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The map label for this gene is oxyR [H]

Identifier: 162146597

GI number: 162146597

Start: 792395

End: 793342

Strand: Direct

Name: oxyR [H]

Synonym: GDI_0775

Alternate gene names: 162146597

Gene position: 792395-793342 (Clockwise)

Preceding gene: 162146594

Following gene: 162146598

Centisome position: 20.09

GC content: 66.56

Gene sequence:

>948_bases
ATGGAAAAGACCTACACTCCCCTGTCTGGCCTGTCGCTGCGCGACATCGAATATGCCGTGGCCGTCGATGATCTGCGAAA
CTTCTCCCGCGCCGCCGAACGATGTGGCGTCAGCCAGGCGGGGCTGTCCGAGCAGATCCGCAAGCTGGAAAATCTCCTGG
GCGTCGTCTTGTTCGAACGTACGCGACGGCATGTGAAGCCGACACCGGAAGGTATACGGCTCCTGGAACGGGCAAGGGAT
GTCGTGACCGCCGCCCGGATGATGCTGGAGGCGGCGCACATGCAGTCCGGGCCGCTGAACGGAATCCTGCGCATCGGCGT
GATCGCGACGCTGGGGCCCTACTACATTCCCAGCATGCTGCCGCTGCTGCGCAAGAGCTATCCTGATCTCAGGCTGCAGG
TGACGGACGGCCTGACCGGACCACTCCTGGCGAAGTTGCAGCAGGACGAGCTCGACCTTGTATTCGCGGCGCTGCCGGTT
TCGGAAAAATCGTTCATGGATTGCGCCCTTTTCGAGGAACCGTTCGTCGCCGCCGTTCCGTCCGGCCATCCGCTTTCCCG
CAAGCGGTCGCTGGCGACGCGTGACCTGGACGGGCCCGAACTCCTGCTGCTCGAAGACGGTCACTGCCTGCGCGACCAGG
CGCTTGCGCTGTGCGGCCTGCCGACGCAGGCGCGCGCGCGGCAGCGGCTTGCGACCAGCCTGGAAATGCTCTGGCACATG
ATCGGCGCCGGCGAGGGCCATTCCCTGATCCCCCATCTGGCGCTGCGCAATCGCGGCGAATGGCGCGGCCTCATCGCCGT
CAGGCCCCTGGCGGATGCCAGCCGGACGATCGGCGCCGTCTGGCGCAAATCGGACCCGCGCGGGCCGGCCTTTGCCGAGC
TTGGCGATTTCCTGCGCCGGCACGTTCCCGAAGGGTGCCGCCCGTGCCAGGACGGGCCGGAAGCATAG

Upstream 100 bases:

>100_bases
GAACGGGTGTCCGACAAATTTCCCTCGGGCGGAAATCGTTTGTCCCGATGGGAATTATAGGTAAAACCATTTTATGGGAT
TGGATTGAGCGATCGTACTT

Downstream 100 bases:

>100_bases
GTCGCGACGTGCCGCGTCCCTGACGATATTTTATCGATTCCATTGTGGAAAAGGAAACCTGTTATCGGGTGTTCCTATCA
CGGAATTCGATACTATCTGT

Product: hydrogen peroxide-inducible genes activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MEKTYTPLSGLSLRDIEYAVAVDDLRNFSRAAERCGVSQAGLSEQIRKLENLLGVVLFERTRRHVKPTPEGIRLLERARD
VVTAARMMLEAAHMQSGPLNGILRIGVIATLGPYYIPSMLPLLRKSYPDLRLQVTDGLTGPLLAKLQQDELDLVFAALPV
SEKSFMDCALFEEPFVAAVPSGHPLSRKRSLATRDLDGPELLLLEDGHCLRDQALALCGLPTQARARQRLATSLEMLWHM
IGAGEGHSLIPHLALRNRGEWRGLIAVRPLADASRTIGAVWRKSDPRGPAFAELGDFLRRHVPEGCRPCQDGPEA

Sequences:

>Translated_315_residues
MEKTYTPLSGLSLRDIEYAVAVDDLRNFSRAAERCGVSQAGLSEQIRKLENLLGVVLFERTRRHVKPTPEGIRLLERARD
VVTAARMMLEAAHMQSGPLNGILRIGVIATLGPYYIPSMLPLLRKSYPDLRLQVTDGLTGPLLAKLQQDELDLVFAALPV
SEKSFMDCALFEEPFVAAVPSGHPLSRKRSLATRDLDGPELLLLEDGHCLRDQALALCGLPTQARARQRLATSLEMLWHM
IGAGEGHSLIPHLALRNRGEWRGLIAVRPLADASRTIGAVWRKSDPRGPAFAELGDFLRRHVPEGCRPCQDGPEA
>Mature_315_residues
MEKTYTPLSGLSLRDIEYAVAVDDLRNFSRAAERCGVSQAGLSEQIRKLENLLGVVLFERTRRHVKPTPEGIRLLERARD
VVTAARMMLEAAHMQSGPLNGILRIGVIATLGPYYIPSMLPLLRKSYPDLRLQVTDGLTGPLLAKLQQDELDLVFAALPV
SEKSFMDCALFEEPFVAAVPSGHPLSRKRSLATRDLDGPELLLLEDGHCLRDQALALCGLPTQARARQRLATSLEMLWHM
IGAGEGHSLIPHLALRNRGEWRGLIAVRPLADASRTIGAVWRKSDPRGPAFAELGDFLRRHVPEGCRPCQDGPEA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=40.0684931506849, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=28.6666666666667, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI157672245, Length=205, Percent_Identity=31.7073170731707, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787879, Length=299, Percent_Identity=29.4314381270903, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788748, Length=247, Percent_Identity=28.3400809716599, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=27.112676056338, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=218, Percent_Identity=27.5229357798165, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=25.9109311740891, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=311, Percent_Identity=25.08038585209, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788296, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34771; Mature: 34771

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTYTPLSGLSLRDIEYAVAVDDLRNFSRAAERCGVSQAGLSEQIRKLENLLGVVLFER
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TRRHVKPTPEGIRLLERARDVVTAARMMLEAAHMQSGPLNGILRIGVIATLGPYYIPSML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
PLLRKSYPDLRLQVTDGLTGPLLAKLQQDELDLVFAALPVSEKSFMDCALFEEPFVAAVP
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHCCCCEEECC
SGHPLSRKRSLATRDLDGPELLLLEDGHCLRDQALALCGLPTQARARQRLATSLEMLWHM
CCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGAGEGHSLIPHLALRNRGEWRGLIAVRPLADASRTIGAVWRKSDPRGPAFAELGDFLRR
HCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HVPEGCRPCQDGPEA
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKTYTPLSGLSLRDIEYAVAVDDLRNFSRAAERCGVSQAGLSEQIRKLENLLGVVLFER
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
TRRHVKPTPEGIRLLERARDVVTAARMMLEAAHMQSGPLNGILRIGVIATLGPYYIPSML
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
PLLRKSYPDLRLQVTDGLTGPLLAKLQQDELDLVFAALPVSEKSFMDCALFEEPFVAAVP
HHHHCCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHCCCCEEECC
SGHPLSRKRSLATRDLDGPELLLLEDGHCLRDQALALCGLPTQARARQRLATSLEMLWHM
CCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IGAGEGHSLIPHLALRNRGEWRGLIAVRPLADASRTIGAVWRKSDPRGPAFAELGDFLRR
HCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
HVPEGCRPCQDGPEA
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA