Click here to switch to the map view.

The map label for this gene is btuB [H]

Identifier: 162147018

GI number: 162147018

Start: 1213537

End: 1215978

Strand: Reverse

Name: btuB [H]

Synonym: GDI_1223

Alternate gene names: 162147018

Gene position: 1215978-1213537 (Counterclockwise)

Preceding gene: 162147019

Following gene: 162147013

Centisome position: 30.83

GC content: 65.4

Gene sequence:

>2442_bases
ATGGCGGCGGACGAAACGGCGGAAACCACGGCCTCGCAGGATACCGCCAGGAAGCGCGTCGCATCCTCCAGCCGCCAGCG
TGCGCAGGCGGCCGACGGCGCGGCCCAAATTGCCGTTCCGATGCAGGCCGCCCGGCCGGCCGATACCGGCGAGGCCATCA
TCGTGACCGGCACGCGTGAGATCGGGAAGAAGGCACGCGACAGCGTGGCGCCGATCGATATCGTATCGGCGCGGCAGCTT
GCGCAGACGGGGCAGCCGACGCTACGCGAGGCGCTGGGCCAGTTGCTGCCGTCGCTGACGCTGCCGACGGGCGGCTTCGA
TACCGGCGCGCTGACGTCGGCCTTCAGCCTGCGCGGCCTCAGCCCCAACGAGACGCTGGTACTGGTGGATGGCAAGCGGC
GCCATACCACGGCCAACCTCTATGCCGATGGCGGCCCGCAGCAGGGCACCACGCCGGTCGATATCGACATGATCCCCATG
GCGGCGATCGACCATGTGGAGATCCTGCGCGACGGGGCTTCGGCGCAATACGGGTCCGACGCCGTGGCGGGGGTGGTGAA
CATCATCCTCAAGAAGCAGGACCATGGCTTCAATGCCGAGTCGATCACCGGCATCACCGCTGCCAAGGACGGGTTCCAGC
AAGGTGTGTATCTGGATGGCGGCGCGAAGCTGGGGGCGCGCGGGTTCGTCCATGTCAGCGGCGATTTCGTGCACGAGGAC
CACACGTTCCGCAGCGCGCCGGACCTGCGGACGGGGACCAAGATCAACAAGATCCAGGGCCGGCCCGAGCAGACGCGCGA
AAGCCTGGCGATCAAGGCCGGGTACGACCTGACGGACGATATCCAGGCCTATGCGCTGGCGACCTATGCCCACCGGCATG
CCGAGGCATACCAGAATTATCGCCTGCCCGGCTCGCTTGCAGCCTATCCGCTCTATGCCGCCATCTATCCGGACGGCTAT
TCGCCGCTGGAGACGATCGATGAGGATGACTGGGAGGTCACGGCGGGCGTGAAGGGCGTCCTGCGGGGATGGAACTGGGA
CCTGTCCTCGGTCTATGGCCGCGATTATGACGCGATCGGGCTGAAGGATTCGGCGAATTTCGCGGTCGCGGCCGCGACCG
GCCGCACGCCGACGGTCATCCAGGCCCAGGGGTTCAACAATTCCCAGTGGAGCAACACGTTCGATATCAGCCGGGCGTTT
CATGTCTCCGGTTGGCCGCACAGCATCAACGTCGCCGGCGGGGCGACCTATCGCTACGAAAGCTACTCGGTCGGCACCGG
ATCGCCCGATTCGACCTATGGCAGCGGGTCGGACGCGCTGGCCGGGACCAATGCGGGCAATGCCGGCAATTTCAACCGCG
ATGTCGTCGGCGGATATGTCGATGTCTCCACGCATCTTCTGAAGAACTGGCAACTCGATCTGGCCGGGCGCTACGAGCAT
TATACCGATGTGGGGGACACCGAGACCGGCAAGGTGTCCACGCGCTATGATGCGTTCAGGTGGCTGGCGTTCCGCGCCAC
GATCTCGAACGGGTTCCATGCGCCGACGCTGGCGCAGGAGCATTACAGTTCGCTGACGCTCTCGCCCACGGCCGCGCGCG
GGCTGATCGCGGCCAATTCGCCCGGCGCGCTGGCCAACGGCGCGGCGCCGCTGAAGCCCGAGCGCTCGACCAACGCCACC
GGCGGCATCATCGTCGAGCCGGTACGGAACCTGCACGTGACGGTCGATGTCTATCAGATCAATCTGCGCGACCAGATCCT
GCCGGGCGGCAACATTACCGGCAATGCGGCGCGTTCCGCCCTGACGATGAACGGCTTTACGCTGCCTGCCGGATCGGATC
AGTGGACGGCGGCCTCGCTGTCGACCAACTGGTTTGCGAACGTGGCAAGCACGCGCACGCAGGGGCTGGACCTGACGGCG
ACCTATCCGACGCGGCTGGGCGATGTCGGGCGGATCGACTGGGATGTGGCCATCAACCTCAACCGGACCCGCCTGAGCCA
TCAGACGGACGCCGCGACGGGGCAGCCGCTCCTGTCCGCACAGAGCGTTGCCTACATCACCACGGCCTATCCGCGCAGCA
AGATGATCTTCGGCGGGCGCTTTACCCACGGGGCCTGGACGGTCGGCGTGCATGAGATCCGCTATGGCCAGACGACATCG
CAACTGACCTATTATACGGGTGCGGCCAATACGGGCTCGCTCTCCAGCACGGTGTTCCTACCCTTCCGGAACACACCGAA
ATTCATCACCAATCTGGACATCACCTATCGCGCCAACCGCAACTGGTCGTTCACGCTGGGGGCGAACAACCTGTTCGACG
CCCGGCCCAGCCGGGTGCCGGACGGGAACCGCTATCTGGGCGTGCCGCAATACTACATGAGCACGTCGCAGCTCGACATG
AATGGCGGATATTACTACCTGCGTGCCAATTTGACGCTGTAG

Upstream 100 bases:

>100_bases
ACCTGCCGGCAGAAGAACGCCTCTGGCAGGATATCGTCTCCACCCCCGGCATGCGTTGCTGGCGGCCTCGATCCTGACAG
CGCTGCCGATCGCGCAGGCG

Downstream 100 bases:

>100_bases
CAGTCTGTCACTGCGTGGAAGCGGGCTCGCACGGGCCCGCTTCCATGACGGTTGGCATCAGGCGCGGGGCACTGTCCCTG
GATCGACGCGGACGCGACCT

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 813; Mature: 812

Protein sequence:

>813_residues
MAADETAETTASQDTARKRVASSSRQRAQAADGAAQIAVPMQAARPADTGEAIIVTGTREIGKKARDSVAPIDIVSARQL
AQTGQPTLREALGQLLPSLTLPTGGFDTGALTSAFSLRGLSPNETLVLVDGKRRHTTANLYADGGPQQGTTPVDIDMIPM
AAIDHVEILRDGASAQYGSDAVAGVVNIILKKQDHGFNAESITGITAAKDGFQQGVYLDGGAKLGARGFVHVSGDFVHED
HTFRSAPDLRTGTKINKIQGRPEQTRESLAIKAGYDLTDDIQAYALATYAHRHAEAYQNYRLPGSLAAYPLYAAIYPDGY
SPLETIDEDDWEVTAGVKGVLRGWNWDLSSVYGRDYDAIGLKDSANFAVAAATGRTPTVIQAQGFNNSQWSNTFDISRAF
HVSGWPHSINVAGGATYRYESYSVGTGSPDSTYGSGSDALAGTNAGNAGNFNRDVVGGYVDVSTHLLKNWQLDLAGRYEH
YTDVGDTETGKVSTRYDAFRWLAFRATISNGFHAPTLAQEHYSSLTLSPTAARGLIAANSPGALANGAAPLKPERSTNAT
GGIIVEPVRNLHVTVDVYQINLRDQILPGGNITGNAARSALTMNGFTLPAGSDQWTAASLSTNWFANVASTRTQGLDLTA
TYPTRLGDVGRIDWDVAINLNRTRLSHQTDAATGQPLLSAQSVAYITTAYPRSKMIFGGRFTHGAWTVGVHEIRYGQTTS
QLTYYTGAANTGSLSSTVFLPFRNTPKFITNLDITYRANRNWSFTLGANNLFDARPSRVPDGNRYLGVPQYYMSTSQLDM
NGGYYYLRANLTL

Sequences:

>Translated_813_residues
MAADETAETTASQDTARKRVASSSRQRAQAADGAAQIAVPMQAARPADTGEAIIVTGTREIGKKARDSVAPIDIVSARQL
AQTGQPTLREALGQLLPSLTLPTGGFDTGALTSAFSLRGLSPNETLVLVDGKRRHTTANLYADGGPQQGTTPVDIDMIPM
AAIDHVEILRDGASAQYGSDAVAGVVNIILKKQDHGFNAESITGITAAKDGFQQGVYLDGGAKLGARGFVHVSGDFVHED
HTFRSAPDLRTGTKINKIQGRPEQTRESLAIKAGYDLTDDIQAYALATYAHRHAEAYQNYRLPGSLAAYPLYAAIYPDGY
SPLETIDEDDWEVTAGVKGVLRGWNWDLSSVYGRDYDAIGLKDSANFAVAAATGRTPTVIQAQGFNNSQWSNTFDISRAF
HVSGWPHSINVAGGATYRYESYSVGTGSPDSTYGSGSDALAGTNAGNAGNFNRDVVGGYVDVSTHLLKNWQLDLAGRYEH
YTDVGDTETGKVSTRYDAFRWLAFRATISNGFHAPTLAQEHYSSLTLSPTAARGLIAANSPGALANGAAPLKPERSTNAT
GGIIVEPVRNLHVTVDVYQINLRDQILPGGNITGNAARSALTMNGFTLPAGSDQWTAASLSTNWFANVASTRTQGLDLTA
TYPTRLGDVGRIDWDVAINLNRTRLSHQTDAATGQPLLSAQSVAYITTAYPRSKMIFGGRFTHGAWTVGVHEIRYGQTTS
QLTYYTGAANTGSLSSTVFLPFRNTPKFITNLDITYRANRNWSFTLGANNLFDARPSRVPDGNRYLGVPQYYMSTSQLDM
NGGYYYLRANLTL
>Mature_812_residues
AADETAETTASQDTARKRVASSSRQRAQAADGAAQIAVPMQAARPADTGEAIIVTGTREIGKKARDSVAPIDIVSARQLA
QTGQPTLREALGQLLPSLTLPTGGFDTGALTSAFSLRGLSPNETLVLVDGKRRHTTANLYADGGPQQGTTPVDIDMIPMA
AIDHVEILRDGASAQYGSDAVAGVVNIILKKQDHGFNAESITGITAAKDGFQQGVYLDGGAKLGARGFVHVSGDFVHEDH
TFRSAPDLRTGTKINKIQGRPEQTRESLAIKAGYDLTDDIQAYALATYAHRHAEAYQNYRLPGSLAAYPLYAAIYPDGYS
PLETIDEDDWEVTAGVKGVLRGWNWDLSSVYGRDYDAIGLKDSANFAVAAATGRTPTVIQAQGFNNSQWSNTFDISRAFH
VSGWPHSINVAGGATYRYESYSVGTGSPDSTYGSGSDALAGTNAGNAGNFNRDVVGGYVDVSTHLLKNWQLDLAGRYEHY
TDVGDTETGKVSTRYDAFRWLAFRATISNGFHAPTLAQEHYSSLTLSPTAARGLIAANSPGALANGAAPLKPERSTNATG
GIIVEPVRNLHVTVDVYQINLRDQILPGGNITGNAARSALTMNGFTLPAGSDQWTAASLSTNWFANVASTRTQGLDLTAT
YPTRLGDVGRIDWDVAINLNRTRLSHQTDAATGQPLLSAQSVAYITTAYPRSKMIFGGRFTHGAWTVGVHEIRYGQTTSQ
LTYYTGAANTGSLSSTVFLPFRNTPKFITNLDITYRANRNWSFTLGANNLFDARPSRVPDGNRYLGVPQYYMSTSQLDMN
GGYYYLRANLTL

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=159, Percent_Identity=31.4465408805031, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87225; Mature: 87094

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADETAETTASQDTARKRVASSSRQRAQAADGAAQIAVPMQAARPADTGEAIIVTGTRE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEECCHH
IGKKARDSVAPIDIVSARQLAQTGQPTLREALGQLLPSLTLPTGGFDTGALTSAFSLRGL
HHHHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEECCC
SPNETLVLVDGKRRHTTANLYADGGPQQGTTPVDIDMIPMAAIDHVEILRDGASAQYGSD
CCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCH
AVAGVVNIILKKQDHGFNAESITGITAAKDGFQQGVYLDGGAKLGARGFVHVSGDFVHED
HHHHHHHHHEECCCCCCCHHHEEEEEHHCCHHHCCEEEECCCCCCCCEEEEECCCEEECC
HTFRSAPDLRTGTKINKIQGRPEQTRESLAIKAGYDLTDDIQAYALATYAHRHAEAYQNY
CCCCCCCCCCCCCEEEECCCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
RLPGSLAAYPLYAAIYPDGYSPLETIDEDDWEVTAGVKGVLRGWNWDLSSVYGRDYDAIG
CCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEECCHHHHHCCCCCCHHHHCCCCCCEEC
LKDSANFAVAAATGRTPTVIQAQGFNNSQWSNTFDISRAFHVSGWPHSINVAGGATYRYE
CCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEECCEEEEECCCCCEEEECCCEEEEEE
SYSVGTGSPDSTYGSGSDALAGTNAGNAGNFNRDVVGGYVDVSTHLLKNWQLDLAGRYEH
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCEEECCCCCC
YTDVGDTETGKVSTRYDAFRWLAFRATISNGFHAPTLAQEHYSSLTLSPTAARGLIAANS
CCCCCCCCCCCEEEHHHHEEEEEEEEECCCCCCCCCHHHHHHCCEEECCHHHCCEEEECC
PGALANGAAPLKPERSTNATGGIIVEPVRNLHVTVDVYQINLRDQILPGGNITGNAARSA
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEEECCEECCCCCCCCHHHCCE
LTMNGFTLPAGSDQWTAASLSTNWFANVASTRTQGLDLTATYPTRLGDVGRIDWDVAINL
EEECCEECCCCCCCEEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEEEE
NRTRLSHQTDAATGQPLLSAQSVAYITTAYPRSKMIFGGRFTHGAWTVGVHEIRYGQTTS
CHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCEECCCEEEEEEEEEECCCCCC
QLTYYTGAANTGSLSSTVFLPFRNTPKFITNLDITYRANRNWSFTLGANNLFDARPSRVP
EEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCCCCCC
DGNRYLGVPQYYMSTSQLDMNGGYYYLRANLTL
CCCEEECCCHHHHCCCEEECCCCEEEEEEEECC
>Mature Secondary Structure 
AADETAETTASQDTARKRVASSSRQRAQAADGAAQIAVPMQAARPADTGEAIIVTGTRE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCCCEEEEECCHH
IGKKARDSVAPIDIVSARQLAQTGQPTLREALGQLLPSLTLPTGGFDTGALTSAFSLRGL
HHHHHHCCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHEECCC
SPNETLVLVDGKRRHTTANLYADGGPQQGTTPVDIDMIPMAAIDHVEILRDGASAQYGSD
CCCCEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCH
AVAGVVNIILKKQDHGFNAESITGITAAKDGFQQGVYLDGGAKLGARGFVHVSGDFVHED
HHHHHHHHHEECCCCCCCHHHEEEEEHHCCHHHCCEEEECCCCCCCCEEEEECCCEEECC
HTFRSAPDLRTGTKINKIQGRPEQTRESLAIKAGYDLTDDIQAYALATYAHRHAEAYQNY
CCCCCCCCCCCCCEEEECCCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
RLPGSLAAYPLYAAIYPDGYSPLETIDEDDWEVTAGVKGVLRGWNWDLSSVYGRDYDAIG
CCCCCCCCCEEEEEECCCCCCHHHHCCCCCCEEECCHHHHHCCCCCCHHHHCCCCCCEEC
LKDSANFAVAAATGRTPTVIQAQGFNNSQWSNTFDISRAFHVSGWPHSINVAGGATYRYE
CCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEECCEEEEECCCCCEEEECCCEEEEEE
SYSVGTGSPDSTYGSGSDALAGTNAGNAGNFNRDVVGGYVDVSTHLLKNWQLDLAGRYEH
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHCCCEEECCCCCC
YTDVGDTETGKVSTRYDAFRWLAFRATISNGFHAPTLAQEHYSSLTLSPTAARGLIAANS
CCCCCCCCCCCEEEHHHHEEEEEEEEECCCCCCCCCHHHHHHCCEEECCHHHCCEEEECC
PGALANGAAPLKPERSTNATGGIIVEPVRNLHVTVDVYQINLRDQILPGGNITGNAARSA
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEEECCEECCCCCCCCHHHCCE
LTMNGFTLPAGSDQWTAASLSTNWFANVASTRTQGLDLTATYPTRLGDVGRIDWDVAINL
EEECCEECCCCCCCEEEEECCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEEEEEEE
NRTRLSHQTDAATGQPLLSAQSVAYITTAYPRSKMIFGGRFTHGAWTVGVHEIRYGQTTS
CHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCEECCCEEEEEEEEEECCCCCC
QLTYYTGAANTGSLSSTVFLPFRNTPKFITNLDITYRANRNWSFTLGANNLFDARPSRVP
EEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCCCCCC
DGNRYLGVPQYYMSTSQLDMNGGYYYLRANLTL
CCCEEECCCHHHHCCCEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA