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The map label for this gene is ccrMIM [H]

Identifier: 162148641

GI number: 162148641

Start: 2953914

End: 2954657

Strand: Reverse

Name: ccrMIM [H]

Synonym: GDI_2868

Alternate gene names: 162148641

Gene position: 2954657-2953914 (Counterclockwise)

Preceding gene: 162148642

Following gene: 162148640

Centisome position: 74.91

GC content: 71.51

Gene sequence:

>744_bases
ATGACGCTGCTCTGCGGCGACTGCCGCGACCTCATGCCGGCGCAGGGGCCGTATGACCTGATCCTCGCCGACCCGCCCTA
CGGCGAGACCTCTCTGTCGTGGGATCGGCGCGTCGAGGGCTGGCTGCCGCTGGCAGCACAAGCCCTGACGCCGTCCGGTT
CGCTGTCGGTGTTCGGCTCCCTGCGCAGTTTCATGGCGACCGAGGTGGACTTCCGGGCCGCCCGGCTGCGGCACGCGCAG
GAGATCGTCTGGGAGAAGCAGAACGGCAGCGTGTTTCACGCTGACCGCTTCCGGCGCGTCCATGAGTTGATCGTGCAGTT
CTATCCCGCGACCGCCCGCTGGCAGGACATCTACAACGTCGTGGCGACCACGGACGACGCCCGGGCGCGGACGGTGCGCC
GCAAGCGCCGCCCGCCGCACACCGGCGCCATTGCGGCCGGCATCTATCGCAGCCTCGACGGCGGCCCGCGGCTCGCCCGC
TCCGTGCAGCGTTTCCGCAACGTCCATGGCCGCGCCATCCACCCCACCGAAAAACCGGTGCCGCTGCTCGACCTGCTGGT
GCGCGTGAGCTGCCCGCCTGACGGCCTCGTCGGTGACTGGTTCGCCGGGTCCGGCGCGGCCGGCGTCGCCTGCCGGCTGG
CCGGCCGCCGCTATGTCGGCTGCGAGATCGACCCGGACATGGCCCGGCGCGCCCGCGATCGCCTCGCCGCCATCCTTCCC
TTTCCCGTCGGAGAACCGTCATGA

Upstream 100 bases:

>100_bases
CACGTGACTTCACGGCGTCGCGTTGGTTCATCGGCTTCGCCGCCTTGGGGTTCCCATCAGACAGGCCGGTCATTCTCCCG
ACCGGCCCCGGGACACGGTC

Downstream 100 bases:

>100_bases
ACGATCTTCGCTCCCTCGTCGGCGCGCAGCTCGATCTGGTCTGGATCGAGACCCGCATCGAACAGTGGCTGCGCTTCGGC
ACCCCCGAGACCAGCGTCGC

Product: DNA methylase N-4/N-6 domain-containing protein

Products: NA

Alternate protein names: M.CcrMI; Adenine-specific methyltransferase CcrMI [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTLLCGDCRDLMPAQGPYDLILADPPYGETSLSWDRRVEGWLPLAAQALTPSGSLSVFGSLRSFMATEVDFRAARLRHAQ
EIVWEKQNGSVFHADRFRRVHELIVQFYPATARWQDIYNVVATTDDARARTVRRKRRPPHTGAIAAGIYRSLDGGPRLAR
SVQRFRNVHGRAIHPTEKPVPLLDLLVRVSCPPDGLVGDWFAGSGAAGVACRLAGRRYVGCEIDPDMARRARDRLAAILP
FPVGEPS

Sequences:

>Translated_247_residues
MTLLCGDCRDLMPAQGPYDLILADPPYGETSLSWDRRVEGWLPLAAQALTPSGSLSVFGSLRSFMATEVDFRAARLRHAQ
EIVWEKQNGSVFHADRFRRVHELIVQFYPATARWQDIYNVVATTDDARARTVRRKRRPPHTGAIAAGIYRSLDGGPRLAR
SVQRFRNVHGRAIHPTEKPVPLLDLLVRVSCPPDGLVGDWFAGSGAAGVACRLAGRRYVGCEIDPDMARRARDRLAAILP
FPVGEPS
>Mature_246_residues
TLLCGDCRDLMPAQGPYDLILADPPYGETSLSWDRRVEGWLPLAAQALTPSGSLSVFGSLRSFMATEVDFRAARLRHAQE
IVWEKQNGSVFHADRFRRVHELIVQFYPATARWQDIYNVVATTDDARARTVRRKRRPPHTGAIAAGIYRSLDGGPRLARS
VQRFRNVHGRAIHPTEKPVPLLDLLVRVSCPPDGLVGDWFAGSGAAGVACRLAGRRYVGCEIDPDMARRARDRLAAILPF
PVGEPS

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=254, Percent_Identity=25.5905511811024, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 27396; Mature: 27264

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLCGDCRDLMPAQGPYDLILADPPYGETSLSWDRRVEGWLPLAAQALTPSGSLSVFGS
CEEECCCHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCHHHHHCCCCCCHHHHHH
LRSFMATEVDFRAARLRHAQEIVWEKQNGSVFHADRFRRVHELIVQFYPATARWQDIYNV
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VATTDDARARTVRRKRRPPHTGAIAAGIYRSLDGGPRLARSVQRFRNVHGRAIHPTEKPV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCC
PLLDLLVRVSCPPDGLVGDWFAGSGAAGVACRLAGRRYVGCEIDPDMARRARDRLAAILP
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEECCCEEECCCCCHHHHHHHHHHHHHHCC
FPVGEPS
CCCCCCC
>Mature Secondary Structure 
TLLCGDCRDLMPAQGPYDLILADPPYGETSLSWDRRVEGWLPLAAQALTPSGSLSVFGS
EEECCCHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCCCCCCHHHHHCCCCCCHHHHHH
LRSFMATEVDFRAARLRHAQEIVWEKQNGSVFHADRFRRVHELIVQFYPATARWQDIYNV
HHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VATTDDARARTVRRKRRPPHTGAIAAGIYRSLDGGPRLARSVQRFRNVHGRAIHPTEKPV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCC
PLLDLLVRVSCPPDGLVGDWFAGSGAAGVACRLAGRRYVGCEIDPDMARRARDRLAAILP
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEECCCEEECCCCCHHHHHHHHHHHHHHCC
FPVGEPS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8289276 [H]