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The map label for this gene is kup [H]

Identifier: 162148168

GI number: 162148168

Start: 2459550

End: 2461469

Strand: Direct

Name: kup [H]

Synonym: GDI_2385

Alternate gene names: 162148168

Gene position: 2459550-2461469 (Clockwise)

Preceding gene: 162148167

Following gene: 162148169

Centisome position: 62.36

GC content: 65.57

Gene sequence:

>1920_bases
GTGGCGGACGTGCCGACGAAAATCACCGAATTCGGCGCCGACCAGCATGAACATGCGGCCAATCCGGTCGGTTTCGCCGC
CCTCATGGTCGTGCTGGGCGTGGTCTTCGGCGATATCGGGACAAGCCCGCTCTACGCCCTGCGATCGACCATCCTGGTCG
TGTCGCAGCACCACCAGATCGAAGCCTGGGAGGTGATGGGCGTCGAAAGCCTGATCCTGTGGTCGCTGATCCTGATCGTC
ACCGTGAAATACGTGCTGCTGATCATGCGCGCCGACCATAATGGCGAGGGCGGGATCATCTCGCTGATGTCGCTGGCCCA
GCGCGTGTCGGAAAACACCCGGCTGAAGCTGGTGCTGGGCATGACCGGCATCGCCGGGGCGTGCCTGTTCTTCGGCGACG
GGCTGATCACGCCCGCGATTTCGGTCCTGTCGGCGGTCGAGGGGCTGGAGGTCAGCTTTCCCGCGGCCCACGACCTGGTC
ATTCCCGTGGCCATCATGGTGCTGATCGGGCTGTTCAGCGTCCAGTCGGCCGGCACGGGCAAGGTCGGCACGGTCTTCGG
CCCCGTCATGCTGCTCTGGTTCAGCATGCTGGGCATCCTGGGCATGCTGCAGATCCTGCGCCATCCGGGCATCCTGATGG
CGATCTCGCCGATCTATGCCGTGCGCTTCATCGCCTTTCACGGCTGGCTGTCGTTCATCGCGCTGGGGTCGGTGGTGCTG
TCGGTCACCGGGGCCGAGGCCCTGTACGCCGACATGGGACATTTCGGCCGCCAGCCCATCCGCTACGCCTGGCTGTTCTG
CGTCCTGCCCTGCCTCGCGCTGAACTACATGGGCCAGGGGGCGCTGATCATCGCCACGCCGTCGGCGCTGAGCAATCCGT
TCTTCCTGCTGGGTCCGCACTGGATGCAGATCCCGATGGTCATCCTGTCGACGATGGCCACCGTCATCGCCAGCCAGGCC
GGAATTTCCGGCGGGTTCTCGCTCTGTCGGCAGTTGATCCAGCTCGGCTACCTGCCGCGCATGCGCATCACCCACACCAA
CAAGAACGAGGAAGGGCAGATCTACCTGCCCGAGTTCAACCGCTTCCTGATGGTGGGCGCGCTGACGCTGGTGGTGGCGT
TCCGCAGTTCCGACGCCCTGGCCTCGGCCTACGGCATCGCGGTGACGGGCACCTTCATGTGCACCTGCGTCCTGGCGATG
GTGGCGTTCCGCCGCCTGTATCACTGGTCGCGGGCGGCGGCGGCGTTCACGTTCGGCGGCTTCTTCGTCATGGACAGCAT
CTTCTTCGCGTCCAATGCGCTGAAGATCCCGCAGGGCGGCTGGGTGCCGGTGCTGCTGGGCATCGCGCTGACCCTGATGA
TGACGACGTGGAAGCGCGGCCGCGGCCTGATCATGAACCGGCAGAAGCTGGACAGCCTGCCGGTCAATTCCTTCCTGGCG
CGCCTGCCGCAGTCGCGCACCATCCGCGTGCCCGGCACGGCGGTGTTCATGACCGCGACGCCGGAATTCGTGCCCACCTG
CCTGCTGCACAACCTGAAGCACAACAAGGTGCTGCACGAGCACGTGCTGTTCGTCACGGTCCAGACCCTGGACCAGCCCG
AGGCCACGCGCGGCCACCGGGTGGCGCTGCAGCTTCTGGCACCCAATATCTACCGGGTGATCCTGCGCTACGGCTTCATG
GAAACCCCGAACCTGCCCCGCGCGCTGGAGGACCTGAAGGCCAACGGCGTGGATTTCGACGTCATGCAGGCATCCTATTT
CACCAGCCGCGAACTGCTGGTCCGGTCCTCGGTGCCCAAGATGTCGCGCTGGCGGATGTCGCTGTTCCTGCTGATGGCGC
GCAACGCCACCCCCGCCACCGAATTCTTCCGCATCCCGCCGGACCGGGTCGTGGAACTGGGCGTGCGGCTTGCCATCTGA

Upstream 100 bases:

>100_bases
GATCTGACTGCGGAGACGTCCCGACATGACGCCAGTCCCGGGCGATATGGCCCCCGGATCCCTGCCTTCCGCCCCGGCGA
GCCCGAACGCCGCGGGGGGC

Downstream 100 bases:

>100_bases
CGCCGCACCGCTCGCGCTCTATATCCACTGGCCATTCTGCCTGGCCAAATGTCCGTACTGCGATTTCAACAGCCATGTCC
GCGATGTCATCCCCCAGGCC

Product: potassium transport system protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MADVPTKITEFGADQHEHAANPVGFAALMVVLGVVFGDIGTSPLYALRSTILVVSQHHQIEAWEVMGVESLILWSLILIV
TVKYVLLIMRADHNGEGGIISLMSLAQRVSENTRLKLVLGMTGIAGACLFFGDGLITPAISVLSAVEGLEVSFPAAHDLV
IPVAIMVLIGLFSVQSAGTGKVGTVFGPVMLLWFSMLGILGMLQILRHPGILMAISPIYAVRFIAFHGWLSFIALGSVVL
SVTGAEALYADMGHFGRQPIRYAWLFCVLPCLALNYMGQGALIIATPSALSNPFFLLGPHWMQIPMVILSTMATVIASQA
GISGGFSLCRQLIQLGYLPRMRITHTNKNEEGQIYLPEFNRFLMVGALTLVVAFRSSDALASAYGIAVTGTFMCTCVLAM
VAFRRLYHWSRAAAAFTFGGFFVMDSIFFASNALKIPQGGWVPVLLGIALTLMMTTWKRGRGLIMNRQKLDSLPVNSFLA
RLPQSRTIRVPGTAVFMTATPEFVPTCLLHNLKHNKVLHEHVLFVTVQTLDQPEATRGHRVALQLLAPNIYRVILRYGFM
ETPNLPRALEDLKANGVDFDVMQASYFTSRELLVRSSVPKMSRWRMSLFLLMARNATPATEFFRIPPDRVVELGVRLAI

Sequences:

>Translated_639_residues
MADVPTKITEFGADQHEHAANPVGFAALMVVLGVVFGDIGTSPLYALRSTILVVSQHHQIEAWEVMGVESLILWSLILIV
TVKYVLLIMRADHNGEGGIISLMSLAQRVSENTRLKLVLGMTGIAGACLFFGDGLITPAISVLSAVEGLEVSFPAAHDLV
IPVAIMVLIGLFSVQSAGTGKVGTVFGPVMLLWFSMLGILGMLQILRHPGILMAISPIYAVRFIAFHGWLSFIALGSVVL
SVTGAEALYADMGHFGRQPIRYAWLFCVLPCLALNYMGQGALIIATPSALSNPFFLLGPHWMQIPMVILSTMATVIASQA
GISGGFSLCRQLIQLGYLPRMRITHTNKNEEGQIYLPEFNRFLMVGALTLVVAFRSSDALASAYGIAVTGTFMCTCVLAM
VAFRRLYHWSRAAAAFTFGGFFVMDSIFFASNALKIPQGGWVPVLLGIALTLMMTTWKRGRGLIMNRQKLDSLPVNSFLA
RLPQSRTIRVPGTAVFMTATPEFVPTCLLHNLKHNKVLHEHVLFVTVQTLDQPEATRGHRVALQLLAPNIYRVILRYGFM
ETPNLPRALEDLKANGVDFDVMQASYFTSRELLVRSSVPKMSRWRMSLFLLMARNATPATEFFRIPPDRVVELGVRLAI
>Mature_638_residues
ADVPTKITEFGADQHEHAANPVGFAALMVVLGVVFGDIGTSPLYALRSTILVVSQHHQIEAWEVMGVESLILWSLILIVT
VKYVLLIMRADHNGEGGIISLMSLAQRVSENTRLKLVLGMTGIAGACLFFGDGLITPAISVLSAVEGLEVSFPAAHDLVI
PVAIMVLIGLFSVQSAGTGKVGTVFGPVMLLWFSMLGILGMLQILRHPGILMAISPIYAVRFIAFHGWLSFIALGSVVLS
VTGAEALYADMGHFGRQPIRYAWLFCVLPCLALNYMGQGALIIATPSALSNPFFLLGPHWMQIPMVILSTMATVIASQAG
ISGGFSLCRQLIQLGYLPRMRITHTNKNEEGQIYLPEFNRFLMVGALTLVVAFRSSDALASAYGIAVTGTFMCTCVLAMV
AFRRLYHWSRAAAAFTFGGFFVMDSIFFASNALKIPQGGWVPVLLGIALTLMMTTWKRGRGLIMNRQKLDSLPVNSFLAR
LPQSRTIRVPGTAVFMTATPEFVPTCLLHNLKHNKVLHEHVLFVTVQTLDQPEATRGHRVALQLLAPNIYRVILRYGFME
TPNLPRALEDLKANGVDFDVMQASYFTSRELLVRSSVPKMSRWRMSLFLLMARNATPATEFFRIPPDRVVELGVRLAI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=614, Percent_Identity=46.2540716612378, Blast_Score=545, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 70039; Mature: 69908

