Click here to switch to the map view.

The map label for this gene is bacA

Identifier: 162147575

GI number: 162147575

Start: 1823145

End: 1824002

Strand: Reverse

Name: bacA

Synonym: GDI_1791

Alternate gene names: 162147575

Gene position: 1824002-1823145 (Counterclockwise)

Preceding gene: 162147577

Following gene: 162147574

Centisome position: 46.25

GC content: 66.43

Gene sequence:

>858_bases
ATGGACAGCCGGACAATGACACTCATCCAAGCCATCGTGATCGCGATCCTCCAGGGGGCGACGGAGCTGTTCCCGGTCAG
CAGCCTGGGGCATGCCGTCATCGTCCCCGCCCTGCTGGGCTGGGCGTTCGACCCGCACGGCGAAATCTTCCTGCCGTTCC
TGGTCATGCTGCACCTGGGCACCGCGATCGCCCTGCTGGTCTATTTCCGCAATGACTGGGCGGCCATCTTCCAGGGGCTG
AGGGGCCGCGACGGCAGCCAGCGCCAGGCCGAAAGCATCCATATCCTGGCCCTGCTGGTGGTGGCGACCATTCCGGCGGT
CATTATCGGCGGCCTGCTGGAACATTGGCTGCGGGCGCTGTTCGGCACCGCGCGCTATGCCGCGATCTTCCTGTTCCTGA
ACGGCCTGCTGCTGCTGCTGACCGAACGGATGAAGAGCCGCCAGCCCGTCCAGGGCGGCTATGCCATCGCATCGCTGACC
TATGCCGACGCCGCGATCATCGGCCTGTGGCAGTGCCTGGCCTTCCTGCCCGGCATCTCGCGGTCGGGGGCCACGATCAT
CGGCGCGCTGTTTCGCGGCCTGAACCATGAAGGGGCCGCGCGGTTTTCGTTCCTGATGGCCCAGCCGGTCATCATTGCCG
CCACGGTGCGCGAGGCCCTGCACATGCGCCATGTCGCCATCCCGCCGGGTCAGATGCAGGTCGCGACCATCGGCGCCATG
GTGGCGGCCGTGACCGCACTGGCCAGCACCGCGTTCCTGATGCGATACTTCCACAATCACGAGCGATGGGCGCTGAGCCC
GTTCGGCTATTACTGCGTGCTGGCCGGCGCGGTTTCCTTCTTCATCCTCGGCCACTGA

Upstream 100 bases:

>100_bases
AACGTTCCTCCTTATTCCTGTCGGGCCGATCATTCGCGGCGCTACGGTACAGACTTGCCGGGCACCCGGAAAGTAAGGCA
CGACGACATTCTAATTCGCC

Downstream 100 bases:

>100_bases
ACGTACCCTCCCCCATGATACGCCGCCTGACCGCCAGGTCCCTCCTGGCACTGCCCCTTCTGCTGCTTGCCGGCCTGGGT
ACCGCCCGTGCGACGCCCCC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MDSRTMTLIQAIVIAILQGATELFPVSSLGHAVIVPALLGWAFDPHGEIFLPFLVMLHLGTAIALLVYFRNDWAAIFQGL
RGRDGSQRQAESIHILALLVVATIPAVIIGGLLEHWLRALFGTARYAAIFLFLNGLLLLLTERMKSRQPVQGGYAIASLT
YADAAIIGLWQCLAFLPGISRSGATIIGALFRGLNHEGAARFSFLMAQPVIIAATVREALHMRHVAIPPGQMQVATIGAM
VAAVTALASTAFLMRYFHNHERWALSPFGYYCVLAGAVSFFILGH

Sequences:

>Translated_285_residues
MDSRTMTLIQAIVIAILQGATELFPVSSLGHAVIVPALLGWAFDPHGEIFLPFLVMLHLGTAIALLVYFRNDWAAIFQGL
RGRDGSQRQAESIHILALLVVATIPAVIIGGLLEHWLRALFGTARYAAIFLFLNGLLLLLTERMKSRQPVQGGYAIASLT
YADAAIIGLWQCLAFLPGISRSGATIIGALFRGLNHEGAARFSFLMAQPVIIAATVREALHMRHVAIPPGQMQVATIGAM
VAAVTALASTAFLMRYFHNHERWALSPFGYYCVLAGAVSFFILGH
>Mature_285_residues
MDSRTMTLIQAIVIAILQGATELFPVSSLGHAVIVPALLGWAFDPHGEIFLPFLVMLHLGTAIALLVYFRNDWAAIFQGL
RGRDGSQRQAESIHILALLVVATIPAVIIGGLLEHWLRALFGTARYAAIFLFLNGLLLLLTERMKSRQPVQGGYAIASLT
YADAAIIGLWQCLAFLPGISRSGATIIGALFRGLNHEGAARFSFLMAQPVIIAATVREALHMRHVAIPPGQMQVATIGAM
VAAVTALASTAFLMRYFHNHERWALSPFGYYCVLAGAVSFFILGH

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=275, Percent_Identity=33.4545454545455, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_GLUDA (A9HI81)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001602036.1
- RefSeq:   YP_002274437.1
- GeneID:   5790045
- GeneID:   6973409
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_0020
- HOGENOM:   HBG391969
- OMA:   VMLHLGT
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30875; Mature: 30875

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14fd6524)-; HASH(0x147debec)-; HASH(0x15ca9a5c)-; HASH(0x159425f4)-; HASH(0x159b10b8)-; HASH(0x159b0f44)-; HASH(0x15ccb1c4)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRTMTLIQAIVIAILQGATELFPVSSLGHAVIVPALLGWAFDPHGEIFLPFLVMLHLG
CCCHHHHHHHHHHHHHHHCHHHHCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TAIALLVYFRNDWAAIFQGLRGRDGSQRQAESIHILALLVVATIPAVIIGGLLEHWLRAL
HHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGTARYAAIFLFLNGLLLLLTERMKSRQPVQGGYAIASLTYADAAIIGLWQCLAFLPGIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSGATIIGALFRGLNHEGAARFSFLMAQPVIIAATVREALHMRHVAIPPGQMQVATIGAM
CCCHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAAVTALASTAFLMRYFHNHERWALSPFGYYCVLAGAVSFFILGH
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDSRTMTLIQAIVIAILQGATELFPVSSLGHAVIVPALLGWAFDPHGEIFLPFLVMLHLG
CCCHHHHHHHHHHHHHHHCHHHHCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TAIALLVYFRNDWAAIFQGLRGRDGSQRQAESIHILALLVVATIPAVIIGGLLEHWLRAL
HHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGTARYAAIFLFLNGLLLLLTERMKSRQPVQGGYAIASLTYADAAIIGLWQCLAFLPGIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RSGATIIGALFRGLNHEGAARFSFLMAQPVIIAATVREALHMRHVAIPPGQMQVATIGAM
CCCHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VAAVTALASTAFLMRYFHNHERWALSPFGYYCVLAGAVSFFILGH
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA