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The map label for this gene is qor [H]

Identifier: 162147026

GI number: 162147026

Start: 1223660

End: 1224631

Strand: Direct

Name: qor [H]

Synonym: GDI_1231

Alternate gene names: 162147026

Gene position: 1223660-1224631 (Clockwise)

Preceding gene: 162147025

Following gene: 162147029

Centisome position: 31.02

GC content: 68.42

Gene sequence:

>972_bases
ATGTACAGGGCGATTCGCATCCATGATTACGGCGGGCCCGAAGTCCTGAAGCTGGAAACGCTGCCCAGCCCCGTGCCCGG
ACGGGGGGAAATCCTGATCCGGCAGGAGGCGATCGGCGTCAATTTCATCGACATCTATTTTCGCACCGGGCTGTACAAGC
TGCCCACCCTGCCCGCCATCCCGGGGATGGAAGGGGCCGGAACCGTGCTCGCCGTGGGCGAGGACGTGGCCGACCTGGTT
CCCGGCGACCGGGTGGCCTATCCCACCGCCCTGGGCGGCTATGCCGAATGCCGCACCATCGCGGCCGATCGCGTCGTGCC
CCTGCCGCCCGACATTTCGTCCGAAGTCGCGGCCGCCTGCATGCTGCGCGGCCTGACGGTGCATATGCTGCTGCGCGAGG
TCCATGCGGTACAACCGGGCGAGACGATCCTGGTCCATGCGGCGGCGGGCGGTGTCGGCCTGCTGATGTGCCAGTGGGCG
CGGTATCTGGGCGTGCGGATGATCGGCGTGGTGTCGACCGAGGAAAAGGGCGAACTGGCCCGGCAGAACGGGGCGTCCGA
CATCCTGGTCGGGTACGACAACCTGGCCGCGCGCGTGCGCAAGCTGACGGATGGCGCCATGGTGCCCGTCGTCTATGACA
GTATCGGCAAGGACACGTTCGTCGCCAGCCTGGATTGCCTGGCACCGCGCGGACTGATGGTCAGCTACGGCAACGCGTCG
GGCGAGATCACGGGCATTTCGGTGGGCATGCTGGCCACGCGCGGCAGCCTGTATCTGACCCGGCCGGGGCTGACGACCTA
TATCGCCCAGCGTCCGGCGCTGCTGGCAGGCGCCGCGGAACTGTTCGGGCTGATCGCGCAGGGTGTGCTTTCGGTGCGGA
TCGGCCAGCGCTTCGCCCTGGCCGACGCGGCGGAAGCCCAGCGGGCGCTGGAGGCGCGGACGACGGTAGGGAGTACGATC
CTGGTGCCGTGA

Upstream 100 bases:

>100_bases
TTGACCGACAAGCTCTATCTTCTGGGCCTGGAACGCGCCCCCATTCCAGCCCACGCGCACGAGACGGCCTGACACAGCCA
CCACGGAAAGGAAGAGAGCG

Downstream 100 bases:

>100_bases
TAGATATGGGGCTCTGCCCCATGCCCCGCCAAAGGCCGGGGGCCTTTGGAAACCGATTCCGGCTTCCCTACGACAGCGCC
ACCCCGGTCAGCCGCTCGGA

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MYRAIRIHDYGGPEVLKLETLPSPVPGRGEILIRQEAIGVNFIDIYFRTGLYKLPTLPAIPGMEGAGTVLAVGEDVADLV
PGDRVAYPTALGGYAECRTIAADRVVPLPPDISSEVAAACMLRGLTVHMLLREVHAVQPGETILVHAAAGGVGLLMCQWA
RYLGVRMIGVVSTEEKGELARQNGASDILVGYDNLAARVRKLTDGAMVPVVYDSIGKDTFVASLDCLAPRGLMVSYGNAS
GEITGISVGMLATRGSLYLTRPGLTTYIAQRPALLAGAAELFGLIAQGVLSVRIGQRFALADAAEAQRALEARTTVGSTI
LVP

Sequences:

>Translated_323_residues
MYRAIRIHDYGGPEVLKLETLPSPVPGRGEILIRQEAIGVNFIDIYFRTGLYKLPTLPAIPGMEGAGTVLAVGEDVADLV
PGDRVAYPTALGGYAECRTIAADRVVPLPPDISSEVAAACMLRGLTVHMLLREVHAVQPGETILVHAAAGGVGLLMCQWA
RYLGVRMIGVVSTEEKGELARQNGASDILVGYDNLAARVRKLTDGAMVPVVYDSIGKDTFVASLDCLAPRGLMVSYGNAS
GEITGISVGMLATRGSLYLTRPGLTTYIAQRPALLAGAAELFGLIAQGVLSVRIGQRFALADAAEAQRALEARTTVGSTI
LVP
>Mature_323_residues
MYRAIRIHDYGGPEVLKLETLPSPVPGRGEILIRQEAIGVNFIDIYFRTGLYKLPTLPAIPGMEGAGTVLAVGEDVADLV
PGDRVAYPTALGGYAECRTIAADRVVPLPPDISSEVAAACMLRGLTVHMLLREVHAVQPGETILVHAAAGGVGLLMCQWA
RYLGVRMIGVVSTEEKGELARQNGASDILVGYDNLAARVRKLTDGAMVPVVYDSIGKDTFVASLDCLAPRGLMVSYGNAS
GEITGISVGMLATRGSLYLTRPGLTTYIAQRPALLAGAAELFGLIAQGVLSVRIGQRFALADAAEAQRALEARTTVGSTI
LVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=314, Percent_Identity=31.2101910828025, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI13236495, Length=314, Percent_Identity=31.2101910828025, Blast_Score=141, Evalue=6e-34,
Organism=Homo sapiens, GI194239676, Length=192, Percent_Identity=39.0625, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI18379349, Length=343, Percent_Identity=30.3206997084548, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI24308257, Length=340, Percent_Identity=26.7647058823529, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI22538446, Length=268, Percent_Identity=30.2238805970149, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI22538444, Length=268, Percent_Identity=30.2238805970149, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI28557745, Length=225, Percent_Identity=32, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI67078404, Length=257, Percent_Identity=27.6264591439689, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI67078406, Length=219, Percent_Identity=28.7671232876712, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=47.5609756097561, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17507255, Length=265, Percent_Identity=30.188679245283, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988145, Length=264, Percent_Identity=26.5151515151515, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17536829, Length=238, Percent_Identity=27.7310924369748, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17556000, Length=338, Percent_Identity=25.4437869822485, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=36.4197530864198, Blast_Score=185, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6323729, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=264, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550423, Length=298, Percent_Identity=23.8255033557047, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34024; Mature: 34024

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAIRIHDYGGPEVLKLETLPSPVPGRGEILIRQEAIGVNFIDIYFRTGLYKLPTLPAI
CCEEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCEECCCCCCC
PGMEGAGTVLAVGEDVADLVPGDRVAYPTALGGYAECRTIAADRVVPLPPDISSEVAAAC
CCCCCCCEEEEECCCHHHHCCCCCEECCCCCCCHHHHHHHHCCCEECCCCCCHHHHHHHH
MLRGLTVHMLLREVHAVQPGETILVHAAAGGVGLLMCQWARYLGVRMIGVVSTEEKGELA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEEECCCCHHHHH
RQNGASDILVGYDNLAARVRKLTDGAMVPVVYDSIGKDTFVASLDCLAPRGLMVSYGNAS
HHCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHHHCCCCCEEEEECCCC
GEITGISVGMLATRGSLYLTRPGLTTYIAQRPALLAGAAELFGLIAQGVLSVRIGQRFAL
CEEEEEEEEEEEECCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEH
ADAAEAQRALEARTTVGSTILVP
HHHHHHHHHHHHHHHCCCEEECC
>Mature Secondary Structure
MYRAIRIHDYGGPEVLKLETLPSPVPGRGEILIRQEAIGVNFIDIYFRTGLYKLPTLPAI
CCEEEEEECCCCCCEEEEECCCCCCCCCCCEEEEEECCCCEEEEEEECCCCEECCCCCCC
PGMEGAGTVLAVGEDVADLVPGDRVAYPTALGGYAECRTIAADRVVPLPPDISSEVAAAC
CCCCCCCEEEEECCCHHHHCCCCCEECCCCCCCHHHHHHHHCCCEECCCCCCHHHHHHHH
MLRGLTVHMLLREVHAVQPGETILVHAAAGGVGLLMCQWARYLGVRMIGVVSTEEKGELA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCEEEEEEECCCCHHHHH
RQNGASDILVGYDNLAARVRKLTDGAMVPVVYDSIGKDTFVASLDCLAPRGLMVSYGNAS
HHCCCCEEEEEHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHHHCCCCCEEEEECCCC
GEITGISVGMLATRGSLYLTRPGLTTYIAQRPALLAGAAELFGLIAQGVLSVRIGQRFAL
CEEEEEEEEEEEECCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEH
ADAAEAQRALEARTTVGSTILVP
HHHHHHHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]