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The map label for this gene is pgsA [H]

Identifier: 162147603

GI number: 162147603

Start: 1852929

End: 1853525

Strand: Direct

Name: pgsA [H]

Synonym: GDI_1819

Alternate gene names: 162147603

Gene position: 1852929-1853525 (Clockwise)

Preceding gene: 162147602

Following gene: 162147604

Centisome position: 46.98

GC content: 64.82

Gene sequence:

>597_bases
ATGCTGACCGACCTGCCCAATATCCTGACCTTGTCGCGGATTGTGCAGATTCCCGTTCTGGTGGCCATTGTGGCGATAGG
GGCTCCGGTCACGGATTGTGCGGCGTGCCTGCTGTTCATCGCCGCCGGCATCACCGATTACCTGGACGGCAAGCTGGCGC
GTGCCTGGCATCAATATTCCGACCTGGGCCGGATGCTGGACCCGATCGCCGACAAGCTGCTGGTGGGCGCGTCGCTGATG
ATGCTGGCCGGATGCGACCGTCTGCCGTTCGGGTCGCTGTATCCCGCCATCATCATCCTGGCGCGGGAGATCCTGATCAG
CGGGCTGCGCGAATTCCTGGCCTCGACCCGTATCAGCCTTCCGGTCACGCGGCTGGCGAAATGGAAGACCGGCATCCAGA
TGACCGCGATCGGCTTCCTGCTGGCGGGTGACAGCACGGGGCGGCTGCTGCACCTGGAATGGATGCACGTCGGCACGGTC
GGGGCCGTCCTGTTGTGGATTGCCGCGGCGCTGACCGTCCTGACGGGATGGGATTACCTGCTGACCGGGCTGCGTCATGT
GGGCCGGAATGGCGGGGTGTCGAAAATCGCCCCCTGA

Upstream 100 bases:

>100_bases
GCAAGAAGGGTGTACGGTCTGCCAGGCGTGAGCAAATTCGTCATCAGACCGTCGTGAAGAGCCGTTCCTGTCCCCCTCGT
GTTGTTGTACTGTTACCGCG

Downstream 100 bases:

>100_bases
TTGTATCTCTATGTTCTATGCTACTTGAGGTTGCGGTGAGGAATGGGCAGACTTCCTCTTGCCGGCGAACGGGGTTGCCG
AGGGGGAGGGGGACGATGCG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferas

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MLTDLPNILTLSRIVQIPVLVAIVAIGAPVTDCAACLLFIAAGITDYLDGKLARAWHQYSDLGRMLDPIADKLLVGASLM
MLAGCDRLPFGSLYPAIIILAREILISGLREFLASTRISLPVTRLAKWKTGIQMTAIGFLLAGDSTGRLLHLEWMHVGTV
GAVLLWIAAALTVLTGWDYLLTGLRHVGRNGGVSKIAP

Sequences:

>Translated_198_residues
MLTDLPNILTLSRIVQIPVLVAIVAIGAPVTDCAACLLFIAAGITDYLDGKLARAWHQYSDLGRMLDPIADKLLVGASLM
MLAGCDRLPFGSLYPAIIILAREILISGLREFLASTRISLPVTRLAKWKTGIQMTAIGFLLAGDSTGRLLHLEWMHVGTV
GAVLLWIAAALTVLTGWDYLLTGLRHVGRNGGVSKIAP
>Mature_198_residues
MLTDLPNILTLSRIVQIPVLVAIVAIGAPVTDCAACLLFIAAGITDYLDGKLARAWHQYSDLGRMLDPIADKLLVGASLM
MLAGCDRLPFGSLYPAIIILAREILISGLREFLASTRISLPVTRLAKWKTGIQMTAIGFLLAGDSTGRLLHLEWMHVGTV
GAVLLWIAAALTVLTGWDYLLTGLRHVGRNGGVSKIAP

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=182, Percent_Identity=35.7142857142857, Blast_Score=101, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24650130, Length=155, Percent_Identity=34.1935483870968, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650126, Length=155, Percent_Identity=34.1935483870968, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650128, Length=155, Percent_Identity=34.1935483870968, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21226; Mature: 21226

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDLPNILTLSRIVQIPVLVAIVAIGAPVTDCAACLLFIAAGITDYLDGKLARAWHQYS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGRMLDPIADKLLVGASLMMLAGCDRLPFGSLYPAIIILAREILISGLREFLASTRISL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVTRLAKWKTGIQMTAIGFLLAGDSTGRLLHLEWMHVGTVGAVLLWIAAALTVLTGWDYL
HHHHHHHHHCCCHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLRHVGRNGGVSKIAP
HHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLTDLPNILTLSRIVQIPVLVAIVAIGAPVTDCAACLLFIAAGITDYLDGKLARAWHQYS
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGRMLDPIADKLLVGASLMMLAGCDRLPFGSLYPAIIILAREILISGLREFLASTRISL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVTRLAKWKTGIQMTAIGFLLAGDSTGRLLHLEWMHVGTVGAVLLWIAAALTVLTGWDYL
HHHHHHHHHCCCHHHHHHHHEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLRHVGRNGGVSKIAP
HHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA