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The map label for this gene is oxyR [H]

Identifier: 162146403

GI number: 162146403

Start: 585360

End: 586292

Strand: Direct

Name: oxyR [H]

Synonym: GDI_0578

Alternate gene names: 162146403

Gene position: 585360-586292 (Clockwise)

Preceding gene: 162146402

Following gene: 162146404

Centisome position: 14.84

GC content: 69.13

Gene sequence:

>933_bases
ATGACACCTCTGCCTTCGGCACAACAATTGCGGTACCTGATCACGCTGGCGGAACTGCGTCATTTCGGCCGTGCGGCGCT
GGCCTGTTCGGTCACGCAATCGACGCTGTCGGCCGGAATCCTGGCCCTGGAGCGGCAGTTGGACGTCCAGTTGCTGGACC
GCAACGTCGGCAAGCGCGTGGTCTTCACCCCCATCGGCGACGAAGTCGCCGCCCGGGCGCGATTCGCCCTGGAGACGCTG
CAGGCGGTGCAGGACGTGGCCGATGCCTCGCGCGCGCCCATGACCGGGCTGCTGCGGATCGGGGTCATTCCCACCATCGG
CCCCTTCATCATGCCCGGGCTGGTGTCGCGCCTGCGCCGGCAATTCCCCCAGATCCGCCTGTCGGTGAACGAGGACCTGA
CCGGCAACGTGATGGACAAGCTGGCGCTGGGCCGGCTGGACCTGGTGCTGCTGGCCATGCCCTGCCCGTGCGAAGGCACG
GAAACCCTGCCCCTGTGGCGGGACGAATTCATGCTGCTGCTGCCGGCCGACCATGCGCTGGCCGCCCTCGACTCGATTCC
CGTCGAACGGATCGCGGGCGAACGCATGGTGCTGCTGGAAGACGGCCACTGCCTGCGCGAACAGACGCTGTCGCTATGCC
GGCAGGAACGGGGCTGGAGCACCCCGGACGGGGACGAGGAATTCGTCGTGACCTCGCTCTATACCCTGGTGGACATGGTG
GCGGAGGGGCTGGGAATCGCCCTTCTGCCGCGTCTGGCGGTGGAATCGGGAATCCTGCGCGACCTGCCGCTCGTCGTCCG
GCCGGTGACGGGCTGCCAGGCCTGGCGCACGATCGGGCTGGCCTGGCGCCCGCGCTCGCCCCGCGCGGCCGACTTCCGCC
AGCTTGGCCTGCATATCCGCCCGCCTGCCGTTACCGCCCCCGCCATGGTGTGA

Upstream 100 bases:

>100_bases
GGCGCCCTGAACAGGCGGTCCGGCCTCGGACTGTATTTTATGGCGTTGAAGCCTATATCATGCCAATGAATAATTTATAT
CCGGACAATCGAAAGAATCG

Downstream 100 bases:

>100_bases
AAAAACACATCCATGGGCGGAAAGTCAGGCATGGGGCGGGGGTGTGCGGTTGACTCCGTGCCGTGGGACCGGTATTCGGC
CCGTCTTTGCGGTTTCCTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTPLPSAQQLRYLITLAELRHFGRAALACSVTQSTLSAGILALERQLDVQLLDRNVGKRVVFTPIGDEVAARARFALETL
QAVQDVADASRAPMTGLLRIGVIPTIGPFIMPGLVSRLRRQFPQIRLSVNEDLTGNVMDKLALGRLDLVLLAMPCPCEGT
ETLPLWRDEFMLLLPADHALAALDSIPVERIAGERMVLLEDGHCLREQTLSLCRQERGWSTPDGDEEFVVTSLYTLVDMV
AEGLGIALLPRLAVESGILRDLPLVVRPVTGCQAWRTIGLAWRPRSPRAADFRQLGLHIRPPAVTAPAMV

Sequences:

>Translated_310_residues
MTPLPSAQQLRYLITLAELRHFGRAALACSVTQSTLSAGILALERQLDVQLLDRNVGKRVVFTPIGDEVAARARFALETL
QAVQDVADASRAPMTGLLRIGVIPTIGPFIMPGLVSRLRRQFPQIRLSVNEDLTGNVMDKLALGRLDLVLLAMPCPCEGT
ETLPLWRDEFMLLLPADHALAALDSIPVERIAGERMVLLEDGHCLREQTLSLCRQERGWSTPDGDEEFVVTSLYTLVDMV
AEGLGIALLPRLAVESGILRDLPLVVRPVTGCQAWRTIGLAWRPRSPRAADFRQLGLHIRPPAVTAPAMV
>Mature_309_residues
TPLPSAQQLRYLITLAELRHFGRAALACSVTQSTLSAGILALERQLDVQLLDRNVGKRVVFTPIGDEVAARARFALETLQ
AVQDVADASRAPMTGLLRIGVIPTIGPFIMPGLVSRLRRQFPQIRLSVNEDLTGNVMDKLALGRLDLVLLAMPCPCEGTE
TLPLWRDEFMLLLPADHALAALDSIPVERIAGERMVLLEDGHCLREQTLSLCRQERGWSTPDGDEEFVVTSLYTLVDMVA
EGLGIALLPRLAVESGILRDLPLVVRPVTGCQAWRTIGLAWRPRSPRAADFRQLGLHIRPPAVTAPAMV

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=295, Percent_Identity=38.9830508474576, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=30.3754266211604, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=30.9859154929577, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788748, Length=271, Percent_Identity=28.0442804428044, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=26.1904761904762, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=249, Percent_Identity=27.710843373494, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787806, Length=284, Percent_Identity=24.6478873239437, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367136, Length=241, Percent_Identity=28.2157676348548, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=254, Percent_Identity=28.3464566929134, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788887, Length=284, Percent_Identity=23.943661971831, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=25.78125, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787530, Length=258, Percent_Identity=24.031007751938, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788297, Length=248, Percent_Identity=25.4032258064516, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=27.972027972028, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33998; Mature: 33867

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLPSAQQLRYLITLAELRHFGRAALACSVTQSTLSAGILALERQLDVQLLDRNVGKRV
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VFTPIGDEVAARARFALETLQAVQDVADASRAPMTGLLRIGVIPTIGPFIMPGLVSRLRR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
QFPQIRLSVNEDLTGNVMDKLALGRLDLVLLAMPCPCEGTETLPLWRDEFMLLLPADHAL
HCCEEEEEECCCCCHHHHHHHHHCHHCEEEEECCCCCCCCCCCCCCCCCEEEEEECHHHH
AALDSIPVERIAGERMVLLEDGHCLREQTLSLCRQERGWSTPDGDEEFVVTSLYTLVDMV
HHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AEGLGIALLPRLAVESGILRDLPLVVRPVTGCQAWRTIGLAWRPRSPRAADFRQLGLHIR
HHCCCHHHHHHHHHHCCHHHCCCHHEECCCCHHHHHHCCEEECCCCCCHHHHHHCCCEEC
PPAVTAPAMV
CCCCCCCCCC
>Mature Secondary Structure 
TPLPSAQQLRYLITLAELRHFGRAALACSVTQSTLSAGILALERQLDVQLLDRNVGKRV
CCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VFTPIGDEVAARARFALETLQAVQDVADASRAPMTGLLRIGVIPTIGPFIMPGLVSRLRR
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHH
QFPQIRLSVNEDLTGNVMDKLALGRLDLVLLAMPCPCEGTETLPLWRDEFMLLLPADHAL
HCCEEEEEECCCCCHHHHHHHHHCHHCEEEEECCCCCCCCCCCCCCCCCEEEEEECHHHH
AALDSIPVERIAGERMVLLEDGHCLREQTLSLCRQERGWSTPDGDEEFVVTSLYTLVDMV
HHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
AEGLGIALLPRLAVESGILRDLPLVVRPVTGCQAWRTIGLAWRPRSPRAADFRQLGLHIR
HHCCCHHHHHHHHHHCCHHHCCCHHEECCCCHHHHHHCCEEECCCCCCHHHHHHCCCEEC
PPAVTAPAMV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]