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The map label for this gene is gntR [H]

Identifier: 162146506

GI number: 162146506

Start: 692554

End: 693237

Strand: Direct

Name: gntR [H]

Synonym: GDI_0682

Alternate gene names: 162146506

Gene position: 692554-693237 (Clockwise)

Preceding gene: 162146505

Following gene: 162146507

Centisome position: 17.56

GC content: 64.77

Gene sequence:

>684_bases
ATGACGTCGCCGACCCGTATCCCGCGCCTGAACCTGCACGATACGGTCACGACCGCATTGCGCGGCATGATCCTGGATGG
CGTGCTGGTGCCGGGTGAAAAAATCGCCGAACGCGGCCTGTGCGACCGGTTCGGCATTTCCCGCACGCCGCTACGCGAGG
CGCTGAAGGTGCTGGCGGCCGAGGGGCTGGTCGAATTGCTGCCGCGCCGCGGCGCCATCGTCGCCCAGATCACGGAATCC
GATATCCGCGATCTCTTCCCCATCATGGGCGCGTTGGAAGGGCTGGCCGGCACGTTGGCCTGCGCGCGGGTGACGCCGCG
CGACATCCAGCATCTGCGTACCCTGCATGAACAGATGATCGACAGTTACGAACGGCGTGACGAACATCGCTACCTGCGCC
AGAACCGGCGCATCCATGAAGCGATTTTCGCCATGGCCGCCAATCCCGCACTGTCGGAACTCTATCAGCAGGTTCTGACC
CGCATTCATTCCTGCCGCTTCATCCTGAAGAAATGCGACAGCGACTGGGCGGTGGCGGTGGCGGAGCATGCCGCGATCAT
GGATGCGCTGGCACGGCGCGACGGGGCGCTGCTGTCGCGCCTGATGCAGGATCACATCACGGGGACCAGCGCGCGGATCG
CGCTGGCCGCGCTGGGCGGGGATGAAAAACAGGATGCTGTATGA

Upstream 100 bases:

>100_bases
GCCCACGCTGCCGATTCACACTGTCCGCAACGCGCATGGACGCTAACATGCGGCCCGCCGCAAGGGCCTGCCGCCTACCC
ACCCCGAGAGTATATTCGTC

Downstream 100 bases:

>100_bases
TTTCGATGGCCGCGCGCCCGACCTGTCGCCCGAAGCGGGCTACGTGGCGCCGAACGCGACTCTGATCGGCGCCGTTACGG
TGGCGGCCGCCGCCAGCATC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTSPTRIPRLNLHDTVTTALRGMILDGVLVPGEKIAERGLCDRFGISRTPLREALKVLAAEGLVELLPRRGAIVAQITES
DIRDLFPIMGALEGLAGTLACARVTPRDIQHLRTLHEQMIDSYERRDEHRYLRQNRRIHEAIFAMAANPALSELYQQVLT
RIHSCRFILKKCDSDWAVAVAEHAAIMDALARRDGALLSRLMQDHITGTSARIALAALGGDEKQDAV

Sequences:

>Translated_227_residues
MTSPTRIPRLNLHDTVTTALRGMILDGVLVPGEKIAERGLCDRFGISRTPLREALKVLAAEGLVELLPRRGAIVAQITES
DIRDLFPIMGALEGLAGTLACARVTPRDIQHLRTLHEQMIDSYERRDEHRYLRQNRRIHEAIFAMAANPALSELYQQVLT
RIHSCRFILKKCDSDWAVAVAEHAAIMDALARRDGALLSRLMQDHITGTSARIALAALGGDEKQDAV
>Mature_226_residues
TSPTRIPRLNLHDTVTTALRGMILDGVLVPGEKIAERGLCDRFGISRTPLREALKVLAAEGLVELLPRRGAIVAQITESD
IRDLFPIMGALEGLAGTLACARVTPRDIQHLRTLHEQMIDSYERRDEHRYLRQNRRIHEAIFAMAANPALSELYQQVLTR
IHSCRFILKKCDSDWAVAVAEHAAIMDALARRDGALLSRLMQDHITGTSARIALAALGGDEKQDAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787821, Length=215, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48994961, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081914, Length=162, Percent_Identity=26.5432098765432, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994955, Length=211, Percent_Identity=27.0142180094787, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000485
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25189; Mature: 25057

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTRIPRLNLHDTVTTALRGMILDGVLVPGEKIAERGLCDRFGISRTPLREALKVLAA
CCCCCCCCCCCHHHHHHHHHHHHHHHCEECCCHHHHHCCCHHHCCCCCCCHHHHHHHHHH
EGLVELLPRRGAIVAQITESDIRDLFPIMGALEGLAGTLACARVTPRDIQHLRTLHEQMI
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DSYERRDEHRYLRQNRRIHEAIFAMAANPALSELYQQVLTRIHSCRFILKKCDSDWAVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AEHAAIMDALARRDGALLSRLMQDHITGTSARIALAALGGDEKQDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSPTRIPRLNLHDTVTTALRGMILDGVLVPGEKIAERGLCDRFGISRTPLREALKVLAA
CCCCCCCCCCHHHHHHHHHHHHHHHCEECCCHHHHHCCCHHHCCCCCCCHHHHHHHHHH
EGLVELLPRRGAIVAQITESDIRDLFPIMGALEGLAGTLACARVTPRDIQHLRTLHEQMI
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DSYERRDEHRYLRQNRRIHEAIFAMAANPALSELYQQVLTRIHSCRFILKKCDSDWAVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AEHAAIMDALARRDGALLSRLMQDHITGTSARIALAALGGDEKQDAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]