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVPTKITEFGADQHEHAANPVGFAALMVVLGVVFGDIGTSPLYALRSTILVVSQHHQI
CCCCCCHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCC
EAWEVMGVESLILWSLILIVTVKYVLLIMRADHNGEGGIISLMSLAQRVSENTRLKLVLG
CHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
MTGIAGACLFFGDGLITPAISVLSAVEGLEVSFPAAHDLVIPVAIMVLIGLFSVQSAGTG
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
KVGTVFGPVMLLWFSMLGILGMLQILRHPGILMAISPIYAVRFIAFHGWLSFIALGSVVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTGAEALYADMGHFGRQPIRYAWLFCVLPCLALNYMGQGALIIATPSALSNPFFLLGPH
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEECCH
WMQIPMVILSTMATVIASQAGISGGFSLCRQLIQLGYLPRMRITHTNKNEEGQIYLPEFN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHH
RFLMVGALTLVVAFRSSDALASAYGIAVTGTFMCTCVLAMVAFRRLYHWSRAAAAFTFGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVMDSIFFASNALKIPQGGWVPVLLGIALTLMMTTWKRGRGLIMNRQKLDSLPVNSFLA
HHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCHHHHHH
RLPQSRTIRVPGTAVFMTATPEFVPTCLLHNLKHNKVLHEHVLFVTVQTLDQPEATRGHR
HCCCCCEEECCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCHH
VALQLLAPNIYRVILRYGFMETPNLPRALEDLKANGVDFDVMQASYFTSRELLVRSSVPK
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
MSRWRMSLFLLMARNATPATEFFRIPPDRVVELGVRLAI
HHHHHHHHHHHHHCCCCCHHHEEECCHHHHHHHHHHCCC
>Mature Secondary Structure 
ADVPTKITEFGADQHEHAANPVGFAALMVVLGVVFGDIGTSPLYALRSTILVVSQHHQI
CCCCCHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCC
EAWEVMGVESLILWSLILIVTVKYVLLIMRADHNGEGGIISLMSLAQRVSENTRLKLVLG
CHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEE
MTGIAGACLFFGDGLITPAISVLSAVEGLEVSFPAAHDLVIPVAIMVLIGLFSVQSAGTG
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCC
KVGTVFGPVMLLWFSMLGILGMLQILRHPGILMAISPIYAVRFIAFHGWLSFIALGSVVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
SVTGAEALYADMGHFGRQPIRYAWLFCVLPCLALNYMGQGALIIATPSALSNPFFLLGPH
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCEEEECCH
WMQIPMVILSTMATVIASQAGISGGFSLCRQLIQLGYLPRMRITHTNKNEEGQIYLPEFN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCHH
RFLMVGALTLVVAFRSSDALASAYGIAVTGTFMCTCVLAMVAFRRLYHWSRAAAAFTFGG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVMDSIFFASNALKIPQGGWVPVLLGIALTLMMTTWKRGRGLIMNRQKLDSLPVNSFLA
HHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCHHHHHH
RLPQSRTIRVPGTAVFMTATPEFVPTCLLHNLKHNKVLHEHVLFVTVQTLDQPEATRGHR
HCCCCCEEECCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCCCCCCCHH
VALQLLAPNIYRVILRYGFMETPNLPRALEDLKANGVDFDVMQASYFTSRELLVRSSVPK
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCH
MSRWRMSLFLLMARNATPATEFFRIPPDRVVELGVRLAI
HHHHHHHHHHHHHCCCCCHHHEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA