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The map label for this gene is ctaD [H]

Identifier: 162147885

GI number: 162147885

Start: 2149428

End: 2150840

Strand: Reverse

Name: ctaD [H]

Synonym: GDI_2101

Alternate gene names: 162147885

Gene position: 2150840-2149428 (Counterclockwise)

Preceding gene: 162147886

Following gene: 162147884

Centisome position: 54.53

GC content: 71.41

Gene sequence:

>1413_bases
TTGAGGAAGACCGCCTGGCGCGGTCCGTTATCGCAGGAGAAGAGGCGCATGCCGACTGACGGGCAGGTTCGGGCAGGGAT
CGGAACCGGTGGCTTCCCGGCGCGATGGAACCGCGCATGCGGCCACAAGACGGTCGGAAGCCTGTATCTGGTCCTGGCCG
TGCTGGCGGGGCTGGCGGGCGGCGGCCTCGCGCTTCTGCTGCAGGTCGGTCAGGCTGGGCTGGACGGGGCCGCCTCCGCC
CCGTGGCACCGCATGACGATCGATCACGGCGCGCTGATGATCCTGTTCTGTGCCCTGCCGGCCCTGACCGGCGGGTTCGG
GTCCTGGTTCGTGCCGCTGCTGCTGGGGGCGCCGGATATGGCGTTCCGCCGGCTGAACCTGCTGTGCTGGGCCGGCCTGG
CCGTCAGCTTCGCGCTGGTCCTGTCCGGGATGGCGACGGCGCCGGGCATGCTGCTGTGGTGTGCCGCGATGCTGGGCCTG
TCGATCGACATGGTCGCGACGGTGCTGAACATGCGCCGCCCCGGTATGGCGCTGCGCGACATGCCGCTGTTCGCCTGGGC
GCAGGCGCTGACCGGGATGATGATGGTGATCGTGCTGCCGGTGCTGGCGGCCTCGCTGACGCGCGGCCTGCTGGCCGGTA
CCGGCGGGCGGCAGGCCGAACTGGCGTTGCGCGCCTTTTCGGGTCCCGAAATCGGCCTGTTGCTGCTGCCGGCCGCGGGC
ATCGTATGCCAGGTGGTCGAAACCTTTTCAGGCGTCGCCCTGCGGCTGCGTGGCGCGGCGCTGGGGGCCATGGTCGTCCT
GTCCGTGGGGGGTGCGACCATCTGGGTGCATGACCTGTTCGCTGATGGGCTGGCCGTGCAATCCGTCGTGCGGCCCCTGA
TCGAACAGGCGACGATCGCGGTGCCCATGCTGGTCCTGCTGGCGGCCTGGGGCGCCACCGTCCTGGGCGGGCGGGCGGCT
TTCCGCGTGCCGATGCTGTGGGCCTGCGCCTTTGCTGTGCTGCTGGTCGCGGGGCCGGTCCTGGCGCTGCTGGGCGGTCC
GGCGGCCGGGCATGCCGTGGCGCTGCCGGCCGCGCTGTTCGCGACATTCGCCGGTTTTTATTACTGGATCGGCAAGATGA
CGGGCCGCGCCTGCCCCGAACGGGCCGGCCGGCTGCATGTCGCGCTGGCGGTGGGGGGCAGCATCCTGTTGCTGGCTCCG
CATCAGCCGGCTTTCGTATCGACCGGCGTGGTGCTGCTGGGCCTGTCGATGCTGGCCTTCGTCGCCGCCATCGCCCTGAC
GCTGGCGGGACGCACGCGTCCGCTGGCCGCGAATTACTGGGGGCCGGGTGCCCGGACCCTGGAATGGACGGTGCCGTCGC
CCGCACCGCGTGACTCCTTCGCCGGTATCCTGGCCCACGGAGCACGGGCGTGA

Upstream 100 bases:

>100_bases
GCCGGCCCGCCGCGTCGGCGGGGCGGGAATGGCGGCCATGCCGGATGCGGGCTCCTCGGGGCTCGTCTTTGCAGGCACGC
TCCGGTAAAATCATCGCGCT

Downstream 100 bases:

>100_bases
GCGGCGCGGCAACCACCGAAGGCGCCGTAACCCGTTTCGACGCCGCTTTGGTCGGAACCGAGGCCCGCGACTGGTTCGCG
CTGCTGAAGCCGCGGGTGAT

Product: cytochrome c oxidase subunit 1

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-beta; Cytochrome c oxidase polypeptide I-beta [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MRKTAWRGPLSQEKRRMPTDGQVRAGIGTGGFPARWNRACGHKTVGSLYLVLAVLAGLAGGGLALLLQVGQAGLDGAASA
PWHRMTIDHGALMILFCALPALTGGFGSWFVPLLLGAPDMAFRRLNLLCWAGLAVSFALVLSGMATAPGMLLWCAAMLGL
SIDMVATVLNMRRPGMALRDMPLFAWAQALTGMMMVIVLPVLAASLTRGLLAGTGGRQAELALRAFSGPEIGLLLLPAAG
IVCQVVETFSGVALRLRGAALGAMVVLSVGGATIWVHDLFADGLAVQSVVRPLIEQATIAVPMLVLLAAWGATVLGGRAA
FRVPMLWACAFAVLLVAGPVLALLGGPAAGHAVALPAALFATFAGFYYWIGKMTGRACPERAGRLHVALAVGGSILLLAP
HQPAFVSTGVVLLGLSMLAFVAAIALTLAGRTRPLAANYWGPGARTLEWTVPSPAPRDSFAGILAHGARA

Sequences:

>Translated_470_residues
MRKTAWRGPLSQEKRRMPTDGQVRAGIGTGGFPARWNRACGHKTVGSLYLVLAVLAGLAGGGLALLLQVGQAGLDGAASA
PWHRMTIDHGALMILFCALPALTGGFGSWFVPLLLGAPDMAFRRLNLLCWAGLAVSFALVLSGMATAPGMLLWCAAMLGL
SIDMVATVLNMRRPGMALRDMPLFAWAQALTGMMMVIVLPVLAASLTRGLLAGTGGRQAELALRAFSGPEIGLLLLPAAG
IVCQVVETFSGVALRLRGAALGAMVVLSVGGATIWVHDLFADGLAVQSVVRPLIEQATIAVPMLVLLAAWGATVLGGRAA
FRVPMLWACAFAVLLVAGPVLALLGGPAAGHAVALPAALFATFAGFYYWIGKMTGRACPERAGRLHVALAVGGSILLLAP
HQPAFVSTGVVLLGLSMLAFVAAIALTLAGRTRPLAANYWGPGARTLEWTVPSPAPRDSFAGILAHGARA
>Mature_470_residues
MRKTAWRGPLSQEKRRMPTDGQVRAGIGTGGFPARWNRACGHKTVGSLYLVLAVLAGLAGGGLALLLQVGQAGLDGAASA
PWHRMTIDHGALMILFCALPALTGGFGSWFVPLLLGAPDMAFRRLNLLCWAGLAVSFALVLSGMATAPGMLLWCAAMLGL
SIDMVATVLNMRRPGMALRDMPLFAWAQALTGMMMVIVLPVLAASLTRGLLAGTGGRQAELALRAFSGPEIGLLLLPAAG
IVCQVVETFSGVALRLRGAALGAMVVLSVGGATIWVHDLFADGLAVQSVVRPLIEQATIAVPMLVLLAAWGATVLGGRAA
FRVPMLWACAFAVLLVAGPVLALLGGPAAGHAVALPAALFATFAGFYYWIGKMTGRACPERAGRLHVALAVGGSILLLAP
HQPAFVSTGVVLLGLSMLAFVAAIALTLAGRTRPLAANYWGPGARTLEWTVPSPAPRDSFAGILAHGARA

Specific function: Subunit I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). This cytochrome c oxidase shows proton pump activity across th

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=435, Percent_Identity=26.4367816091954, Blast_Score=140, Evalue=4e-33,
Organism=Escherichia coli, GI1786634, Length=512, Percent_Identity=27.5390625, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6226519, Length=428, Percent_Identity=27.803738317757, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=28, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6226523, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 48547; Mature: 48547

Theoretical pI: Translated: 11.38; Mature: 11.38

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTAWRGPLSQEKRRMPTDGQVRAGIGTGGFPARWNRACGHKTVGSLYLVLAVLAGLAG
CCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCC
GGLALLLQVGQAGLDGAASAPWHRMTIDHGALMILFCALPALTGGFGSWFVPLLLGAPDM
CHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
AFRRLNLLCWAGLAVSFALVLSGMATAPGMLLWCAAMLGLSIDMVATVLNMRRPGMALRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHC
MPLFAWAQALTGMMMVIVLPVLAASLTRGLLAGTGGRQAELALRAFSGPEIGLLLLPAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCEEEECHHH
IVCQVVETFSGVALRLRGAALGAMVVLSVGGATIWVHDLFADGLAVQSVVRPLIEQATIA
HHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VPMLVLLAAWGATVLGGRAAFRVPMLWACAFAVLLVAGPVLALLGGPAAGHAVALPAALF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ATFAGFYYWIGKMTGRACPERAGRLHVALAVGGSILLLAPHQPAFVSTGVVLLGLSMLAF
HHHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHH
VAAIALTLAGRTRPLAANYWGPGARTLEWTVPSPAPRDSFAGILAHGARA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRKTAWRGPLSQEKRRMPTDGQVRAGIGTGGFPARWNRACGHKTVGSLYLVLAVLAGLAG
CCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCC
GGLALLLQVGQAGLDGAASAPWHRMTIDHGALMILFCALPALTGGFGSWFVPLLLGAPDM
CHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
AFRRLNLLCWAGLAVSFALVLSGMATAPGMLLWCAAMLGLSIDMVATVLNMRRPGMALRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHC
MPLFAWAQALTGMMMVIVLPVLAASLTRGLLAGTGGRQAELALRAFSGPEIGLLLLPAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCCCEEEECHHH
IVCQVVETFSGVALRLRGAALGAMVVLSVGGATIWVHDLFADGLAVQSVVRPLIEQATIA
HHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VPMLVLLAAWGATVLGGRAAFRVPMLWACAFAVLLVAGPVLALLGGPAAGHAVALPAALF
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ATFAGFYYWIGKMTGRACPERAGRLHVALAVGGSILLLAPHQPAFVSTGVVLLGLSMLAF
HHHHHHHHHHHHHHCCCCHHHCCCEEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHH
VAAIALTLAGRTRPLAANYWGPGARTLEWTVPSPAPRDSFAGILAHGARA
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2155830; 7651515; 9380672; 10338009; 8794157 [H]