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The map label for this gene is cobS [H]

Identifier: 162147677

GI number: 162147677

Start: 1930707

End: 1931708

Strand: Reverse

Name: cobS [H]

Synonym: GDI_1893

Alternate gene names: 162147677

Gene position: 1931708-1930707 (Counterclockwise)

Preceding gene: 162147678

Following gene: 162147676

Centisome position: 48.98

GC content: 64.87

Gene sequence:

>1002_bases
ATGAATGACCTCGCCACCCTGACCGCCGGATCGACTGCCGAAAACGGGGATGACCTGCCGCCGATCTCGGTCCTGTCCGC
CCCCGACCGCACGGTCTCCGCCCGCGATGTCTTCGGCATCGACAGCGATCTGCAGGTGCCCGCCTTCTCGGTGCGGACCG
ATCACGTACCGGATGCCGATCCGACCTATCGCTTCGATCACGACACCACGCTGGCCATCCTGGCCGGCTTCGCCTTCAAC
CGGCGCGTGATGATCCAGGGCTATCACGGCACCGGCAAGTCGTCGCATGTCGAACAGGTGGCGTCGCGGCTGAACTGGCC
GTGCGTGCGCATCAACCTGGACAGCCATATCTCGCGCATCGACCTGATCGGCAAGGATGCCATCGTGCTGCGCGACGGCA
AGCAGGTGACGGAATTCCGCGAAGGGCTGCTGCCCTGGGGGCTGCAGCACCCCTGCGCCCTGGTGTTCGACGAATATGAT
GCCGGGCGGCCGGACGTCATGTTCGTCATCCAGCGCGTGCTGGAGGTCGAGGGCCATCTGACGCTGCTGGACCAGAACCG
CGTGATCCGCCCGCACCCGTTCTTCCGCCTGTTCGCCACGGCGAACACGGTGGGCCTGGGCGACACCACCGGCCTGTATC
ACGGCACGCAGCAGATCAATCAGGGCCAGATGGACCGCTGGAACGTGGTCACCACCCTGAACTACCTGCCCCATGCCGAG
GAAACGGCCATCGTCGTGGCCAAGATGGCCGTCGATCCCAGCGATGCCCCGGCCCGCAAGCGGATCGAAAGCATGGTCGC
CCTGGCCGACCTGACGCGTTCGGGCTTCATCGCCGGCGACATCTCGACGGTCATGTCGCCGCGCACGGTCATCAGCTGGG
CCGAGAATGCCAGGATCTTCAAGGATCTGGAATTCGCCTTCCGCGTGTCCTTCCTGAACAAGTGCGACGAGGCCGAGCGT
CGACGGTGGCGGAATATTACCAGCGCTGCTTCAACGTTCTGA

Upstream 100 bases:

>100_bases
CCGAACCCGGACATCGAATTCCGGGACGCCGAAGACCATATGACACGGACCGTCGCCACGGCGCGCGGCGGGACCAACCA
GCCGTGACGGATGCACCCCG

Downstream 100 bases:

>100_bases
CCCCACCGGCACGGCGCCGCGCGCGCGCTGATCGGCCCGGGAAGCCATGCGCGACCGCAAGGACACCACCCAGTCCGCAC
GATTGGCCGCCGCCGAGCGG

Product: aerobic cobaltochelatase cobS

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNDLATLTAGSTAENGDDLPPISVLSAPDRTVSARDVFGIDSDLQVPAFSVRTDHVPDADPTYRFDHDTTLAILAGFAFN
RRVMIQGYHGTGKSSHVEQVASRLNWPCVRINLDSHISRIDLIGKDAIVLRDGKQVTEFREGLLPWGLQHPCALVFDEYD
AGRPDVMFVIQRVLEVEGHLTLLDQNRVIRPHPFFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNVVTTLNYLPHAE
ETAIVVAKMAVDPSDAPARKRIESMVALADLTRSGFIAGDISTVMSPRTVISWAENARIFKDLEFAFRVSFLNKCDEAER
RRWRNITSAASTF

Sequences:

>Translated_333_residues
MNDLATLTAGSTAENGDDLPPISVLSAPDRTVSARDVFGIDSDLQVPAFSVRTDHVPDADPTYRFDHDTTLAILAGFAFN
RRVMIQGYHGTGKSSHVEQVASRLNWPCVRINLDSHISRIDLIGKDAIVLRDGKQVTEFREGLLPWGLQHPCALVFDEYD
AGRPDVMFVIQRVLEVEGHLTLLDQNRVIRPHPFFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNVVTTLNYLPHAE
ETAIVVAKMAVDPSDAPARKRIESMVALADLTRSGFIAGDISTVMSPRTVISWAENARIFKDLEFAFRVSFLNKCDEAER
RRWRNITSAASTF
>Mature_333_residues
MNDLATLTAGSTAENGDDLPPISVLSAPDRTVSARDVFGIDSDLQVPAFSVRTDHVPDADPTYRFDHDTTLAILAGFAFN
RRVMIQGYHGTGKSSHVEQVASRLNWPCVRINLDSHISRIDLIGKDAIVLRDGKQVTEFREGLLPWGLQHPCALVFDEYD
AGRPDVMFVIQRVLEVEGHLTLLDQNRVIRPHPFFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNVVTTLNYLPHAE
ETAIVVAKMAVDPSDAPARKRIESMVALADLTRSGFIAGDISTVMSPRTVISWAENARIFKDLEFAFRVSFLNKCDEAER
RRWRNITSAASTF

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161076562, Length=186, Percent_Identity=29.5698924731183, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161076560, Length=186, Percent_Identity=29.5698924731183, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 37064; Mature: 37064

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLATLTAGSTAENGDDLPPISVLSAPDRTVSARDVFGIDSDLQVPAFSVRTDHVPDAD
CCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHEECCCCCCCCCEEEEECCCCCCCC
PTYRFDHDTTLAILAGFAFNRRVMIQGYHGTGKSSHVEQVASRLNWPCVRINLDSHISRI
CCEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEHHHCCCEE
DLIGKDAIVLRDGKQVTEFREGLLPWGLQHPCALVFDEYDAGRPDVMFVIQRVLEVEGHL
EECCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCE
TLLDQNRVIRPHPFFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNVVTTLNYLPHAE
EEEECCCEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCC
ETAIVVAKMAVDPSDAPARKRIESMVALADLTRSGFIAGDISTVMSPRTVISWAENARIF
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEECHHHHCCCHHEEEHHHCCHHH
KDLEFAFRVSFLNKCDEAERRRWRNITSAASTF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDLATLTAGSTAENGDDLPPISVLSAPDRTVSARDVFGIDSDLQVPAFSVRTDHVPDAD
CCCCEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHEECCCCCCCCCEEEEECCCCCCCC
PTYRFDHDTTLAILAGFAFNRRVMIQGYHGTGKSSHVEQVASRLNWPCVRINLDSHISRI
CCEEECCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEHHHCCCEE
DLIGKDAIVLRDGKQVTEFREGLLPWGLQHPCALVFDEYDAGRPDVMFVIQRVLEVEGHL
EECCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCE
TLLDQNRVIRPHPFFRLFATANTVGLGDTTGLYHGTQQINQGQMDRWNVVTTLNYLPHAE
EEEECCCEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCC
ETAIVVAKMAVDPSDAPARKRIESMVALADLTRSGFIAGDISTVMSPRTVISWAENARIF
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEECHHHHCCCHHEEEHHHCCHHH
KDLEFAFRVSFLNKCDEAERRRWRNITSAASTF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]