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The map label for this gene is tyrA [H]

Identifier: 162147412

GI number: 162147412

Start: 1638272

End: 1639180

Strand: Direct

Name: tyrA [H]

Synonym: GDI_1627

Alternate gene names: 162147412

Gene position: 1638272-1639180 (Clockwise)

Preceding gene: 162147411

Following gene: 162147416

Centisome position: 41.54

GC content: 70.74

Gene sequence:

>909_bases
ATGACCGATCCCTCGCCCGCCGCGCCGCAGCCCCTGTTCCGCACGCTTGCCGTCATCGGGCCGGGCCTGATCGGATCGTC
CATCCTGCGCCGCGCGCGGCAGGACGGCACGATCGCGGCCGAACTGGTGGCGTGCGACGTCGAGCCCGACGTCTGCCGCC
GGGTGCGCGACCTGGACCTGGCCGACCGGGTGGAGCAGGACGCGCTGCGTGCGGTGGCGGATGCCGACTGCGTCATCCTG
TGCGTGCCGGTGGGCGCGATCGCCACCGTGGGCGCCATGGTGCTGCCGGCCATGAAGCCCGGCGCGATCCTCAGCGAGGT
CGGATCGACCAAGCAGTCGATCATCGGCGCCATCGCCCCCGCACTGCGCGCCGACATCGCGTTCGTGCCGACCCATCCGA
TGGCGGGCACGGAATATTCGGGCCCCGACGCGGGATTCGCCACCCTGTTCGACGACCGGTGGTGCCTGCTGACGCCGCTG
GAGGACACGGACCCGGCCGCGATCGCGACCATCGAGACGCTGTGGCACCGCATGGGCGCGCGCACTCGGATCATTGACCC
GGCCCATCACGACCGGGTCTGCGCCATCGTCAGCCACCTGCCGCACCTGCTGGCCTTCACCATCTGCGGCACCGCCGACG
ACCTGGCCGACGAAACGCGGTCCGAGGTCCTGGATTTCGCGGCGTCGGGCTTTCGCGACTTTACCCGCATCGCCGCGTCC
GACCCGGTGATGTGGCGCGACATCTTCCTGAACAACCGCGAGGCGCTGCTGGAAATGCTGGCCCGCTTCATGGAGGACGC
CCAGGCCATGGCCCGGGCGATCCGATGGGGCGACGAGGCGTTCATCGTGGACCGGATCGAACGCGGCCGCCACATCCGGC
GCAGCCTGCTGGAAAACCGCCAGGCCTGA

Upstream 100 bases:

>100_bases
TGGGACCGGCCACGGCGCTGGCCCAGACCAAGGCATTGGCCCAGGACCCGGACGGCGGTGCCTATGCCGCGTCCGAACGG
TCGCGCTGACCGGATACGCC

Downstream 100 bases:

>100_bases
AACGAACAGGGGTCAAGGGGTCCGCGACCCCTTGCGGGTTCGGGCAGAGCCCGACCTTCCTCCCCCCTCAGGCGTCCGGC
GCGTAGGTCGGGCTGTAGGT

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTDPSPAAPQPLFRTLAVIGPGLIGSSILRRARQDGTIAAELVACDVEPDVCRRVRDLDLADRVEQDALRAVADADCVIL
CVPVGAIATVGAMVLPAMKPGAILSEVGSTKQSIIGAIAPALRADIAFVPTHPMAGTEYSGPDAGFATLFDDRWCLLTPL
EDTDPAAIATIETLWHRMGARTRIIDPAHHDRVCAIVSHLPHLLAFTICGTADDLADETRSEVLDFAASGFRDFTRIAAS
DPVMWRDIFLNNREALLEMLARFMEDAQAMARAIRWGDEAFIVDRIERGRHIRRSLLENRQA

Sequences:

>Translated_302_residues
MTDPSPAAPQPLFRTLAVIGPGLIGSSILRRARQDGTIAAELVACDVEPDVCRRVRDLDLADRVEQDALRAVADADCVIL
CVPVGAIATVGAMVLPAMKPGAILSEVGSTKQSIIGAIAPALRADIAFVPTHPMAGTEYSGPDAGFATLFDDRWCLLTPL
EDTDPAAIATIETLWHRMGARTRIIDPAHHDRVCAIVSHLPHLLAFTICGTADDLADETRSEVLDFAASGFRDFTRIAAS
DPVMWRDIFLNNREALLEMLARFMEDAQAMARAIRWGDEAFIVDRIERGRHIRRSLLENRQA
>Mature_301_residues
TDPSPAAPQPLFRTLAVIGPGLIGSSILRRARQDGTIAAELVACDVEPDVCRRVRDLDLADRVEQDALRAVADADCVILC
VPVGAIATVGAMVLPAMKPGAILSEVGSTKQSIIGAIAPALRADIAFVPTHPMAGTEYSGPDAGFATLFDDRWCLLTPLE
DTDPAAIATIETLWHRMGARTRIIDPAHHDRVCAIVSHLPHLLAFTICGTADDLADETRSEVLDFAASGFRDFTRIAASD
PVMWRDIFLNNREALLEMLARFMEDAQAMARAIRWGDEAFIVDRIERGRHIRRSLLENRQA

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 32870; Mature: 32739

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPSPAAPQPLFRTLAVIGPGLIGSSILRRARQDGTIAAELVACDVEPDVCRRVRDLDL
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHEEECCCHHHHHHHHCCCH
ADRVEQDALRAVADADCVILCVPVGAIATVGAMVLPAMKPGAILSEVGSTKQSIIGAIAP
HHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHH
ALRADIAFVPTHPMAGTEYSGPDAGFATLFDDRWCLLTPLEDTDPAAIATIETLWHRMGA
HHHHCEEEECCCCCCCCCCCCCCCCHHHEECCCEEEEECCCCCCCHHHHHHHHHHHHHCC
RTRIIDPAHHDRVCAIVSHLPHLLAFTICGTADDLADETRSEVLDFAASGFRDFTRIAAS
CCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPVMWRDIFLNNREALLEMLARFMEDAQAMARAIRWGDEAFIVDRIERGRHIRRSLLENR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QA
CC
>Mature Secondary Structure 
TDPSPAAPQPLFRTLAVIGPGLIGSSILRRARQDGTIAAELVACDVEPDVCRRVRDLDL
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEHEEECCCHHHHHHHHCCCH
ADRVEQDALRAVADADCVILCVPVGAIATVGAMVLPAMKPGAILSEVGSTKQSIIGAIAP
HHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHH
ALRADIAFVPTHPMAGTEYSGPDAGFATLFDDRWCLLTPLEDTDPAAIATIETLWHRMGA
HHHHCEEEECCCCCCCCCCCCCCCCHHHEECCCEEEEECCCCCCCHHHHHHHHHHHHHCC
RTRIIDPAHHDRVCAIVSHLPHLLAFTICGTADDLADETRSEVLDFAASGFRDFTRIAAS
CCEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPVMWRDIFLNNREALLEMLARFMEDAQAMARAIRWGDEAFIVDRIERGRHIRRSLLENR
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]