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The map label for this gene is yafC [C]

Identifier: 162148552

GI number: 162148552

Start: 2861463

End: 2862347

Strand: Direct

Name: yafC [C]

Synonym: GDI_2776

Alternate gene names: 162148552

Gene position: 2861463-2862347 (Clockwise)

Preceding gene: 162148547

Following gene: 162148554

Centisome position: 72.55

GC content: 64.41

Gene sequence:

>885_bases
ATGGACCGATATCAGGCGATGACCACGTTCGTGCGCGTGCTGGAAACAGGATCGTTCTCAGCCGCGGCGCGTCAGCTTGG
CGTGGGGCAGCCGGCGGTTTCCAAGACCGTGGCGCAACTCGAGGCCCGACTTCAGGTCAGCTTGCTGATCCGCACCACGC
ACGGCCTGACGCCGACCGAGGCCGGGCAGAACTTCTATGAACGCGCGCGCAACGCCATCCAGGAGGCGGACGAAGCAGAA
CTCGCCGCCAAAGGGGCGAGCATCGGGCTGTCCGGGCGATTGCGGGTGTCGGCCGCGACGACGTTTTCGCGCCTGCATGT
GATTCCGAAATTACCCGCGTTTCTGGCGGCGCATCCGCAACTCGATGTCGATTTCCTTCTCGACGACCGGATGATCGATC
TCGTGGCGGAGGGCGTCGATATCTCCCTGCGCATGGGTGCGCTCTCCGATTCCACGGCCGTTGTGAGAAAAGTCGCGACC
GGCCGGCGATCGGTCATCGCAACGCCCGCCTATCTGGCGCGCGCGGGAGTACCGCGGCACCCTGCGGATCTCGCGAACCA
CGACACCGTCATCTACAGTCAACTGCCAAGCGTCTGGTCGTTCACGCGGGATGGGGCGGCGGTGTCGGTTTCCGTCTCGG
GACGGCTGCGCGTCAGTGCCGCCGAAGGATTGCGCGCCGCGATACTGGCGGATATGGGCCTGACCATCACGTCGGACTGG
ATGTTCGCGCCGGAACTGGAACGCGGCGCTGTCGTGCGGGTGCTGGAAGGGTGGTCGTTGCCCCCCATCGATCTCTGGGC
CGTTTTTCCGGCCGGTCGCATGATGACCGCGAAAGCACGCCAGTTCGCAGGATTTGTCGAGGATCTGATGAATTCGATGG
TGTGA

Upstream 100 bases:

>100_bases
CTCTGGCCCGGCCTGTCCGGGTGAAGGAGACGATATCGTCCATGCCGCTCGACATGGCAGTCGTCTCGGGGCGATAAAGG
TCATTCCTCGGAGGAATGGC

Downstream 100 bases:

>100_bases
GCGGTCTCGCAGGCAATTTTCAGAATGGACGCTCTACCCGACGACAACACTGGCATGTCGTTTTACATATGCAAGCGCCA
TGTCGATGGCGAGTTCTAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDRYQAMTTFVRVLETGSFSAAARQLGVGQPAVSKTVAQLEARLQVSLLIRTTHGLTPTEAGQNFYERARNAIQEADEAE
LAAKGASIGLSGRLRVSAATTFSRLHVIPKLPAFLAAHPQLDVDFLLDDRMIDLVAEGVDISLRMGALSDSTAVVRKVAT
GRRSVIATPAYLARAGVPRHPADLANHDTVIYSQLPSVWSFTRDGAAVSVSVSGRLRVSAAEGLRAAILADMGLTITSDW
MFAPELERGAVVRVLEGWSLPPIDLWAVFPAGRMMTAKARQFAGFVEDLMNSMV

Sequences:

>Translated_294_residues
MDRYQAMTTFVRVLETGSFSAAARQLGVGQPAVSKTVAQLEARLQVSLLIRTTHGLTPTEAGQNFYERARNAIQEADEAE
LAAKGASIGLSGRLRVSAATTFSRLHVIPKLPAFLAAHPQLDVDFLLDDRMIDLVAEGVDISLRMGALSDSTAVVRKVAT
GRRSVIATPAYLARAGVPRHPADLANHDTVIYSQLPSVWSFTRDGAAVSVSVSGRLRVSAAEGLRAAILADMGLTITSDW
MFAPELERGAVVRVLEGWSLPPIDLWAVFPAGRMMTAKARQFAGFVEDLMNSMV
>Mature_294_residues
MDRYQAMTTFVRVLETGSFSAAARQLGVGQPAVSKTVAQLEARLQVSLLIRTTHGLTPTEAGQNFYERARNAIQEADEAE
LAAKGASIGLSGRLRVSAATTFSRLHVIPKLPAFLAAHPQLDVDFLLDDRMIDLVAEGVDISLRMGALSDSTAVVRKVAT
GRRSVIATPAYLARAGVPRHPADLANHDTVIYSQLPSVWSFTRDGAAVSVSVSGRLRVSAAEGLRAAILADMGLTITSDW
MFAPELERGAVVRVLEGWSLPPIDLWAVFPAGRMMTAKARQFAGFVEDLMNSMV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=31.9444444444444, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=30.5263157894737, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=28.1879194630872, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI87081978, Length=283, Percent_Identity=31.4487632508834, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=27.9151943462898, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789639, Length=272, Percent_Identity=30.5147058823529, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=274, Percent_Identity=26.2773722627737, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788297, Length=138, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789173, Length=239, Percent_Identity=29.2887029288703, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31631; Mature: 31631

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRYQAMTTFVRVLETGSFSAAARQLGVGQPAVSKTVAQLEARLQVSLLIRTTHGLTPTE
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCH
AGQNFYERARNAIQEADEAELAAKGASIGLSGRLRVSAATTFSRLHVIPKLPAFLAAHPQ
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHCCCC
LDVDFLLDDRMIDLVAEGVDISLRMGALSDSTAVVRKVATGRRSVIATPAYLARAGVPRH
CCEEEEECHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHHHCCCCCC
PADLANHDTVIYSQLPSVWSFTRDGAAVSVSVSGRLRVSAAEGLRAAILADMGLTITSDW
CHHHCCCCEEEEHHCCHHHHCCCCCCEEEEEECCEEEEEHHCCHHHHHHHHCCCEEECCC
MFAPELERGAVVRVLEGWSLPPIDLWAVFPAGRMMTAKARQFAGFVEDLMNSMV
EECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRYQAMTTFVRVLETGSFSAAARQLGVGQPAVSKTVAQLEARLQVSLLIRTTHGLTPTE
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCH
AGQNFYERARNAIQEADEAELAAKGASIGLSGRLRVSAATTFSRLHVIPKLPAFLAAHPQ
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCHHHHHCCCC
LDVDFLLDDRMIDLVAEGVDISLRMGALSDSTAVVRKVATGRRSVIATPAYLARAGVPRH
CCEEEEECHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHHHCCCCCC
PADLANHDTVIYSQLPSVWSFTRDGAAVSVSVSGRLRVSAAEGLRAAILADMGLTITSDW
CHHHCCCCEEEEHHCCHHHHCCCCCCEEEEEECCEEEEEHHCCHHHHHHHHCCCEEECCC
MFAPELERGAVVRVLEGWSLPPIDLWAVFPAGRMMTAKARQFAGFVEDLMNSMV
EECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]