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The map label for this gene is fabH [H]

Identifier: 162148846

GI number: 162148846

Start: 3172568

End: 3173593

Strand: Reverse

Name: fabH [H]

Synonym: GDI_3075

Alternate gene names: 162148846

Gene position: 3173593-3172568 (Counterclockwise)

Preceding gene: 162148847

Following gene: 162148845

Centisome position: 80.46

GC content: 67.93

Gene sequence:

>1026_bases
GTGCGGCGGGTCGGGTCCGGCGCCGGGTTTGGAATGATGGGAATGATGGCGAGACGTTCGCTTCTGGTCGGGTTTGGCGG
ATATCTGCCGGACCGGATCGTGACCAATGACGAACTGGCGGCGCGCCTGGAGACGTCGGACGAGTGGATTCGGGCCCGCA
CCGGAATCACCCAGCGTCATATCGCCGGGCCGCACGACACCGCCGTCAGCATGGCGGCGGCGGCCGGGGCCCGGGCACTG
GATTATGCCGGCATGGCGGCTGCCGATGTCGGCGCGATCATCGTCGCGACCAGCACGCCCGATCAGGCCTTTCCCTCCAC
CGCCGTGCGGGTCCAGGCCGAACTGGGCCTTCGGGGCGGTTTCGGCTTCGACATCGCCGCCGCCTGCTCGGGCTTCGTCT
ACGCGCTGTCGATGGCGGATTCGCTGATCCGCAGCGGTCAGGTCGATTCCGTCCTGGTGATCGGCAGCGAGGTCTATTCG
CGCATTCTAGACTGGTCGGATCGCGGCACCTGCGTCCTGTTCGGGGACGGGGCCGGCGCGGTCCTGCTGAAGGCCGCGGA
TGGGCCGGAACCGGGAGACACCCGGCCGAAGGGTATCCTGTCCACCCATCTGCATTCCGACGGCAGCACGGGCGACCTGC
TGTATGTCGATGGGGCGATCGGCCTGCGGGAGAGTTCCGGCTTCCTGCGCATGCGGGGGCGGGACGTCTTCCGCCATGCG
GTGGCCAAGCTGTCTTCTTCGGTGGACGAGGTCCTGCACGCCAATGGCCTGACCTATGCCGACGTGAACTGGCTGGTGCC
GCACCAGGCCAATCTGCGGATCATCGAAGGTGTGGCCCGCAAGCTGGAACTGCCGCCCGAACGGGTGGTCGTGACGGTGG
ATCGTCACGCCAACACCTCGGCGGCTTCGATCCCGCTGGCGATGAACGAAGCCGTGCGCGACGGGCGTATCCGTCCCGGC
GACCTGGTGCTGATGGAAGCCCTGGGCGGCGGCCTGACATGGGGCTCGGCCCTGGCCCGAATGTAA

Upstream 100 bases:

>100_bases
GCTGGCGGCCATGCGCTCGGGTGCGGAAAAAGAGCATCCGGCGGTCGCGGCGGTAAGCTGACCGCGTGACGGGCCGGACG
GACGTCATGCCGCGGGTGCT

Downstream 100 bases:

>100_bases
CGCGGGCGGGCTGCCGGTGTGGCCCTGTAGGCGCCGGGTGTGAAAAAATAGTGTGTCCCAACGCATTGAATTGACGGCCC
ATCGCCGCATGCATACCCTT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase 3 (3-oxoacyl [acyl-carrier-protein] synthase III) (beta-ketoacyl-ACP synthase III (KAS III)

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRRVGSGAGFGMMGMMARRSLLVGFGGYLPDRIVTNDELAARLETSDEWIRARTGITQRHIAGPHDTAVSMAAAAGARAL
DYAGMAAADVGAIIVATSTPDQAFPSTAVRVQAELGLRGGFGFDIAAACSGFVYALSMADSLIRSGQVDSVLVIGSEVYS
RILDWSDRGTCVLFGDGAGAVLLKAADGPEPGDTRPKGILSTHLHSDGSTGDLLYVDGAIGLRESSGFLRMRGRDVFRHA
VAKLSSSVDEVLHANGLTYADVNWLVPHQANLRIIEGVARKLELPPERVVVTVDRHANTSAASIPLAMNEAVRDGRIRPG
DLVLMEALGGGLTWGSALARM

Sequences:

>Translated_341_residues
MRRVGSGAGFGMMGMMARRSLLVGFGGYLPDRIVTNDELAARLETSDEWIRARTGITQRHIAGPHDTAVSMAAAAGARAL
DYAGMAAADVGAIIVATSTPDQAFPSTAVRVQAELGLRGGFGFDIAAACSGFVYALSMADSLIRSGQVDSVLVIGSEVYS
RILDWSDRGTCVLFGDGAGAVLLKAADGPEPGDTRPKGILSTHLHSDGSTGDLLYVDGAIGLRESSGFLRMRGRDVFRHA
VAKLSSSVDEVLHANGLTYADVNWLVPHQANLRIIEGVARKLELPPERVVVTVDRHANTSAASIPLAMNEAVRDGRIRPG
DLVLMEALGGGLTWGSALARM
>Mature_341_residues
MRRVGSGAGFGMMGMMARRSLLVGFGGYLPDRIVTNDELAARLETSDEWIRARTGITQRHIAGPHDTAVSMAAAAGARAL
DYAGMAAADVGAIIVATSTPDQAFPSTAVRVQAELGLRGGFGFDIAAACSGFVYALSMADSLIRSGQVDSVLVIGSEVYS
RILDWSDRGTCVLFGDGAGAVLLKAADGPEPGDTRPKGILSTHLHSDGSTGDLLYVDGAIGLRESSGFLRMRGRDVFRHA
VAKLSSSVDEVLHANGLTYADVNWLVPHQANLRIIEGVARKLELPPERVVVTVDRHANTSAASIPLAMNEAVRDGRIRPG
DLVLMEALGGGLTWGSALARM

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=52.3364485981308, Blast_Score=337, Evalue=7e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35854; Mature: 35854

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVGSGAGFGMMGMMARRSLLVGFGGYLPDRIVTNDELAARLETSDEWIRARTGITQRH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHEEECCCHHHHHHHCCCCHHH
IAGPHDTAVSMAAAAGARALDYAGMAAADVGAIIVATSTPDQAFPSTAVRVQAELGLRGG
CCCCCHHHHHHHHHCCCHHHHHCCCCHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCC
FGFDIAAACSGFVYALSMADSLIRSGQVDSVLVIGSEVYSRILDWSDRGTCVLFGDGAGA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCE
VLLKAADGPEPGDTRPKGILSTHLHSDGSTGDLLYVDGAIGLRESSGFLRMRGRDVFRHA
EEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCEEECCCCEEEECCHHHHHHH
VAKLSSSVDEVLHANGLTYADVNWLVPHQANLRIIEGVARKLELPPERVVVTVDRHANTS
HHHHHHHHHHHHHCCCCEEECEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC
AASIPLAMNEAVRDGRIRPGDLVLMEALGGGLTWGSALARM
CCCCCHHHHHHHHCCCCCCCCEEEEEHHCCCCCHHHHHHCC
>Mature Secondary Structure
MRRVGSGAGFGMMGMMARRSLLVGFGGYLPDRIVTNDELAARLETSDEWIRARTGITQRH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHEEECCCHHHHHHHCCCCHHH
IAGPHDTAVSMAAAAGARALDYAGMAAADVGAIIVATSTPDQAFPSTAVRVQAELGLRGG
CCCCCHHHHHHHHHCCCHHHHHCCCCHHCCCEEEEEECCCCCCCCCCEEEEEEEECCCCC
FGFDIAAACSGFVYALSMADSLIRSGQVDSVLVIGSEVYSRILDWSDRGTCVLFGDGAGA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCE
VLLKAADGPEPGDTRPKGILSTHLHSDGSTGDLLYVDGAIGLRESSGFLRMRGRDVFRHA
EEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCEEECCCCEEEECCHHHHHHH
VAKLSSSVDEVLHANGLTYADVNWLVPHQANLRIIEGVARKLELPPERVVVTVDRHANTS
HHHHHHHHHHHHHCCCCEEECEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCC
AASIPLAMNEAVRDGRIRPGDLVLMEALGGGLTWGSALARM
CCCCCHHHHHHHHCCCCCCCCEEEEEHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA