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The map label for this gene is yhdN [H]

Identifier: 162146563

GI number: 162146563

Start: 757661

End: 758644

Strand: Direct

Name: yhdN [H]

Synonym: GDI_0740

Alternate gene names: 162146563

Gene position: 757661-758644 (Clockwise)

Preceding gene: 162146561

Following gene: 162146567

Centisome position: 19.21

GC content: 67.78

Gene sequence:

>984_bases
ATGTCGATGGAAACCCTTGTCATTGAAGGCATTCCCTTTCCCGTATCGCGAATCGCGCTGGGAACCTGGGCGATCGGCGG
CTGGATGTGGGGTGGCCCCGACGACCGGAAGGCCATTGCCACGATTCACGAGGCCCTGGATCTGGGCATCACCCTGATCG
ACACCGCCCCGGTCTACGGTTTCGGCCATTCCGAGGAGGTCGTGGGCCAGGCCCTGGCCGGCCGCCGCGACAAGGTGGCC
ATCGCGACCAAGGTCGGGCTGGACTGGAAGGACGGCAAGCCGTTCCGCAACGCCACGCCCGCCCGTATCCGCACGGAAAT
CGAGGATTCGCTGCGCCGCCTGCGCACCGACCGGATCGATCTGTACCAGGTGCACTGGCCCGATCCCTCGGTGCCGATCG
ACGAGACGGCGCGGGAACTGGAACGGCTGCATCGCGAAGGCAAGGTGCTGGCGCTGGGCGTCAGCAATTTTTCCGTGGCG
CAGATGGAGCAGTTCCGCGCGGTGGCCCCCCTCGCGGCCGTCCAGCCCCCCTATAACGTGTTCGAGCGCGAGATCGAATC
CGACATCCTGCCCTGGTCGGTCCGTCACGGGCTGGCCGTCCTGGCCTATGGTCCGCTCTGCCGGGGCCTGCTCTCGGGCC
GGATGACGGCGGACACCGTCTTCGGCGTCGACGACCTGCGCAGCGCCGATCCCAAATTCCACGCTCCGCGCTTCGCCCAG
TATCTGGCCGCCGTGACCGCGCTGCAGGATTTCGCGCGCCAGCGCTTCAATCGTTCGGTCCTGGCGCTGGCGATCCGCTG
GGTGCTGGACCAGGGGCCGACTATCGCGCTGTGGGGCGCGCGCAAGCCCGAGCAGATTGCCGGTATCGACCAGGCCATCG
GCTGGACGCTGTCGGCGGACGACAAGGCGGAAATCGACCGGATCCTCGCCCGGCACATCACCGATCCGGTCGGGCCGGAA
TTCATGGCGCCTCCGGGCGGCTGA

Upstream 100 bases:

>100_bases
CCCGGCCTATGGTGGCCGCGGCATATCCTGCCCCCCGCCGATTGGGGGTATGAGCCAAGGCGCTTGCGTCGCCGGCGGCA
GGACAGGAAGGACAAAGACC

Downstream 100 bases:

>100_bases
AGGCGAAAGACCCGATCGTCCCGGGCCGGGGCGGCCCGGGGCGCGTCACGCCGGCATGAAGCAGACCGACAGCGTGCGCA
CGCCCTGGGCCCCCCGGATG

Product: oxidoreductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSMETLVIEGIPFPVSRIALGTWAIGGWMWGGPDDRKAIATIHEALDLGITLIDTAPVYGFGHSEEVVGQALAGRRDKVA
IATKVGLDWKDGKPFRNATPARIRTEIEDSLRRLRTDRIDLYQVHWPDPSVPIDETARELERLHREGKVLALGVSNFSVA
QMEQFRAVAPLAAVQPPYNVFEREIESDILPWSVRHGLAVLAYGPLCRGLLSGRMTADTVFGVDDLRSADPKFHAPRFAQ
YLAAVTALQDFARQRFNRSVLALAIRWVLDQGPTIALWGARKPEQIAGIDQAIGWTLSADDKAEIDRILARHITDPVGPE
FMAPPGG

Sequences:

>Translated_327_residues
MSMETLVIEGIPFPVSRIALGTWAIGGWMWGGPDDRKAIATIHEALDLGITLIDTAPVYGFGHSEEVVGQALAGRRDKVA
IATKVGLDWKDGKPFRNATPARIRTEIEDSLRRLRTDRIDLYQVHWPDPSVPIDETARELERLHREGKVLALGVSNFSVA
QMEQFRAVAPLAAVQPPYNVFEREIESDILPWSVRHGLAVLAYGPLCRGLLSGRMTADTVFGVDDLRSADPKFHAPRFAQ
YLAAVTALQDFARQRFNRSVLALAIRWVLDQGPTIALWGARKPEQIAGIDQAIGWTLSADDKAEIDRILARHITDPVGPE
FMAPPGG
>Mature_326_residues
SMETLVIEGIPFPVSRIALGTWAIGGWMWGGPDDRKAIATIHEALDLGITLIDTAPVYGFGHSEEVVGQALAGRRDKVAI
ATKVGLDWKDGKPFRNATPARIRTEIEDSLRRLRTDRIDLYQVHWPDPSVPIDETARELERLHREGKVLALGVSNFSVAQ
MEQFRAVAPLAAVQPPYNVFEREIESDILPWSVRHGLAVLAYGPLCRGLLSGRMTADTVFGVDDLRSADPKFHAPRFAQY
LAAVTALQDFARQRFNRSVLALAIRWVLDQGPTIALWGARKPEQIAGIDQAIGWTLSADDKAEIDRILARHITDPVGPEF
MAPPGG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI41327764, Length=212, Percent_Identity=33.9622641509434, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI41152114, Length=176, Percent_Identity=34.0909090909091, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223718702, Length=178, Percent_Identity=33.1460674157303, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=28.0254777070064, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=28.1150159744409, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436962, Length=317, Percent_Identity=26.1829652996845, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI27436964, Length=317, Percent_Identity=26.1829652996845, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27436966, Length=292, Percent_Identity=26.027397260274, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI223718708, Length=129, Percent_Identity=35.6589147286822, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436971, Length=289, Percent_Identity=26.2975778546713, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788070, Length=304, Percent_Identity=36.8421052631579, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788081, Length=201, Percent_Identity=36.81592039801, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081735, Length=314, Percent_Identity=30.8917197452229, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=29.0909090909091, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=29.1545189504373, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994888, Length=174, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786400, Length=183, Percent_Identity=30.6010928961749, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787674, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082198, Length=200, Percent_Identity=29, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=217, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=225, Percent_Identity=28.4444444444444, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=317, Percent_Identity=28.391167192429, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=27.3648648648649, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=349, Percent_Identity=24.0687679083095, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=175, Percent_Identity=33.7142857142857, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646155, Length=158, Percent_Identity=36.7088607594937, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646159, Length=162, Percent_Identity=36.4197530864198, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640980, Length=343, Percent_Identity=26.2390670553936, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549126, Length=343, Percent_Identity=27.1137026239067, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36082; Mature: 35951

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMETLVIEGIPFPVSRIALGTWAIGGWMWGGPDDRKAIATIHEALDLGITLIDTAPVYG
CCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCC
FGHSEEVVGQALAGRRDKVAIATKVGLDWKDGKPFRNATPARIRTEIEDSLRRLRTDRID
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
LYQVHWPDPSVPIDETARELERLHREGKVLALGVSNFSVAQMEQFRAVAPLAAVQPPYNV
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCCHHH
FEREIESDILPWSVRHGLAVLAYGPLCRGLLSGRMTADTVFGVDDLRSADPKFHAPRFAQ
HHHHHHHCCCCHHHHCCEEEEHHHHHHHHHHHCCCCHHHEECHHHHHCCCCCCCCHHHHH
YLAAVTALQDFARQRFNRSVLALAIRWVLDQGPTIALWGARKPEQIAGIDQAIGWTLSAD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCHHHHHCCEECCC
DKAEIDRILARHITDPVGPEFMAPPGG
CHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SMETLVIEGIPFPVSRIALGTWAIGGWMWGGPDDRKAIATIHEALDLGITLIDTAPVYG
CCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCC
FGHSEEVVGQALAGRRDKVAIATKVGLDWKDGKPFRNATPARIRTEIEDSLRRLRTDRID
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCE
LYQVHWPDPSVPIDETARELERLHREGKVLALGVSNFSVAQMEQFRAVAPLAAVQPPYNV
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHHHCCCCHHH
FEREIESDILPWSVRHGLAVLAYGPLCRGLLSGRMTADTVFGVDDLRSADPKFHAPRFAQ
HHHHHHHCCCCHHHHCCEEEEHHHHHHHHHHHCCCCHHHEECHHHHHCCCCCCCCHHHHH
YLAAVTALQDFARQRFNRSVLALAIRWVLDQGPTIALWGARKPEQIAGIDQAIGWTLSAD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCHHHHHCCEECCC
DKAEIDRILARHITDPVGPEFMAPPGG
CHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]