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The map label for this gene is etfD [H]

Identifier: 162147073

GI number: 162147073

Start: 1275106

End: 1276743

Strand: Direct

Name: etfD [H]

Synonym: GDI_1278

Alternate gene names: 162147073

Gene position: 1275106-1276743 (Clockwise)

Preceding gene: 162147072

Following gene: 162147074

Centisome position: 32.33

GC content: 67.95

Gene sequence:

>1638_bases
ATGACCGAACACGCCCGCGAGACGATGGAATTCGATATTGTTATTGTCGGCGGCGGTCCGTCCGGTCTGGCCGCGGCGAT
CCGGCTGCGCCAGCTGGTCCCCGACGCCACGGTCTGCCTGATCGAGAAGGGCAGTGAAATCGGCGCCCATATCCTGTCGG
GCGCGGTGATCGAACCCCGCGCGCTGGACGAGCTGCTGCCCGACTGGCGCGAGACCGGCGCCCCGCTGCACACCCCCGTG
TCCGAGGAAGCGATGCTCTTCCTGACGGAAAAGCGCGGCTATGCGGTGCCGATGCTGGACCGGCTGATGCCGCACATGCG
CAATCACGGCAACTACATCGTCAGCCTGGGCGACGTCTGCCGCTGGCTGGCCGCGCGGGCCGAGGAACTGGGCGTCGAGA
TCTATCCCGGTTTCGCCGGCGCCGAGCTGCTGGTCGAGGACGGGCGCGTGGTGGGCGTCGCGACCGGCGACATGGGCGTG
GGCCGCGACGGCCAGCCCGGCGCGAACTTCGCCCCCGGCATGGAACTGCGCGCCCGCTACACCCTGTTCGCCGAAGGCTG
CCGCGGGTCGCTGACCAAACGGCTGATGGCGACCTACGACCTGCGCAAGGGCGTGGACCCCCAGACCTACGGCCTGGGCA
TCAAGGAATTGTGGGAAATCCCCAAGGAACGGCACCGCCCCGGCCTGGTGCAGCATTCCTTCGGCTGGCCGCTGGACGAC
CGCACCTATGGCGGCGCCTGGATGTATCATTTCGGCGAGAACCTGGTGTCCTACGGCTTCGTCGTCGGGCTGGACTACGC
CAATACCTGGCTGTCGCCGTTCGACGAGATGCAGCGGCTGAAGCTGCATCCGTCCTTCCGGCCGTATTTCGAGGGGGGAC
GGCGCATCGCCTATGGCGCCCGCGCCCTGTCCGAAGGCGGCATCCAGTCCCTGCCGCGCCTGACCTTCCCCGGTGGCGCG
CTGATCGGCGACACGGCGGGCTTCCTGAACGTGCCGAAGATCAAGGGCACCCATACGGCCATGAAATCCGGCATGCTGGC
GGCCGAGGCGGTGGCCGAGGCCATGCAGGCCGGCACGGCCGAACCCACGTCCTACATGCGCCGGGTGCGCGCGTCGTGGC
TGTGGGAGGAACTGCGCGGCGTGCGCAATATCCGCCCCGCCTTCGCGCGGTTCGGGATGAAGGGCGGGGCGCTCTATTCC
GGGATCGACGCCATGCTGCTGCGCGGTCGTGCGCCCTGGACCCTGCATCACCGCCATGCGGATAACGAGGACCTGCTGGC
CGCCGGCAAGTCCGCGCCCATCGCCTATCCCAAGCCGGACGGCAAGGTCACGTTCGACCGGCTGTCGTCGGTCTTCCTGT
CCGCCACGAATCACGAGGAAGACCAGCCGGTCCACCTGAAGCTGCGCAATCCCGCGATCTGGAAGACCGTGAACTGGGAC
GTGTTCCGCGCGCCCGAAAGCCGCTACTGCCCGGCCGGGGTGTATGAAGTCGTGGATGCGGACACCGATCCGCGCCTGCA
GATCAACGCGCAGAACTGCGTCCATTGCAAGACGTGCGATATCAAGGACCCCACCCAGAACATCGACTGGGTCACGCCCG
AAGGCGCGGGCGGCCCGAATTACCCCGGCGGGATGTGA

Upstream 100 bases:

>100_bases
TCTAGTGTCCCCGATCGAAATTCTTCATGAGGAAAGCATCCAAGACTTTCCACCCATGCCGTGACCCCCTCATGGCGCAG
CAGGACGAGACGAAAGAGGC

Downstream 100 bases:

>100_bases
TTTCCCCGCGAAATACGGTATGGGGGGCGTCCTGAACGGGCGCCCCGTTCCCCGTAGACAGACAGGCGAAGATGTCCATG
AAGGTTCTTGTTCCCGTAAA

Product: electron transfer flavoprotein-ubiquinone oxidoreductase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTEHARETMEFDIVIVGGGPSGLAAAIRLRQLVPDATVCLIEKGSEIGAHILSGAVIEPRALDELLPDWRETGAPLHTPV
SEEAMLFLTEKRGYAVPMLDRLMPHMRNHGNYIVSLGDVCRWLAARAEELGVEIYPGFAGAELLVEDGRVVGVATGDMGV
GRDGQPGANFAPGMELRARYTLFAEGCRGSLTKRLMATYDLRKGVDPQTYGLGIKELWEIPKERHRPGLVQHSFGWPLDD
RTYGGAWMYHFGENLVSYGFVVGLDYANTWLSPFDEMQRLKLHPSFRPYFEGGRRIAYGARALSEGGIQSLPRLTFPGGA
LIGDTAGFLNVPKIKGTHTAMKSGMLAAEAVAEAMQAGTAEPTSYMRRVRASWLWEELRGVRNIRPAFARFGMKGGALYS
GIDAMLLRGRAPWTLHHRHADNEDLLAAGKSAPIAYPKPDGKVTFDRLSSVFLSATNHEEDQPVHLKLRNPAIWKTVNWD
VFRAPESRYCPAGVYEVVDADTDPRLQINAQNCVHCKTCDIKDPTQNIDWVTPEGAGGPNYPGGM

Sequences:

>Translated_545_residues
MTEHARETMEFDIVIVGGGPSGLAAAIRLRQLVPDATVCLIEKGSEIGAHILSGAVIEPRALDELLPDWRETGAPLHTPV
SEEAMLFLTEKRGYAVPMLDRLMPHMRNHGNYIVSLGDVCRWLAARAEELGVEIYPGFAGAELLVEDGRVVGVATGDMGV
GRDGQPGANFAPGMELRARYTLFAEGCRGSLTKRLMATYDLRKGVDPQTYGLGIKELWEIPKERHRPGLVQHSFGWPLDD
RTYGGAWMYHFGENLVSYGFVVGLDYANTWLSPFDEMQRLKLHPSFRPYFEGGRRIAYGARALSEGGIQSLPRLTFPGGA
LIGDTAGFLNVPKIKGTHTAMKSGMLAAEAVAEAMQAGTAEPTSYMRRVRASWLWEELRGVRNIRPAFARFGMKGGALYS
GIDAMLLRGRAPWTLHHRHADNEDLLAAGKSAPIAYPKPDGKVTFDRLSSVFLSATNHEEDQPVHLKLRNPAIWKTVNWD
VFRAPESRYCPAGVYEVVDADTDPRLQINAQNCVHCKTCDIKDPTQNIDWVTPEGAGGPNYPGGM
>Mature_544_residues
TEHARETMEFDIVIVGGGPSGLAAAIRLRQLVPDATVCLIEKGSEIGAHILSGAVIEPRALDELLPDWRETGAPLHTPVS
EEAMLFLTEKRGYAVPMLDRLMPHMRNHGNYIVSLGDVCRWLAARAEELGVEIYPGFAGAELLVEDGRVVGVATGDMGVG
RDGQPGANFAPGMELRARYTLFAEGCRGSLTKRLMATYDLRKGVDPQTYGLGIKELWEIPKERHRPGLVQHSFGWPLDDR
TYGGAWMYHFGENLVSYGFVVGLDYANTWLSPFDEMQRLKLHPSFRPYFEGGRRIAYGARALSEGGIQSLPRLTFPGGAL
IGDTAGFLNVPKIKGTHTAMKSGMLAAEAVAEAMQAGTAEPTSYMRRVRASWLWEELRGVRNIRPAFARFGMKGGALYSG
IDAMLLRGRAPWTLHHRHADNEDLLAAGKSAPIAYPKPDGKVTFDRLSSVFLSATNHEEDQPVHLKLRNPAIWKTVNWDV
FRAPESRYCPAGVYEVVDADTDPRLQINAQNCVHCKTCDIKDPTQNIDWVTPEGAGGPNYPGGM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=555, Percent_Identity=56.7567567567568, Blast_Score=623, Evalue=1e-178,
Organism=Escherichia coli, GI1786227, Length=385, Percent_Identity=28.5714285714286, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787991, Length=388, Percent_Identity=27.319587628866, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082155, Length=371, Percent_Identity=29.1105121293801, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25144720, Length=556, Percent_Identity=55.2158273381295, Blast_Score=612, Evalue=1e-175,
Organism=Saccharomyces cerevisiae, GI6324932, Length=586, Percent_Identity=46.4163822525597, Blast_Score=516, Evalue=1e-147,
Organism=Drosophila melanogaster, GI24652256, Length=554, Percent_Identity=54.6931407942238, Blast_Score=612, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 59953; Mature: 59822

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHARETMEFDIVIVGGGPSGLAAAIRLRQLVPDATVCLIEKGSEIGAHILSGAVIEPR
CCCHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCH
ALDELLPDWRETGAPLHTPVSEEAMLFLTEKRGYAVPMLDRLMPHMRNHGNYIVSLGDVC
HHHHHCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEHHHHH
RWLAARAEELGVEIYPGFAGAELLVEDGRVVGVATGDMGVGRDGQPGANFAPGMELRARY
HHHHHHHHHCCEEEECCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEE
TLFAEGCRGSLTKRLMATYDLRKGVDPQTYGLGIKELWEIPKERHRPGLVQHSFGWPLDD
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHCCHHHCCCCCEECCCCCCCCC
RTYGGAWMYHFGENLVSYGFVVGLDYANTWLSPFDEMQRLKLHPSFRPYFEGGRRIAYGA
CCCCCEEHHHHHHHHHHCCEEEEECHHHHHCCCHHHHHHHHCCCCCCHHHCCCCEEEEHH
RALSEGGIQSLPRLTFPGGALIGDTAGFLNVPKIKGTHTAMKSGMLAAEAVAEAMQAGTA
HHHHCCCHHHCCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
EPTSYMRRVRASWLWEELRGVRNIRPAFARFGMKGGALYSGIDAMLLRGRAPWTLHHRHA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
DNEDLLAAGKSAPIAYPKPDGKVTFDRLSSVFLSATNHEEDQPVHLKLRNPAIWKTVNWD
CCCHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCE
VFRAPESRYCPAGVYEVVDADTDPRLQINAQNCVHCKTCDIKDPTQNIDWVTPEGAGGPN
EEECCCCCCCCCCHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCCEECCCCCCCCC
YPGGM
CCCCC
>Mature Secondary Structure 
TEHARETMEFDIVIVGGGPSGLAAAIRLRQLVPDATVCLIEKGSEIGAHILSGAVIEPR
CCHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCH
ALDELLPDWRETGAPLHTPVSEEAMLFLTEKRGYAVPMLDRLMPHMRNHGNYIVSLGDVC
HHHHHCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEHHHHH
RWLAARAEELGVEIYPGFAGAELLVEDGRVVGVATGDMGVGRDGQPGANFAPGMELRARY
HHHHHHHHHCCEEEECCCCCCEEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEE
TLFAEGCRGSLTKRLMATYDLRKGVDPQTYGLGIKELWEIPKERHRPGLVQHSFGWPLDD
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHCCHHHCCCCCEECCCCCCCCC
RTYGGAWMYHFGENLVSYGFVVGLDYANTWLSPFDEMQRLKLHPSFRPYFEGGRRIAYGA
CCCCCEEHHHHHHHHHHCCEEEEECHHHHHCCCHHHHHHHHCCCCCCHHHCCCCEEEEHH
RALSEGGIQSLPRLTFPGGALIGDTAGFLNVPKIKGTHTAMKSGMLAAEAVAEAMQAGTA
HHHHCCCHHHCCCEECCCCCEEECCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
EPTSYMRRVRASWLWEELRGVRNIRPAFARFGMKGGALYSGIDAMLLRGRAPWTLHHRHA
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCC
DNEDLLAAGKSAPIAYPKPDGKVTFDRLSSVFLSATNHEEDQPVHLKLRNPAIWKTVNWD
CCCHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCE
VFRAPESRYCPAGVYEVVDADTDPRLQINAQNCVHCKTCDIKDPTQNIDWVTPEGAGGPN
EEECCCCCCCCCCHHHHHCCCCCCCEEECCCCCEEEEECCCCCCCCCCCEECCCCCCCCC
YPGGM
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9294455 [H]