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The map label for this gene is glcB [H]

Identifier: 162148233

GI number: 162148233

Start: 2540585

End: 2542798

Strand: Direct

Name: glcB [H]

Synonym: GDI_2450

Alternate gene names: 162148233

Gene position: 2540585-2542798 (Clockwise)

Preceding gene: 162148232

Following gene: 162148257

Centisome position: 64.41

GC content: 68.97

Gene sequence:

>2214_bases
ATGTCCCGTCGCACGATCGGCCAGCTTCGCATCCATCATGCCCTCGATGCCTTCGTCACGCACGAAGTCCTGCCGGGAAC
CGGCGTTTCCGCCGACCGGTTCTGGATGGGCCTGTCGGACATCGTCACCCATTTCACGCCGAAGATCCTGAACGCCCTGG
CGCGCCGCCGCCTGTTGCAGCAGGCCGTGGACCATCTGCTGACCGCACCCGGATTCGATCCCGGCGATGTCGGCGCGCAG
ATCGACCTGCTGCGCACCGTCGGCTATCTGGAGCGCGAGCCGGAGAGCGTGTCGATCGCCACCCGTGACGTCGATGCCGA
AATCGCGCGCATCGCCGGGCCCCAGCTTGTGGTTCCCGTCACCAACGCCCGCTATGCGCTGAATGCCGCCAACGCCCGCT
GGGGCAGCCTGTATGACGCGTTCTACGGCACCGACGCCGAGCCGTACGACATGCAAGGCGTTCCCACCGCCGGCTATGAC
ACGCAGCGCGGCGAGCGGGTGATCCGGCGGGTACGGCTGCTGCTGGACGAAATCATGCCGCTGACGCGCGGCAGCCACGC
CGACGTCGCGCGCTATCGGGTCGAGGACGGCCGGTTGACGGCGGCGCTCGACGACGGCGCGCCGCCGGCCGGCCTGCGCC
GTCCGGCACAGTTCGCCGGATTCCAGGGACCGCCGGACGCGCCCCGGGTGGTCCTGCTGCGCAATCACGGCCTGCATCTG
GAACTGCGCTTCGACCCGACATCGCCGATCGGCAGCCGGGACCGCGCCGGGATATCCGACGTGATCGCGGAATCCGCGAT
CAGCACCATCATGGATTGCGAGGACAGCGTTTCGGCGGTCGATGTCGAGGACAAGATCCAGGTCTATCGCAACTGGCTGG
GCCTGATGCAGGGCACCCTGACCGCGTCGTTCCGCAAGGGCGGCCGCCTGCTGGAACGGCGCCTGGCCCCCGACCGGCAC
TACACCGCGCCCGACGGCACGCCGCTGGTGCTGCCGGGGCGCAGCCTGATGCTGATCCGCAATGTCGGCCACCACATGTT
CACCGATGCGATCGTGGACACTGGCGGCCACCCGGTGCCCGAGGGCGTGCTGGACGCCGCCGTGACCGCCGTCATCGCCC
TGCACGACCTGCGCGGAACGTCGCGCACCACCAACAGCCGGACGGGATCGATCTATATCGTCAAGCCCAAGATGCACGGG
CCGGAAGAGGTCGCCTTGTCCGACGCCCTGTTCGCGCGCGTCGAACGGGTGCTGGGCCTGGGGCCGAACACCATCAAGAT
GGGCATCATGGACGAGGAACGGCGGACCAGCGCCAACCTGGCCGCCTGCATCCAGGCCGCGCGCGAGCGGGTGGTGTTCA
TCAATACCGGCTTCCTGGACCGCACGGGGGACGAGATCCATTACTGCATGCAGGCCGGCCCCGTAGTGCGCAAGGCCGAC
ATGCGCGCCGAGCCGTGGATGGCGGCATACGAACAGCGCAACGTCGCGATCGGCCTGGCCTGCGGGCTGAAGGACCATGC
CCAGATCGGCAAGGGCATGTGGGCGATGCCGGACCGCATGGCCGACATGATGACGCAGAAGATCGCCCACCCCCGCGCGG
GCGCCAATACGGGCTGGGTGCCCTCGCCCACCGCGGCGACGCTGCATGCGCTGCATTTTCACTTCGTCGACGTGGCGACG
GTGCAGGCGCGGATGGAAAACGTGCCGCCGGCCGCCATCAAGGGGCTGATGACCCTGCCGCTGGCCGATCCGGCGGCGTG
GTCGGCGGCGGAGCGCCGGGCCGAACTGGACAACAACCTGCAGGGCATCCTGGGTTATGTCGTCCGGTGGGTGGATATGG
GCATCGGCTGTTCCAAGGTGCCGGACCTGGACGATGTCGGCCTGATGGAGGACCGCGCGACGCTGCGCATTTCCTCGCAG
CACGTCGCGAACTGGCTGCATCATGGCGTGGTGTCGCAAGACGAGGTCCGGGCGTCCATGATCCGCATGGCCGCCATCGT
GGACGGGCAGAATCGCGACGAGCCCGGCTATCGCCCGCTGGCCGACAACGCAGGCGGCCCGGCCTTCCGCGCCGCGTCGG
ACCTGGTGTTCAAGGGCGTGACCCAGCCCAACGGCTATACCGAGTCCACGCTGCATCGCTGGCGCCGGGTGGCCAAGGAC
GGCGCCGCCGCGGCGAACCGGACGGTGCCGGAACTGGACCGGGCCGTTCCGTAA

Upstream 100 bases:

>100_bases
GCCGGGCCGCGTGCCCGGCCGCCGAACCCGACCGCAGACCCGACCACAGACCAGACACCGGAAGACAGACCCGAAAAAGG
GCCCGAAAAGGGGAAAGACC

Downstream 100 bases:

>100_bases
CGGGGTGATCGAACGGGCGGCGGGCGGCCGGTCAGGCGCGCAGATGCTCCAGCCGCAGCCGCCCGCGGGCGTCGCTCAGC
CGTGCCGCCGTCAGTCCGGC

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 736

Protein sequence:

>737_residues
MSRRTIGQLRIHHALDAFVTHEVLPGTGVSADRFWMGLSDIVTHFTPKILNALARRRLLQQAVDHLLTAPGFDPGDVGAQ
IDLLRTVGYLEREPESVSIATRDVDAEIARIAGPQLVVPVTNARYALNAANARWGSLYDAFYGTDAEPYDMQGVPTAGYD
TQRGERVIRRVRLLLDEIMPLTRGSHADVARYRVEDGRLTAALDDGAPPAGLRRPAQFAGFQGPPDAPRVVLLRNHGLHL
ELRFDPTSPIGSRDRAGISDVIAESAISTIMDCEDSVSAVDVEDKIQVYRNWLGLMQGTLTASFRKGGRLLERRLAPDRH
YTAPDGTPLVLPGRSLMLIRNVGHHMFTDAIVDTGGHPVPEGVLDAAVTAVIALHDLRGTSRTTNSRTGSIYIVKPKMHG
PEEVALSDALFARVERVLGLGPNTIKMGIMDEERRTSANLAACIQAARERVVFINTGFLDRTGDEIHYCMQAGPVVRKAD
MRAEPWMAAYEQRNVAIGLACGLKDHAQIGKGMWAMPDRMADMMTQKIAHPRAGANTGWVPSPTAATLHALHFHFVDVAT
VQARMENVPPAAIKGLMTLPLADPAAWSAAERRAELDNNLQGILGYVVRWVDMGIGCSKVPDLDDVGLMEDRATLRISSQ
HVANWLHHGVVSQDEVRASMIRMAAIVDGQNRDEPGYRPLADNAGGPAFRAASDLVFKGVTQPNGYTESTLHRWRRVAKD
GAAAANRTVPELDRAVP

Sequences:

>Translated_737_residues
MSRRTIGQLRIHHALDAFVTHEVLPGTGVSADRFWMGLSDIVTHFTPKILNALARRRLLQQAVDHLLTAPGFDPGDVGAQ
IDLLRTVGYLEREPESVSIATRDVDAEIARIAGPQLVVPVTNARYALNAANARWGSLYDAFYGTDAEPYDMQGVPTAGYD
TQRGERVIRRVRLLLDEIMPLTRGSHADVARYRVEDGRLTAALDDGAPPAGLRRPAQFAGFQGPPDAPRVVLLRNHGLHL
ELRFDPTSPIGSRDRAGISDVIAESAISTIMDCEDSVSAVDVEDKIQVYRNWLGLMQGTLTASFRKGGRLLERRLAPDRH
YTAPDGTPLVLPGRSLMLIRNVGHHMFTDAIVDTGGHPVPEGVLDAAVTAVIALHDLRGTSRTTNSRTGSIYIVKPKMHG
PEEVALSDALFARVERVLGLGPNTIKMGIMDEERRTSANLAACIQAARERVVFINTGFLDRTGDEIHYCMQAGPVVRKAD
MRAEPWMAAYEQRNVAIGLACGLKDHAQIGKGMWAMPDRMADMMTQKIAHPRAGANTGWVPSPTAATLHALHFHFVDVAT
VQARMENVPPAAIKGLMTLPLADPAAWSAAERRAELDNNLQGILGYVVRWVDMGIGCSKVPDLDDVGLMEDRATLRISSQ
HVANWLHHGVVSQDEVRASMIRMAAIVDGQNRDEPGYRPLADNAGGPAFRAASDLVFKGVTQPNGYTESTLHRWRRVAKD
GAAAANRTVPELDRAVP
>Mature_736_residues
SRRTIGQLRIHHALDAFVTHEVLPGTGVSADRFWMGLSDIVTHFTPKILNALARRRLLQQAVDHLLTAPGFDPGDVGAQI
DLLRTVGYLEREPESVSIATRDVDAEIARIAGPQLVVPVTNARYALNAANARWGSLYDAFYGTDAEPYDMQGVPTAGYDT
QRGERVIRRVRLLLDEIMPLTRGSHADVARYRVEDGRLTAALDDGAPPAGLRRPAQFAGFQGPPDAPRVVLLRNHGLHLE
LRFDPTSPIGSRDRAGISDVIAESAISTIMDCEDSVSAVDVEDKIQVYRNWLGLMQGTLTASFRKGGRLLERRLAPDRHY
TAPDGTPLVLPGRSLMLIRNVGHHMFTDAIVDTGGHPVPEGVLDAAVTAVIALHDLRGTSRTTNSRTGSIYIVKPKMHGP
EEVALSDALFARVERVLGLGPNTIKMGIMDEERRTSANLAACIQAARERVVFINTGFLDRTGDEIHYCMQAGPVVRKADM
RAEPWMAAYEQRNVAIGLACGLKDHAQIGKGMWAMPDRMADMMTQKIAHPRAGANTGWVPSPTAATLHALHFHFVDVATV
QARMENVPPAAIKGLMTLPLADPAAWSAAERRAELDNNLQGILGYVVRWVDMGIGCSKVPDLDDVGLMEDRATLRISSQH
VANWLHHGVVSQDEVRASMIRMAAIVDGQNRDEPGYRPLADNAGGPAFRAASDLVFKGVTQPNGYTESTLHRWRRVAKDG
AAAANRTVPELDRAVP

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=725, Percent_Identity=56.8275862068966, Blast_Score=813, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 80411; Mature: 80280

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRTIGQLRIHHALDAFVTHEVLPGTGVSADRFWMGLSDIVTHFTPKILNALARRRLLQ
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QAVDHLLTAPGFDPGDVGAQIDLLRTVGYLEREPESVSIATRDVDAEIARIAGPQLVVPV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCEEEEEE
TNARYALNAANARWGSLYDAFYGTDAEPYDMQGVPTAGYDTQRGERVIRRVRLLLDEIMP
CCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTRGSHADVARYRVEDGRLTAALDDGAPPAGLRRPAQFAGFQGPPDAPRVVLLRNHGLHL
HCCCCCCCHHHEEECCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEE
ELRFDPTSPIGSRDRAGISDVIAESAISTIMDCEDSVSAVDVEDKIQVYRNWLGLMQGTL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TASFRKGGRLLERRLAPDRHYTAPDGTPLVLPGRSLMLIRNVGHHMFTDAIVDTGGHPVP
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHCHHHHHHHHHCCCCCCCC
EGVLDAAVTAVIALHDLRGTSRTTNSRTGSIYIVKPKMHGPEEVALSDALFARVERVLGL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
GPNTIKMGIMDEERRTSANLAACIQAARERVVFINTGFLDRTGDEIHYCMQAGPVVRKAD
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCHHHCC
MRAEPWMAAYEQRNVAIGLACGLKDHAQIGKGMWAMPDRMADMMTQKIAHPRAGANTGWV
CCCCCHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSPTAATLHALHFHFVDVATVQARMENVPPAAIKGLMTLPLADPAAWSAAERRAELDNNL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHHHHHCCHH
QGILGYVVRWVDMGIGCSKVPDLDDVGLMEDRATLRISSQHVANWLHHGVVSQDEVRASM
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHH
IRMAAIVDGQNRDEPGYRPLADNAGGPAFRAASDLVFKGVTQPNGYTESTLHRWRRVAKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GAAAANRTVPELDRAVP
CHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
SRRTIGQLRIHHALDAFVTHEVLPGTGVSADRFWMGLSDIVTHFTPKILNALARRRLLQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
QAVDHLLTAPGFDPGDVGAQIDLLRTVGYLEREPESVSIATRDVDAEIARIAGPQLVVPV
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCEEEEEE
TNARYALNAANARWGSLYDAFYGTDAEPYDMQGVPTAGYDTQRGERVIRRVRLLLDEIMP
CCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LTRGSHADVARYRVEDGRLTAALDDGAPPAGLRRPAQFAGFQGPPDAPRVVLLRNHGLHL
HCCCCCCCHHHEEECCCEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEE
ELRFDPTSPIGSRDRAGISDVIAESAISTIMDCEDSVSAVDVEDKIQVYRNWLGLMQGTL
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TASFRKGGRLLERRLAPDRHYTAPDGTPLVLPGRSLMLIRNVGHHMFTDAIVDTGGHPVP
HHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHCHHHHHHHHHCCCCCCCC
EGVLDAAVTAVIALHDLRGTSRTTNSRTGSIYIVKPKMHGPEEVALSDALFARVERVLGL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCC
GPNTIKMGIMDEERRTSANLAACIQAARERVVFINTGFLDRTGDEIHYCMQAGPVVRKAD
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCHHHCC
MRAEPWMAAYEQRNVAIGLACGLKDHAQIGKGMWAMPDRMADMMTQKIAHPRAGANTGWV
CCCCCHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSPTAATLHALHFHFVDVATVQARMENVPPAAIKGLMTLPLADPAAWSAAERRAELDNNL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCHHHHHHHHHHHHCCHH
QGILGYVVRWVDMGIGCSKVPDLDDVGLMEDRATLRISSQHVANWLHHGVVSQDEVRASM
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHH
IRMAAIVDGQNRDEPGYRPLADNAGGPAFRAASDLVFKGVTQPNGYTESTLHRWRRVAKD
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GAAAANRTVPELDRAVP
CHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA