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The map label for this gene is nagA [H]

Identifier: 162148362

GI number: 162148362

Start: 2672586

End: 2673860

Strand: Reverse

Name: nagA [H]

Synonym: GDI_2579

Alternate gene names: 162148362

Gene position: 2673860-2672586 (Counterclockwise)

Preceding gene: 162148364

Following gene: 162148360

Centisome position: 67.79

GC content: 69.73

Gene sequence:

>1275_bases
ATGGCCGGTACTCCTGGCGGTACCGGAACAACGGCGGAACGTCGGCCGGGGTTGTGGGGCGGGACCGTTATTTACTGTAC
AACCGGCATGATGCATGCGAAAAGCCGGGCTGGTTCAAGGCGCAATGCCGGTGTTTGGGGAAATGGTCCGATCATGATCC
TTCGGGGAAACCTCGTCCTGCCGGACCGGGTGGCGGCGGGGCGCATCACCTTCGACGGGACGATCCGCGCCATCGCGCCG
GACGAGGTGAGCGGCGGGGATGGACCGGCCGAGGCACTCTATATCCTGCCGGGCTTCATCGACGCGCATGTGCATGGCGG
TGACGGCGCCGACACGATGGACGGCGCGGCGGCGATCCGGCGCATGGCGCGGTTTCACCTGGTCCATGGCACGACGACGA
TCCTGCCGACCACCATTACGCGGCCATGGCCGGACGTGATGGACGCGCTGCATGCGGTGGCCGAGGTGAAGCAGGCCGGG
ATGGCGGACGGCCCGGTCATCCATGGCGCGCATCTGGAAGGTCCGTTCGTCAGTCCGCATCGGCTGGGGGCGCAGCCGCC
CTTCGCCATCGCCCCGGACCCCCATCATGTCCGTGCGGCGCTGCAGACCGGGGTGGTGCGCGTCGTGACGCTGGCGCCGG
AACTGGAGCATGCGGACAGCGCCATTGCCGCCTTCGCCGCCGCCGGCGTGCGCGTCAGCATCGGCCACACCGTCGCCGGC
TTCGAACAGGCCGAACAGGCGATCTGCCGGATCTGCGCCGCCGGCGGGACGGCGGGCGGCACCCATCTGTTCAACGCCAT
GGGCGGGATCGAGGGCCGCCGGCCCGGCCCGGCGACGGCGCTGCTATGCAGCGATGCCGGTCATGCCGAACTGATCTTCG
ACACCCATCATGTCCATCCTGCCAGCTTCCGCCTGGCGCACCGGCTGCTGGGCGACCGCCTGCTGTTCGTGACCGACGCC
ATGCGCGGCGCGGGGCAGGGTGACGGGATCAGCCAGCTCGGTGGGCAGGAGGTGACGATCCGCGACGGAATTGCGCGCCT
GCCTGACGGCACGCTGGCCGGCAGCGTACTGACGCTGGATGGGGCGCTGCGCAACGCGATCGCGGCCGGCACCGATCTGG
TCGATGCCGCGAAGCTGGTTAGCCGGAATGCCGCGCACTATCTGGGCCTGCGGGATCGCGGCGCGCTGCTGCCCGGCCTG
CGGGCCGATTTCGTGGTGATGGACCGCGAATTCATGGTGCGCGAGGTCTGGGTCGGCGGCGAACGCCGCTTCTGA

Upstream 100 bases:

>100_bases
GACCAGAACCGAAATCTTCAGCCGGTTGGCCAGCATTCCCAGCACGAAGGCCAATGTCAGGCCGACGACCAGGATGGTGA
TCAGGGGGCTGGCGTGGGAC

Downstream 100 bases:

>100_bases
AATTTTCCTATCGGGCCTGTGGCGCGGTACTGCCGCGTTCGACCAGCCGGGCGGGAACGGTGCGGGTCCGCCCTTTCGCC
GCTGTCGCTGGGTCGGCCAG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MAGTPGGTGTTAERRPGLWGGTVIYCTTGMMHAKSRAGSRRNAGVWGNGPIMILRGNLVLPDRVAAGRITFDGTIRAIAP
DEVSGGDGPAEALYILPGFIDAHVHGGDGADTMDGAAAIRRMARFHLVHGTTTILPTTITRPWPDVMDALHAVAEVKQAG
MADGPVIHGAHLEGPFVSPHRLGAQPPFAIAPDPHHVRAALQTGVVRVVTLAPELEHADSAIAAFAAAGVRVSIGHTVAG
FEQAEQAICRICAAGGTAGGTHLFNAMGGIEGRRPGPATALLCSDAGHAELIFDTHHVHPASFRLAHRLLGDRLLFVTDA
MRGAGQGDGISQLGGQEVTIRDGIARLPDGTLAGSVLTLDGALRNAIAAGTDLVDAAKLVSRNAAHYLGLRDRGALLPGL
RADFVVMDREFMVREVWVGGERRF

Sequences:

>Translated_424_residues
MAGTPGGTGTTAERRPGLWGGTVIYCTTGMMHAKSRAGSRRNAGVWGNGPIMILRGNLVLPDRVAAGRITFDGTIRAIAP
DEVSGGDGPAEALYILPGFIDAHVHGGDGADTMDGAAAIRRMARFHLVHGTTTILPTTITRPWPDVMDALHAVAEVKQAG
MADGPVIHGAHLEGPFVSPHRLGAQPPFAIAPDPHHVRAALQTGVVRVVTLAPELEHADSAIAAFAAAGVRVSIGHTVAG
FEQAEQAICRICAAGGTAGGTHLFNAMGGIEGRRPGPATALLCSDAGHAELIFDTHHVHPASFRLAHRLLGDRLLFVTDA
MRGAGQGDGISQLGGQEVTIRDGIARLPDGTLAGSVLTLDGALRNAIAAGTDLVDAAKLVSRNAAHYLGLRDRGALLPGL
RADFVVMDREFMVREVWVGGERRF
>Mature_423_residues
AGTPGGTGTTAERRPGLWGGTVIYCTTGMMHAKSRAGSRRNAGVWGNGPIMILRGNLVLPDRVAAGRITFDGTIRAIAPD
EVSGGDGPAEALYILPGFIDAHVHGGDGADTMDGAAAIRRMARFHLVHGTTTILPTTITRPWPDVMDALHAVAEVKQAGM
ADGPVIHGAHLEGPFVSPHRLGAQPPFAIAPDPHHVRAALQTGVVRVVTLAPELEHADSAIAAFAAAGVRVSIGHTVAGF
EQAEQAICRICAAGGTAGGTHLFNAMGGIEGRRPGPATALLCSDAGHAELIFDTHHVHPASFRLAHRLLGDRLLFVTDAM
RGAGQGDGISQLGGQEVTIRDGIARLPDGTLAGSVLTLDGALRNAIAAGTDLVDAAKLVSRNAAHYLGLRDRGALLPGLR
ADFVVMDREFMVREVWVGGERRF

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=381, Percent_Identity=34.9081364829396, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI224922791, Length=380, Percent_Identity=34.7368421052632, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1786892, Length=364, Percent_Identity=31.043956043956, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17553768, Length=359, Percent_Identity=32.3119777158774, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI19920392, Length=343, Percent_Identity=30.6122448979592, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI281361140, Length=357, Percent_Identity=29.9719887955182, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 44149; Mature: 44018

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTPGGTGTTAERRPGLWGGTVIYCTTGMMHAKSRAGSRRNAGVWGNGPIMILRGNLVL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCCEEEEECCEEC
PDRVAAGRITFDGTIRAIAPDEVSGGDGPAEALYILPGFIDAHVHGGDGADTMDGAAAIR
CCCCCCCEEEECCEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCHHHHHHHH
RMARFHLVHGTTTILPTTITRPWPDVMDALHAVAEVKQAGMADGPVIHGAHLEGPFVSPH
HHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHH
RLGAQPPFAIAPDPHHVRAALQTGVVRVVTLAPELEHADSAIAAFAAAGVRVSIGHTVAG
HCCCCCCEEECCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCEEEEECCCHHH
FEQAEQAICRICAAGGTAGGTHLFNAMGGIEGRRPGPATALLCSDAGHAELIFDTHHVHP
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCC
ASFRLAHRLLGDRLLFVTDAMRGAGQGDGISQLGGQEVTIRDGIARLPDGTLAGSVLTLD
HHHHHHHHHHCCEEEEEEHHHHCCCCCCCHHHCCCCEEEECCCHHHCCCCCCCCEEEEEC
GALRNAIAAGTDLVDAAKLVSRNAAHYLGLRDRGALLPGLRADFVVMDREFMVREVWVGG
HHHHHHHHCCCHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCEEEECHHHHHHHHCCCC
ERRF
CCCC
>Mature Secondary Structure 
AGTPGGTGTTAERRPGLWGGTVIYCTTGMMHAKSRAGSRRNAGVWGNGPIMILRGNLVL
CCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCCCCEEEEECCEEC
PDRVAAGRITFDGTIRAIAPDEVSGGDGPAEALYILPGFIDAHVHGGDGADTMDGAAAIR
CCCCCCCEEEECCEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCHHHHHHHH
RMARFHLVHGTTTILPTTITRPWPDVMDALHAVAEVKQAGMADGPVIHGAHLEGPFVSPH
HHHHHHEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHH
RLGAQPPFAIAPDPHHVRAALQTGVVRVVTLAPELEHADSAIAAFAAAGVRVSIGHTVAG
HCCCCCCEEECCCHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHCCEEEEECCCHHH
FEQAEQAICRICAAGGTAGGTHLFNAMGGIEGRRPGPATALLCSDAGHAELIFDTHHVHP
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCC
ASFRLAHRLLGDRLLFVTDAMRGAGQGDGISQLGGQEVTIRDGIARLPDGTLAGSVLTLD
HHHHHHHHHHCCEEEEEEHHHHCCCCCCCHHHCCCCEEEECCCHHHCCCCCCCCEEEEEC
GALRNAIAAGTDLVDAAKLVSRNAAHYLGLRDRGALLPGLRADFVVMDREFMVREVWVGG
HHHHHHHHCCCHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCEEEECHHHHHHHHCCCC
ERRF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA