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The map label for this gene is mcpA [H]

Identifier: 162147731

GI number: 162147731

Start: 1981230

End: 1982867

Strand: Reverse

Name: mcpA [H]

Synonym: GDI_1947

Alternate gene names: 162147731

Gene position: 1982867-1981230 (Counterclockwise)

Preceding gene: 162147732

Following gene: 162147730

Centisome position: 50.27

GC content: 64.77

Gene sequence:

>1638_bases
ATGTTGGAACCGGACACGCTTGCCGACCGCCTTCAGTTTGTCAAGCTTGACTCGAAGACCAGACAAAATCTGCGCGGTAT
CAAATCGATCATCATGCGTGCGTTGCCGGGCGCCCTGGATAAATTTTACGATCAGGTCCGGTCTTTTCCCAAGACACGTC
ATTTTTTTTCCGGCCAGGCGCATATCGATGCTGCCAAGAGCCGGCAGATTGCGCATTGGGGAACGATTTCCGACGCGCGG
TTCGACCAATCCTATATGGAGGCGGCCACCAGGATCGGCGAGGTTCACGCACGGGTCGGCCTGGAGCCGCGCTGGCATAT
CGGCGGCTATGCGCTGCTGATCGAATCCATGTTGGGTGCCCTGCTGGAAGCACGCTGGCCCAGGGCCGGCCTTGCGGCCA
GAATCGGCCTGGGCGGAGGTGCCGACGTCAGGCAGGTGGCGGAGGAAGCCGGCGCGCTGGTGAAGGCCGCCCTGATCGAC
ATGGATTATGCCATTTCCGCTTACCTCGAAGCATCGGAAACCGCCCGGCAGAAGGTCGAGGCCGACGTCCTGGCCAGGGA
GCGCGGAACGGTGGTGGACCGGGTGGGCGCGGGCATGGCGGCCCTGGCCACCGGTGACCTGACATTCCGCATGTCCAGCG
ACGTCCCCGAGGAGTACCGCAAGCTTCAGGAGGATTTCAACGGCGCGATCGAAAGCCTGCAGACCACGATGCAGGCGATC
GACACCAACGCGCAGGCCGTTCGCACCGGATCGGACGAAATCCGGCAGGCGTCGGACGACCTGGCACGACGGACCGCACA
GCAGGCGGCCAGCCTCGAACAGGCCGCCGCCACGCTCGACGGCATCACCACCACGGTCCGCAGGTCGGCCGAGGATGCGG
GCCAGGCGCGCCATATGGCGACGGTCGCGAAAACCGACGCCGAGCGTTCCGGGGACGTCGTGCGCCAGACCGTGACGACC
ATGAGCGGGATCGAGGCATCGTCCAGGCAGATCGGCAGCATCATCGGCATCATCGACGAGATCGCTTTCCTGACCAATCT
GTTGGCGGTCAATGCCGGGGTCGAGGCGGCCCGGGCCGGAGACGCCGGCCGCGGCTTCGCCGTGGTGGCGACGGAGGTGC
GTGCCCTGGCGCAACGTTCCGCCGAAGCGGCAAAGGAAATCAAGGAGTTGATTTCGGCGTCCGGCCGGCAGGTGACGACC
GGCGTGAAGTTGGTTGGCGAGACCGGCAAGGCGCTGGACCGTATCGTCGAACAGGTTAGCCGCCTGAACGTCCTGGTGAC
GGATATAGCGATCTCCTCCGCGAACCAGGCGACAGGGTTGAACGAGGTCAATGACGCCGTGAACCAGATGGACCAGGTGA
CGCAACAGAACGCCGCAATGGTGGAGCAATCCGCCGCTGCCAGCCGCAGCATGGCCAATGAGGCGGAAGATCTGGCGCGT
CTGGTCGAGCAGTTCCAGACCGGTCACAGCCAGGCGTTTCAGACCGCCTCGCGGACCGGGCCCGCACCTGCGGCGAGCCT
CTGGCAGGACGAGGAGTCATCGGCCTACATGCCGGCTGCGGCTTCCCGTTCCGCGGCGGGGGGCAATGTCCTGTCCTTTC
CTGCTGCAAAAGGCGCGGATGGCTGGGACGAATTCTGA

Upstream 100 bases:

>100_bases
AATAGACAAATTTGTATTGTTTACAAATAAAACGTGATGGTATGATTTAAGGAACTTACCACAAGCGATTGAATTAAGTC
GTATTTTCTGGATCATGTAA

Downstream 100 bases:

>100_bases
AAGCGGATTACATTCATGCCCTTCCATGAGATATCTAAATACGTGGAATTAAATATCCTGATATTATTATGATTGATGGG
GCTGTATTTTTTGGAATAAA

Product: chemoreceptor mcpA (methyl-accepting chemotaxis protein)

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MLEPDTLADRLQFVKLDSKTRQNLRGIKSIIMRALPGALDKFYDQVRSFPKTRHFFSGQAHIDAAKSRQIAHWGTISDAR
FDQSYMEAATRIGEVHARVGLEPRWHIGGYALLIESMLGALLEARWPRAGLAARIGLGGGADVRQVAEEAGALVKAALID
MDYAISAYLEASETARQKVEADVLARERGTVVDRVGAGMAALATGDLTFRMSSDVPEEYRKLQEDFNGAIESLQTTMQAI
DTNAQAVRTGSDEIRQASDDLARRTAQQAASLEQAAATLDGITTTVRRSAEDAGQARHMATVAKTDAERSGDVVRQTVTT
MSGIEASSRQIGSIIGIIDEIAFLTNLLAVNAGVEAARAGDAGRGFAVVATEVRALAQRSAEAAKEIKELISASGRQVTT
GVKLVGETGKALDRIVEQVSRLNVLVTDIAISSANQATGLNEVNDAVNQMDQVTQQNAAMVEQSAAASRSMANEAEDLAR
LVEQFQTGHSQAFQTASRTGPAPAASLWQDEESSAYMPAAASRSAAGGNVLSFPAAKGADGWDEF

Sequences:

>Translated_545_residues
MLEPDTLADRLQFVKLDSKTRQNLRGIKSIIMRALPGALDKFYDQVRSFPKTRHFFSGQAHIDAAKSRQIAHWGTISDAR
FDQSYMEAATRIGEVHARVGLEPRWHIGGYALLIESMLGALLEARWPRAGLAARIGLGGGADVRQVAEEAGALVKAALID
MDYAISAYLEASETARQKVEADVLARERGTVVDRVGAGMAALATGDLTFRMSSDVPEEYRKLQEDFNGAIESLQTTMQAI
DTNAQAVRTGSDEIRQASDDLARRTAQQAASLEQAAATLDGITTTVRRSAEDAGQARHMATVAKTDAERSGDVVRQTVTT
MSGIEASSRQIGSIIGIIDEIAFLTNLLAVNAGVEAARAGDAGRGFAVVATEVRALAQRSAEAAKEIKELISASGRQVTT
GVKLVGETGKALDRIVEQVSRLNVLVTDIAISSANQATGLNEVNDAVNQMDQVTQQNAAMVEQSAAASRSMANEAEDLAR
LVEQFQTGHSQAFQTASRTGPAPAASLWQDEESSAYMPAAASRSAAGGNVLSFPAAKGADGWDEF
>Mature_545_residues
MLEPDTLADRLQFVKLDSKTRQNLRGIKSIIMRALPGALDKFYDQVRSFPKTRHFFSGQAHIDAAKSRQIAHWGTISDAR
FDQSYMEAATRIGEVHARVGLEPRWHIGGYALLIESMLGALLEARWPRAGLAARIGLGGGADVRQVAEEAGALVKAALID
MDYAISAYLEASETARQKVEADVLARERGTVVDRVGAGMAALATGDLTFRMSSDVPEEYRKLQEDFNGAIESLQTTMQAI
DTNAQAVRTGSDEIRQASDDLARRTAQQAASLEQAAATLDGITTTVRRSAEDAGQARHMATVAKTDAERSGDVVRQTVTT
MSGIEASSRQIGSIIGIIDEIAFLTNLLAVNAGVEAARAGDAGRGFAVVATEVRALAQRSAEAAKEIKELISASGRQVTT
GVKLVGETGKALDRIVEQVSRLNVLVTDIAISSANQATGLNEVNDAVNQMDQVTQQNAAMVEQSAAASRSMANEAEDLAR
LVEQFQTGHSQAFQTASRTGPAPAASLWQDEESSAYMPAAASRSAAGGNVLSFPAAKGADGWDEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=261, Percent_Identity=48.6590038314176, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI2367378, Length=266, Percent_Identity=45.4887218045113, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787690, Length=307, Percent_Identity=40.0651465798046, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788195, Length=272, Percent_Identity=43.3823529411765, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789453, Length=239, Percent_Identity=38.0753138075314, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58079; Mature: 58079

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEPDTLADRLQFVKLDSKTRQNLRGIKSIIMRALPGALDKFYDQVRSFPKTRHFFSGQA
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCC
HIDAAKSRQIAHWGTISDARFDQSYMEAATRIGEVHARVGLEPRWHIGGYALLIESMLGA
HHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LLEARWPRAGLAARIGLGGGADVRQVAEEAGALVKAALIDMDYAISAYLEASETARQKVE
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVLARERGTVVDRVGAGMAALATGDLTFRMSSDVPEEYRKLQEDFNGAIESLQTTMQAI
HHHHHHHCCCHHHHHCCCHHHEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTNAQAVRTGSDEIRQASDDLARRTAQQAASLEQAAATLDGITTTVRRSAEDAGQARHMA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAKTDAERSGDVVRQTVTTMSGIEASSRQIGSIIGIIDEIAFLTNLLAVNAGVEAARAG
HHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
DAGRGFAVVATEVRALAQRSAEAAKEIKELISASGRQVTTGVKLVGETGKALDRIVEQVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHHHHHHHH
RLNVLVTDIAISSANQATGLNEVNDAVNQMDQVTQQNAAMVEQSAAASRSMANEAEDLAR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEQFQTGHSQAFQTASRTGPAPAASLWQDEESSAYMPAAASRSAAGGNVLSFPAAKGAD
HHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GWDEF
CCCCC
>Mature Secondary Structure
MLEPDTLADRLQFVKLDSKTRQNLRGIKSIIMRALPGALDKFYDQVRSFPKTRHFFSGQA
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCC
HIDAAKSRQIAHWGTISDARFDQSYMEAATRIGEVHARVGLEPRWHIGGYALLIESMLGA
HHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LLEARWPRAGLAARIGLGGGADVRQVAEEAGALVKAALIDMDYAISAYLEASETARQKVE
HHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADVLARERGTVVDRVGAGMAALATGDLTFRMSSDVPEEYRKLQEDFNGAIESLQTTMQAI
HHHHHHHCCCHHHHHCCCHHHEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTNAQAVRTGSDEIRQASDDLARRTAQQAASLEQAAATLDGITTTVRRSAEDAGQARHMA
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAKTDAERSGDVVRQTVTTMSGIEASSRQIGSIIGIIDEIAFLTNLLAVNAGVEAARAG
HHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
DAGRGFAVVATEVRALAQRSAEAAKEIKELISASGRQVTTGVKLVGETGKALDRIVEQVS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCHHHHHHHHHHHH
RLNVLVTDIAISSANQATGLNEVNDAVNQMDQVTQQNAAMVEQSAAASRSMANEAEDLAR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEQFQTGHSQAFQTASRTGPAPAASLWQDEESSAYMPAAASRSAAGGNVLSFPAAKGAD
HHHHHHCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
GWDEF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]