BacMap

Definition	Gluconacetobacter diazotrophicus PAl 5 chromosome, complete genome.
Accession	NC_010125
Length	3,944,163

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The map label for this gene is ppi [H]

Identifier: 162148108

GI number: 162148108

Start: 2391559

End: 2392044

Strand: Direct

Name: ppi [H]

Synonym: GDI_2325

Alternate gene names: 162148108

Gene position: 2391559-2392044 (Clockwise)

Preceding gene: 162148107

Following gene: 162148114

Centisome position: 60.64

GC content: 66.87

Gene sequence:

>486_bases
ATGTCTGATACCGCACCGAAAGCCGACCTGATCGACCTGGAACTGAAGACGGGCCGTGTGGTCATTCAGTTGCGTCCCGA
CCTGGCGCCGCTGGCGGCCGAGCGGATCCGTACGCTGGCGGCCGAGGGCTTCTACGACAACACGCCCTTCCACCGCGTCA
TTCACGGCTTCATGGCCCAGGGCGGCGACCCGACCGGCACGGGCACCAGCGGCAGCCACCTGCCCGACCTGAAGGCCGAA
TTCACCCGCGCCGCGAAGTTCGAGCGCGGCACCATCGGCATGGCCCGCACGATGAACCCGGACAGCGCGAACAGCCAGTT
CTTCATCATGTTCGAGCCCTCGCCCCACCTGGACGGCCAGTACACGATCGTCGGCCAGGTGGTCGAAGGCATGGAGCATA
TCGACCAGATCAAGCGCGGCGCGGGCCAGAGCGGCACGGTGCAGGACCCGGACCGCATCATTTCCATGCGTCCCGCCGCA
GCCTGA

Upstream 100 bases:

>100_bases
CCCTTCACGCGCCGGCATGTCCTGGCGCGGCTGGAGGGATAACGCACGGTCCGGGCACGGCATGCCGTGCCACGGGCCTT
TCAGCACTGGAACATGAACG

Downstream 100 bases:

>100_bases
CACGCGTCTGCCGGTTGACTTGACCGGCCGAAACCGTTACCCGGGGCCGCACCGCACAGGCGGCCCTGGTGAGCCGGTAG
CTCAGTCGGTAGAGCATTCG

Product: peptidyl-prolyl cis-trans isomerase B

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSDTAPKADLIDLELKTGRVVIQLRPDLAPLAAERIRTLAAEGFYDNTPFHRVIHGFMAQGGDPTGTGTSGSHLPDLKAE
FTRAAKFERGTIGMARTMNPDSANSQFFIMFEPSPHLDGQYTIVGQVVEGMEHIDQIKRGAGQSGTVQDPDRIISMRPAA
A

Sequences:

>Translated_161_residues
MSDTAPKADLIDLELKTGRVVIQLRPDLAPLAAERIRTLAAEGFYDNTPFHRVIHGFMAQGGDPTGTGTSGSHLPDLKAE
FTRAAKFERGTIGMARTMNPDSANSQFFIMFEPSPHLDGQYTIVGQVVEGMEHIDQIKRGAGQSGTVQDPDRIISMRPAA
A
>Mature_160_residues
SDTAPKADLIDLELKTGRVVIQLRPDLAPLAAERIRTLAAEGFYDNTPFHRVIHGFMAQGGDPTGTGTSGSHLPDLKAEF
TRAAKFERGTIGMARTMNPDSANSQFFIMFEPSPHLDGQYTIVGQVVEGMEHIDQIKRGAGQSGTVQDPDRIISMRPAAA

