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The map label for this gene is alkJ [C]

Identifier: 162147323

GI number: 162147323

Start: 1538335

End: 1539930

Strand: Direct

Name: alkJ [C]

Synonym: GDI_1529

Alternate gene names: 162147323

Gene position: 1538335-1539930 (Clockwise)

Preceding gene: 162147322

Following gene: 162147324

Centisome position: 39.0

GC content: 65.41

Gene sequence:

>1596_bases
ATGACCGAAAGCTGTGACTATCTCGTCATCGGCGGGGGGTCGGCGGGCTGCGTCATGGCGGCGCTGCTGTCGGAAAATCC
GGCGGCGCGCGTATGCATGATCGAGGCCGGCGGCCCCGATACCAATCCCCTGATCCACATCCCGATCGGCTTCGCCAAGA
TGACGACGGGACCGCTGACCTGGGGGCTGGCCACTGCGCCGCAGAAGCACGCCAACAATCGTGAAATCCCTTATGTGCAG
GCCAAGGTCCTGGGCGGTGGGTCCTCGATCAATGCCGAAGTCTTCACGCGCGGCGTTCCGTCGGATTATGACCGCTGGGT
GGAGGAAGGCGCCGAGGGCTGGGCCTTCAAGGACATCCAGAAATACCTGATCCGGTCCGAGGGCAATACGGCGCTGTCGG
GCGAATGGCATGGCACGAACGGCCCGCTGGGCGTGTCCAACCCGACCTCGCCCAATCCGCTCAGCCTCGCCTTCGTGCAG
AGCTGCCAGGAATACGGCATTCCGTACAATCCCGACTTCAACGGCCCCAGGCAGGAAGGGGCCGGATTCTACCAGTTGAC
GGTCCGCAACAGCCGGCGCTGCTCGGCGGCGGTCGGCTATCTGCGTCCGGCGCGCAAGCGCGCCAACCTGCATGTCATCA
CCAGGGCGCAGGTCCTGCGCATCGCCTTCGAGGGCAAGCGCGCGAAGGGCGTCGTCTATGCGGTGGATGGCCAGGTCCGG
GAAGTGCGGGCGGAACAGGAAGTCATCGTCACCTCCGGCGCCATCGGCACGCCGAAACTGCTGATGCTGTCGGGCATCGG
GCCGGCCGCGCACCTGCAGGCCCATGACGTTCCGGTGGTGCATGACCTGCCGGGCGTCGGCCAGAACCTGCAGGACCATT
TCGGCGTGGATATCGTCGCCGAACTGAAAGATCACGAAAGCTACAACCGGTACAACAAATATCACTGGGCGGCGTGGGCC
GGCCTGCAATACGCGCTGTTCCGCTCGGGTCCGCTGGCGTCCAACGTCGTGGAAGGCGGCGCGTTCTGGTATGCGGACCG
CAACGCGCGCACGCCCGACCTGCAATTCCACTTCCTGGCCGGCGCGGGGGCGGAAGCCGGGGTGGTCTCGGTGCCGAAGG
GCGCGTCCGGCATTACCCTCAACAGCTACACGCTGCGCCCGAAATCGCGTGGCACGGTCACGCTGCGGTCGTCCGACCCC
CGGGACAACCCGATCGTCGATCCGAACTTCCTGGCCGACCCCGACGACCTGCGCATCTCGGCCGAAGGCGTGAAGATCAG
CGTGGAGATGTTCCGCCAACCGTCGCTGCAGAAATACATCAAGTCGATCAACCTGTTCGACGAGATCCGGCCGACGGCCC
GCACCTACGAGGACTACACCCGGCAGAACGGCCGGACATCCTATCACCCCACCTGCACCTGCAAGATGGGCAAGGACCCG
ATGGCGGTGGTCGATTCGCAGCTTCGCATCCACGGGCTGGACGGCATCCGCATCTGCGACAGCTCGGTCATGCCGTCGCT
GATCGGATCGAATACCAACGCGCCGACGATCATGATCGCCGAGCGCGCCGCCGACCTGATCCGGGGCAATGCCTAG

Upstream 100 bases:

>100_bases
CGGGCTGGGGGCGCGAGACCGGCGTCCTGGGGGTCGAGGAATATACGCAGGTCAAGGCCGTCCACGTGGATATCGGCCCG
CGCGCGCACTGGATCGAATC

Downstream 100 bases:

>100_bases
GCTCGGTCGGGTCCGGTAAAGTATCTAACCAGATAGTTTTCAAGAGAGACGCACCATGTCGAAAGTCAAGCAGGCCGCGG
ACGTCGCAACGCTGATCAGG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTESCDYLVIGGGSAGCVMAALLSENPAARVCMIEAGGPDTNPLIHIPIGFAKMTTGPLTWGLATAPQKHANNREIPYVQ
AKVLGGGSSINAEVFTRGVPSDYDRWVEEGAEGWAFKDIQKYLIRSEGNTALSGEWHGTNGPLGVSNPTSPNPLSLAFVQ
SCQEYGIPYNPDFNGPRQEGAGFYQLTVRNSRRCSAAVGYLRPARKRANLHVITRAQVLRIAFEGKRAKGVVYAVDGQVR
EVRAEQEVIVTSGAIGTPKLLMLSGIGPAAHLQAHDVPVVHDLPGVGQNLQDHFGVDIVAELKDHESYNRYNKYHWAAWA
GLQYALFRSGPLASNVVEGGAFWYADRNARTPDLQFHFLAGAGAEAGVVSVPKGASGITLNSYTLRPKSRGTVTLRSSDP
RDNPIVDPNFLADPDDLRISAEGVKISVEMFRQPSLQKYIKSINLFDEIRPTARTYEDYTRQNGRTSYHPTCTCKMGKDP
MAVVDSQLRIHGLDGIRICDSSVMPSLIGSNTNAPTIMIAERAADLIRGNA

Sequences:

>Translated_531_residues
MTESCDYLVIGGGSAGCVMAALLSENPAARVCMIEAGGPDTNPLIHIPIGFAKMTTGPLTWGLATAPQKHANNREIPYVQ
AKVLGGGSSINAEVFTRGVPSDYDRWVEEGAEGWAFKDIQKYLIRSEGNTALSGEWHGTNGPLGVSNPTSPNPLSLAFVQ
SCQEYGIPYNPDFNGPRQEGAGFYQLTVRNSRRCSAAVGYLRPARKRANLHVITRAQVLRIAFEGKRAKGVVYAVDGQVR
EVRAEQEVIVTSGAIGTPKLLMLSGIGPAAHLQAHDVPVVHDLPGVGQNLQDHFGVDIVAELKDHESYNRYNKYHWAAWA
GLQYALFRSGPLASNVVEGGAFWYADRNARTPDLQFHFLAGAGAEAGVVSVPKGASGITLNSYTLRPKSRGTVTLRSSDP
RDNPIVDPNFLADPDDLRISAEGVKISVEMFRQPSLQKYIKSINLFDEIRPTARTYEDYTRQNGRTSYHPTCTCKMGKDP
MAVVDSQLRIHGLDGIRICDSSVMPSLIGSNTNAPTIMIAERAADLIRGNA
>Mature_530_residues
TESCDYLVIGGGSAGCVMAALLSENPAARVCMIEAGGPDTNPLIHIPIGFAKMTTGPLTWGLATAPQKHANNREIPYVQA
KVLGGGSSINAEVFTRGVPSDYDRWVEEGAEGWAFKDIQKYLIRSEGNTALSGEWHGTNGPLGVSNPTSPNPLSLAFVQS
CQEYGIPYNPDFNGPRQEGAGFYQLTVRNSRRCSAAVGYLRPARKRANLHVITRAQVLRIAFEGKRAKGVVYAVDGQVRE
VRAEQEVIVTSGAIGTPKLLMLSGIGPAAHLQAHDVPVVHDLPGVGQNLQDHFGVDIVAELKDHESYNRYNKYHWAAWAG
LQYALFRSGPLASNVVEGGAFWYADRNARTPDLQFHFLAGAGAEAGVVSVPKGASGITLNSYTLRPKSRGTVTLRSSDPR
DNPIVDPNFLADPDDLRISAEGVKISVEMFRQPSLQKYIKSINLFDEIRPTARTYEDYTRQNGRTSYHPTCTCKMGKDPM
AVVDSQLRIHGLDGIRICDSSVMPSLIGSNTNAPTIMIAERAADLIRGNA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=539, Percent_Identity=38.0333951762523, Blast_Score=363, Evalue=1e-100,
Organism=Escherichia coli, GI1786503, Length=542, Percent_Identity=36.7158671586716, Blast_Score=322, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI17532301, Length=557, Percent_Identity=35.0089766606822, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24642048, Length=568, Percent_Identity=36.0915492957746, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24642059, Length=567, Percent_Identity=36.5079365079365, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI24642055, Length=573, Percent_Identity=35.4275741710297, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24642042, Length=562, Percent_Identity=36.2989323843416, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24642039, Length=573, Percent_Identity=35.2530541012216, Blast_Score=316, Evalue=3e-86,
Organism=Drosophila melanogaster, GI45551458, Length=566, Percent_Identity=36.0424028268551, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=36.140350877193, Blast_Score=312, Evalue=4e-85,
Organism=Drosophila melanogaster, GI18859995, Length=584, Percent_Identity=33.5616438356164, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI17137792, Length=550, Percent_Identity=35.4545454545455, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24650267, Length=566, Percent_Identity=33.9222614840989, Blast_Score=278, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24642037, Length=577, Percent_Identity=33.9688041594454, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24642035, Length=574, Percent_Identity=32.5783972125435, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24642051, Length=569, Percent_Identity=30.7557117750439, Blast_Score=245, Evalue=4e-65,
Organism=Drosophila melanogaster, GI18859993, Length=571, Percent_Identity=32.2241681260946, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24645930, Length=567, Percent_Identity=27.8659611992945, Blast_Score=165, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24642057, Length=597, Percent_Identity=27.8056951423786, Blast_Score=148, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 57548; Mature: 57417

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2 ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESCDYLVIGGGSAGCVMAALLSENPAARVCMIEAGGPDTNPLIHIPIGFAKMTTGPLT
CCCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCHHHEECCCCE
WGLATAPQKHANNREIPYVQAKVLGGGSSINAEVFTRGVPSDYDRWVEEGAEGWAFKDIQ
ECCCCCCHHCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCHHHHH
KYLIRSEGNTALSGEWHGTNGPLGVSNPTSPNPLSLAFVQSCQEYGIPYNPDFNGPRQEG
HHHHHCCCCEEECCEECCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCHHHC
AGFYQLTVRNSRRCSAAVGYLRPARKRANLHVITRAQVLRIAFEGKRAKGVVYAVDGQVR
CCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHEEEEEEEECCCCCCEEEEEECCCHH
EVRAEQEVIVTSGAIGTPKLLMLSGIGPAAHLQAHDVPVVHDLPGVGQNLQDHFGVDIVA
HHCCCCEEEEECCCCCCCCEEEEECCCCHHCEECCCCCEEECCCCCCCCHHHHCCCEEEE
ELKDHESYNRYNKYHWAAWAGLQYALFRSGPLASNVVEGGAFWYADRNARTPDLQFHFLA
EECCCCCHHHCCCEEEEECCCCEEEEECCCCCHHHHHCCCEEEEECCCCCCCCEEEEEEE
GAGAEAGVVSVPKGASGITLNSYTLRPKSRGTVTLRSSDPRDNPIVDPNFLADPDDLRIS
CCCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
AEGVKISVEMFRQPSLQKYIKSINLFDEIRPTARTYEDYTRQNGRTSYHPTCTCKMGKDP
ECCEEEEEHHHCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
MAVVDSQLRIHGLDGIRICDSSVMPSLIGSNTNAPTIMIAERAADLIRGNA
HHHCCCCEEEECCCCEEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHCCCC
>Mature Secondary Structure 
TESCDYLVIGGGSAGCVMAALLSENPAARVCMIEAGGPDTNPLIHIPIGFAKMTTGPLT
CCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCHHHEECCCCE
WGLATAPQKHANNREIPYVQAKVLGGGSSINAEVFTRGVPSDYDRWVEEGAEGWAFKDIQ
ECCCCCCHHCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCHHHHH
KYLIRSEGNTALSGEWHGTNGPLGVSNPTSPNPLSLAFVQSCQEYGIPYNPDFNGPRQEG
HHHHHCCCCEEECCEECCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCHHHC
AGFYQLTVRNSRRCSAAVGYLRPARKRANLHVITRAQVLRIAFEGKRAKGVVYAVDGQVR
CCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHEEEEEEEECCCCCCEEEEEECCCHH
EVRAEQEVIVTSGAIGTPKLLMLSGIGPAAHLQAHDVPVVHDLPGVGQNLQDHFGVDIVA
HHCCCCEEEEECCCCCCCCEEEEECCCCHHCEECCCCCEEECCCCCCCCHHHHCCCEEEE
ELKDHESYNRYNKYHWAAWAGLQYALFRSGPLASNVVEGGAFWYADRNARTPDLQFHFLA
EECCCCCHHHCCCEEEEECCCCEEEEECCCCCHHHHHCCCEEEEECCCCCCCCEEEEEEE
GAGAEAGVVSVPKGASGITLNSYTLRPKSRGTVTLRSSDPRDNPIVDPNFLADPDDLRIS
CCCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEE
AEGVKISVEMFRQPSLQKYIKSINLFDEIRPTARTYEDYTRQNGRTSYHPTCTCKMGKDP
ECCEEEEEHHHCCCCHHHHHHHCCHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
MAVVDSQLRIHGLDGIRICDSSVMPSLIGSNTNAPTIMIAERAADLIRGNA
HHHCCCCEEEECCCCEEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]