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The map label for this gene is ttuB [H]

Identifier: 162146448

GI number: 162146448

Start: 633476

End: 634792

Strand: Direct

Name: ttuB [H]

Synonym: GDI_0624

Alternate gene names: 162146448

Gene position: 633476-634792 (Clockwise)

Preceding gene: 162146446

Following gene: 162146449

Centisome position: 16.06

GC content: 67.88

Gene sequence:

>1317_bases
ATGCACGGAAACGCCCCCCTCTCGCCGCCGGCGGATGACCATCGGTTGGATGCGACCTTCCGCAAGGTCACGCTCGGCCT
GGTGCCCTATATTTTCGCCTGTTACCTATTCAATTATCTCGACCGGGTGAATGTCGGCTTCGCCAAGCTCGACATGCTCG
ATTCCCTGCACATGACCGAACGCGCCTATGGTCTGGCGGCGGGGATCTTCTTCCTGGGCTATATCGCCTGCGGCGTACCC
AGCAACCTGATGCTGCAGCGCGTCGGCGCCCGGCGCTGGCTGGCGCTGATCATGATCGTCTGGGGCGCCCTGTCCGCCGC
GCAGATGTTCGTTCGCGGTCCGGCCAGCTTCTATGCGCTGCGCCTGGCCACCGGGGCCGCGGAGTCCGGCTTCTTTCCCG
GTCTCGTCCTGTATCTGACCCGCTGGTTTCCCTCGGCACGGCACGGGCGGGTGCTGACCCTGTTCATGGCCGCGATTCCA
CTTTCGGGCGTCATCGGCGGCCCGCTCTCGGGCTGGATGCTGGGGCACTTCGCCGCGTCCCCTGGCGGAATCGCCGCCTG
GCAGTGGCTGTTCCTGCTGCAGGGGCTGCCGACCGTGCTGCTCGGGATCGGCATGATGTTCCTGCTCAGCGATACGATCG
GCCAGGTGCGATGGCTGACGGCGGCGGAACGCGCGGCGGTGCAGGATGCGCTGGATCGCGACCGGCTGGACCAGCCGCCC
CGCCTGGCCGACAGTTTCGGCGCCGTGCTGCGCAATCCGGCGATCTGGATGCTGGGGTTGCTGTATTTCTGTACCCAGGC
CGGGGTGTACGCGATCAATTTCTGGCTGCCCAGCATCATCCGCACCAGCGGCGTCCACGATCCGGCGGCGATCGGCTGGC
TCAGCGCGATTCCCTATCTGGCGGCCACCATCTTCATGATCCTGATGGGCCGGTCGGCCGATCGCCGGCGCGAACGGCGC
TGGCACCTTGCCATTCCGCTGCTGATGGCGGCGGCCGGGCTGGCGGTGGCCGCCCGCTTCCCGGACGACACCCCGGTGGC
CCTGGCGGCGCTGACCGTCGCCACGGCCGGCGCGCTGACCGGCTTGCCGATGTTCTGGCCGCTTTGCGGCGGTTATCTCA
GTCCCGCGGCGGCGGCGGGCGGTCTCGCCCTCATCAACTCGATGGGGCAGATGGCGGGATTCGTCAGCCCCTATCTGGTC
GGCTGGGTCAAGGACATGACCCACCGCACTGACGGCGCGCTGTACCTGCTGGCGGGCCTCGCCATCCTCGGCGTGACACT
GGTGCTGCGTATGTCGCCAGCCCGCGTAAACCGCTGA

Upstream 100 bases:

>100_bases
ATCATTCGGCCGTAGCATCAGCGAAACCCTCCAGACGCAGGTGCGTGTGGAGGAGGAAAAAAAGAACAAGGGGCTGTCTC
AAAAGCCTCGGGGATGAACG

Downstream 100 bases:

>100_bases
TATCTCGCGCTGATGTTGGGCCATCCAGAAACAGCCGAGGGGAACCGGCCATGAAGATCGTCATCGTCTGCGACTCGTTC
AAGGAAAGCCTGTCGGCCCT

Product: transporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MHGNAPLSPPADDHRLDATFRKVTLGLVPYIFACYLFNYLDRVNVGFAKLDMLDSLHMTERAYGLAAGIFFLGYIACGVP
SNLMLQRVGARRWLALIMIVWGALSAAQMFVRGPASFYALRLATGAAESGFFPGLVLYLTRWFPSARHGRVLTLFMAAIP
LSGVIGGPLSGWMLGHFAASPGGIAAWQWLFLLQGLPTVLLGIGMMFLLSDTIGQVRWLTAAERAAVQDALDRDRLDQPP
RLADSFGAVLRNPAIWMLGLLYFCTQAGVYAINFWLPSIIRTSGVHDPAAIGWLSAIPYLAATIFMILMGRSADRRRERR
WHLAIPLLMAAAGLAVAARFPDDTPVALAALTVATAGALTGLPMFWPLCGGYLSPAAAAGGLALINSMGQMAGFVSPYLV
GWVKDMTHRTDGALYLLAGLAILGVTLVLRMSPARVNR

Sequences:

>Translated_438_residues
MHGNAPLSPPADDHRLDATFRKVTLGLVPYIFACYLFNYLDRVNVGFAKLDMLDSLHMTERAYGLAAGIFFLGYIACGVP
SNLMLQRVGARRWLALIMIVWGALSAAQMFVRGPASFYALRLATGAAESGFFPGLVLYLTRWFPSARHGRVLTLFMAAIP
LSGVIGGPLSGWMLGHFAASPGGIAAWQWLFLLQGLPTVLLGIGMMFLLSDTIGQVRWLTAAERAAVQDALDRDRLDQPP
RLADSFGAVLRNPAIWMLGLLYFCTQAGVYAINFWLPSIIRTSGVHDPAAIGWLSAIPYLAATIFMILMGRSADRRRERR
WHLAIPLLMAAAGLAVAARFPDDTPVALAALTVATAGALTGLPMFWPLCGGYLSPAAAAGGLALINSMGQMAGFVSPYLV
GWVKDMTHRTDGALYLLAGLAILGVTLVLRMSPARVNR
>Mature_438_residues
MHGNAPLSPPADDHRLDATFRKVTLGLVPYIFACYLFNYLDRVNVGFAKLDMLDSLHMTERAYGLAAGIFFLGYIACGVP
SNLMLQRVGARRWLALIMIVWGALSAAQMFVRGPASFYALRLATGAAESGFFPGLVLYLTRWFPSARHGRVLTLFMAAIP
LSGVIGGPLSGWMLGHFAASPGGIAAWQWLFLLQGLPTVLLGIGMMFLLSDTIGQVRWLTAAERAAVQDALDRDRLDQPP
RLADSFGAVLRNPAIWMLGLLYFCTQAGVYAINFWLPSIIRTSGVHDPAAIGWLSAIPYLAATIFMILMGRSADRRRERR
WHLAIPLLMAAAGLAVAARFPDDTPVALAALTVATAGALTGLPMFWPLCGGYLSPAAAAGGLALINSMGQMAGFVSPYLV
GWVKDMTHRTDGALYLLAGLAILGVTLVLRMSPARVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=425, Percent_Identity=22.1176470588235, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082071, Length=430, Percent_Identity=34.1860465116279, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=25.4716981132075, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789152, Length=422, Percent_Identity=20.6161137440758, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082320, Length=296, Percent_Identity=22.972972972973, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789515, Length=427, Percent_Identity=21.3114754098361, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=190, Percent_Identity=26.3157894736842, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=445, Percent_Identity=24.4943820224719, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=333, Percent_Identity=20.7207207207207, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=145, Percent_Identity=29.6551724137931, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=295, Percent_Identity=25.0847457627119, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584153, Length=357, Percent_Identity=22.1288515406162, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20130167, Length=428, Percent_Identity=21.0280373831776, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47265; Mature: 47265

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCHHHCCC
>Mature Secondary Structure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HHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]