Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 162147357

GI number: 162147357

Start: 1572750

End: 1573436

Strand: Direct

Name: kdpE [H]

Synonym: GDI_1567

Alternate gene names: 162147357

Gene position: 1572750-1573436 (Clockwise)

Preceding gene: 162147356

Following gene: 162147359

Centisome position: 39.88

GC content: 57.35

Gene sequence:

>687_bases
ATGAGCGCTCCGCGTGTCCTCGTTGTCGATGACGAACCTGCCATCCGGCGTCTTCTGAGAACCAGTCTTGCGACCCAGGA
CTGGCGCGTGATCGAGGCCGGAAACGGCATAAGCGCACTGGCTGCAGTGAAAGCTGAAGAGATCGACGTCGTGCTGCTTG
ATCTGGGGCTGCCAGACATGGACGGCATCGAAGTTATTCGCCAGATACGCCTGGTGTTGCCCACCTTGCCGATTGTCGTA
CTTTCGGTGCGCGACGATGAACGGGGCAAGGTCGCGGCCCTGGACCTGGGTGCGGATGATTATGTCACCAAACCTTTCGG
CATGGCCGAACTGGTCGCCAGGCTGCGCGCAGCACTCAGGCATGCCCTTCAGAAAGAAGGCACGATTCCGCTGTATGTCT
CGGGTGACCTCAGTGTGGATCTCGTGCGCCGTATCGTGACCCGCAGCGGTGAGGAAGTGCATCTTTCGCCGCGAGAATGG
GATATTCTACGGCTTCTGATCCGCCATGCGGGACGTGTCCTGACTCATAAGCATATATTAGGGCAGCTCTGGGGTGCGAA
CGGAGATGTCCAGCAGTTAAGGGTGTATATTCGTCAGCTTCGCCAGAAGCTGGAAATTAACCCTGAGAGGCCAAGGCATA
TTATTACCGAGACTGGGATTGGATACCGCCTGACCCTTGTGGAGTGA

Upstream 100 bases:

>100_bases
TTGTCGAAACTGCGGGTGGTTCGATCACAGCGGAAAATCGTCCCGATCGCACAGGAGCCGTATTTACGCTAAGTTTTCCG
ATTGTAGCGGAGGTATCAGG

Downstream 100 bases:

>100_bases
CGTCACTCCAACGCTGGATCGCTGTCTAAGAGCCCGATCCGAAAGTTTTTGAACAATACCAGCCTGTTGTGATTCATCCG
TCTTTGCGAAGAGATGGAGT

Product: KdpE family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSAPRVLVVDDEPAIRRLLRTSLATQDWRVIEAGNGISALAAVKAEEIDVVLLDLGLPDMDGIEVIRQIRLVLPTLPIVV
LSVRDDERGKVAALDLGADDYVTKPFGMAELVARLRAALRHALQKEGTIPLYVSGDLSVDLVRRIVTRSGEEVHLSPREW
DILRLLIRHAGRVLTHKHILGQLWGANGDVQQLRVYIRQLRQKLEINPERPRHIITETGIGYRLTLVE

Sequences:

>Translated_228_residues
MSAPRVLVVDDEPAIRRLLRTSLATQDWRVIEAGNGISALAAVKAEEIDVVLLDLGLPDMDGIEVIRQIRLVLPTLPIVV
LSVRDDERGKVAALDLGADDYVTKPFGMAELVARLRAALRHALQKEGTIPLYVSGDLSVDLVRRIVTRSGEEVHLSPREW
DILRLLIRHAGRVLTHKHILGQLWGANGDVQQLRVYIRQLRQKLEINPERPRHIITETGIGYRLTLVE
>Mature_227_residues
SAPRVLVVDDEPAIRRLLRTSLATQDWRVIEAGNGISALAAVKAEEIDVVLLDLGLPDMDGIEVIRQIRLVLPTLPIVVL
SVRDDERGKVAALDLGADDYVTKPFGMAELVARLRAALRHALQKEGTIPLYVSGDLSVDLVRRIVTRSGEEVHLSPREWD
ILRLLIRHAGRVLTHKHILGQLWGANGDVQQLRVYIRQLRQKLEINPERPRHIITETGIGYRLTLVE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=50.6726457399103, Blast_Score=209, Evalue=9e-56,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.920704845815, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=35.5263157894737, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=34.070796460177, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.7017543859649, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=30.8370044052863, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.3571428571429, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=26.9230769230769, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=28.1938325991189, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=30.5676855895196, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=37.3983739837398, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=30.3964757709251, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=35, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788191, Length=115, Percent_Identity=33.9130434782609, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25547; Mature: 25416

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPRVLVVDDEPAIRRLLRTSLATQDWRVIEAGNGISALAAVKAEEIDVVLLDLGLPDM
CCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCCC
DGIEVIRQIRLVLPTLPIVVLSVRDDERGKVAALDLGADDYVTKPFGMAELVARLRAALR
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HALQKEGTIPLYVSGDLSVDLVRRIVTRSGEEVHLSPREWDILRLLIRHAGRVLTHKHIL
HHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHH
GQLWGANGDVQQLRVYIRQLRQKLEINPERPRHIITETGIGYRLTLVE
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEC
>Mature Secondary Structure 
SAPRVLVVDDEPAIRRLLRTSLATQDWRVIEAGNGISALAAVKAEEIDVVLLDLGLPDM
CCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEECCCCCC
DGIEVIRQIRLVLPTLPIVVLSVRDDERGKVAALDLGADDYVTKPFGMAELVARLRAALR
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HALQKEGTIPLYVSGDLSVDLVRRIVTRSGEEVHLSPREWDILRLLIRHAGRVLTHKHIL
HHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHH
GQLWGANGDVQQLRVYIRQLRQKLEINPERPRHIITETGIGYRLTLVE
HHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]