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The map label for this gene is yccK [H]

Identifier: 162147974

GI number: 162147974

Start: 2242880

End: 2243968

Strand: Direct

Name: yccK [H]

Synonym: GDI_2190

Alternate gene names: 162147974

Gene position: 2242880-2243968 (Clockwise)

Preceding gene: 162147973

Following gene: 162147975

Centisome position: 56.87

GC content: 67.22

Gene sequence:

>1089_bases
ATGACGAACAGGACCCGGCCCGCGCACCGGCGCTGTCCGACCATTGTCCGGTCTCGGTCAGGCTGGAAATGCCTTAAAGT
CCGCCTCTGGACATGCGCGTGTATGATTCGGAAAGGATATCATGGGATGGAACAGCGTCATCTCGGCCGGTCCGGCCTTC
GCGTCTCGGCGGTGGGACTGGGGTGCAACAATCTCGGCGGCCGGATCGGGCTGGAAGAATCGCGCATGGTGGTGCACCAG
GCGCTGGACAGCGGCATCACCCTGTTCGACGTCGCCGATGTCTATGGCCGGCGCGAATCCCATTGCGGCGCGTCCGAGGA
AGTGTTGGGCGCGATCCTGGGCTCGCGTCGCGAGGACATCGTCCTGGCGACCAAGTTCGGCATGCCCATGGCCGCCGACG
GCAGCATGCAGGGGGCATCCCGCCGCTATATCCGCCAGGCGGTCGAGGCCAGCCTGACGCGCCTGCGCACCGACCGCATC
GACCTCTACCAGGTCCATGTCCCCGACCCGGACACCCCGATCGACGAGACGCTGCGCGCGCTGGACGACCTGATCCGTGA
CGGCAAGGTCCTGTATGCCGGCTGTTCCAACTTTCCCGCATGGCAAGTCGCGGACGCCCATCACGTCGCGCGCGCGGGCG
GGTTTTCGGGCTTCATTTCCTGCCAGGACGAACTGTCGCTGCTGGCGCGGGACGCGCTACGCGAACTGGTGCCGGCCATG
CGCCGGTACGGCCTGGGATTGCTGCCCTACTTCCCGCTGGCCAGCGGCGTACTGACGGGCAAATACCATCGCGACATTCC
GCCGCCCCCCGGCAGCCGGCTGAGCGAATGGACCCACCTGCGCGATCGCTACCTGACCGACACCAACTGGACGATCCTGG
ACGGGCTGGGTTCGGTGGCCAGGGCGCATGGACGCACGCTGACGGAACTGGCCTTCGGCTGGCTGCTGTCGCATGACGTG
GTGGGGTCGGTCATCGCCGGCGCCACCCGCCCGAATCAGGTGATTGAAAACGTCGCCGCCGCGACCCGCCCCCTGACGCC
GGAGGAATGCGACGCGATCACCGCCATCCTGCCCGACCATGCGCGATGA

Upstream 100 bases:

>100_bases
GCCAGCCCGTGCTGGGGAGGCACCTATTTCATCGACCATCTGCTGCTGGGCAACCAGGCGCGCGGGTGGCTGCGGCCGGA
CAGCCTGCGGGTCCTGACCT

Downstream 100 bases:

>100_bases
ACCGCCCGGGTTGCGCTGGCCGTCGCGCTGGCCGTCCATCGCGCTGGATTCGGGACTGACCGTACGGGTCGCGGGCCACA
TGCCCGACCTGCCCGCCCCC

Product: oxidoreductase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTNRTRPAHRRCPTIVRSRSGWKCLKVRLWTCACMIRKGYHGMEQRHLGRSGLRVSAVGLGCNNLGGRIGLEESRMVVHQ
ALDSGITLFDVADVYGRRESHCGASEEVLGAILGSRREDIVLATKFGMPMAADGSMQGASRRYIRQAVEASLTRLRTDRI
DLYQVHVPDPDTPIDETLRALDDLIRDGKVLYAGCSNFPAWQVADAHHVARAGGFSGFISCQDELSLLARDALRELVPAM
RRYGLGLLPYFPLASGVLTGKYHRDIPPPPGSRLSEWTHLRDRYLTDTNWTILDGLGSVARAHGRTLTELAFGWLLSHDV
VGSVIAGATRPNQVIENVAAATRPLTPEECDAITAILPDHAR

Sequences:

>Translated_362_residues
MTNRTRPAHRRCPTIVRSRSGWKCLKVRLWTCACMIRKGYHGMEQRHLGRSGLRVSAVGLGCNNLGGRIGLEESRMVVHQ
ALDSGITLFDVADVYGRRESHCGASEEVLGAILGSRREDIVLATKFGMPMAADGSMQGASRRYIRQAVEASLTRLRTDRI
DLYQVHVPDPDTPIDETLRALDDLIRDGKVLYAGCSNFPAWQVADAHHVARAGGFSGFISCQDELSLLARDALRELVPAM
RRYGLGLLPYFPLASGVLTGKYHRDIPPPPGSRLSEWTHLRDRYLTDTNWTILDGLGSVARAHGRTLTELAFGWLLSHDV
VGSVIAGATRPNQVIENVAAATRPLTPEECDAITAILPDHAR
>Mature_361_residues
TNRTRPAHRRCPTIVRSRSGWKCLKVRLWTCACMIRKGYHGMEQRHLGRSGLRVSAVGLGCNNLGGRIGLEESRMVVHQA
LDSGITLFDVADVYGRRESHCGASEEVLGAILGSRREDIVLATKFGMPMAADGSMQGASRRYIRQAVEASLTRLRTDRID
LYQVHVPDPDTPIDETLRALDDLIRDGKVLYAGCSNFPAWQVADAHHVARAGGFSGFISCQDELSLLARDALRELVPAMR
RYGLGLLPYFPLASGVLTGKYHRDIPPPPGSRLSEWTHLRDRYLTDTNWTILDGLGSVARAHGRTLTELAFGWLLSHDVV
GSVIAGATRPNQVIENVAAATRPLTPEECDAITAILPDHAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=312, Percent_Identity=35.2564102564103, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI4504825, Length=303, Percent_Identity=35.3135313531353, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=33.5504885993485, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=33.5504885993485, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI27436966, Length=307, Percent_Identity=33.5504885993485, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=31.8042813455657, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI223718702, Length=320, Percent_Identity=30, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI41152114, Length=313, Percent_Identity=29.7124600638978, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI41327764, Length=317, Percent_Identity=30.2839116719243, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI223718708, Length=166, Percent_Identity=31.9277108433735, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=33.7461300309598, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789375, Length=311, Percent_Identity=33.4405144694534, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=28.9085545722714, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=31.4814814814815, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788081, Length=318, Percent_Identity=25.7861635220126, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=335, Percent_Identity=29.8507462686567, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=27.6923076923077, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6319958, Length=302, Percent_Identity=28.476821192053, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=269, Percent_Identity=29.7397769516729, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=29.6, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24640980, Length=323, Percent_Identity=26.9349845201238, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45549126, Length=323, Percent_Identity=26.9349845201238, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24646155, Length=177, Percent_Identity=38.4180790960452, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646159, Length=176, Percent_Identity=33.5227272727273, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39836; Mature: 39705

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRTRPAHRRCPTIVRSRSGWKCLKVRLWTCACMIRKGYHGMEQRHLGRSGLRVSAVGL
CCCCCCCHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEC
GCNNLGGRIGLEESRMVVHQALDSGITLFDVADVYGRRESHCGASEEVLGAILGSRREDI
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCE
VLATKFGMPMAADGSMQGASRRYIRQAVEASLTRLRTDRIDLYQVHVPDPDTPIDETLRA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHH
LDDLIRDGKVLYAGCSNFPAWQVADAHHVARAGGFSGFISCQDELSLLARDALRELVPAM
HHHHHHCCCEEEEECCCCCCCEECCHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHH
RRYGLGLLPYFPLASGVLTGKYHRDIPPPPGSRLSEWTHLRDRYLTDTNWTILDGLGSVA
HHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RAHGRTLTELAFGWLLSHDVVGSVIAGATRPNQVIENVAAATRPLTPEECDAITAILPDH
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AR
CC
>Mature Secondary Structure 
TNRTRPAHRRCPTIVRSRSGWKCLKVRLWTCACMIRKGYHGMEQRHLGRSGLRVSAVGL
CCCCCCHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEEC
GCNNLGGRIGLEESRMVVHQALDSGITLFDVADVYGRRESHCGASEEVLGAILGSRREDI
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCE
VLATKFGMPMAADGSMQGASRRYIRQAVEASLTRLRTDRIDLYQVHVPDPDTPIDETLRA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHH
LDDLIRDGKVLYAGCSNFPAWQVADAHHVARAGGFSGFISCQDELSLLARDALRELVPAM
HHHHHHCCCEEEEECCCCCCCEECCHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHH
RRYGLGLLPYFPLASGVLTGKYHRDIPPPPGSRLSEWTHLRDRYLTDTNWTILDGLGSVA
HHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RAHGRTLTELAFGWLLSHDVVGSVIAGATRPNQVIENVAAATRPLTPEECDAITAILPDH
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
AR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]