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The map label for this gene is recG [H]

Identifier: 162147668

GI number: 162147668

Start: 1917388

End: 1919565

Strand: Reverse

Name: recG [H]

Synonym: GDI_1884

Alternate gene names: 162147668

Gene position: 1919565-1917388 (Counterclockwise)

Preceding gene: 162147672

Following gene: 162147666

Centisome position: 48.67

GC content: 71.26

Gene sequence:

>2178_bases
GTGAAAGCGGTCGAACACCACGTGTCTGGCATCATCCTTCAGGACGAAAGGGACGACAATCTCGGTCCGCTGCTGGCCCC
GCTGGGCAGCCTGCCCGGGGTCGGCCCTGCCCTGGCCAAGCTGCTGGCGCGGGCCGTGCGGGGCCAGCGGGTCATCGACC
TGCTGTTCCATCTGCCGGAATCGGTGGTCGATCGCGGGTTATCGCCCCAGCTGTCGCGACGCCCGGAATCGGTGGTCGAT
CACCGCTATCGCCCCAGCCTGCGCAACGCCGTCCCCGGGCGGGGAACCACGATGCAGGTCCGGGTGCGGCGGTTCGACGC
GCCCGCCCGGGGAACGCGCGTGTTCTTTTCCCCGTTGGAGGCCCGGCGCACCGGGGTGGGAGAACTGGTGTTCTTATCCC
CCACGCAGGCCCGGCAGATGCGGGTGGGAGCGACCGTCCCGGTATCGGGCACGCTGGATGCGTTCGGCGACCGGCTGCAG
ATGGCCCACCCCGACCATATCGTGCCGGGCGGCGACATCGACCGCATTCCGGCGCTGGAGCCGGTCTGGCCGCTGACGGC
CGGCCTTTTTCCCCGCCACGTGCGCGCGGCGCTGCACCAGGCGTTCCTTCGCTTTCCCCCGTTGCCGGAATGGCTGGATT
CCGTGCTGGTGGCCCGCCGACACTGGCCGGATTTCGAGACCGCGCTGCGTCAACTGCACTGCCCCGAGGCCTTCCCCGAC
CTGCTGCGCGGCGATGCCTGGCAGGCCGCCGGCGAGCGCGCGCGCCAGCGGCTGGCCTGCGACGAACTGCTGGCCGAACA
GGTCGCGATGTCCGAGGCACGGCGCCGCAACCGCAACCGCCCCGGCCGGTCCATCGTCGGCACGGGCACCCTGCGCGCCG
AGGCGCTGGCCCGGTTCGGCTATACCCCGACCGGGGCCCAGCACCGCGCGGTGCGCGAAATCGATTCGGACCTCGCCGCG
TCATATCCGATGATGCGCCTGCTGCAGGGCGATGTCGGGGCGGGCAAGACGCTGGTGGCGATGCTGGCCATGCTGGCGGC
GGCCGAGGCCGGACACCAGGCGGTGCTGATGGCCCCCACGGAAATCCTGGCCCGCCAGCACCTGGCCACGTTCCAGAAGC
TGGCGCCGGTGCCGGTGGCGTTCCTCAGCGGCAGCGTCAAGGGACGCGCGCGCAGGACCGTGCTGGAAGACATCGCATCC
GGCCGCGCGCCGCTGGTCGTGGGCACGCACGCGCTGTTCCAGGACAAGGTCGTGTTCGACGATTTGGCCCTGGCGGTGAT
CGACGAACAGCACCGGTTCGGGGTCGAGCAGCGCCTGCTGCTGGGTGAGAAGGGCGACCGGGCCGATATCCTGGTCATGA
CCGCTACCCCCATTCCGCGCACGCTGCTGCTGACCCAGTGGGGCGAGATGCAGGTCAGCCGCCTGAACGAAAAACCGGCC
GGACGCCTGCCCGTACGGACGTCCCTGCACGCCATGGCGTCATTGGGCGATGTGCTGGACGGAATCGGGCGCGCGATCGC
ACGCGGCGCCCTGGTCTTCTGGGTCTGCCCGCTGGTCACGGAAAGCGAGGCGATGGACCTGGCGGCGGCGGAGGCGCGCT
TCGCCGCACTGACCGAGCGCTTCGGGCCGATCGTGGGCCTGGCGCACGGCCAGCAGGACATCGCGGTGCGCGAGGCCGCG
ATCGCGGATTTCGCGGCGGGGCGGACGAAGATCCTGGTCGCGACGACGGTGATCGAGGTCGGCGTGGACATCCCCGCCGC
CACCATCATGGTCATCGAACACGCCGAACGGTTCGGCCTGGCGCAACTGCACCAGTTGCGCGGGCGCGTGGGACGCGGCC
GCGACGAATCGTTCTGCCTGCTGCTGCATGACGACGCGCTGGGCAGCACGGCCCGGCGCCGGCTGGCCCTGCTGCGCGAT
ACCGAGGACGGGTTCCTGATCGCGGACGAGGATTTCCGCCTGCGCGGCGGCGGCGACGTCACCGGCCGCCGCCAGTCCGG
ACTGCCGGACCTGCGGCTTGCGACCGGTGCGCGGCTGGACCTGTTGCTGACGATCGCGGCCCAGGACGCGCAGCGGGTCG
CCGAAGGGGGCGCCAGCGAATCGCGCCGCAACGCGATCGCCCAGTTGCTGGAACTGTTCGACCGGCACGATGCCGCCCGA
ATCCTGCGCTCGGGGTAG

Upstream 100 bases:

>100_bases
GTTCCTTCGCGTCGCTGTCCTATAGCCCTCCATCAGGTTCCTGTCAGCCCGCCCATCGACGCAACGACCGAAGGGCCGCC
CCAGGACACGAAATCGGGAA

Downstream 100 bases:

>100_bases
TAGGCTTAGAATTTCCCGGACAGGGCCAGCGATCCGTAATTGAACAGGCCGCTGCGCGCGCCACGGAATTCCTGCGTCTG
CCAGACCTGGCTGTAGGACA

Product: ATP-dependent DNA helicase recG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MKAVEHHVSGIILQDERDDNLGPLLAPLGSLPGVGPALAKLLARAVRGQRVIDLLFHLPESVVDRGLSPQLSRRPESVVD
HRYRPSLRNAVPGRGTTMQVRVRRFDAPARGTRVFFSPLEARRTGVGELVFLSPTQARQMRVGATVPVSGTLDAFGDRLQ
MAHPDHIVPGGDIDRIPALEPVWPLTAGLFPRHVRAALHQAFLRFPPLPEWLDSVLVARRHWPDFETALRQLHCPEAFPD
LLRGDAWQAAGERARQRLACDELLAEQVAMSEARRRNRNRPGRSIVGTGTLRAEALARFGYTPTGAQHRAVREIDSDLAA
SYPMMRLLQGDVGAGKTLVAMLAMLAAAEAGHQAVLMAPTEILARQHLATFQKLAPVPVAFLSGSVKGRARRTVLEDIAS
GRAPLVVGTHALFQDKVVFDDLALAVIDEQHRFGVEQRLLLGEKGDRADILVMTATPIPRTLLLTQWGEMQVSRLNEKPA
GRLPVRTSLHAMASLGDVLDGIGRAIARGALVFWVCPLVTESEAMDLAAAEARFAALTERFGPIVGLAHGQQDIAVREAA
IADFAAGRTKILVATTVIEVGVDIPAATIMVIEHAERFGLAQLHQLRGRVGRGRDESFCLLLHDDALGSTARRRLALLRD
TEDGFLIADEDFRLRGGGDVTGRRQSGLPDLRLATGARLDLLLTIAAQDAQRVAEGGASESRRNAIAQLLELFDRHDAAR
ILRSG

Sequences:

>Translated_725_residues
MKAVEHHVSGIILQDERDDNLGPLLAPLGSLPGVGPALAKLLARAVRGQRVIDLLFHLPESVVDRGLSPQLSRRPESVVD
HRYRPSLRNAVPGRGTTMQVRVRRFDAPARGTRVFFSPLEARRTGVGELVFLSPTQARQMRVGATVPVSGTLDAFGDRLQ
MAHPDHIVPGGDIDRIPALEPVWPLTAGLFPRHVRAALHQAFLRFPPLPEWLDSVLVARRHWPDFETALRQLHCPEAFPD
LLRGDAWQAAGERARQRLACDELLAEQVAMSEARRRNRNRPGRSIVGTGTLRAEALARFGYTPTGAQHRAVREIDSDLAA
SYPMMRLLQGDVGAGKTLVAMLAMLAAAEAGHQAVLMAPTEILARQHLATFQKLAPVPVAFLSGSVKGRARRTVLEDIAS
GRAPLVVGTHALFQDKVVFDDLALAVIDEQHRFGVEQRLLLGEKGDRADILVMTATPIPRTLLLTQWGEMQVSRLNEKPA
GRLPVRTSLHAMASLGDVLDGIGRAIARGALVFWVCPLVTESEAMDLAAAEARFAALTERFGPIVGLAHGQQDIAVREAA
IADFAAGRTKILVATTVIEVGVDIPAATIMVIEHAERFGLAQLHQLRGRVGRGRDESFCLLLHDDALGSTARRRLALLRD
TEDGFLIADEDFRLRGGGDVTGRRQSGLPDLRLATGARLDLLLTIAAQDAQRVAEGGASESRRNAIAQLLELFDRHDAAR
ILRSG
>Mature_725_residues
MKAVEHHVSGIILQDERDDNLGPLLAPLGSLPGVGPALAKLLARAVRGQRVIDLLFHLPESVVDRGLSPQLSRRPESVVD
HRYRPSLRNAVPGRGTTMQVRVRRFDAPARGTRVFFSPLEARRTGVGELVFLSPTQARQMRVGATVPVSGTLDAFGDRLQ
MAHPDHIVPGGDIDRIPALEPVWPLTAGLFPRHVRAALHQAFLRFPPLPEWLDSVLVARRHWPDFETALRQLHCPEAFPD
LLRGDAWQAAGERARQRLACDELLAEQVAMSEARRRNRNRPGRSIVGTGTLRAEALARFGYTPTGAQHRAVREIDSDLAA
SYPMMRLLQGDVGAGKTLVAMLAMLAAAEAGHQAVLMAPTEILARQHLATFQKLAPVPVAFLSGSVKGRARRTVLEDIAS
GRAPLVVGTHALFQDKVVFDDLALAVIDEQHRFGVEQRLLLGEKGDRADILVMTATPIPRTLLLTQWGEMQVSRLNEKPA
GRLPVRTSLHAMASLGDVLDGIGRAIARGALVFWVCPLVTESEAMDLAAAEARFAALTERFGPIVGLAHGQQDIAVREAA
IADFAAGRTKILVATTVIEVGVDIPAATIMVIEHAERFGLAQLHQLRGRVGRGRDESFCLLLHDDALGSTARRRLALLRD
TEDGFLIADEDFRLRGGGDVTGRRQSGLPDLRLATGARLDLLLTIAAQDAQRVAEGGASESRRNAIAQLLELFDRHDAAR
ILRSG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=668, Percent_Identity=39.6706586826347, Blast_Score=384, Evalue=1e-107,
Organism=Escherichia coli, GI1787357, Length=438, Percent_Identity=35.3881278538813, Blast_Score=230, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78910; Mature: 78910

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVEHHVSGIILQDERDDNLGPLLAPLGSLPGVGPALAKLLARAVRGQRVIDLLFHLPE
CCCHHHHHCEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCH
SVVDRGLSPQLSRRPESVVDHRYRPSLRNAVPGRGTTMQVRVRRFDAPARGTRVFFSPLE
HHHHCCCCCHHHCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCHH
ARRTGVGELVFLSPTQARQMRVGATVPVSGTLDAFGDRLQMAHPDHIVPGGDIDRIPALE
HHHCCCCCEEEECCCHHHHEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PVWPLTAGLFPRHVRAALHQAFLRFPPLPEWLDSVLVARRHWPDFETALRQLHCPEAFPD
CCCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
LLRGDAWQAAGERARQRLACDELLAEQVAMSEARRRNRNRPGRSIVGTGTLRAEALARFG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCC
YTPTGAQHRAVREIDSDLAASYPMMRLLQGDVGAGKTLVAMLAMLAAAEAGHQAVLMAPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECHH
EILARQHLATFQKLAPVPVAFLSGSVKGRARRTVLEDIASGRAPLVVGTHALFQDKVVFD
HHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHCCHHHH
DLALAVIDEQHRFGVEQRLLLGEKGDRADILVMTATPIPRTLLLTQWGEMQVSRLNEKPA
HHHHHHHCCHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCCCHHHHHHCCCCCC
GRLPVRTSLHAMASLGDVLDGIGRAIARGALVFWVCPLVTESEAMDLAAAEARFAALTER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGPIVGLAHGQQDIAVREAAIADFAAGRTKILVATTVIEVGVDIPAATIMVIEHAERFGL
HCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHH
AQLHQLRGRVGRGRDESFCLLLHDDALGSTARRRLALLRDTEDGFLIADEDFRLRGGGDV
HHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEECCCCC
TGRRQSGLPDLRLATGARLDLLLTIAAQDAQRVAEGGASESRRNAIAQLLELFDRHDAAR
CCCCCCCCCCCEECCCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ILRSG
HHHCC
>Mature Secondary Structure
MKAVEHHVSGIILQDERDDNLGPLLAPLGSLPGVGPALAKLLARAVRGQRVIDLLFHLPE
CCCHHHHHCEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCH
SVVDRGLSPQLSRRPESVVDHRYRPSLRNAVPGRGTTMQVRVRRFDAPARGTRVFFSPLE
HHHHCCCCCHHHCCCHHHHHCCCCCCHHHCCCCCCCEEEEEEEECCCCCCCCEEEECCHH
ARRTGVGELVFLSPTQARQMRVGATVPVSGTLDAFGDRLQMAHPDHIVPGGDIDRIPALE
HHHCCCCCEEEECCCHHHHEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PVWPLTAGLFPRHVRAALHQAFLRFPPLPEWLDSVLVARRHWPDFETALRQLHCPEAFPD
CCCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHH
LLRGDAWQAAGERARQRLACDELLAEQVAMSEARRRNRNRPGRSIVGTGTLRAEALARFG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCC
YTPTGAQHRAVREIDSDLAASYPMMRLLQGDVGAGKTLVAMLAMLAAAEAGHQAVLMAPT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEECHH
EILARQHLATFQKLAPVPVAFLSGSVKGRARRTVLEDIASGRAPLVVGTHALFQDKVVFD
HHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHCCHHHH
DLALAVIDEQHRFGVEQRLLLGEKGDRADILVMTATPIPRTLLLTQWGEMQVSRLNEKPA
HHHHHHHCCHHHCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHCCCHHHHHHCCCCCC
GRLPVRTSLHAMASLGDVLDGIGRAIARGALVFWVCPLVTESEAMDLAAAEARFAALTER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGPIVGLAHGQQDIAVREAAIADFAAGRTKILVATTVIEVGVDIPAATIMVIEHAERFGL
HCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHH
AQLHQLRGRVGRGRDESFCLLLHDDALGSTARRRLALLRDTEDGFLIADEDFRLRGGGDV
HHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHEECCCCEEEECCCEEEECCCCC
TGRRQSGLPDLRLATGARLDLLLTIAAQDAQRVAEGGASESRRNAIAQLLELFDRHDAAR
CCCCCCCCCCCEECCCCCEEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHH
ILRSG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]