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI19557636, Length=132, Percent_Identity=35.6060606060606, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI7706339, Length=137, Percent_Identity=38.6861313868613, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI64276486, Length=119, Percent_Identity=39.4957983193277, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI24308049, Length=123, Percent_Identity=36.5853658536585, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI5031987, Length=137, Percent_Identity=37.956204379562, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI4826932, Length=130, Percent_Identity=33.8461538461538, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI45439316, Length=128, Percent_Identity=34.375, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI10863927, Length=134, Percent_Identity=35.8208955223881, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI5174637, Length=134, Percent_Identity=33.5820895522388, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI303305009, Length=127, Percent_Identity=34.6456692913386, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI4505991, Length=131, Percent_Identity=36.6412213740458, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI4758950, Length=131, Percent_Identity=36.6412213740458, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI256017253, Length=129, Percent_Identity=36.4341085271318, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI221139811, Length=129, Percent_Identity=36.4341085271318, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI256017251, Length=129, Percent_Identity=36.4341085271318, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI178057341, Length=129, Percent_Identity=36.4341085271318, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI42560244, Length=134, Percent_Identity=32.8358208955224, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI310129267, Length=134, Percent_Identity=33.5820895522388, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI310120620, Length=134, Percent_Identity=33.5820895522388, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI150418007, Length=136, Percent_Identity=32.3529411764706, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1789763, Length=132, Percent_Identity=40.1515151515151, Blast_Score=88, Evalue=2e-19,
Organism=Escherichia coli, GI1786736, Length=151, Percent_Identity=38.4105960264901, Blast_Score=88, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71980594, Length=131, Percent_Identity=38.1679389312977, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71980590, Length=131, Percent_Identity=38.1679389312977, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17539496, Length=141, Percent_Identity=35.4609929078014, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17532641, Length=154, Percent_Identity=35.0649350649351, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17539498, Length=145, Percent_Identity=39.3103448275862, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71997782, Length=123, Percent_Identity=39.0243902439024, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506311, Length=144, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566266, Length=143, Percent_Identity=33.5664335664336, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551284, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17551282, Length=132, Percent_Identity=34.0909090909091, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565860, Length=141, Percent_Identity=34.0425531914894, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17552782, Length=151, Percent_Identity=30.4635761589404, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559074, Length=142, Percent_Identity=32.3943661971831, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17552780, Length=145, Percent_Identity=33.7931034482759, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506307, Length=145, Percent_Identity=35.8620689655172, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320359, Length=140, Percent_Identity=38.5714285714286, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323562, Length=139, Percent_Identity=34.5323741007194, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321848, Length=137, Percent_Identity=38.6861313868613, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323246, Length=130, Percent_Identity=35.3846153846154, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17986117, Length=140, Percent_Identity=37.1428571428571, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24652460, Length=132, Percent_Identity=35.6060606060606, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922376, Length=138, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24664125, Length=139, Percent_Identity=37.410071942446, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357783, Length=139, Percent_Identity=37.410071942446, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357249, Length=125, Percent_Identity=37.6, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45549139, Length=137, Percent_Identity=37.956204379562, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17647301, Length=135, Percent_Identity=35.5555555555556, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24661775, Length=155, Percent_Identity=30.9677419354839, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355237, Length=155, Percent_Identity=30.9677419354839, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24661771, Length=155, Percent_Identity=30.9677419354839, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650807, Length=137, Percent_Identity=35.036496350365, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20130249, Length=131, Percent_Identity=34.3511450381679, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19922912, Length=149, Percent_Identity=38.255033557047, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17436; Mature: 17305

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTAPKADLIDLELKTGRVVIQLRPDLAPLAAERIRTLAAEGFYDNTPFHRVIHGFMAQ
CCCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GGDPTGTGTSGSHLPDLKAEFTRAAKFERGTIGMARTMNPDSANSQFFIMFEPSPHLDGQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCC
YTIVGQVVEGMEHIDQIKRGAGQSGTVQDPDRIISMRPAAA
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCC
>Mature Secondary Structure 
SDTAPKADLIDLELKTGRVVIQLRPDLAPLAAERIRTLAAEGFYDNTPFHRVIHGFMAQ
CCCCCCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
GGDPTGTGTSGSHLPDLKAEFTRAAKFERGTIGMARTMNPDSANSQFFIMFEPSPHLDGQ
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCC
YTIVGQVVEGMEHIDQIKRGAGQSGTVQDPDRIISMRPAAA
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA