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The map label for this gene is erpA2 [H]

Identifier: 162148011

GI number: 162148011

Start: 2283081

End: 2283479

Strand: Direct

Name: erpA2 [H]

Synonym: GDI_2227

Alternate gene names: 162148011

Gene position: 2283081-2283479 (Clockwise)

Preceding gene: 162148002

Following gene: 162148012

Centisome position: 57.89

GC content: 67.67

Gene sequence:

>399_bases
ATGTTGCCCGCACGAGGATGGTATCCCATGGACACAGCTTCCACCCCTACCCCCGATACGCGCTTTCGCGTCTCCCCCCA
GGCCGTCACCCGGCTGGAGGAAATCGTGGCGGCCGAGCCGGCCCCGGAGGGCGCCGCCGCCCCCGGCCTGCGCGTCAGCG
TGCTGGCCGGTGGGTGCAACGGCTTCCAGTACAGCTTCGCCCTGGACGGCGAGCGCCGCGCCGACGACGTTCTCATTCCC
GCCGGGCAGTCGCATGTGGTGGTCGATCCGGCCAGCATGGACCTGCTGGACGGGGCGGAACTGCATTTCAACGATTCGCT
GATGGGCGCGCATTTCACCATCCGCAACCCCAATGCCACGTCGTCCTGCGGGTGCGGCACCAGCTTTTCCATCGATTGA

Upstream 100 bases:

>100_bases
TAGGGTGCGATGCTCATATATACCCTCACTCCCGGATAGGCGCCCCTGTCGATACCCCGCCCGGCGCCGCAAGACCAGCA
CGGGCTGCGGCCTTGGCCGC

Downstream 100 bases:

>100_bases
GCGTCCGGCCGCATTGATGAAAATCGCAAGCTGGAACGTCAATTCGGTCCGCCAGCGCCAGGCGCATGTCCTGGACTGGC
TGGAGCGGGAAAAGCCCGAC

Product: iron-sulfur assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MLPARGWYPMDTASTPTPDTRFRVSPQAVTRLEEIVAAEPAPEGAAAPGLRVSVLAGGCNGFQYSFALDGERRADDVLIP
AGQSHVVVDPASMDLLDGAELHFNDSLMGAHFTIRNPNATSSCGCGTSFSID

Sequences:

>Translated_132_residues
MLPARGWYPMDTASTPTPDTRFRVSPQAVTRLEEIVAAEPAPEGAAAPGLRVSVLAGGCNGFQYSFALDGERRADDVLIP
AGQSHVVVDPASMDLLDGAELHFNDSLMGAHFTIRNPNATSSCGCGTSFSID
>Mature_132_residues
MLPARGWYPMDTASTPTPDTRFRVSPQAVTRLEEIVAAEPAPEGAAAPGLRVSVLAGGCNGFQYSFALDGERRADDVLIP
AGQSHVVVDPASMDLLDGAELHFNDSLMGAHFTIRNPNATSSCGCGTSFSID

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=124, Percent_Identity=37.9032258064516, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786351, Length=104, Percent_Identity=39.4230769230769, Blast_Score=85, Evalue=1e-18,
Organism=Escherichia coli, GI1787974, Length=108, Percent_Identity=31.4814814814815, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1788877, Length=83, Percent_Identity=36.144578313253, Blast_Score=61, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=115, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325324, Length=138, Percent_Identity=31.1594202898551, Blast_Score=74, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24649697, Length=122, Percent_Identity=37.7049180327869, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13880; Mature: 13880

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPARGWYPMDTASTPTPDTRFRVSPQAVTRLEEIVAAEPAPEGAAAPGLRVSVLAGGCN
CCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
GFQYSFALDGERRADDVLIPAGQSHVVVDPASMDLLDGAELHFNDSLMGAHFTIRNPNAT
CEEEEEEECCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEEECCCEECEEEEEECCCCC
SSCGCGTSFSID
CCCCCCCEECCC
>Mature Secondary Structure
MLPARGWYPMDTASTPTPDTRFRVSPQAVTRLEEIVAAEPAPEGAAAPGLRVSVLAGGCN
CCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
GFQYSFALDGERRADDVLIPAGQSHVVVDPASMDLLDGAELHFNDSLMGAHFTIRNPNAT
CEEEEEEECCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEEECCCEECEEEEEECCCCC
SSCGCGTSFSID
CCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA