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The map label for this gene is tlyC [H]

Identifier: 162147624

GI number: 162147624

Start: 1874018

End: 1874992

Strand: Reverse

Name: tlyC [H]

Synonym: GDI_1840

Alternate gene names: 162147624

Gene position: 1874992-1874018 (Counterclockwise)

Preceding gene: 162147625

Following gene: 162147623

Centisome position: 47.54

GC content: 69.03

Gene sequence:

>975_bases
GTGAACCGCCCCCTGCCCGTTTCCGCGACGTCGGACGCCGCGCCGCATCGCACCGATGCCCCCAAGGCGGAGACGGCCCG
CCCCCCCGATGAGGTCCCCCCGTCACGCCCGCGCGGCCGTGGACTGCTGTCGCTGTTCGGACGCAGGCGCGTCGAACAGG
GATTGCGCCATTCCATCGCCGCGCTGGTGCAGGAAGCCAACGACGCCGAGGGCGACGGCGCCGACCCCAATTCGGAACTG
GACCGCCAGGAACGCGCGCTGATCGCCAATGTGCTGCGCCTGCGCGGGATCACCGCCGACGACGTGATGGTGCCGCGCGC
CGACATCGTGGCCATGCCGGTCTCGCTGAGCCTGGACGAGGCCCTGGCCCTGATGCGGCGGGAAAACCATTCGCGCATGC
CGGTCTATCGCGAGCAGCTCGACGACATCGTGGGCATGATCCACGTGAAGGACCTGATCGCCTATGTCGGCACCAGCGAA
GGATTCAACGTGGAATCGCTGCTGCGCCAGCCGCTGATGGTGGCGCCGCAGATCCCGGTGCTGGACCTGCTGCTGCAGAT
GCGCCAGCGGCGCGTGCACCTGGCCCTGATCATCGACGAATATGGCGGCATCGACGGGCTGGTGACGATCGAGGACCTGG
TGGAAACCATCGTCGGCGACATCTCGGACGAACATGACGAACCGACGGCGGTCCTGATCCAGGAACGGCCGGACGGCACG
TTCGACGTCGATGCCCGCCTGCCGGTCGAGCAATTCGAATCCCGCCTGGGCCCGCTGCTGACCGATGCCGAGCGCGAGGC
CGAGATCGAGACCGTGGGTGGCCTGGTCTTCTACCTGGCCGGGCATGTGCCCACGCGCGGCGAGGTGCTGACCCATGACA
GCGGCCTGGTCTTCCGGGTGCTGGACGCGGATTCGCTGCATATCCGCAAGGTTCGCGTCCGCCCGCCGCCACCGCCGCCC
GCGCCAGCCGCCTGA

Upstream 100 bases:

>100_bases
GGATGGAAATGGAGGAAGCCCGGATCCTGGGCCGCCTGTCGGTGCCCAATCCCTGGAAATACCGCCCCGGCGCACCGTCG
GGGCTGATGGGGGACGGGCA

Downstream 100 bases:

>100_bases
TCCCCTATCCTTGTCGGTCCTGACCCGCCTCTTCCCCCTGTGGGCGATCCTGGTCTCGGCCTCGGCCATTCGCTGGCCGG
GGCCGTTCCTGGCGCTGTCG

Product: magnesium and cobalt efflux protein corC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNRPLPVSATSDAAPHRTDAPKAETARPPDEVPPSRPRGRGLLSLFGRRRVEQGLRHSIAALVQEANDAEGDGADPNSEL
DRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDEALALMRRENHSRMPVYREQLDDIVGMIHVKDLIAYVGTSE
GFNVESLLRQPLMVAPQIPVLDLLLQMRQRRVHLALIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGT
FDVDARLPVEQFESRLGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRVLDADSLHIRKVRVRPPPPPP
APAA

Sequences:

>Translated_324_residues
MNRPLPVSATSDAAPHRTDAPKAETARPPDEVPPSRPRGRGLLSLFGRRRVEQGLRHSIAALVQEANDAEGDGADPNSEL
DRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDEALALMRRENHSRMPVYREQLDDIVGMIHVKDLIAYVGTSE
GFNVESLLRQPLMVAPQIPVLDLLLQMRQRRVHLALIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGT
FDVDARLPVEQFESRLGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRVLDADSLHIRKVRVRPPPPPP
APAA
>Mature_324_residues
MNRPLPVSATSDAAPHRTDAPKAETARPPDEVPPSRPRGRGLLSLFGRRRVEQGLRHSIAALVQEANDAEGDGADPNSEL
DRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDEALALMRRENHSRMPVYREQLDDIVGMIHVKDLIAYVGTSE
GFNVESLLRQPLMVAPQIPVLDLLLQMRQRRVHLALIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGT
FDVDARLPVEQFESRLGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRVLDADSLHIRKVRVRPPPPPP
APAA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=223, Percent_Identity=28.2511210762332, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI40068049, Length=179, Percent_Identity=31.2849162011173, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1786879, Length=247, Percent_Identity=36.0323886639676, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082033, Length=291, Percent_Identity=30.9278350515464, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693175, Length=253, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788119, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790664, Length=239, Percent_Identity=25.1046025104602, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 35604; Mature: 35604

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPLPVSATSDAAPHRTDAPKAETARPPDEVPPSRPRGRGLLSLFGRRRVEQGLRHSIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALVQEANDAEGDGADPNSELDRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDE
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCHHH
ALALMRRENHSRMPVYREQLDDIVGMIHVKDLIAYVGTSEGFNVESLLRQPLMVAPQIPV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCCH
LDLLLQMRQRRVHLALIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGT
HHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FDVDARLPVEQFESRLGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRV
EECCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEE
LDADSLHIRKVRVRPPPPPPAPAA
ECCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MNRPLPVSATSDAAPHRTDAPKAETARPPDEVPPSRPRGRGLLSLFGRRRVEQGLRHSIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALVQEANDAEGDGADPNSELDRQERALIANVLRLRGITADDVMVPRADIVAMPVSLSLDE
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCHHH
ALALMRRENHSRMPVYREQLDDIVGMIHVKDLIAYVGTSEGFNVESLLRQPLMVAPQIPV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCCH
LDLLLQMRQRRVHLALIIDEYGGIDGLVTIEDLVETIVGDISDEHDEPTAVLIQERPDGT
HHHHHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FDVDARLPVEQFESRLGPLLTDAEREAEIETVGGLVFYLAGHVPTRGEVLTHDSGLVFRV
EECCCCCCHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEE
LDADSLHIRKVRVRPPPPPPAPAA
ECCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA