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The map label for this gene is nouD [H]

Identifier: 162148808

GI number: 162148808

Start: 3128673

End: 3129953

Strand: Reverse

Name: nouD [H]

Synonym: GDI_3037

Alternate gene names: 162148808

Gene position: 3129953-3128673 (Counterclockwise)

Preceding gene: 162148809

Following gene: 162148807

Centisome position: 79.36

GC content: 64.48

Gene sequence:

>1281_bases
ATGCATGCGCAAGGTGAGGGGAGGCGGACGATGAGCGACATTGTCCTTCATGAGGATATTCCGGAATCCCTGCTGCCCGG
TGGCGAGGCCGCGGCGGCCGCGACCCACACGGTGGAAATCGATTCCCACGCCCTGAATTTCGGCCCGCAGCATCCGTCCG
CCCATGGTGTGCTGCGCCTGGTCCTGGAAATGGAGGGCGAGGTCGTCGCCCGCGCCATTCCGCATATCGGCCTGCTGCAT
CGCGGCACCGAAAAGCTGATCGAATACAAGACCTATCCCAAGGCCCTGCCGTATTTCGACCGGCTCGATTACGTCTCGCC
GATGTGCGAGGAGCAGGCTTTCGCGCTGGCGACCGAAAAGCTGCTGGGGATCGACATTCCCGATCGCGCGAAATGGATTC
GCGTGATGTTCGCGGAAATCACCCGGATCCTGAACCATATCCTGAACCTGACGGCGCTCGGGCTCGATTGCGGCGCGGTG
ACCCCGGCGCTGTGGGGCTACGAGGAACGCGAAAAGCTGATCGAGTTCTACGAGGCCGCGTCGGGCGCCCGGTTCCATGC
CAATTACTTCCGTCCCGGCGGGGTCTCGCGTGACCTTCCGGCGGGGCTGGAGGATCGGATCGCCGAATGGGCGCGCCAGT
TCCCGGCCTGGATCGACGATCTGGAATCGCTTCTGACCAACAACCGGATCTGGAAGCAGCGCACGGTCGGGATCGGCATC
TTCACGACCGAGCAGGCGCTGGCCTGGGGCTTCAGCGGTCCGTGCCTGCGCGCCTCGGGCGTGCCGTGGGACCTGCGCCG
CGCCCAGCCTTATGACAATTACGACAAGGTCGAGTTCAACATCCCCGTCGCGCGCCAGGGCGATTGCTACGACCGCTACC
TGATCCGCGTCGCGGAAATGCGCGAGAGCGTGCGGATCGTCGAACAGTGCCTGGCCCAGATGAAGCCCGGCCCGATCAAG
ATCCAGGACCACAAGATCACGCCGCCGCCCCGGCGCGAGATGAAGCGGTCGATGGAAGCCCTGATCCATCATTTCAAGCT
GTTCACGGAAGGGTACCACGTCCCGCCGGGGGCAACCTATACGGCGGTCGAAAGCCCCAAGGGCGAATTCGGGGTCTATC
TGGTCGCGGATGGCAGCAACCGGCCCTACCGGTGCAAGATCCGGCCGACCGGCTTCGCCCATCTGCAGGCCATCGACGAG
ATGTCGCGCCGCCACATGCTGGCCGACGCGGTGGCGATCATCGGGTCGCTGGACCTGGTGTTCGGCGAGATTGACAGGTG
A

Upstream 100 bases:

>100_bases
TTCGATTTCGAATCGCCCTGGGAAGGTATCCTGACCCTGCCGGGCGACGAGAAGGCGCATGAAACCCGCCAGGGGCTGAA
GCTGCCGCGATGACCGGGAC

Downstream 100 bases:

>100_bases
AAGAGATGTCCGCTCACTCCCCCATTGACCAGATCGAGCAGCCTTCCTCCTTCGCCTTCGATGCCGAGAGCGAGGCCGAG
ATCGCCACGATCCTGGTCAA

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MHAQGEGRRTMSDIVLHEDIPESLLPGGEAAAAATHTVEIDSHALNFGPQHPSAHGVLRLVLEMEGEVVARAIPHIGLLH
RGTEKLIEYKTYPKALPYFDRLDYVSPMCEEQAFALATEKLLGIDIPDRAKWIRVMFAEITRILNHILNLTALGLDCGAV
TPALWGYEEREKLIEFYEAASGARFHANYFRPGGVSRDLPAGLEDRIAEWARQFPAWIDDLESLLTNNRIWKQRTVGIGI
FTTEQALAWGFSGPCLRASGVPWDLRRAQPYDNYDKVEFNIPVARQGDCYDRYLIRVAEMRESVRIVEQCLAQMKPGPIK
IQDHKITPPPRREMKRSMEALIHHFKLFTEGYHVPPGATYTAVESPKGEFGVYLVADGSNRPYRCKIRPTGFAHLQAIDE
MSRRHMLADAVAIIGSLDLVFGEIDR

Sequences:

>Translated_426_residues
MHAQGEGRRTMSDIVLHEDIPESLLPGGEAAAAATHTVEIDSHALNFGPQHPSAHGVLRLVLEMEGEVVARAIPHIGLLH
RGTEKLIEYKTYPKALPYFDRLDYVSPMCEEQAFALATEKLLGIDIPDRAKWIRVMFAEITRILNHILNLTALGLDCGAV
TPALWGYEEREKLIEFYEAASGARFHANYFRPGGVSRDLPAGLEDRIAEWARQFPAWIDDLESLLTNNRIWKQRTVGIGI
FTTEQALAWGFSGPCLRASGVPWDLRRAQPYDNYDKVEFNIPVARQGDCYDRYLIRVAEMRESVRIVEQCLAQMKPGPIK
IQDHKITPPPRREMKRSMEALIHHFKLFTEGYHVPPGATYTAVESPKGEFGVYLVADGSNRPYRCKIRPTGFAHLQAIDE
MSRRHMLADAVAIIGSLDLVFGEIDR
>Mature_426_residues
MHAQGEGRRTMSDIVLHEDIPESLLPGGEAAAAATHTVEIDSHALNFGPQHPSAHGVLRLVLEMEGEVVARAIPHIGLLH
RGTEKLIEYKTYPKALPYFDRLDYVSPMCEEQAFALATEKLLGIDIPDRAKWIRVMFAEITRILNHILNLTALGLDCGAV
TPALWGYEEREKLIEFYEAASGARFHANYFRPGGVSRDLPAGLEDRIAEWARQFPAWIDDLESLLTNNRIWKQRTVGIGI
FTTEQALAWGFSGPCLRASGVPWDLRRAQPYDNYDKVEFNIPVARQGDCYDRYLIRVAEMRESVRIVEQCLAQMKPGPIK
IQDHKITPPPRREMKRSMEALIHHFKLFTEGYHVPPGATYTAVESPKGEFGVYLVADGSNRPYRCKIRPTGFAHLQAIDE
MSRRHMLADAVAIIGSLDLVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=387, Percent_Identity=66.9250645994832, Blast_Score=548, Evalue=1e-156,
Organism=Homo sapiens, GI260898743, Length=381, Percent_Identity=66.4041994750656, Blast_Score=533, Evalue=1e-151,
Organism=Escherichia coli, GI145693162, Length=387, Percent_Identity=39.2764857881137, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1789076, Length=389, Percent_Identity=25.9640102827763, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788832, Length=391, Percent_Identity=26.5984654731458, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17555284, Length=388, Percent_Identity=64.1752577319588, Blast_Score=542, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI17568379, Length=388, Percent_Identity=63.1443298969072, Blast_Score=537, Evalue=1e-153,
Organism=Drosophila melanogaster, GI24638644, Length=383, Percent_Identity=67.8851174934726, Blast_Score=561, Evalue=1e-160,
Organism=Drosophila melanogaster, GI221459469, Length=382, Percent_Identity=60.4712041884817, Blast_Score=507, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 48021; Mature: 48021

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAQGEGRRTMSDIVLHEDIPESLLPGGEAAAAATHTVEIDSHALNFGPQHPSAHGVLRL
CCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHEEEEEEECCHHCCCCCCCCCHHHHHHH
VLEMEGEVVARAIPHIGLLHRGTEKLIEYKTYPKALPYFDRLDYVSPMCEEQAFALATEK
HHHHCCHHHHHHHCCHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
LLGIDIPDRAKWIRVMFAEITRILNHILNLTALGLDCGAVTPALWGYEEREKLIEFYEAA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHC
SGARFHANYFRPGGVSRDLPAGLEDRIAEWARQFPAWIDDLESLLTNNRIWKQRTVGIGI
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCEEEE
FTTEQALAWGFSGPCLRASGVPWDLRRAQPYDNYDKVEFNIPVARQGDCYDRYLIRVAEM
EECHHHHHCCCCCCCEECCCCCCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RESVRIVEQCLAQMKPGPIKIQDHKITPPPRREMKRSMEALIHHFKLFTEGYHVPPGATY
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TAVESPKGEFGVYLVADGSNRPYRCKIRPTGFAHLQAIDEMSRRHMLADAVAIIGSLDLV
EEECCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGEIDR
HCCCCC
>Mature Secondary Structure
MHAQGEGRRTMSDIVLHEDIPESLLPGGEAAAAATHTVEIDSHALNFGPQHPSAHGVLRL
CCCCCCCCHHHHHHHHHCCCCHHHCCCCCHHHHEEEEEEECCHHCCCCCCCCCHHHHHHH
VLEMEGEVVARAIPHIGLLHRGTEKLIEYKTYPKALPYFDRLDYVSPMCEEQAFALATEK
HHHHCCHHHHHHHCCHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
LLGIDIPDRAKWIRVMFAEITRILNHILNLTALGLDCGAVTPALWGYEEREKLIEFYEAA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHC
SGARFHANYFRPGGVSRDLPAGLEDRIAEWARQFPAWIDDLESLLTNNRIWKQRTVGIGI
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCEEEE
FTTEQALAWGFSGPCLRASGVPWDLRRAQPYDNYDKVEFNIPVARQGDCYDRYLIRVAEM
EECHHHHHCCCCCCCEECCCCCCHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RESVRIVEQCLAQMKPGPIKIQDHKITPPPRREMKRSMEALIHHFKLFTEGYHVPPGATY
HHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
TAVESPKGEFGVYLVADGSNRPYRCKIRPTGFAHLQAIDEMSRRHMLADAVAIIGSLDLV
EEECCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGEIDR
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA