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The map label for this gene is ahpC [C]

Identifier: 162148432

GI number: 162148432

Start: 2744821

End: 2745453

Strand: Direct

Name: ahpC [C]

Synonym: GDI_2651

Alternate gene names: 162148432

Gene position: 2744821-2745453 (Clockwise)

Preceding gene: 162148426

Following gene: 162148433

Centisome position: 69.59

GC content: 64.14

Gene sequence:

>633_bases
ATGACCATTCATCTCGGGGAGATCGCTCCCGATTTCGAGCAGGAAACCACCTTCGGCCCGATCCGCTTCCATGACTGGCT
GGGCGATTCCTGGGGCATCCTGTTCAGCCACCCCAAGGATTTCACGCCGGTCTGCACGACGGAACTCGGCGCCGTCGCGA
AGCTGGCACCCGAATGGGCGAAACGGAATACCAAGGTGATCGGCCTGTCCGTCGATCCGGTCGGCAGCCATTCGGAATGG
GAGAGCGATATCGCCCGGAGCCAGGGGGCGTCGGTCAATTTCCCGATCATCGCCGACGCGGACGGAACGGTCGCGGCCCT
GTACGACATGATCCATCCGTCGGCCGATCCCAAGGTGACGGTCCGCACGGTCTTCATCATCGATCCCAGCAAGAAGGTCC
GCCTGACGCTGACCTACCCGCCGTCGGCCGGCCGGAACTTCGACGAAGTGCTGCGGGTGCTGGACAGCCTGCAACTGACC
GACGCCCACAAGGTCACGACCCCGGCCAACTGGACGAACGGCGACGAAGTCATCATCGCGCCCTCGGTCGGCGACGAACA
GGCCCGTAGCCTTTTTCCCGCCGGCTGGAAGACGGTGCTGCCCTATCTGCGGCTTGTCCCGCAACCGCGATAG

Upstream 100 bases:

>100_bases
TAACATTTTCGATAGTTATATATTGAAAAGAACGACCGAATGCCGTTATCTGGTGTCCTGCCGGCATGGCGGCCATCACA
GGCAAGGGGAATCCAGTCCA

Downstream 100 bases:

>100_bases
CGCGTTTCAGGATACAGGCCATGGCGCTCTTCCCCGGCTGGACCGCACCGGATTTCACGATCGATACGGCACTGGGGCCG
GTCCGCTTCCACGCGTGGCT

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTIHLGEIAPDFEQETTFGPIRFHDWLGDSWGILFSHPKDFTPVCTTELGAVAKLAPEWAKRNTKVIGLSVDPVGSHSEW
ESDIARSQGASVNFPIIADADGTVAALYDMIHPSADPKVTVRTVFIIDPSKKVRLTLTYPPSAGRNFDEVLRVLDSLQLT
DAHKVTTPANWTNGDEVIIAPSVGDEQARSLFPAGWKTVLPYLRLVPQPR

Sequences:

>Translated_210_residues
MTIHLGEIAPDFEQETTFGPIRFHDWLGDSWGILFSHPKDFTPVCTTELGAVAKLAPEWAKRNTKVIGLSVDPVGSHSEW
ESDIARSQGASVNFPIIADADGTVAALYDMIHPSADPKVTVRTVFIIDPSKKVRLTLTYPPSAGRNFDEVLRVLDSLQLT
DAHKVTTPANWTNGDEVIIAPSVGDEQARSLFPAGWKTVLPYLRLVPQPR
>Mature_209_residues
TIHLGEIAPDFEQETTFGPIRFHDWLGDSWGILFSHPKDFTPVCTTELGAVAKLAPEWAKRNTKVIGLSVDPVGSHSEWE
SDIARSQGASVNFPIIADADGTVAALYDMIHPSADPKVTVRTVFIIDPSKKVRLTLTYPPSAGRNFDEVLRVLDSLQLTD
AHKVTTPANWTNGDEVIIAPSVGDEQARSLFPAGWKTVLPYLRLVPQPR

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=218, Percent_Identity=52.7522935779816, Blast_Score=223, Evalue=9e-59,
Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI32189392, Length=189, Percent_Identity=31.2169312169312, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5453549, Length=169, Percent_Identity=33.1360946745562, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI32483377, Length=156, Percent_Identity=29.4871794871795, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI5802974, Length=156, Percent_Identity=29.4871794871795, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=29.8701298701299, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25153706, Length=223, Percent_Identity=39.0134529147982, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193204376, Length=188, Percent_Identity=32.4468085106383, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565831, Length=188, Percent_Identity=32.4468085106383, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17554494, Length=171, Percent_Identity=32.1637426900585, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319407, Length=210, Percent_Identity=51.9047619047619, Blast_Score=218, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6323613, Length=203, Percent_Identity=29.064039408867, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24652434, Length=206, Percent_Identity=52.4271844660194, Blast_Score=203, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24652436, Length=205, Percent_Identity=52.1951219512195, Blast_Score=202, Evalue=9e-53,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=52.1951219512195, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24581278, Length=218, Percent_Identity=48.1651376146789, Blast_Score=198, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17738015, Length=191, Percent_Identity=32.4607329842932, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17157991, Length=165, Percent_Identity=33.9393939393939, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641739, Length=165, Percent_Identity=33.9393939393939, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357347, Length=189, Percent_Identity=27.5132275132275, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24656348, Length=176, Percent_Identity=30.1136363636364, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17864676, Length=176, Percent_Identity=30.1136363636364, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23083; Mature: 22952

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHLGEIAPDFEQETTFGPIRFHDWLGDSWGILFSHPKDFTPVCTTELGAVAKLAPEWA
CEEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCHHHH
KRNTKVIGLSVDPVGSHSEWESDIARSQGASVNFPIIADADGTVAALYDMIHPSADPKVT
CCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCEE
VRTVFIIDPSKKVRLTLTYPPSAGRNFDEVLRVLDSLQLTDAHKVTTPANWTNGDEVIIA
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEEEE
PSVGDEQARSLFPAGWKTVLPYLRLVPQPR
CCCCCHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIHLGEIAPDFEQETTFGPIRFHDWLGDSWGILFSHPKDFTPVCTTELGAVAKLAPEWA
EEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCHHHH
KRNTKVIGLSVDPVGSHSEWESDIARSQGASVNFPIIADADGTVAALYDMIHPSADPKVT
CCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCEE
VRTVFIIDPSKKVRLTLTYPPSAGRNFDEVLRVLDSLQLTDAHKVTTPANWTNGDEVIIA
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEECCCCCCCCCCEEEEE
PSVGDEQARSLFPAGWKTVLPYLRLVPQPR
CCCCCHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]