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The map label for this gene is pyrF [H]

Identifier: 162147124

GI number: 162147124

Start: 1327335

End: 1328042

Strand: Reverse

Name: pyrF [H]

Synonym: GDI_1329

Alternate gene names: 162147124

Gene position: 1328042-1327335 (Counterclockwise)

Preceding gene: 162147125

Following gene: 162147123

Centisome position: 33.67

GC content: 74.72

Gene sequence:

>708_bases
ATGACCGCGCGCCGCACGCGCCTGATCGTGGCGCTGGACACCAAGGACACCGCGCAGGCCGCACGCTGGCGCGACCAGAC
CGCCGCCAGCGCCGATGCGGTGAAGCTGGGGCTGGAATTCACTTACGCGTGCGGGCTGGACGCGGTGCGGCAGGTCGCGG
GTCCGCGCAGCCTGTTCCTGGACCTGAAGCTGCACGACATTCCCAACACCGTGGCCTCGGCCATCGGCAGCCTGGCGGCG
ACGCGCCCGGCGATGCTGACGATCCATGCCATGGGGGGTGCCGCGATGATCGCGGCGGCGCGCCAGGCCGTGGACCGGGC
CTTCCCGCCCGAGGCGCGGCCGCTGCTGCTGGCGGTCACGGTGCTGACCAGCATGGACGCGGATGCGCTGCATGGGATCG
GCATCGCCGACGATCCATGCCGGCAGGTGCTGCGGCTGGGCGCGCTGGCCATGGAATCGGGGGCGGACGGGCTGGTCTGC
TCGCCGCGTGAAATCGCCCCGTTGCGCGACCGGCTGGGCGGGCGGGCGGTGCTGGTCGTGCCCGGCATCCGCCCCGAGGG
CGCGGCGATGGGCGACCAGAAGCGGGTGATGACCCCGGCCGAGGCCAGCCGCGCCGGCGCCGACTGGATCGTGGTCGGGC
GACCGATCACCACCGCCGCCGACCCGGCAGCCGCTGCCGCCGCCGTGGCGGCCGAACTGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGCAGGCCGAGACCCTGATCCCGCCGGCGGCGCCCGCCTCCGGCCCGGTCGGGCTGGAACCCGCCGCGCCGGCCCCGGTG
CAGCGCGACGTGCCGCTGTC

Downstream 100 bases:

>100_bases
CCGCGCCATGCCCCCCCCCGCCGACACGCGGATCGGCGTCAAGATCTGTGGCCTGACCGAGCCCGCCGGGCTGGAGGCCG
CCGTCACGCACGGGGCCGAC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTARRTRLIVALDTKDTAQAARWRDQTAASADAVKLGLEFTYACGLDAVRQVAGPRSLFLDLKLHDIPNTVASAIGSLAA
TRPAMLTIHAMGGAAMIAAARQAVDRAFPPEARPLLLAVTVLTSMDADALHGIGIADDPCRQVLRLGALAMESGADGLVC
SPREIAPLRDRLGGRAVLVVPGIRPEGAAMGDQKRVMTPAEASRAGADWIVVGRPITTAADPAAAAAAVAAELAG

Sequences:

>Translated_235_residues
MTARRTRLIVALDTKDTAQAARWRDQTAASADAVKLGLEFTYACGLDAVRQVAGPRSLFLDLKLHDIPNTVASAIGSLAA
TRPAMLTIHAMGGAAMIAAARQAVDRAFPPEARPLLLAVTVLTSMDADALHGIGIADDPCRQVLRLGALAMESGADGLVC
SPREIAPLRDRLGGRAVLVVPGIRPEGAAMGDQKRVMTPAEASRAGADWIVVGRPITTAADPAAAAAAVAAELAG
>Mature_234_residues
TARRTRLIVALDTKDTAQAARWRDQTAASADAVKLGLEFTYACGLDAVRQVAGPRSLFLDLKLHDIPNTVASAIGSLAAT
RPAMLTIHAMGGAAMIAAARQAVDRAFPPEARPLLLAVTVLTSMDADALHGIGIADDPCRQVLRLGALAMESGADGLVCS
PREIAPLRDRLGGRAVLVVPGIRPEGAAMGDQKRVMTPAEASRAGADWIVVGRPITTAADPAAAAAAVAAELAG

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=227, Percent_Identity=42.2907488986784, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 24199; Mature: 24068

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARRTRLIVALDTKDTAQAARWRDQTAASADAVKLGLEFTYACGLDAVRQVAGPRSLFL
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEECEEEEEHHCHHHHHHHCCCCCEEE
DLKLHDIPNTVASAIGSLAATRPAMLTIHAMGGAAMIAAARQAVDRAFPPEARPLLLAVT
EEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
VLTSMDADALHGIGIADDPCRQVLRLGALAMESGADGLVCSPREIAPLRDRLGGRAVLVV
HHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCEEEEEE
PGIRPEGAAMGDQKRVMTPAEASRAGADWIVVGRPITTAADPAAAAAAVAAELAG
CCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARRTRLIVALDTKDTAQAARWRDQTAASADAVKLGLEFTYACGLDAVRQVAGPRSLFL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEECEEEEEHHCHHHHHHHCCCCCEEE
DLKLHDIPNTVASAIGSLAATRPAMLTIHAMGGAAMIAAARQAVDRAFPPEARPLLLAVT
EEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
VLTSMDADALHGIGIADDPCRQVLRLGALAMESGADGLVCSPREIAPLRDRLGGRAVLVV
HHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHCCCCEEEEEE
PGIRPEGAAMGDQKRVMTPAEASRAGADWIVVGRPITTAADPAAAAAAVAAELAG
CCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA