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The map label for this gene is 162147853

Identifier: 162147853

GI number: 162147853

Start: 2114000

End: 2114668

Strand: Reverse

Name: 162147853

Synonym: GDI_2069

Alternate gene names: NA

Gene position: 2114668-2114000 (Counterclockwise)

Preceding gene: 162147854

Following gene: 162147851

Centisome position: 53.62

GC content: 75.04

Gene sequence:

>669_bases
ATGGCGGCGGTCGAACGGCTGGGCTGGCAGGCCCATGCCATGCCCGCGCTGCGGATCGAACCGATCATGGATGCCGTGTT
GCCGCTGGCCCGCACCCAGGCCGTCCTGCTGACCAGCGGGCAGGCCATCGCGGCGCTGGCGGGCCGCGTACGGCCCGACA
TGCCGATTCTGGCGGTCGGCGCGGTCACGGCCCGACGGATGCGCGATGCGGGATTCACCGACGTCACGGTGGCGGCGGGA
ACGGCGGCCGACCTGGCGGACCTCGCCCGCGACCGGCTGGACCCGGGGGCGGGGTCCCTGCTGGTGCCGACGGCGCCCAC
CTATGGACAGGATCTGGCCGTGGCGCTGCGGCGGGCCGGGTTCCGCGTCAGCCGGCGCTGCGTCTATCGGGTGCGGCCCG
CGGGGGCGCCCGACGCGGCGGTTCGCACGGCCCTGGCCGGGGGCGTCATCGACGCGGCCCTGTTCTATTCGGCCGAGACG
GCACGCCAGTTCCTGCGTCACCTGCCGGCGGGCGGGCACGCCGCCCTGCGGAACATCCGGGCGATCGCGATTTCAAAGTC
AACCGAGGCGGCGCTGTCCACGGCGACCTGGCGTGCGATCCAGGTCGCGGCACGACCCGACCAGGCGGCGATCCTGGACC
GGCTGGGGCGGCGACCGGCCGGGGAATGA

Upstream 100 bases:

>100_bases
AGCCTTCGGATGGACAGCCCATCGGACGTCTTTGCCGCCTGACGCACCGCCCCGCACCGGCGTTCTGGTCACACGGCCGG
AACCCGGGCTGGCCGACACC

Downstream 100 bases:

>100_bases
AAGCCGCAAAATGAAAAAGGCCCGCGCGAGGCGGGCCTTCGATGGGGGGCCTCAGGCGGCCCGCCCGGATATCCCGATCA
GGCGTTGCCGGCCGTCTGGG

Product: uroporphyrinogen III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MAAVERLGWQAHAMPALRIEPIMDAVLPLARTQAVLLTSGQAIAALAGRVRPDMPILAVGAVTARRMRDAGFTDVTVAAG
TAADLADLARDRLDPGAGSLLVPTAPTYGQDLAVALRRAGFRVSRRCVYRVRPAGAPDAAVRTALAGGVIDAALFYSAET
ARQFLRHLPAGGHAALRNIRAIAISKSTEAALSTATWRAIQVAARPDQAAILDRLGRRPAGE

Sequences:

>Translated_222_residues
MAAVERLGWQAHAMPALRIEPIMDAVLPLARTQAVLLTSGQAIAALAGRVRPDMPILAVGAVTARRMRDAGFTDVTVAAG
TAADLADLARDRLDPGAGSLLVPTAPTYGQDLAVALRRAGFRVSRRCVYRVRPAGAPDAAVRTALAGGVIDAALFYSAET
ARQFLRHLPAGGHAALRNIRAIAISKSTEAALSTATWRAIQVAARPDQAAILDRLGRRPAGE
>Mature_221_residues
AAVERLGWQAHAMPALRIEPIMDAVLPLARTQAVLLTSGQAIAALAGRVRPDMPILAVGAVTARRMRDAGFTDVTVAAGT
AADLADLARDRLDPGAGSLLVPTAPTYGQDLAVALRRAGFRVSRRCVYRVRPAGAPDAAVRTALAGGVIDAALFYSAETA
RQFLRHLPAGGHAALRNIRAIAISKSTEAALSTATWRAIQVAARPDQAAILDRLGRRPAGE

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23239; Mature: 23108

Theoretical pI: Translated: 11.76; Mature: 11.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVERLGWQAHAMPALRIEPIMDAVLPLARTQAVLLTSGQAIAALAGRVRPDMPILAVG
CCCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCCEEEHH
AVTARRMRDAGFTDVTVAAGTAADLADLARDRLDPGAGSLLVPTAPTYGQDLAVALRRAG
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHC
FRVSRRCVYRVRPAGAPDAAVRTALAGGVIDAALFYSAETARQFLRHLPAGGHAALRNIR
HHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIAISKSTEAALSTATWRAIQVAARPDQAAILDRLGRRPAGE
HEEECCCHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AAVERLGWQAHAMPALRIEPIMDAVLPLARTQAVLLTSGQAIAALAGRVRPDMPILAVG
CCHHHHCCHHHCCCCHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCCEEEHH
AVTARRMRDAGFTDVTVAAGTAADLADLARDRLDPGAGSLLVPTAPTYGQDLAVALRRAG
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHC
FRVSRRCVYRVRPAGAPDAAVRTALAGGVIDAALFYSAETARQFLRHLPAGGHAALRNIR
HHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AIAISKSTEAALSTATWRAIQVAARPDQAAILDRLGRRPAGE
HEEECCCHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA