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The map label for this gene is etfA [H]

Identifier: 162147075

GI number: 162147075

Start: 1277573

End: 1278508

Strand: Direct

Name: etfA [H]

Synonym: GDI_1280

Alternate gene names: 162147075

Gene position: 1277573-1278508 (Clockwise)

Preceding gene: 162147074

Following gene: 162147079

Centisome position: 32.39

GC content: 68.8

Gene sequence:

>936_bases
ATGACCGTACTCGTTTTCCTGGACCATGAGTCCGGCACGATCCGCCAGGCTTCGCGTTCCGCGGTGACGGCGGCCCTGGA
ACTGGGCAAGTCGGCGGGGGACGTCCATGCCCTGGTGACGGGTGACGCGGCGGTGGCGGACGCGGCGGCGAAAATTCCCG
GTATCGCCAAGGTTTTGCGCGCCGCCGGGGCCGCCGTGGCCCACGAACTGGCCGAACCGCTGGCCGCGCTGATCGCCGAC
CTCGCCCCGTCCTACAGCCACATCGTCGCGGCGGCGGGTGCGACCGGCAAGAACGTGCTGCCGCGCGCGGCGGCCCTGCT
GGACGTGCAGCCGATTCCCGACGTGGTGTCGATCATCGATGCCGAGACCTTCGTGCGCCCGATCTATGCGGGCAGCGCCC
TGGCGACGGTGAAGTCGGCCGACGCGTACAAGGTGGTGACGGTGCGCGCCTCGTCCTTCGACCCCGCGCCGGCCGAGGGC
GGCAGCGCCGTGGTGGAACAGGTCACGGTGCCGGACGGGTCCGCCCTGTCGGAATTCGTGTCGATCGAACTGTCGAAATC
CGAACGCCCGGAACTGGAATCCGCACGGGTCATCGTCTCCGGCGGGCGCGGCCTGCAGAACCAGGAGAATTTCAAGCTCC
TCGACCCGCTGGCCGATCGGCTGGGGGCTGCGATCGGCGCCTCGCGCGCGGCGGTGGATGCGGGCTTCGTGCCCAACGAC
TACCAGGTGGGGCAGACCGGCAAGATCGTGGCGCCGGACCTGTATATCGCCATCGGCATCTCGGGCGCGATCCAGCATCT
GGCCGGCATGAAGGACAGCAAGGTCATCGTGGCGATCAACAAGGACCCCGAGGCCCCGATCTTCCAGGTCGCGGATTACG
GGCTGGTCGCGGATCTGTTCGAGGTGCTGCCGCAGCTTGAGGCCGCGCTGGGTTAA

Upstream 100 bases:

>100_bases
TCTCGGTGGCCGAACCCCCGGCGCGCAAGGCCGGCGTCAAGGTCGCGTCCGCCGAGGATCTGGTGGCGCGTCTGCGCAAT
GAAGCGAAGGTGATCTGATC

Downstream 100 bases:

>100_bases
GACCCTTACTCTCCCAGCCGTGCCCGCGCCCGGCTGACGACGGTTTCGTACTCCTCGGGGCTCAGATGCCCCTCATGCAG
CATCGCGCTGGCCCGGGCCA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTVLVFLDHESGTIRQASRSAVTAALELGKSAGDVHALVTGDAAVADAAAKIPGIAKVLRAAGAAVAHELAEPLAALIAD
LAPSYSHIVAAAGATGKNVLPRAAALLDVQPIPDVVSIIDAETFVRPIYAGSALATVKSADAYKVVTVRASSFDPAPAEG
GSAVVEQVTVPDGSALSEFVSIELSKSERPELESARVIVSGGRGLQNQENFKLLDPLADRLGAAIGASRAAVDAGFVPND
YQVGQTGKIVAPDLYIAIGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVADLFEVLPQLEAALG

Sequences:

>Translated_311_residues
MTVLVFLDHESGTIRQASRSAVTAALELGKSAGDVHALVTGDAAVADAAAKIPGIAKVLRAAGAAVAHELAEPLAALIAD
LAPSYSHIVAAAGATGKNVLPRAAALLDVQPIPDVVSIIDAETFVRPIYAGSALATVKSADAYKVVTVRASSFDPAPAEG
GSAVVEQVTVPDGSALSEFVSIELSKSERPELESARVIVSGGRGLQNQENFKLLDPLADRLGAAIGASRAAVDAGFVPND
YQVGQTGKIVAPDLYIAIGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVADLFEVLPQLEAALG
>Mature_310_residues
TVLVFLDHESGTIRQASRSAVTAALELGKSAGDVHALVTGDAAVADAAAKIPGIAKVLRAAGAAVAHELAEPLAALIADL
APSYSHIVAAAGATGKNVLPRAAALLDVQPIPDVVSIIDAETFVRPIYAGSALATVKSADAYKVVTVRASSFDPAPAEGG
SAVVEQVTVPDGSALSEFVSIELSKSERPELESARVIVSGGRGLQNQENFKLLDPLADRLGAAIGASRAAVDAGFVPNDY
QVGQTGKIVAPDLYIAIGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVADLFEVLPQLEAALG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=313, Percent_Identity=56.5495207667732, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=61.3382899628253, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1786226, Length=212, Percent_Identity=35.377358490566, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787990, Length=246, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI87082157, Length=256, Percent_Identity=30.078125, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=54.7770700636943, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6325261, Length=321, Percent_Identity=47.0404984423676, Blast_Score=261, Evalue=8e-71,
Organism=Drosophila melanogaster, GI17136898, Length=314, Percent_Identity=57.6433121019108, Blast_Score=334, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652801, Length=314, Percent_Identity=57.6433121019108, Blast_Score=334, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31711; Mature: 31580

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVFLDHESGTIRQASRSAVTAALELGKSAGDVHALVTGDAAVADAAAKIPGIAKVLR
CEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
AAGAAVAHELAEPLAALIADLAPSYSHIVAAAGATGKNVLPRAAALLDVQPIPDVVSIID
HHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
AETFVRPIYAGSALATVKSADAYKVVTVRASSFDPAPAEGGSAVVEQVTVPDGSALSEFV
HHHHHHHHHCCCHHHEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHH
SIELSKSERPELESARVIVSGGRGLQNQENFKLLDPLADRLGAAIGASRAAVDAGFVPND
EEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPDLYIAIGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVADLF
CEECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHCCHHHHHHH
EVLPQLEAALG
HHHHHHHHHCC
>Mature Secondary Structure 
TVLVFLDHESGTIRQASRSAVTAALELGKSAGDVHALVTGDAAVADAAAKIPGIAKVLR
EEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHCCHHHHHHH
AAGAAVAHELAEPLAALIADLAPSYSHIVAAAGATGKNVLPRAAALLDVQPIPDVVSIID
HHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHH
AETFVRPIYAGSALATVKSADAYKVVTVRASSFDPAPAEGGSAVVEQVTVPDGSALSEFV
HHHHHHHHHCCCHHHEEECCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHH
SIELSKSERPELESARVIVSGGRGLQNQENFKLLDPLADRLGAAIGASRAAVDAGFVPND
EEEECCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPDLYIAIGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVADLF
CEECCCCCEECCCEEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCEEHHHCCHHHHHHH
EVLPQLEAALG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]