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The map label for this gene is mdtC [H]

Identifier: 162146471

GI number: 162146471

Start: 656133

End: 658592

Strand: Reverse

Name: mdtC [H]

Synonym: GDI_0647

Alternate gene names: 162146471

Gene position: 658592-656133 (Counterclockwise)

Preceding gene: 162146472

Following gene: 162146470

Centisome position: 16.7

GC content: 67.8

Gene sequence:

>2460_bases
ATGTCGGTGACGGGCCTCTTTATCCGCCGGCCGGTGGCGACGACGCTGCTGACGCTGGCCTGCGTCCTGTGCGGCGTCGT
CGGCTATCTGACCCTGCCGGTCGCCGACCTGCCGAACATCGATTTTCCGGTGATCCAGGTCCAGGCGCAGGAACCCGGCG
GCTCGCCCGAACAGATGGCCAGTTCGGTCGCCGCACCGCTGGAACGCCATCTGGGCGAAATCGCGGGCCTGGAGGAAATG
ACGTCGCAATCCAGCACAGGCCCGGTCCGGCTGACCCTGCAGTTCGCGCTGTCGCGCGACGTCAACGGCGCGGCCCGCGA
TGTCGAGGCCGCGATCCAGGCCGCGCGCGCCGACCTGCCGACGACGCTGCGGCAGAACCCGCAATATTCCAAGGCGAACC
CGAACGACCCGCCTGCCCTGCTGCTGGCGCTGACATCCGACACCATGCCGCTGCCGCAGGTCTACGACCAGGCGTCGAGC
CTGATCCTGCCGCGCCTGTCGCAGGTCCGGGGCGTGGGGCTGGTGCAGCTCAGCGGCAGCGCGCTGCCCGCCGTGCGGGT
CGAGATCGATCCGCAGGCGCTGTACAAGTTCGGGATCGGGTTCGAGGACATCCGCGCCGCCCTCGCCTCGGCCAACGCCT
ATACGCCCAAGGGCTTCATCGACCAGGACGGGCAGCGCCTGACGCTGGAGACCAACGACCAGGCCCGCGACGCCCAGGCC
TATCGCGACCTGGTCATCGCCTATCGCAACGGCCGCGCCGTACGCCTGACCGACGTGGCGCAGGTGGTGGACGGGGTCGA
GGACGTGCGCAATGCGGGATATTACAACCGCAAGCCGGCCATCGTGGTGCAGGTCTTCATGCAGGCCGGCGGCAATATCG
TGCAGGCCCTGGACCAGATCCATGCCGAGATGCCGCAACTGGAGGCCGGCCTGCCGGCGGCGATCCGGATGCAGACCTTC
ATGGACCGGTCGATGACCATCCGCGCGTCGCTGGCCGACACGCGCATGACGCTGGTCCTGTCGGTGGTGCTGGTGGTGCT
GACGGTGCTGCTGTTCCTGGGCACGCTGGGGGTGATCAGCCTGCTGGGCTATTCGCTGGACAACATGTCGCTGATGGCCC
TGACGATTTCCACCGGCTTCGTTGTCGATGATGCCATCGTGGTGCTGGAAAACGTCACCCGCCACGTGGAGAAGGGCGAT
CCCCCCCTTCGAGGCCGCGCTGCGCGGCGCGGGTCGTCGAACCAGGGGAACCTGTTCATCGTCCTGCCCGACAAGTCGAA
GCGCGGCCATCCGCCTTCGACCACCATCGGGAATCTCAACCGCCGGTCGCATTTCATGCCGGGGCACGGTTCTCACGCGC
TGCTGCGCAGCGCGATCCGCGTCGGCGCGCGGCCCAGCAACGCTGGGTATCAATATACCTTGCAGGGCAACGACACGGCC
GCGCTGTACGACTGGACGCAGAAGCTGGTCACCGCCCTGTCCGCGCAGCCGGAACTGGCGGACGTGTCGTCCGACGTGCT
GCTGGGCGACCTGGCGCTGGATGTCGCGATCGACCGCGACACGGGGGCCCGCACGCAACTGACGCCGCAATTGATCGCCA
ACACATTGTATGATGCCTACGGCCAGCGCCCGGCCTCGATCATCTACAATCATTTGCACCAGTATCGCGTGGTGATGGAG
GCCGCGCCCCGTTTCTGGCAGGACCCAGCCTCGCTCCGCCAGGTGTGGGTTAGTGTCGCGGGCGGCACGGCGCAGGGGGG
CACCCAGGCGAACACCATCCGCGTGCCGCTGGCGACGGCCACCACGGCCACCACGGCCGCGGCGCAGAGTGCCGCGTCCT
TCACCAACCAGATCGCCAACACGCTGGCGGGCGACCATTCGGCATCGAACGGTTCGGCGGTCTCGACGGGCGCCGAAACC
ATGGTCCCGCTGCAGGTGGTCAGCCAGACCACGCCGGGGAACATCGCGCTGGCCGTCAATCATGAGGGACAGGCTGTCGC
GGCCACGATTTCGTTCAACCTGCCGACCGGCGTGCCGCTGGGACGGGCCATCCAGGTCGTCGACGCCCAGGTCCGGCGCC
TGAAGATGCCCCCGAGCATCCATGGCGCCTTCAGCGGCAATGCCGCGCAACTGCAGAATTCCGCCAGCAGCGAGACCCTG
CTGATCATGGCCGCGCTGGCCGCGGTCTACATGGTCCTGGGAATCCTGTACGAAAGCTACCTGCACCCCCTGACCATCCT
GTCCACCCTGCCCTCGGCGGGGGTCGGCGCCCTGGTGGCCCTGTGGGTATTCGGGCAGCAATTCTCGCTGATGGCCATCA
TCGGGGGGCTGGCGGTCTGCCAGGCCCTGACCCTGTTCACGACCCCCATCGTCTACCTGACCCTGGAACAGATGGCCCGC
CGCGTGACGGCATGGCGCGGGACCATGCCGCCCGGCCATCCCAATACGGGTCTGTATTGA

Upstream 100 bases:

>100_bases
GCGCCCTTGCGGACCATGCGGCCATGGGCAACATGACGGTGCAGTACCCGCGTCCGGCCCCCCGGCGCCGGATGGCCTTC
CCGGGGCAGGGAAACCGCAC

Downstream 100 bases:

>100_bases
TATCTATTGTGTATGCGATAGAATACCAGGGGACCTATTCGGGGCAGCGTCCAACGGCCCGATCCGAAACGGAGTTGAGA
CGTGACTGATCATCCCCCGG

Product: multidrug resistance protein

Products: NA

Alternate protein names: Multidrug transporter MdtC [H]

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MSVTGLFIRRPVATTLLTLACVLCGVVGYLTLPVADLPNIDFPVIQVQAQEPGGSPEQMASSVAAPLERHLGEIAGLEEM
TSQSSTGPVRLTLQFALSRDVNGAARDVEAAIQAARADLPTTLRQNPQYSKANPNDPPALLLALTSDTMPLPQVYDQASS
LILPRLSQVRGVGLVQLSGSALPAVRVEIDPQALYKFGIGFEDIRAALASANAYTPKGFIDQDGQRLTLETNDQARDAQA
YRDLVIAYRNGRAVRLTDVAQVVDGVEDVRNAGYYNRKPAIVVQVFMQAGGNIVQALDQIHAEMPQLEAGLPAAIRMQTF
MDRSMTIRASLADTRMTLVLSVVLVVLTVLLFLGTLGVISLLGYSLDNMSLMALTISTGFVVDDAIVVLENVTRHVEKGD
PPLRGRAARRGSSNQGNLFIVLPDKSKRGHPPSTTIGNLNRRSHFMPGHGSHALLRSAIRVGARPSNAGYQYTLQGNDTA
ALYDWTQKLVTALSAQPELADVSSDVLLGDLALDVAIDRDTGARTQLTPQLIANTLYDAYGQRPASIIYNHLHQYRVVME
AAPRFWQDPASLRQVWVSVAGGTAQGGTQANTIRVPLATATTATTAAAQSAASFTNQIANTLAGDHSASNGSAVSTGAET
MVPLQVVSQTTPGNIALAVNHEGQAVAATISFNLPTGVPLGRAIQVVDAQVRRLKMPPSIHGAFSGNAAQLQNSASSETL
LIMAALAAVYMVLGILYESYLHPLTILSTLPSAGVGALVALWVFGQQFSLMAIIGGLAVCQALTLFTTPIVYLTLEQMAR
RVTAWRGTMPPGHPNTGLY

Sequences:

>Translated_819_residues
MSVTGLFIRRPVATTLLTLACVLCGVVGYLTLPVADLPNIDFPVIQVQAQEPGGSPEQMASSVAAPLERHLGEIAGLEEM
TSQSSTGPVRLTLQFALSRDVNGAARDVEAAIQAARADLPTTLRQNPQYSKANPNDPPALLLALTSDTMPLPQVYDQASS
LILPRLSQVRGVGLVQLSGSALPAVRVEIDPQALYKFGIGFEDIRAALASANAYTPKGFIDQDGQRLTLETNDQARDAQA
YRDLVIAYRNGRAVRLTDVAQVVDGVEDVRNAGYYNRKPAIVVQVFMQAGGNIVQALDQIHAEMPQLEAGLPAAIRMQTF
MDRSMTIRASLADTRMTLVLSVVLVVLTVLLFLGTLGVISLLGYSLDNMSLMALTISTGFVVDDAIVVLENVTRHVEKGD
PPLRGRAARRGSSNQGNLFIVLPDKSKRGHPPSTTIGNLNRRSHFMPGHGSHALLRSAIRVGARPSNAGYQYTLQGNDTA
ALYDWTQKLVTALSAQPELADVSSDVLLGDLALDVAIDRDTGARTQLTPQLIANTLYDAYGQRPASIIYNHLHQYRVVME
AAPRFWQDPASLRQVWVSVAGGTAQGGTQANTIRVPLATATTATTAAAQSAASFTNQIANTLAGDHSASNGSAVSTGAET
MVPLQVVSQTTPGNIALAVNHEGQAVAATISFNLPTGVPLGRAIQVVDAQVRRLKMPPSIHGAFSGNAAQLQNSASSETL
LIMAALAAVYMVLGILYESYLHPLTILSTLPSAGVGALVALWVFGQQFSLMAIIGGLAVCQALTLFTTPIVYLTLEQMAR
RVTAWRGTMPPGHPNTGLY
>Mature_818_residues
SVTGLFIRRPVATTLLTLACVLCGVVGYLTLPVADLPNIDFPVIQVQAQEPGGSPEQMASSVAAPLERHLGEIAGLEEMT
SQSSTGPVRLTLQFALSRDVNGAARDVEAAIQAARADLPTTLRQNPQYSKANPNDPPALLLALTSDTMPLPQVYDQASSL
ILPRLSQVRGVGLVQLSGSALPAVRVEIDPQALYKFGIGFEDIRAALASANAYTPKGFIDQDGQRLTLETNDQARDAQAY
RDLVIAYRNGRAVRLTDVAQVVDGVEDVRNAGYYNRKPAIVVQVFMQAGGNIVQALDQIHAEMPQLEAGLPAAIRMQTFM
DRSMTIRASLADTRMTLVLSVVLVVLTVLLFLGTLGVISLLGYSLDNMSLMALTISTGFVVDDAIVVLENVTRHVEKGDP
PLRGRAARRGSSNQGNLFIVLPDKSKRGHPPSTTIGNLNRRSHFMPGHGSHALLRSAIRVGARPSNAGYQYTLQGNDTAA
LYDWTQKLVTALSAQPELADVSSDVLLGDLALDVAIDRDTGARTQLTPQLIANTLYDAYGQRPASIIYNHLHQYRVVMEA
APRFWQDPASLRQVWVSVAGGTAQGGTQANTIRVPLATATTATTAAAQSAASFTNQIANTLAGDHSASNGSAVSTGAETM
VPLQVVSQTTPGNIALAVNHEGQAVAATISFNLPTGVPLGRAIQVVDAQVRRLKMPPSIHGAFSGNAAQLQNSASSETLL
IMAALAAVYMVLGILYESYLHPLTILSTLPSAGVGALVALWVFGQQFSLMAIIGGLAVCQALTLFTTPIVYLTLEQMARR
VTAWRGTMPPGHPNTGLY

Specific function: Could Be A Drug Efflux Pump (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788391, Length=440, Percent_Identity=51.5909090909091, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1788390, Length=435, Percent_Identity=45.0574712643678, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1788814, Length=439, Percent_Identity=28.9293849658314, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI1789930, Length=427, Percent_Identity=29.7423887587822, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1786667, Length=438, Percent_Identity=28.0821917808219, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1789666, Length=442, Percent_Identity=28.0542986425339, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1786788, Length=427, Percent_Identity=22.4824355971897, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 87106; Mature: 86975

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTGLFIRRPVATTLLTLACVLCGVVGYLTLPVADLPNIDFPVIQVQAQEPGGSPEQMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHH
SSVAAPLERHLGEIAGLEEMTSQSSTGPVRLTLQFALSRDVNGAARDVEAAIQAARADLP
HHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
TTLRQNPQYSKANPNDPPALLLALTSDTMPLPQVYDQASSLILPRLSQVRGVGLVQLSGS
HHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
ALPAVRVEIDPQALYKFGIGFEDIRAALASANAYTPKGFIDQDGQRLTLETNDQARDAQA
CCCEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHH
YRDLVIAYRNGRAVRLTDVAQVVDGVEDVRNAGYYNRKPAIVVQVFMQAGGNIVQALDQI
HHHHEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
HAEMPQLEAGLPAAIRMQTFMDRSMTIRASLADTRMTLVLSVVLVVLTVLLFLGTLGVIS
HHHCCHHHCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSLDNMSLMALTISTGFVVDDAIVVLENVTRHVEKGDPPLRGRAARRGSSNQGNLFI
HHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEE
VLPDKSKRGHPPSTTIGNLNRRSHFMPGHGSHALLRSAIRVGARPSNAGYQYTLQGNDTA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
ALYDWTQKLVTALSAQPELADVSSDVLLGDLALDVAIDRDTGARTQLTPQLIANTLYDAY
HHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
GQRPASIIYNHLHQYRVVMEAAPRFWQDPASLRQVWVSVAGGTAQGGTQANTIRVPLATA
CCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEC
TTATTAAAQSAASFTNQIANTLAGDHSASNGSAVSTGAETMVPLQVVSQTTPGNIALAVN
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCCEEEEEE
HEGQAVAATISFNLPTGVPLGRAIQVVDAQVRRLKMPPSIHGAFSGNAAQLQNSASSETL
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHH
LIMAALAAVYMVLGILYESYLHPLTILSTLPSAGVGALVALWVFGQQFSLMAIIGGLAVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
QALTLFTTPIVYLTLEQMARRVTAWRGTMPPGHPNTGLY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVTGLFIRRPVATTLLTLACVLCGVVGYLTLPVADLPNIDFPVIQVQAQEPGGSPEQMA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHH
SSVAAPLERHLGEIAGLEEMTSQSSTGPVRLTLQFALSRDVNGAARDVEAAIQAARADLP
HHHHHHHHHHHHHHHCHHHHHCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCC
TTLRQNPQYSKANPNDPPALLLALTSDTMPLPQVYDQASSLILPRLSQVRGVGLVQLSGS
HHHHCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCC
ALPAVRVEIDPQALYKFGIGFEDIRAALASANAYTPKGFIDQDGQRLTLETNDQARDAQA
CCCEEEEEECHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHH
YRDLVIAYRNGRAVRLTDVAQVVDGVEDVRNAGYYNRKPAIVVQVFMQAGGNIVQALDQI
HHHHEEEECCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
HAEMPQLEAGLPAAIRMQTFMDRSMTIRASLADTRMTLVLSVVLVVLTVLLFLGTLGVIS
HHHCCHHHCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGYSLDNMSLMALTISTGFVVDDAIVVLENVTRHVEKGDPPLRGRAARRGSSNQGNLFI
HHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCEEE
VLPDKSKRGHPPSTTIGNLNRRSHFMPGHGSHALLRSAIRVGARPSNAGYQYTLQGNDTA
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
ALYDWTQKLVTALSAQPELADVSSDVLLGDLALDVAIDRDTGARTQLTPQLIANTLYDAY
HHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHH
GQRPASIIYNHLHQYRVVMEAAPRFWQDPASLRQVWVSVAGGTAQGGTQANTIRVPLATA
CCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEC
TTATTAAAQSAASFTNQIANTLAGDHSASNGSAVSTGAETMVPLQVVSQTTPGNIALAVN
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHCCCCCCEEEEEE
HEGQAVAATISFNLPTGVPLGRAIQVVDAQVRRLKMPPSIHGAFSGNAAQLQNSASSETL
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCHH
LIMAALAAVYMVLGILYESYLHPLTILSTLPSAGVGALVALWVFGQQFSLMAIIGGLAVC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
QALTLFTTPIVYLTLEQMARRVTAWRGTMPPGHPNTGLY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA