
CGATCCCGCCGTCTCGTTCTGGGCGACGCCGCCGGTGCATGGCTGCCTCACCCCTCTGGTGGTGCATCCCGCCGCCTTCA
CCTATCGCCTGCCGGACACCGTCAGCTTTGCCGAAGGCGCCATGGTCGAACCGTTTGCGATCGGCGTGCAGGCGGCCGTG
AAGGCGAAGATCAAGCCTGGCGATACCTGTGTGGTGACCGGATGCGGGCCGATCGGAATCATGGTGGCGCTGGCGGCCCT
CGGCGCGGGCGCGGGCAAGGTCATCGTGTCGGACATCGCCGCGCCGAAGCTGGACATCGCGGGCCGGTATGCCGGCATCA
TCCCGGTCGATGTCGCGCGGGATTCGCTGCGCGACGCCGTGCGGGCGGAATGCGGCGAGGGCTGGGGCGCGGACGTGGTG
TTCGAGGCCAGCGGCAGCCCGCGCGTCTATGACGATGCGCTGGCCGTCGTGCGGCCCGGCGGCACGCTGGTGCTGGTGGG
CATGCCGGTCGACAAGGTGTCGTTCGATATCGTTGCCGCCCAGGCCAAGGAAATTACGATCGAGACCGTATTCCGCTACG
CCAATGTCTACGACCGGGCGATCGCGCTGATTGCTTCCGGCAAGGTCGATCTCAAGCCGCTGATCTCGGGAACCTACAAC
TTCGCGGATGCGGTCGAGGCATTCGAACGGGCGGCGTCCGCCCGGCCCGGGGACGTCAAGTTGCAGATCCGCATGGCGTA
G

Upstream 100 bases:

>100_bases
GAAAACGACCTAGACGCCCCCGCGGGGGCCCGTCATAGAATCCGGGCAACGAACGACAAGCGGCCCCGATAGATCCATCG
AGAGGCCGCGGGAGGAAAAA

Downstream 100 bases:

>100_bases
GGCCGCCAACGAAACACGTCCCCCGCTCCAGGGAGAAGAACGGAAGAATGGTCCACGGCACTCATTCCGCCCGGAAGGCG
CGCGCCGCGACACCCGTCTT

Product: D-xylulose reductase

Products: NA

Alternate protein names: Xylitol dehydrogenase; XDH [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MPVALVLERKDVLSLRDIDIPQTLGPRDVRVKIDTVGICGSDVHYYTHGRIGHFVVEKPMVLGHEASGTVVELGTAVTNL
KVGDRVCMEPGIPDPTSRASKLGIYNVDPAVSFWATPPVHGCLTPLVVHPAAFTYRLPDTVSFAEGAMVEPFAIGVQAAV
KAKIKPGDTCVVTGCGPIGIMVALAALGAGAGKVIVSDIAAPKLDIAGRYAGIIPVDVARDSLRDAVRAECGEGWGADVV
FEASGSPRVYDDALAVVRPGGTLVLVGMPVDKVSFDIVAAQAKEITIETVFRYANVYDRAIALIASGKVDLKPLISGTYN
FADAVEAFERAASARPGDVKLQIRMA

Sequences:

>Translated_346_residues
MPVALVLERKDVLSLRDIDIPQTLGPRDVRVKIDTVGICGSDVHYYTHGRIGHFVVEKPMVLGHEASGTVVELGTAVTNL
KVGDRVCMEPGIPDPTSRASKLGIYNVDPAVSFWATPPVHGCLTPLVVHPAAFTYRLPDTVSFAEGAMVEPFAIGVQAAV
KAKIKPGDTCVVTGCGPIGIMVALAALGAGAGKVIVSDIAAPKLDIAGRYAGIIPVDVARDSLRDAVRAECGEGWGADVV
FEASGSPRVYDDALAVVRPGGTLVLVGMPVDKVSFDIVAAQAKEITIETVFRYANVYDRAIALIASGKVDLKPLISGTYN
FADAVEAFERAASARPGDVKLQIRMA
>Mature_345_residues
PVALVLERKDVLSLRDIDIPQTLGPRDVRVKIDTVGICGSDVHYYTHGRIGHFVVEKPMVLGHEASGTVVELGTAVTNLK
VGDRVCMEPGIPDPTSRASKLGIYNVDPAVSFWATPPVHGCLTPLVVHPAAFTYRLPDTVSFAEGAMVEPFAIGVQAAVK
AKIKPGDTCVVTGCGPIGIMVALAALGAGAGKVIVSDIAAPKLDIAGRYAGIIPVDVARDSLRDAVRAECGEGWGADVVF
EASGSPRVYDDALAVVRPGGTLVLVGMPVDKVSFDIVAAQAKEITIETVFRYANVYDRAIALIASGKVDLKPLISGTYNF
ADAVEAFERAASARPGDVKLQIRMA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=328, Percent_Identity=40.2439024390244, Blast_Score=258, Evalue=5e-69,
Organism=Escherichia coli, GI1788073, Length=327, Percent_Identity=37.6146788990826, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790045, Length=339, Percent_Identity=31.2684365781711, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1790718, Length=317, Percent_Identity=29.9684542586751, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI226510992, Length=336, Percent_Identity=31.25, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787863, Length=334, Percent_Identity=26.9461077844311, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788075, Length=337, Percent_Identity=28.486646884273, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788407, Length=347, Percent_Identity=27.0893371757925, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87082125, Length=350, Percent_Identity=25.1428571428571, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=335, Percent_Identity=42.089552238806, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17562878, Length=318, Percent_Identity=42.4528301886792, Blast_Score=247, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6323099, Length=349, Percent_Identity=44.1260744985673, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6319955, Length=334, Percent_Identity=41.3173652694611, Blast_Score=239, Evalue=6e-64,
Organism=Saccharomyces cerevisiae, GI6322619, Length=334, Percent_Identity=41.3173652694611, Blast_Score=238, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6319257, Length=338, Percent_Identity=26.6272189349112, Blast_Score=115, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319258, Length=376, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737897, Length=342, Percent_Identity=39.4736842105263, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=38.3040935672515, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI45551930, Length=308, Percent_Identity=30.8441558441558, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI45550770, Length=308, Percent_Identity=30.8441558441558, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221457811, Length=308, Percent_Identity=30.8441558441558, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.9 [H]

Molecular weight: Translated: 36368; Mature: 36237

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVALVLERKDVLSLRDIDIPQTLGPRDVRVKIDTVGICGSDVHYYTHGRIGHFVVEKPM
CCEEEEEECCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCEEEEEEECCE
VLGHEASGTVVELGTAVTNLKVGDRVCMEPGIPDPTSRASKLGIYNVDPAVSFWATPPVH
EECCCCCCCEEEECCCEEEEECCCEEEECCCCCCCCCHHHHCCEEECCCCEEEECCCCHH
GCLTPLVVHPAAFTYRLPDTVSFAEGAMVEPFAIGVQAAVKAKIKPGDTCVVTGCGPIGI
HHHHHHHCCCCEEEEECCCCCCCCCCCEECHHHHCEEEEEEEECCCCCEEEEECCCHHHH
MVALAALGAGAGKVIVSDIAAPKLDIAGRYAGIIPVDVARDSLRDAVRAECGEGWGADVV
HHHHHHHCCCCCEEEEECCCCCCEEECCCEECEEEHHHHHHHHHHHHHHHHCCCCCCCEE
FEASGSPRVYDDALAVVRPGGTLVLVGMPVDKVSFDIVAAQAKEITIETVFRYANVYDRA
EECCCCCCEECCEEEEECCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
IALIASGKVDLKPLISGTYNFADAVEAFERAASARPGDVKLQIRMA
EEEEECCCCCEEHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure 
PVALVLERKDVLSLRDIDIPQTLGPRDVRVKIDTVGICGSDVHYYTHGRIGHFVVEKPM
CEEEEEECCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCEEEEEEECCE
VLGHEASGTVVELGTAVTNLKVGDRVCMEPGIPDPTSRASKLGIYNVDPAVSFWATPPVH
EECCCCCCCEEEECCCEEEEECCCEEEECCCCCCCCCHHHHCCEEECCCCEEEECCCCHH
GCLTPLVVHPAAFTYRLPDTVSFAEGAMVEPFAIGVQAAVKAKIKPGDTCVVTGCGPIGI
HHHHHHHCCCCEEEEECCCCCCCCCCCEECHHHHCEEEEEEEECCCCCEEEEECCCHHHH
MVALAALGAGAGKVIVSDIAAPKLDIAGRYAGIIPVDVARDSLRDAVRAECGEGWGADVV
HHHHHHHCCCCCEEEEECCCCCCEEECCCEECEEEHHHHHHHHHHHHHHHHCCCCCCCEE
FEASGSPRVYDDALAVVRPGGTLVLVGMPVDKVSFDIVAAQAKEITIETVFRYANVYDRA
EECCCCCCEECCEEEEECCCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHH
IALIASGKVDLKPLISGTYNFADAVEAFERAASARPGDVKLQIRMA
EEEEECCCCCEEHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]