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The map label for this gene is pdxA [H]

Identifier: 162147128

GI number: 162147128

Start: 1330421

End: 1331413

Strand: Direct

Name: pdxA [H]

Synonym: GDI_1333

Alternate gene names: 162147128

Gene position: 1330421-1331413 (Clockwise)

Preceding gene: 162147127

Following gene: 162147129

Centisome position: 33.73

GC content: 73.51

Gene sequence:

>993_bases
ATGGAAGGCGGGGCGCGGACGCTGCTGGCCCTGACGATGGGCGATCCGGCCGGGATCGGGCCGGAAATCACCACTGCCGC
CTGGCGCGCCCTGCGCGCGGGCGGCGGGCCGGCCTTCGTCGTGCCCGGTGATGCCGCCCTGCTGGCGGCCCATGCCCCGG
TCCGGATCGTGGCGGACGTGGCGCAGGCGGCGGCGGCCTTCACCGATGCGATCCCGGTGCTGGCGGTCGATCTGCCCGGT
CCGGTGCAGCCGGGGCGGCCGGACCCCGCCAACGCGCCCGCCATCACCGGCAGCATCGACTGCGCCGTGGCGCTGGCGCT
GGCCGGGCAGGTGGGCGGCGTCGTCACCAATCCGATCAGCAAGCTGGTGCTGAAGCGGGCCGGCTTCCGCCATCCGGGCC
ATACCGAATACCTGGCCGAACTCTGCGCCGTGCCGGGGCAGGAGGTCATGATGCTGGCCTGCCCCGAATTGCGGGTGGTG
CCGGTGACCATCCACATGGCGCTGCGCCGGGCGCTGGACAGCCTGACGACGGCGGAAATCGTGCGCTGCGGCCGCACCGC
CGCCGCTGCCCTGCGCCGCGATTTCGGGATCGCGGCGCCGCGCGTGGCCGTCGCCGGCCTGAACCCGCATGCCGGCGAGG
GCGGGGTGATGGGGGACGAGGAACGGACGATCATCGCCCCCGCGCTGGACGCATTGCGCGCCGACGGGATCGCGGTCAGC
GGCCCCTGGCCGCCGGATACGATGTTCACCCCCCTGGTCCGCGCCCGATACGATGTGGCGCTGTGCATGTATCACGACCA
GGCGCTGATCCCGCTGAAGACGATCGACATGGCGGGCGGGGTCAACGTCACGCTGGGCCTGCCCATCATCCGCACCTCGC
CCGACCACGGCACCGCCTTCGACATCGCGGGACAGGGCCTGGCCGACCCGTCCAGCCTGCTGGCCGCCCTGCGCCTGGCC
GACGAAATGACCCGCAACCGGAGGGCCGCATGA

Upstream 100 bases:

>100_bases
TCGTTCCATCGCGGCATCCGCTCCTGGGTGCGGGTGCTGGACGCGCTGGCCCATGATGGGGCCCCTGACGGGACCCGCGA
CATGGCAGGCGCGGCCTGAC

Downstream 100 bases:

>100_bases
CGGATTCCCGTACCCAGGCCCTGCGCCTGGGCGTCAATATCGACCACGTCGCCACCGTGCGGAACGCGCGCGGCGGCGCC
CACCCGGACCCGGTCGCCGC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MEGGARTLLALTMGDPAGIGPEITTAAWRALRAGGGPAFVVPGDAALLAAHAPVRIVADVAQAAAAFTDAIPVLAVDLPG
PVQPGRPDPANAPAITGSIDCAVALALAGQVGGVVTNPISKLVLKRAGFRHPGHTEYLAELCAVPGQEVMMLACPELRVV
PVTIHMALRRALDSLTTAEIVRCGRTAAAALRRDFGIAAPRVAVAGLNPHAGEGGVMGDEERTIIAPALDALRADGIAVS
GPWPPDTMFTPLVRARYDVALCMYHDQALIPLKTIDMAGGVNVTLGLPIIRTSPDHGTAFDIAGQGLADPSSLLAALRLA
DEMTRNRRAA

Sequences:

>Translated_330_residues
MEGGARTLLALTMGDPAGIGPEITTAAWRALRAGGGPAFVVPGDAALLAAHAPVRIVADVAQAAAAFTDAIPVLAVDLPG
PVQPGRPDPANAPAITGSIDCAVALALAGQVGGVVTNPISKLVLKRAGFRHPGHTEYLAELCAVPGQEVMMLACPELRVV
PVTIHMALRRALDSLTTAEIVRCGRTAAAALRRDFGIAAPRVAVAGLNPHAGEGGVMGDEERTIIAPALDALRADGIAVS
GPWPPDTMFTPLVRARYDVALCMYHDQALIPLKTIDMAGGVNVTLGLPIIRTSPDHGTAFDIAGQGLADPSSLLAALRLA
DEMTRNRRAA
>Mature_330_residues
MEGGARTLLALTMGDPAGIGPEITTAAWRALRAGGGPAFVVPGDAALLAAHAPVRIVADVAQAAAAFTDAIPVLAVDLPG
PVQPGRPDPANAPAITGSIDCAVALALAGQVGGVVTNPISKLVLKRAGFRHPGHTEYLAELCAVPGQEVMMLACPELRVV
PVTIHMALRRALDSLTTAEIVRCGRTAAAALRRDFGIAAPRVAVAGLNPHAGEGGVMGDEERTIIAPALDALRADGIAVS
GPWPPDTMFTPLVRARYDVALCMYHDQALIPLKTIDMAGGVNVTLGLPIIRTSPDHGTAFDIAGQGLADPSSLLAALRLA
DEMTRNRRAA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=324, Percent_Identity=39.5061728395062, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 33876; Mature: 33876

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGGARTLLALTMGDPAGIGPEITTAAWRALRAGGGPAFVVPGDAALLAAHAPVRIVADV
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHH
AQAAAAFTDAIPVLAVDLPGPVQPGRPDPANAPAITGSIDCAVALALAGQVGGVVTNPIS
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHH
KLVLKRAGFRHPGHTEYLAELCAVPGQEVMMLACPELRVVPVTIHMALRRALDSLTTAEI
HHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
VRCGRTAAAALRRDFGIAAPRVAVAGLNPHAGEGGVMGDEERTIIAPALDALRADGIAVS
HHHCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEC
GPWPPDTMFTPLVRARYDVALCMYHDQALIPLKTIDMAGGVNVTLGLPIIRTSPDHGTAF
CCCCCCHHHHHHHHHHHCEEEEEECCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCEE
DIAGQGLADPSSLLAALRLADEMTRNRRAA
EECCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEGGARTLLALTMGDPAGIGPEITTAAWRALRAGGGPAFVVPGDAALLAAHAPVRIVADV
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHH
AQAAAAFTDAIPVLAVDLPGPVQPGRPDPANAPAITGSIDCAVALALAGQVGGVVTNPIS
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCHHHHHH
KLVLKRAGFRHPGHTEYLAELCAVPGQEVMMLACPELRVVPVTIHMALRRALDSLTTAEI
HHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHH
VRCGRTAAAALRRDFGIAAPRVAVAGLNPHAGEGGVMGDEERTIIAPALDALRADGIAVS
HHHCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEC
GPWPPDTMFTPLVRARYDVALCMYHDQALIPLKTIDMAGGVNVTLGLPIIRTSPDHGTAF
CCCCCCHHHHHHHHHHHCEEEEEECCCCCCEEEEEECCCCCEEEECCEEEEECCCCCCEE
DIAGQGLADPSSLLAALRLADEMTRNRRAA
EECCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA