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The map label for this gene is grxC [H]

Identifier: 162147688

GI number: 162147688

Start: 1940034

End: 1940324

Strand: Direct

Name: grxC [H]

Synonym: GDI_1904

Alternate gene names: 162147688

Gene position: 1940034-1940324 (Clockwise)

Preceding gene: 162147687

Following gene: 162147689

Centisome position: 49.19

GC content: 65.64

Gene sequence:

>291_bases
TTGATAACAGGCCGCTATTCGAGGATCAGGATGCCCAGGATCGAGATCTATACCCAGCCGGGATGCCCCTATTGCGTCCG
CGCACTCCGCCTGCTGGAGCAGAAGGGCACGGCTTTTACCGAAATCCGCGCCCTGCACGGCACGGCCGAACGCGCGGAGG
CGCGGGAGCGTTCCGGTGGCCGGACAACCGTGCCGCAGATCTTCATCGACGGGCGGCATATCGGCGGCTGTGACGACATC
ATGGCGCTGGACCGTGCCGGCAAGCTGGACCCGCTGCTGCATGCGGCGTGA

Upstream 100 bases:

>100_bases
TGCTGGTGGCGGCCCGCGCGCCCGATCCCGGCCGCGATCCGTCCCAGGATACGGGGCAGCACCCGTAACGGTATGTTGCC
CCGGCATAAATGCGCTATGC

Downstream 100 bases:

>100_bases
TCGCCAGCATCCGGTCCAGACCAGGGGGCGCCGGTGATCCGCTATCTGCTGCGTTGCGATGCGGGGCATGAGTTCGATGG
CTGGTTCCCCGGCAGCGCCG

Product: glutaredoxin-3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MITGRYSRIRMPRIEIYTQPGCPYCVRALRLLEQKGTAFTEIRALHGTAERAEARERSGGRTTVPQIFIDGRHIGGCDDI
MALDRAGKLDPLLHAA

Sequences:

>Translated_96_residues
MITGRYSRIRMPRIEIYTQPGCPYCVRALRLLEQKGTAFTEIRALHGTAERAEARERSGGRTTVPQIFIDGRHIGGCDDI
MALDRAGKLDPLLHAA
>Mature_96_residues
MITGRYSRIRMPRIEIYTQPGCPYCVRALRLLEQKGTAFTEIRALHGTAERAEARERSGGRTTVPQIFIDGRHIGGCDDI
MALDRAGKLDPLLHAA

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=59.0361445783133, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 10709; Mature: 10709

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITGRYSRIRMPRIEIYTQPGCPYCVRALRLLEQKGTAFTEIRALHGTAERAEARERSGG
CCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCC
RTTVPQIFIDGRHIGGCDDIMALDRAGKLDPLLHAA
CCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MITGRYSRIRMPRIEIYTQPGCPYCVRALRLLEQKGTAFTEIRALHGTAERAEARERSGG
CCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCC
RTTVPQIFIDGRHIGGCDDIMALDRAGKLDPLLHAA
CCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]