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The map label for this gene is mreB [H]

Identifier: 162148120

GI number: 162148120

Start: 2405059

End: 2406192

Strand: Reverse

Name: mreB [H]

Synonym: GDI_2337

Alternate gene names: 162148120

Gene position: 2406192-2405059 (Counterclockwise)

Preceding gene: 162148122

Following gene: 162148119

Centisome position: 61.01

GC content: 65.87

Gene sequence:

>1134_bases
GTGCGAGGCGACGTGTGGCTGTCGGCACGTCGCGCAACCCCGGCCGGGATGATCTGCCATAGTCGTGCTTGTTGTCGGGA
GTTCTGGATGTTTGCTCGTCTGCTGGGTCTCTTGTCGGCCGACATGGCCATCGACCTCGGCACGGCCAATACCCTTGTCT
ATGTCAAGGGGCGTGGCGTCGTCCTGAATGAACCCTCGGTGGTCGCCATCGCCGAGGTACGCGGCAAGAAGATGGTGCTG
GCGGTGGGCGAGGAAGCCAAGCAGATGGTCGGGCGCACGCCCGGCAACATCACCGCCATCCGCCCCCTGCGCGATGGCGT
CATCGCCGATTTCGAGGTCGCGGAGGAAATGATCAAGCATTTCATCCGCAAGGTGCATAACCGGCGGATGTTCGCCAGCC
CGCTGATCATCGTCTGCGTGCCCTCCGGCTCGACCGCCGTCGAGCGCCGGGCGATCCAGGAAAGCGCCGAGAGCGCGGGC
GCGCGCAAGGTCTTCCTGATCGAGGAGCCGATGGCGGCGGCGATCGGCGCCGGCCTGCCGGTCACCGAGCCGTCGGGCAG
CATGATCGTCGATATCGGCGGCGGTACGACCGAGGTCGCGGTGATTTCGCTGGGCGGTATCGTCTATGCGCGCTCGGCCC
GGGTCGGCGGCGACAAGATGGACGAGGCCATCATCTCGTATATCCGGCGTAACCATAACCTGCTGATCGGTGAAAGCTCG
GCCGAGCGGATCAAGATCGAACTGGGATCGGCCCTGCCGCCCGACGACCTGGAAGATTACGGCGGCTGGCGCGAGGTCAA
GGGACGCGACCTGATCAACGGCGTCCCGCGCGAGGTCGTGGTGTCGCAGGCGCAGATCGCCGAGAGCCTGGCCGAGCCGG
TCAGCCAGATCGTGGACGCGGTGACCACCGCGCTGGAAAACACGCCCCCAGAACTGGCCGCCGACATCGTGGACAAGGGA
ATCGTGCTGACCGGCGGCGGCGCGCTGCTCTATCGGCTGGACGAGGTACTGCGCCGCGCGACCGGCCTGCCGGTGACGGT
GGGCGAGGACGCATTGTCCTGCGTGGCGCTGGGGACTGGACGCGCCCTCGAAGAAATGAAACGTTTGAAGAATGTCCTGA
CCAGCATGTACTGA

Upstream 100 bases:

>100_bases
GGATCGGCGGGGCGGCATGGAAATGCACGATTTAATGTCCGTGGCCCTTGCCCGTCTCTTCCAGCCCCGGTAAGCCCACG
GCCTGATCCTGTGGGCTTGT

Downstream 100 bases:

>100_bases
CGGCAGGCGAAAACAGGCGGTTCGGCCAGGCGGTGGCCGGCCCGCGCAGGGACAGGCAAGGGGGCCGGGGCGATGAACGT
CCGGCGGGGCGGCTGTAGAA

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRGDVWLSARRATPAGMICHSRACCREFWMFARLLGLLSADMAIDLGTANTLVYVKGRGVVLNEPSVVAIAEVRGKKMVL
AVGEEAKQMVGRTPGNITAIRPLRDGVIADFEVAEEMIKHFIRKVHNRRMFASPLIIVCVPSGSTAVERRAIQESAESAG
ARKVFLIEEPMAAAIGAGLPVTEPSGSMIVDIGGGTTEVAVISLGGIVYARSARVGGDKMDEAIISYIRRNHNLLIGESS
AERIKIELGSALPPDDLEDYGGWREVKGRDLINGVPREVVVSQAQIAESLAEPVSQIVDAVTTALENTPPELAADIVDKG
IVLTGGGALLYRLDEVLRRATGLPVTVGEDALSCVALGTGRALEEMKRLKNVLTSMY

Sequences:

>Translated_377_residues
MRGDVWLSARRATPAGMICHSRACCREFWMFARLLGLLSADMAIDLGTANTLVYVKGRGVVLNEPSVVAIAEVRGKKMVL
AVGEEAKQMVGRTPGNITAIRPLRDGVIADFEVAEEMIKHFIRKVHNRRMFASPLIIVCVPSGSTAVERRAIQESAESAG
ARKVFLIEEPMAAAIGAGLPVTEPSGSMIVDIGGGTTEVAVISLGGIVYARSARVGGDKMDEAIISYIRRNHNLLIGESS
AERIKIELGSALPPDDLEDYGGWREVKGRDLINGVPREVVVSQAQIAESLAEPVSQIVDAVTTALENTPPELAADIVDKG
IVLTGGGALLYRLDEVLRRATGLPVTVGEDALSCVALGTGRALEEMKRLKNVLTSMY
>Mature_377_residues
MRGDVWLSARRATPAGMICHSRACCREFWMFARLLGLLSADMAIDLGTANTLVYVKGRGVVLNEPSVVAIAEVRGKKMVL
AVGEEAKQMVGRTPGNITAIRPLRDGVIADFEVAEEMIKHFIRKVHNRRMFASPLIIVCVPSGSTAVERRAIQESAESAG
ARKVFLIEEPMAAAIGAGLPVTEPSGSMIVDIGGGTTEVAVISLGGIVYARSARVGGDKMDEAIISYIRRNHNLLIGESS
AERIKIELGSALPPDDLEDYGGWREVKGRDLINGVPREVVVSQAQIAESLAEPVSQIVDAVTTALENTPPELAADIVDKG
IVLTGGGALLYRLDEVLRRATGLPVTVGEDALSCVALGTGRALEEMKRLKNVLTSMY

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=338, Percent_Identity=63.0177514792899, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 40296; Mature: 40296

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGDVWLSARRATPAGMICHSRACCREFWMFARLLGLLSADMAIDLGTANTLVYVKGRGV
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCEE
VLNEPSVVAIAEVRGKKMVLAVGEEAKQMVGRTPGNITAIRPLRDGVIADFEVAEEMIKH
EECCCCEEEEEECCCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCEECHHHHHHHHHH
FIRKVHNRRMFASPLIIVCVPSGSTAVERRAIQESAESAGARKVFLIEEPMAAAIGAGLP
HHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCC
VTEPSGSMIVDIGGGTTEVAVISLGGIVYARSARVGGDKMDEAIISYIRRNHNLLIGESS
CCCCCCCEEEEECCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCC
AERIKIELGSALPPDDLEDYGGWREVKGRDLINGVPREVVVSQAQIAESLAEPVSQIVDA
CCEEEEEECCCCCCCCHHHCCCCEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTTALENTPPELAADIVDKGIVLTGGGALLYRLDEVLRRATGLPVTVGEDALSCVALGTG
HHHHHCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEECCHHHHEEEECCC
RALEEMKRLKNVLTSMY
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRGDVWLSARRATPAGMICHSRACCREFWMFARLLGLLSADMAIDLGTANTLVYVKGRGV
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCEE
VLNEPSVVAIAEVRGKKMVLAVGEEAKQMVGRTPGNITAIRPLRDGVIADFEVAEEMIKH
EECCCCEEEEEECCCCEEEEEECHHHHHHHCCCCCCEEEEEECCCCCEECHHHHHHHHHH
FIRKVHNRRMFASPLIIVCVPSGSTAVERRAIQESAESAGARKVFLIEEPMAAAIGAGLP
HHHHHHCCCEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCC
VTEPSGSMIVDIGGGTTEVAVISLGGIVYARSARVGGDKMDEAIISYIRRNHNLLIGESS
CCCCCCCEEEEECCCCEEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCC
AERIKIELGSALPPDDLEDYGGWREVKGRDLINGVPREVVVSQAQIAESLAEPVSQIVDA
CCEEEEEECCCCCCCCHHHCCCCEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTTALENTPPELAADIVDKGIVLTGGGALLYRLDEVLRRATGLPVTVGEDALSCVALGTG
HHHHHCCCCHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEECCHHHHEEEECCC
RALEEMKRLKNVLTSMY
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]