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The map label for this gene is moaE [H]

Identifier: 162147606

GI number: 162147606

Start: 1854435

End: 1854893

Strand: Direct

Name: moaE [H]

Synonym: GDI_1822

Alternate gene names: 162147606

Gene position: 1854435-1854893 (Clockwise)

Preceding gene: 162147605

Following gene: 162147607

Centisome position: 47.02

GC content: 70.81

Gene sequence:

>459_bases
ATGCGGGTCGATGTCCGGGTCCAGGCCGACCCGTTTTCCCTGGACGTGGAAACCGCCCGGCTGACGCGGGACGGGCACGA
TATCGGGGGGATGGGTATGTTCCTGGGGGTCGTGCGGGGCGGCGACGGGCTGGCGGCGCTGACGCTGGAACATTACCCGG
GCATGACCGAATCCATGATCGCGCGAATCGTCCACGAGGCCGGCGCGCGATTCGGCCTGCTGGCCTGCACGGTCATCCAT
CGTGTCGGACGGCTGGAGGTCGGCGCGCCGATCGTGCTGGTGCTGTGTGCCGCCGCCCATCGCGGCGCGGCGCTGGAGGC
CACGTCCTTCGTCATCGACTGGCTGAAGACCCGGGCCCCGTTCTGGAAGCGCGAGGACCGCGCCGATGGAAGCAGCGCCT
GGGTCGAAGCGCGCGAAAGCGACGAGGCCGCGGCCACGCGCTGGGGTCCGGTCGGCTGA

Upstream 100 bases:

>100_bases
GATCCGCTGCGCAGTCAACCAGGAATTCGCCAGTCACGCGGACCACGTGGGGCCGGGTGACGAACTGGCCTTCTTCCCGC
CGGTCACAGGGGGATAGGGC

Downstream 100 bases:

>100_bases
CGCGGCACGCGCGGGGCGATTCGCTCCGCGACGCGGCCGGGGGAAGAAAAAAAACATTTCCCTTGACCCGAGGAAAGCCG
GGGAAAGTTTTGAATCCGCT

Product: molybdopterin-converting factor subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRVDVRVQADPFSLDVETARLTRDGHDIGGMGMFLGVVRGGDGLAALTLEHYPGMTESMIARIVHEAGARFGLLACTVIH
RVGRLEVGAPIVLVLCAAAHRGAALEATSFVIDWLKTRAPFWKREDRADGSSAWVEARESDEAAATRWGPVG

Sequences:

>Translated_152_residues
MRVDVRVQADPFSLDVETARLTRDGHDIGGMGMFLGVVRGGDGLAALTLEHYPGMTESMIARIVHEAGARFGLLACTVIH
RVGRLEVGAPIVLVLCAAAHRGAALEATSFVIDWLKTRAPFWKREDRADGSSAWVEARESDEAAATRWGPVG
>Mature_152_residues
MRVDVRVQADPFSLDVETARLTRDGHDIGGMGMFLGVVRGGDGLAALTLEHYPGMTESMIARIVHEAGARFGLLACTVIH
RVGRLEVGAPIVLVLCAAAHRGAALEATSFVIDWLKTRAPFWKREDRADGSSAWVEARESDEAAATRWGPVG

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=109, Percent_Identity=32.1100917431193, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1787003, Length=145, Percent_Identity=52.4137931034483, Blast_Score=132, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356259, Length=126, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16367; Mature: 16367

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVDVRVQADPFSLDVETARLTRDGHDIGGMGMFLGVVRGGDGLAALTLEHYPGMTESMI
CCEEEEEECCCCEEEHHHHHHCCCCCCCCCHHHHHHEEECCCCEEEEEECCCCCCHHHHH
ARIVHEAGARFGLLACTVIHRVGRLEVGAPIVLVLCAAAHRGAALEATSFVIDWLKTRAP
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
FWKREDRADGSSAWVEARESDEAAATRWGPVG
CCCCCCCCCCCHHEEECCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRVDVRVQADPFSLDVETARLTRDGHDIGGMGMFLGVVRGGDGLAALTLEHYPGMTESMI
CCEEEEEECCCCEEEHHHHHHCCCCCCCCCHHHHHHEEECCCCEEEEEECCCCCCHHHHH
ARIVHEAGARFGLLACTVIHRVGRLEVGAPIVLVLCAAAHRGAALEATSFVIDWLKTRAP
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
FWKREDRADGSSAWVEARESDEAAATRWGPVG
CCCCCCCCCCCHHEEECCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]