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The map label for this gene is pucG [H]

Identifier: 162147778

GI number: 162147778

Start: 2028176

End: 2029450

Strand: Reverse

Name: pucG [H]

Synonym: GDI_1994

Alternate gene names: 162147778

Gene position: 2029450-2028176 (Counterclockwise)

Preceding gene: 162147779

Following gene: 162147777

Centisome position: 51.45

GC content: 69.96

Gene sequence:

>1275_bases
GTGAAGACAATGGAGGATACGGGGACGATGTTCGGGCAGATCGATCCGCCGCAGCGGCTGCTGATGGGGCCGGGGCCGGT
GAATGTGCATCCGCGCGTGCTGCGCGCGATGACGGCGGACATGCTGGGCCAGTTCGACCCGGAGATGACGGGGTACATGA
ACCAGACGATGGCGCTGTACCGCCAGGTGTTCATGACCGAAAACCGCTGGACCTTCCTGGTCGACGGCACGGCGCGGGCG
GGGATCGAGGCCGCCCTGGTCTCGCTGGTCGAGCCGGGGGCGCGGCTGCTGATCCTGCGGGCGGGCCGGTTCGGGCTGCT
GCTGTCGGAAATCGCGCAGCGCATCGGCGCCGAGATCCGCACCATCGACATCCCGTGGGGCGAGGTCGCGCCCCCGGAGC
AGATCGAGGCCGCGATCATCGAACACCGGCCGCAGGTCTTCGCCACCATCCACGGCGATACCTCGACCACCATGGCCCAG
CCGCTGGACGGCGTGGGGGCGATCTGCCGGCGGCACGGCGTGCTGTCCTATGTCGATGCCACGGCGACGCTGGGCGGTAT
GGCGGTGGCGACCGACGCCTGGGGCGTGGATGTGGTGACGGGCGGATTGCAGAAATGCATGGGCGGTCCGCCGGGCTCGG
CCCCCATCACCATCTCGGACCGGGCGGCGGCGCATATCATGGCCCGCCGGCATGTCGAGGCCGGGATCAGGGGCGCCGAT
GCCCAGGATGGCAGCCGGACGCGGATCGGATCGAACTATTTCGACCTGGCCATGATCATGGAATACTGGTCCGAGAAGCG
GCTGAACCACCATACCGAAGCGACCTCCATGCTCTATGCGGCGCGCGAGGCGGCGCGGATCATGGTGGAAGAGGGGCTGG
AGGCGCGCTTCGCCCGGCATCGCGCCGCGAGTGAGGCCATGGCCGCCGGATTGCGGGCGATGGGCCTGACGCTGTACGGC
CAGGATGCGTACCGCATGGCCAACGTCACCGGCGTGTTCATCCCCGACGGCGTGGATGGTGAGCGCGCCCGCACCCGCAT
GCGCGAGGAGTTTGAGATCGAGATCGGCACCGCCTTCGGCCCGCTGGCGGGCCGGATCTGGCGCATCGGCGCCATGGGCT
ACAACGCCATGAAGCACAAGGTGCTGATCACGCTGGGCGCGCTGGAAGCCGTGCTGGCCGCCGAAGGCCACGCCCTGCCG
CGCGGGGCCGGCGTGGATGCCGCCCGCGCGTCCTACGAGGCCATGCCCGGGGCCGCACCCGGGGCCGCGTCATGA

Upstream 100 bases:

>100_bases
CCGTCCGGGTCGAGGATGCCGATCTGGCCCTGCGGGCGATGACGGATTTTATCGAACGGTTCGATGCCCGGGCAGCGGCT
TCGGCACAACAGGGTACGCA

Downstream 100 bases:

>100_bases
CGGACCCGTATCCCCGCGACCTGGTCGGCTATGCCGGCCATCCGCCCGATCCGCGCTGGCCGGGGCAGGCCCGGGTCGCC
GTGCAGTTCGTCATCAATTA

Product: serine-pyruvate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKTMEDTGTMFGQIDPPQRLLMGPGPVNVHPRVLRAMTADMLGQFDPEMTGYMNQTMALYRQVFMTENRWTFLVDGTARA
GIEAALVSLVEPGARLLILRAGRFGLLLSEIAQRIGAEIRTIDIPWGEVAPPEQIEAAIIEHRPQVFATIHGDTSTTMAQ
PLDGVGAICRRHGVLSYVDATATLGGMAVATDAWGVDVVTGGLQKCMGGPPGSAPITISDRAAAHIMARRHVEAGIRGAD
AQDGSRTRIGSNYFDLAMIMEYWSEKRLNHHTEATSMLYAAREAARIMVEEGLEARFARHRAASEAMAAGLRAMGLTLYG
QDAYRMANVTGVFIPDGVDGERARTRMREEFEIEIGTAFGPLAGRIWRIGAMGYNAMKHKVLITLGALEAVLAAEGHALP
RGAGVDAARASYEAMPGAAPGAAS

Sequences:

>Translated_424_residues
MKTMEDTGTMFGQIDPPQRLLMGPGPVNVHPRVLRAMTADMLGQFDPEMTGYMNQTMALYRQVFMTENRWTFLVDGTARA
GIEAALVSLVEPGARLLILRAGRFGLLLSEIAQRIGAEIRTIDIPWGEVAPPEQIEAAIIEHRPQVFATIHGDTSTTMAQ
PLDGVGAICRRHGVLSYVDATATLGGMAVATDAWGVDVVTGGLQKCMGGPPGSAPITISDRAAAHIMARRHVEAGIRGAD
AQDGSRTRIGSNYFDLAMIMEYWSEKRLNHHTEATSMLYAAREAARIMVEEGLEARFARHRAASEAMAAGLRAMGLTLYG
QDAYRMANVTGVFIPDGVDGERARTRMREEFEIEIGTAFGPLAGRIWRIGAMGYNAMKHKVLITLGALEAVLAAEGHALP
RGAGVDAARASYEAMPGAAPGAAS
>Mature_424_residues
MKTMEDTGTMFGQIDPPQRLLMGPGPVNVHPRVLRAMTADMLGQFDPEMTGYMNQTMALYRQVFMTENRWTFLVDGTARA
GIEAALVSLVEPGARLLILRAGRFGLLLSEIAQRIGAEIRTIDIPWGEVAPPEQIEAAIIEHRPQVFATIHGDTSTTMAQ
PLDGVGAICRRHGVLSYVDATATLGGMAVATDAWGVDVVTGGLQKCMGGPPGSAPITISDRAAAHIMARRHVEAGIRGAD
AQDGSRTRIGSNYFDLAMIMEYWSEKRLNHHTEATSMLYAAREAARIMVEEGLEARFARHRAASEAMAAGLRAMGLTLYG
QDAYRMANVTGVFIPDGVDGERARTRMREEFEIEIGTAFGPLAGRIWRIGAMGYNAMKHKVLITLGALEAVLAAEGHALP
RGAGVDAARASYEAMPGAAPGAAS

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=380, Percent_Identity=33.1578947368421, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17536281, Length=369, Percent_Identity=35.230352303523, Blast_Score=238, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6321079, Length=333, Percent_Identity=22.5225225225225, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17530823, Length=385, Percent_Identity=33.2467532467532, Blast_Score=218, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 45532; Mature: 45532

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMEDTGTMFGQIDPPQRLLMGPGPVNVHPRVLRAMTADMLGQFDPEMTGYMNQTMALY
CCCCCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RQVFMTENRWTFLVDGTARAGIEAALVSLVEPGARLLILRAGRFGLLLSEIAQRIGAEIR
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCEE
TIDIPWGEVAPPEQIEAAIIEHRPQVFATIHGDTSTTMAQPLDGVGAICRRHGVLSYVDA
EEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHCCCHHHHHHHHHCCCHHHHHH
TATLGGMAVATDAWGVDVVTGGLQKCMGGPPGSAPITISDRAAAHIMARRHVEAGIRGAD
HHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCC
AQDGSRTRIGSNYFDLAMIMEYWSEKRLNHHTEATSMLYAAREAARIMVEEGLEARFARH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASEAMAAGLRAMGLTLYGQDAYRMANVTGVFIPDGVDGERARTRMREEFEIEIGTAFG
HHHHHHHHHHHHHHCEEEECCCHHEEECEEEEEECCCCCCHHHHHHHHHHEEEEECCCCC
PLAGRIWRIGAMGYNAMKHKVLITLGALEAVLAAEGHALPRGAGVDAARASYEAMPGAAP
CHHHHHEEEECCCCHHHHHEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCC
GAAS
CCCC
>Mature Secondary Structure
MKTMEDTGTMFGQIDPPQRLLMGPGPVNVHPRVLRAMTADMLGQFDPEMTGYMNQTMALY
CCCCCCCCCCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RQVFMTENRWTFLVDGTARAGIEAALVSLVEPGARLLILRAGRFGLLLSEIAQRIGAEIR
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCEE
TIDIPWGEVAPPEQIEAAIIEHRPQVFATIHGDTSTTMAQPLDGVGAICRRHGVLSYVDA
EEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHCCCHHHHHHHHHCCCHHHHHH
TATLGGMAVATDAWGVDVVTGGLQKCMGGPPGSAPITISDRAAAHIMARRHVEAGIRGAD
HHHHCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCC
AQDGSRTRIGSNYFDLAMIMEYWSEKRLNHHTEATSMLYAAREAARIMVEEGLEARFARH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASEAMAAGLRAMGLTLYGQDAYRMANVTGVFIPDGVDGERARTRMREEFEIEIGTAFG
HHHHHHHHHHHHHHCEEEECCCHHEEECEEEEEECCCCCCHHHHHHHHHHEEEEECCCCC
PLAGRIWRIGAMGYNAMKHKVLITLGALEAVLAAEGHALPRGAGVDAARASYEAMPGAAP
CHHHHHEEEECCCCHHHHHEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCC
GAAS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]